FI924982A0 - Frystorkat preparat som innehaoller monoklonal motkropp - Google Patents
Frystorkat preparat som innehaoller monoklonal motkroppInfo
- Publication number
- FI924982A0 FI924982A0 FI924982A FI924982A FI924982A0 FI 924982 A0 FI924982 A0 FI 924982A0 FI 924982 A FI924982 A FI 924982A FI 924982 A FI924982 A FI 924982A FI 924982 A0 FI924982 A0 FI 924982A0
- Authority
- FI
- Finland
- Prior art keywords
- motkropp
- monoklonal
- frystorkat
- preparat
- som innehaoller
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39591—Stabilisation, fragmentation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1203—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
- C07K16/1214—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Pseudomonadaceae (F)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP4343191 | 1991-03-08 | ||
PCT/JP1992/000226 WO1992015331A1 (fr) | 1991-03-08 | 1992-02-28 | Preparation lyophilisee d'anticorps monoclonaux |
Publications (2)
Publication Number | Publication Date |
---|---|
FI924982A0 true FI924982A0 (fi) | 1992-11-04 |
FI924982A FI924982A (fi) | 1992-11-04 |
Family
ID=12663510
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI924982A FI924982A (fi) | 1991-03-08 | 1992-11-04 | Frystorkat preparat som innehaoller monoklonal motkropp |
Country Status (10)
Country | Link |
---|---|
US (1) | US5908826A (fr) |
EP (2) | EP0531539B1 (fr) |
JP (1) | JPH0565233A (fr) |
AU (1) | AU645187B2 (fr) |
CA (1) | CA2082169A1 (fr) |
DE (2) | DE69225757T2 (fr) |
DK (2) | DK0531539T3 (fr) |
FI (1) | FI924982A (fr) |
NO (1) | NO924279D0 (fr) |
WO (1) | WO1992015331A1 (fr) |
Families Citing this family (46)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6800738B1 (en) | 1991-06-14 | 2004-10-05 | Genentech, Inc. | Method for making humanized antibodies |
GB9122820D0 (en) * | 1991-10-28 | 1991-12-11 | Wellcome Found | Stabilised antibodies |
US6685940B2 (en) | 1995-07-27 | 2004-02-03 | Genentech, Inc. | Protein formulation |
IL122910A (en) * | 1995-07-27 | 2002-05-23 | Genentech Inc | Stable isotonic protein formulation that has undergone lyophilization |
JP2014148555A (ja) * | 1995-07-27 | 2014-08-21 | Genentech Inc | タンパク質の処方 |
US6267958B1 (en) | 1995-07-27 | 2001-07-31 | Genentech, Inc. | Protein formulation |
JP3624543B2 (ja) * | 1996-05-02 | 2005-03-02 | 東ソー株式会社 | 免疫反応試薬及びその製造方法 |
EP0852951A1 (fr) | 1996-11-19 | 1998-07-15 | Roche Diagnostics GmbH | Compositions pharmaceutiques stables, lyophilisées d'anticorps monoclonaux ou polyclonaux |
AU2444899A (en) * | 1998-01-22 | 1999-08-09 | Astrazeneca Ab | Pharmaceutical formulation comprising an antibody and a citrate buffer |
US6750330B1 (en) * | 1998-05-14 | 2004-06-15 | Ashley Davis | Lyophilized tubulins |
EP1254666A4 (fr) * | 1999-12-28 | 2004-12-22 | Chugai Pharmaceutical Co Ltd | Compositions d'anticorps stables et preparations pour injection |
US20040038878A1 (en) * | 2000-08-04 | 2004-02-26 | Masahiko Tanikawa | Injectable protein formulations |
US8703126B2 (en) | 2000-10-12 | 2014-04-22 | Genentech, Inc. | Reduced-viscosity concentrated protein formulations |
PT1324776E (pt) | 2000-10-12 | 2009-12-23 | Genentech Inc | Formulações de proteína concentradas de viscosidade reduzida |
GB0113179D0 (en) * | 2001-05-31 | 2001-07-25 | Novartis Ag | Organic compounds |
JP4317010B2 (ja) * | 2001-07-25 | 2009-08-19 | ピーディーエル バイオファーマ,インコーポレイティド | IgG抗体の安定な凍結乾燥医薬製剤 |
US20040002451A1 (en) * | 2002-06-20 | 2004-01-01 | Bruce Kerwin | Compositions of pegylated soluble tumor necrosis factor receptors and methods of preparing |
US20040033228A1 (en) | 2002-08-16 | 2004-02-19 | Hans-Juergen Krause | Formulation of human antibodies for treating TNF-alpha associated disorders |
ZA200507757B (en) | 2003-04-04 | 2007-01-31 | Genentech Inc | High concentration antibody and protein formulations |
TW200510532A (en) | 2003-07-15 | 2005-03-16 | Chugai Pharmaceutical Co Ltd | IgM production by transformed cell and method of quantifying the same |
WO2005035573A1 (fr) * | 2003-10-09 | 2005-04-21 | Chugai Seiyaku Kabushiki Kaisha | Methode de stabilisation de solution proteinique |
ATE518888T1 (de) * | 2003-10-09 | 2011-08-15 | Chugai Pharmaceutical Co Ltd | Stabilisierte lösung mit hoher igm-konzentration |
EP1712240B1 (fr) * | 2003-12-25 | 2015-09-09 | Kyowa Hakko Kirin Co., Ltd. | Preparation medicamenteuse aqueuse stable contenant un anticorps |
AU2006247039B2 (en) * | 2005-05-19 | 2011-03-03 | Amgen Inc. | Compositions and methods for increasing the stability of antibodies |
US20080311078A1 (en) | 2005-06-14 | 2008-12-18 | Gokarn Yatin R | Self-Buffering Protein Formulations |
JP5231810B2 (ja) | 2005-12-28 | 2013-07-10 | 中外製薬株式会社 | 抗体含有安定化製剤 |
AR059066A1 (es) | 2006-01-27 | 2008-03-12 | Amgen Inc | Combinaciones del inhibidor de la angiopoyetina -2 (ang2) y el inhibidor del factor de crecimiento endotelial vascular (vegf) |
TW200831129A (en) * | 2006-10-06 | 2008-08-01 | Amgen Inc | Stable formulations |
AU2007309616B2 (en) * | 2006-10-20 | 2011-10-06 | Amgen Inc. | Stable polypeptide formulations |
WO2008116103A2 (fr) * | 2007-03-22 | 2008-09-25 | Imclone Llc | Formulations d'anticorps stables |
JP5322405B2 (ja) * | 2007-06-07 | 2013-10-23 | 小林製薬株式会社 | タンパク質含有組成物 |
TW201039854A (en) | 2009-03-06 | 2010-11-16 | Genentech Inc | Antibody formulation |
SG10201903166PA (en) | 2010-03-01 | 2019-05-30 | Bayer Healthcare Llc | Optimized monoclonal antibodies against tissue factor pathway inhibitor (tfpi) |
WO2012028683A1 (fr) | 2010-09-02 | 2012-03-08 | Novartis Ag | Système de gel d'anticorps pour administration de médicament prolongée |
SG10201505624VA (en) | 2010-11-05 | 2015-09-29 | Novartis Ag | Methods of treating rheumatoid arthritis using il-17 antagonists |
DK2637690T3 (da) | 2010-11-11 | 2017-01-02 | Abbvie Biotechnology Ltd | Flydende ANTI-TNF-alpha-antistofformuleringer med høj koncentration |
JP2012158615A (ja) * | 2012-05-28 | 2012-08-23 | Kobayashi Pharmaceutical Co Ltd | 還元糖によるタンパク質変性を抑制する方法 |
US8613919B1 (en) | 2012-08-31 | 2013-12-24 | Bayer Healthcare, Llc | High concentration antibody and protein formulations |
US9592297B2 (en) | 2012-08-31 | 2017-03-14 | Bayer Healthcare Llc | Antibody and protein formulations |
WO2015181633A2 (fr) | 2014-04-11 | 2015-12-03 | Acerta Pharma B.V. | Procédés de blocage de la voie de signalisation cxcr4/sdf-1 à l'aide d'inhibiteurs de la tyrosine kinase de bruton |
WO2015185998A2 (fr) | 2014-04-11 | 2015-12-10 | Acerta Pharma B.V. | Procédés de blocage de la voie de signalisation des cxcr-4/sdf-1 à l'aide d'inhibiteurs de kinase x de moelle osseuse |
WO2016024227A1 (fr) | 2014-08-11 | 2016-02-18 | Acerta Pharma B.V. | Inhibiteurs de btk pour le traitement de tumeurs solides par modulation du micro-environnement tumoral |
WO2016055982A1 (fr) | 2014-10-10 | 2016-04-14 | Acerta Pharma B.V. | Composés quinoléine et quinazoline |
WO2016087994A1 (fr) | 2014-12-05 | 2016-06-09 | Acerta Pharma B.V. | Inhibiteurs de btk pour le traitement de tumeurs solides par modulation du micro-environnement tumoral |
EP4209499A1 (fr) | 2015-08-13 | 2023-07-12 | Amgen Inc. | Filtration sur profondeur chargée de protéines de liaison à l'antigène |
EP3865485A1 (fr) | 2015-11-06 | 2021-08-18 | Acerta Pharma B.V. | Inhibiteurs de la tyrosine kinase de bruton de type imidazopyrazine |
Family Cites Families (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2149304A (en) * | 1936-04-20 | 1939-03-07 | Sharp & Dohme Inc | Lyophilic biologically active substances |
SU700132A1 (ru) * | 1978-06-30 | 1979-11-30 | Томский Ордена Трудового Красного Знамени Научно-Исследовательский Институт Вакцин И Сывороток | Способ получени сухого препарата иммуноглобулина |
JPS57140724A (en) * | 1981-02-25 | 1982-08-31 | Green Cross Corp:The | Heat-treatment of aqueous solution containing cold insoluble globulin |
JPS58167518A (ja) * | 1982-03-29 | 1983-10-03 | Nippon Sekijiyuujishiya | ゼラチン誘導体添加静注用人免疫グロブリンの製造法 |
JPS6035263A (ja) * | 1983-08-05 | 1985-02-23 | Wako Pure Chem Ind Ltd | 不溶性担体に固定化された免疫活性物質の安定化法及び該物質を構成単位として含む生理活性物質測定用試薬 |
JPS60146833A (ja) * | 1984-01-10 | 1985-08-02 | Green Cross Corp:The | モノクロ−ナル抗体製剤 |
JP2565303B2 (ja) * | 1984-05-25 | 1996-12-18 | 三井東圧化学株式会社 | 緑膿菌感染症の予防治療剤 |
US4650772A (en) * | 1984-08-09 | 1987-03-17 | Abbott Laboratories | Monoclonal antibody stabilization |
JPH0669961B2 (ja) * | 1984-09-25 | 1994-09-07 | 株式会社ミドリ十字 | 免疫グロブリンの加熱処理方法 |
JPS61176532A (ja) * | 1985-01-30 | 1986-08-08 | Green Cross Corp:The | プラスミノ−ゲンアクチベ−タ−前駆体の安定化方法 |
JPH0825902B2 (ja) * | 1985-02-21 | 1996-03-13 | 株式会社ミドリ十字 | γ−グロブリンの加熱処理方法 |
JPH0825903B2 (ja) * | 1985-05-16 | 1996-03-13 | 株式会社ミドリ十字 | γ―グロブリン含有水溶液 |
JPS6178731A (ja) * | 1985-05-20 | 1986-04-22 | Green Cross Corp:The | 加熱処理免疫グロブリン製剤 |
DE3619565A1 (de) * | 1986-06-11 | 1987-12-17 | Behringwerke Ag | Verfahren zur herstellung einer pasteurisierten immunglobulinpraeparation |
JPS6388197A (ja) * | 1986-09-30 | 1988-04-19 | Tosoh Corp | モノクロナル抗体の安定化方法 |
AU591017B2 (en) * | 1986-12-15 | 1989-11-23 | Mitsui Toatsu Chemicals Inc. | Human monoclonal antibody and drug for prophylaxis and treatment of infectious diseases comprising same as effective ingredient |
ES2045027T3 (es) * | 1987-08-10 | 1994-01-16 | Miles Inc | Igm purificadas. |
JPH03504499A (ja) * | 1988-05-27 | 1991-10-03 | セントカー・インコーポレーテツド | 抗体試薬のための配合物 |
EP0465513A1 (fr) * | 1989-03-27 | 1992-01-15 | Centocor, Inc. | COMPOSITIONS SERVANT A STABILISER DES ANTICORPS D'IMMUNOGLOBULINE IgM |
JPH0384461A (ja) * | 1989-08-28 | 1991-04-10 | Green Cross Corp:The | 免疫学的凝集反応試薬及びその製法 |
JPH0911350A (ja) * | 1995-06-30 | 1997-01-14 | Olympus Optical Co Ltd | エネルギー硬化型樹脂を用いた光学素子の製造方法 |
-
1992
- 1992-02-27 JP JP4041015A patent/JPH0565233A/ja active Pending
- 1992-02-28 DE DE69225757T patent/DE69225757T2/de not_active Expired - Fee Related
- 1992-02-28 DK DK92906211T patent/DK0531539T3/da active
- 1992-02-28 CA CA002082169A patent/CA2082169A1/fr not_active Abandoned
- 1992-02-28 WO PCT/JP1992/000226 patent/WO1992015331A1/fr active IP Right Grant
- 1992-02-28 EP EP92906211A patent/EP0531539B1/fr not_active Expired - Lifetime
- 1992-02-28 DE DE69232617T patent/DE69232617T2/de not_active Expired - Fee Related
- 1992-02-28 EP EP97120255A patent/EP0841067B1/fr not_active Revoked
- 1992-02-28 DK DK97120255T patent/DK0841067T3/da active
- 1992-02-28 AU AU13375/92A patent/AU645187B2/en not_active Ceased
- 1992-11-04 FI FI924982A patent/FI924982A/fi not_active Application Discontinuation
- 1992-11-06 NO NO924279A patent/NO924279D0/no unknown
-
1994
- 1994-11-14 US US08/340,319 patent/US5908826A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP0531539A1 (fr) | 1993-03-17 |
EP0841067A1 (fr) | 1998-05-13 |
AU1337592A (en) | 1992-10-06 |
DE69232617D1 (de) | 2002-06-27 |
DE69232617T2 (de) | 2002-10-31 |
DK0841067T3 (da) | 2002-07-15 |
DE69225757T2 (de) | 1998-12-03 |
EP0531539B1 (fr) | 1998-06-03 |
FI924982A (fi) | 1992-11-04 |
CA2082169A1 (fr) | 1992-09-09 |
NO924279L (no) | 1992-11-06 |
US5908826A (en) | 1999-06-01 |
EP0531539A4 (fr) | 1995-04-05 |
EP0841067B1 (fr) | 2002-05-22 |
DK0531539T3 (da) | 1998-10-12 |
NO924279D0 (no) | 1992-11-06 |
JPH0565233A (ja) | 1993-03-19 |
WO1992015331A1 (fr) | 1992-09-17 |
AU645187B2 (en) | 1994-01-06 |
DE69225757D1 (de) | 1998-07-09 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD | Application lapsed |