FI930048A0 - Kemiska foereningar - Google Patents

Kemiska foereningar

Info

Publication number
FI930048A0
FI930048A0 FI930048A FI930048A FI930048A0 FI 930048 A0 FI930048 A0 FI 930048A0 FI 930048 A FI930048 A FI 930048A FI 930048 A FI930048 A FI 930048A FI 930048 A0 FI930048 A0 FI 930048A0
Authority
FI
Finland
Prior art keywords
image
alkyl
hal
halogen
represent
Prior art date
Application number
FI930048A
Other languages
English (en)
Other versions
FI111361B (fi
FI930048A (fi
Inventor
Robert R Bartlett
David P Kay
Elizabeth A Kuo
Rudolf Schleyerbach
Wilfried Schwab
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of FI930048A0 publication Critical patent/FI930048A0/fi
Publication of FI930048A publication Critical patent/FI930048A/fi
Application granted granted Critical
Publication of FI111361B publication Critical patent/FI111361B/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
    • C07C255/19—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and carboxyl groups, other than cyano groups, bound to the same saturated acyclic carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/275—Nitriles; Isonitriles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
    • C07C255/23—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and carboxyl groups, other than cyano groups, bound to the same unsaturated acyclic carbon skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
FI930048A 1992-01-08 1993-01-07 Menetelmä terapeuttisesti käyttökelpoisten 2-syano-3-hydroksienamidien valmistamiseksi FI111361B (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB929200275A GB9200275D0 (en) 1992-01-08 1992-01-08 Chemical compounds
GB9200275 1992-01-08

Publications (3)

Publication Number Publication Date
FI930048A0 true FI930048A0 (fi) 1993-01-07
FI930048A FI930048A (fi) 1993-07-09
FI111361B FI111361B (fi) 2003-07-15

Family

ID=10708234

Family Applications (1)

Application Number Title Priority Date Filing Date
FI930048A FI111361B (fi) 1992-01-08 1993-01-07 Menetelmä terapeuttisesti käyttökelpoisten 2-syano-3-hydroksienamidien valmistamiseksi

Country Status (22)

Country Link
US (1) US5308865A (fi)
EP (1) EP0551230B1 (fi)
JP (1) JP3145824B2 (fi)
KR (1) KR100276182B1 (fi)
CN (1) CN1034499C (fi)
AT (1) ATE125252T1 (fi)
AU (1) AU652088B2 (fi)
BR (1) BR9300035A (fi)
CA (1) CA2086908C (fi)
CZ (1) CZ285586B6 (fi)
DE (1) DE69300261T2 (fi)
DK (1) DK0551230T3 (fi)
ES (1) ES2074916T3 (fi)
FI (1) FI111361B (fi)
GB (1) GB9200275D0 (fi)
HU (1) HU215843B (fi)
IL (1) IL104225A (fi)
NO (1) NO179444C (fi)
NZ (1) NZ245631A (fi)
RU (1) RU2112772C1 (fi)
TW (1) TW234116B (fi)
ZA (1) ZA93134B (fi)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994024095A1 (en) * 1993-04-16 1994-10-27 Abbott Laboratories Immunosuppressive agents
GB9313365D0 (en) * 1993-06-29 1993-08-11 Roussel Lab Ltd Chemical compounds
GB9322781D0 (en) * 1993-11-04 1993-12-22 Roussel Lab Ltd Aromatic amides
US5610173A (en) * 1994-01-07 1997-03-11 Sugen, Inc. Formulations for lipophilic compounds
US6335356B1 (en) 1994-01-07 2002-01-01 Sugen, Inc. Method of treating a patient by parenteral administration of a lipophilic compound
US5700823A (en) * 1994-01-07 1997-12-23 Sugen, Inc. Treatment of platelet derived growth factor related disorders such as cancers
US5721277A (en) * 1995-04-21 1998-02-24 Sugen, Inc. Compounds and methods for inhibiting hyper-proliferative cell growth
GB9520092D0 (en) * 1995-10-02 1995-12-06 Hoechst Roussel Ltd Chemical compounds
DE19539638A1 (de) * 1995-10-25 1997-04-30 Hoechst Ag Die Verwendung von Isoxazol- und Crotonsäureamidderivaten zur Behandlung von Krebserkrankungen
DE19547648A1 (de) * 1995-12-20 1997-06-26 Hoechst Ag Zubereitung, enthaltend High Density Lipoproteine und Crotonsäureamidderivate
US5856330A (en) * 1996-07-31 1999-01-05 Hoechst Aktiengesellschaft Use of xanthine derivatives for the inhibition of dephosphorylation of cofilin
US6011051A (en) * 1996-07-31 2000-01-04 Hoechst Aktiengesellschaft Use of isoxazole and crotonamide derivatives for the modulation of apoptosis
US5981536A (en) * 1996-07-31 1999-11-09 Hoechst Aktiengesellschaft Use of xanthine derivatives for the modulation of apoptosis
DE19702988A1 (de) * 1997-01-28 1998-07-30 Hoechst Ag Isoxazol- und Crotonsäureamidderivate und deren Verwendung als Arzneimittel und Diagnostika
DE19711800A1 (de) * 1997-03-21 1998-09-24 Hoechst Ag Verlängerung der Expression von transgenen Proteinen durch immunmodulierende Behandlung
US6316479B1 (en) 1997-05-19 2001-11-13 Sugen, Inc. Isoxazole-4-carboxamide compounds active against protein tryosine kinase related disorders
KR20010042804A (ko) * 1998-04-17 2001-05-25 파커 휴우즈 인스티튜트 비티케이 억제제와 그들의 동정 방법 및 용도
US6303652B1 (en) 1998-08-21 2001-10-16 Hughes Institute BTK inhibitors and methods for their identification and use
EP1494669A1 (en) * 2002-04-16 2005-01-12 Fujisawa Pharmaceutical Co., Ltd. Medicament for preventing and/or treating chronic rejection
EP1609778A1 (en) * 2003-03-24 2005-12-28 Astellas Pharma Inc. Process for production of 2-cyano-3-hydroxy-n-(4-tri- fluoromethylphenyl)hept-2-en-6-ynamide and process for production of polymorphs thereof
US20070178544A1 (en) * 2004-03-05 2007-08-02 Kouichi Tamura Anti fk778antibodies and high sensitive immunoassay methods
DE102005017592A1 (de) * 2005-04-16 2006-10-19 Lindner, Jürgen, Dr. med. Darreichungsformen und Kombinationspräparate von Pyrimidinbiosyntheseinhibitoren zur Erzielung zusätzlicher Wirkungen auf das Immunsystem
RU2526201C2 (ru) * 2007-11-16 2014-08-20 Эббви Инк. Способ лечения артрита
LT2632451T (lt) 2010-10-29 2018-02-12 Algiax Pharmaceuticals Gmbh Malononitrilamidų panaudojimas esant neuropatiniam skausmui
TN2016000197A1 (en) 2013-11-22 2017-10-06 Genzyme Corp Novel methods for treating neurodegenerative diseases.
CN112979509B (zh) * 2021-03-10 2022-04-22 江西师范大学 一种三氟甲磺酰基炔酰胺类化合物及其制备方法和用途

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR484223A (fr) * 1916-03-21 1917-09-14 Zenith Carburateur Soc Du Perfectionnements aux carburateurs de moteurs à explosions
NL186239B (nl) * 1975-06-05 Hoechst Ag Werkwijze voor de bereiding van een geneesmiddel met antiflogistische en/of analgetische werking, alsmede werkwijze voor de bereiding van een 2-hydroxyethylideencyaanazijnzuuranilide geschikt voor toepassing bij deze werkwijze.
DE2555789A1 (de) * 1975-12-11 1977-07-07 Hoechst Ag Neue cyanessigsaeureanilid-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende mittel
US4346097A (en) * 1980-09-30 1982-08-24 Warner-Lambert Company Method for treating convulsions with pyrazole-4-carboxamide derivatives
DE3534440A1 (de) * 1985-09-27 1987-04-02 Hoechst Ag Arzneimittel gegen chronische graft-versus-host-krankheiten sowie gegen autoimmunerkrankungen, insbesondere systemischen lupus erythematodes
GB8619432D0 (en) * 1986-08-08 1986-09-17 Lilly Industries Ltd Pharmaceutical compounds
DK0527736T3 (da) * 1990-05-18 1997-10-20 Hoechst Ag Isoxazol-4-carboxylsyreamider og hydroxyalkyliden-cyanoacetamider, lægemidler indeholdende disse forbindelser og anvendelsen af disse lægemidler.
IL99811A (en) * 1990-10-30 1996-03-31 Roussel Uclaf 3-Cycloalkyl-propanamides, tautomeric forms of these, their salts, method of preparation, use as drugs and preparations containing them

Also Published As

Publication number Publication date
BR9300035A (pt) 1993-07-13
CA2086908A1 (en) 1993-07-09
ZA93134B (en) 1994-01-10
HU215843B (hu) 1999-09-28
DE69300261D1 (de) 1995-08-24
RU2112772C1 (ru) 1998-06-10
AU3103593A (en) 1993-07-15
KR930016395A (ko) 1993-08-26
EP0551230A1 (fr) 1993-07-14
TW234116B (en) 1994-11-11
HUT63377A (en) 1993-08-30
CN1034499C (zh) 1997-04-09
KR100276182B1 (ko) 2000-12-15
ATE125252T1 (de) 1995-08-15
GB9200275D0 (en) 1992-02-26
NZ245631A (en) 1994-12-22
DK0551230T3 (da) 1997-03-10
FI111361B (fi) 2003-07-15
JPH05310672A (ja) 1993-11-22
NO179444C (no) 1996-10-09
ES2074916T3 (es) 1995-09-16
AU652088B2 (en) 1994-08-11
NO930036L (no) 1993-07-09
JP3145824B2 (ja) 2001-03-12
CN1079216A (zh) 1993-12-08
CZ382692A3 (en) 1994-03-16
HU9300022D0 (en) 1993-04-28
FI930048A (fi) 1993-07-09
CZ285586B6 (cs) 1999-09-15
NO930036D0 (no) 1993-01-07
NO179444B (no) 1996-07-01
DE69300261T2 (de) 1995-12-07
US5308865A (en) 1994-05-03
CA2086908C (en) 2005-06-14
IL104225A0 (en) 1993-05-13
EP0551230B1 (fr) 1995-07-19
IL104225A (en) 1998-01-04

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Legal Events

Date Code Title Description
GB Transfer or assigment of application

Owner name: HOECHST MARION ROUSSEL

MA Patent expired