FI931488A - Tnf-muteiner - Google Patents

Tnf-muteiner Download PDF

Info

Publication number
FI931488A
FI931488A FI931488A FI931488A FI931488A FI 931488 A FI931488 A FI 931488A FI 931488 A FI931488 A FI 931488A FI 931488 A FI931488 A FI 931488A FI 931488 A FI931488 A FI 931488A
Authority
FI
Finland
Prior art keywords
muteiner
tnf
Prior art date
Application number
FI931488A
Other languages
English (en)
Other versions
FI931488A0 (fi
Inventor
Werner Lesslauer
Hansruedi Loetscher
Dietrich Stueber
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of FI931488A0 publication Critical patent/FI931488A0/fi
Publication of FI931488A publication Critical patent/FI931488A/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/525—Tumour necrosis factor [TNF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
FI931488A 1992-04-02 1993-04-01 Tnf-muteiner FI931488A (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP92810249 1992-04-02

Publications (2)

Publication Number Publication Date
FI931488A0 FI931488A0 (fi) 1993-04-01
FI931488A true FI931488A (fi) 1993-10-03

Family

ID=8211902

Family Applications (1)

Application Number Title Priority Date Filing Date
FI931488A FI931488A (fi) 1992-04-02 1993-04-01 Tnf-muteiner

Country Status (19)

Country Link
US (1) US5486463A (fi)
EP (1) EP0563714A3 (fi)
JP (1) JPH07285997A (fi)
CN (1) CN1037844C (fi)
AU (1) AU659927B2 (fi)
BR (1) BR9301420A (fi)
CA (1) CA2091313A1 (fi)
CZ (1) CZ283533B6 (fi)
FI (1) FI931488A (fi)
HU (1) HUT69790A (fi)
IL (1) IL105170A0 (fi)
MX (1) MX9301700A (fi)
NO (1) NO931141L (fi)
NZ (1) NZ247265A (fi)
PL (1) PL298345A1 (fi)
SK (1) SK376492A3 (fi)
TW (1) TW260707B (fi)
UY (1) UY23561A1 (fi)
ZA (1) ZA932177B (fi)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR970005042B1 (ko) * 1993-02-09 1997-04-11 한일합성섬유공업 주식회사 종양괴사인자-알파 뮤테인
CA2119089A1 (en) * 1993-03-29 1994-09-30 David Banner Tumor necrosis factor muteins
CN1049663C (zh) * 1994-09-01 2000-02-23 中国科学院上海生物工程研究中心 突变的人肿瘤坏死因子
US7070771B1 (en) 1996-12-09 2006-07-04 Regents Of The University Of California Methods of expressing chimeric mouse and human CD40 ligand in human CD40+ cells
US20020077276A1 (en) * 1999-04-27 2002-06-20 Fredeking Terry M. Compositions and methods for treating hemorrhagic virus infections and other disorders
US6379708B1 (en) * 1999-11-20 2002-04-30 Cytologic, Llc Method for enhancing immune responses in mammals
CA2396793A1 (en) * 2000-02-16 2001-08-23 Genentech, Inc. Uses of agonists and antagonists to modulate activity of tnf-related molecules
HUP0500992A3 (en) * 2001-08-03 2007-11-28 Genentech Inc Tacis and br3 polypeptides and uses thereof
US7786282B2 (en) * 2001-12-06 2010-08-31 The Regents Of The University Of California Nucleic acid molecules encoding TNF-α ligand polypeptides having a CD154 domain
US20030199024A1 (en) * 2002-04-19 2003-10-23 Hansen Ted H. Single chain trimers of class I MHC molecules
CN1692127A (zh) * 2002-07-25 2005-11-02 健泰科生物技术公司 Taci抗体及其用途
MXPA05005921A (es) * 2002-12-02 2005-10-19 Abgenix Inc Anticuerpos dirigidos a factor de necrosis tumoral y sus usos.
US20040121971A1 (en) * 2002-12-20 2004-06-24 Gang Chen Therapeutic use of tumor necrosis factor-alpha mutein
KR20060027801A (ko) * 2003-06-05 2006-03-28 제넨테크, 인크. Ｂ 세포 장애에 대한 조합 요법
US20050163775A1 (en) * 2003-06-05 2005-07-28 Genentech, Inc. Combination therapy for B cell disorders
CN100390200C (zh) * 2003-11-24 2008-05-28 中国医学科学院基础医学研究所 一种用于治疗获得性免疫缺陷综合征的重组靶向融合蛋白
TW200526780A (en) * 2004-01-06 2005-08-16 Hayashibara Biochem Lab TNF antagonists and TNF inhibitors comprising the same as the active ingredient
CN1752211B (zh) * 2004-09-23 2010-09-15 中国医学科学院基础医学研究所 用于治疗获得性免疫缺陷综合征的重组靶向融合蛋白
GB0425972D0 (en) 2004-11-25 2004-12-29 Celltech R&D Ltd Biological products
US7850960B2 (en) 2004-12-30 2010-12-14 University Of Washington Methods for regulation of stem cells
US20070065514A1 (en) * 2005-09-22 2007-03-22 Howell Mark D Method for enhancing immune responses in mammals
WO2007062090A2 (en) * 2005-11-23 2007-05-31 Genentech, Inc. Methods and compositions related to b cell assays
US8518697B2 (en) * 2006-04-04 2013-08-27 Washington University Single chain trimers and uses therefor
WO2008019394A2 (en) * 2006-08-11 2008-02-14 The Government Of The United States Of America As Represented By The Secretary, Dept Of Health And Human Services Methods for treatment and diagnosis of psychiatric disorders
WO2008127515A1 (en) * 2007-03-01 2008-10-23 Cytologic, Inc. Compositions and method for enhancing immune responses in mammals
PL2953634T3 (pl) 2013-02-07 2021-11-22 The General Hospital Corporation Sposoby namnażania lub zubożania limfocytów t-regulatorowych
US11224858B1 (en) 2020-10-01 2022-01-18 Immunicom, Inc. Reduced leaching of a ligand
AU2020470781A1 (en) 2020-10-01 2023-05-18 Immunicom, Inc. Reduced leaching of a ligand

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07106158B2 (ja) * 1986-12-04 1995-11-15 サントリー株式会社 抗腫瘍活性を有する新規ポリペプチドおよびその製造法
CA2055168A1 (en) * 1990-11-21 1992-05-22 Walter Fiers Tnf-muteins

Also Published As

Publication number Publication date
CZ283533B6 (cs) 1998-04-15
CN1079225A (zh) 1993-12-08
HU9300843D0 (en) 1993-06-28
EP0563714A2 (en) 1993-10-06
NO931141L (no) 1993-10-04
JPH07285997A (ja) 1995-10-31
BR9301420A (pt) 1993-10-05
PL298345A1 (en) 1993-12-27
CA2091313A1 (en) 1993-10-03
AU659927B2 (en) 1995-06-01
ZA932177B (en) 1993-10-04
AU3561193A (en) 1993-10-07
NO931141D0 (no) 1993-03-26
SK376492A3 (en) 1995-06-07
FI931488A0 (fi) 1993-04-01
HUT69790A (en) 1995-09-28
EP0563714A3 (en) 1993-11-10
CZ376492A3 (en) 1994-01-19
NZ247265A (en) 1995-10-26
CN1037844C (zh) 1998-03-25
TW260707B (fi) 1995-10-21
IL105170A0 (en) 1993-07-08
US5486463A (en) 1996-01-23
MX9301700A (es) 1993-10-29
UY23561A1 (es) 1993-09-20

Similar Documents

Publication Publication Date Title
DE59303358D1 (de) Quaterrylentetracarbonsäureimide
DE59306810D1 (de) Gutbettwalzenmühle
FI931488A (fi) Tnf-muteiner
DE59302851D1 (de) Sportschuh
BR9305745A (pt) Quebra-luz
DE59301902D1 (de) Kassenlade
FI925132A0 (fi) Foersaeljningsstaellning foer flaskor
DE59305364D1 (de) Rotornut
DE69304512T2 (de) Laseroszillator
FI930779A (fi) Insulationsmaterial
FI932941A (fi) Insprutningsanordning
FI932281A0 (fi) Ettkaerlsfoerfarande
DE59304139D1 (de) Polyanile
BR9301712A (pt) Aplainador
ATA227792A (de) Sportschuh
DE59309200D1 (de) Bisphosphinoalkane
DE59301762D1 (de) Chlorethylsulfonylbenzaldehyde
FI456U1 (fi) Lyftlaenk
FI667U1 (fi) Bevattningsanordning foer plantskolor
DE59206388D1 (de) Kabeleckkanal
FI774U1 (fi) Bryggkonstruktion
BR9202687A (pt) Minhoqueira
BR9201149A (pt) Mutlimovel
BR9204074A (pt) Contramarco pre-moldano
BR9204065A (pt) Soprocóptero