FI922827A - Imidazodiazepiner - Google Patents
Imidazodiazepiner Download PDFInfo
- Publication number
- FI922827A FI922827A FI922827A FI922827A FI922827A FI 922827 A FI922827 A FI 922827A FI 922827 A FI922827 A FI 922827A FI 922827 A FI922827 A FI 922827A FI 922827 A FI922827 A FI 922827A
- Authority
- FI
- Finland
- Prior art keywords
- imidazodiazepiner
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D495/14—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Anesthesiology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH179191 | 1991-06-17 | ||
| CH114092 | 1992-04-08 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FI922827A0 FI922827A0 (fi) | 1992-06-17 |
| FI922827A true FI922827A (fi) | 1992-12-18 |
Family
ID=25686778
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI922827A FI922827A (fi) | 1991-06-17 | 1992-06-17 | Imidazodiazepiner |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US5387585A (pl) |
| EP (1) | EP0519307A3 (pl) |
| JP (1) | JPH078869B2 (pl) |
| KR (1) | KR930000517A (pl) |
| AU (1) | AU655472B2 (pl) |
| CA (1) | CA2069382A1 (pl) |
| CZ (1) | CZ185092A3 (pl) |
| FI (1) | FI922827A (pl) |
| HU (1) | HU9201929D0 (pl) |
| IE (1) | IE921945A1 (pl) |
| IL (1) | IL102175A0 (pl) |
| IS (1) | IS3878A (pl) |
| NO (1) | NO922367L (pl) |
| NZ (1) | NZ243091A (pl) |
| TW (1) | TW201311B (pl) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW349100B (en) * | 1994-11-11 | 1999-01-01 | Hoffmann La Roche | Oxazolyl- and thiazolylimidazo-benzo- and thienodiazepines |
| JPH10298078A (ja) * | 1997-05-06 | 1998-11-10 | Mitsubishi Chem Corp | 抗不安薬 |
| TWI239333B (en) * | 2000-11-16 | 2005-09-11 | Hoffmann La Roche | Benzodiazepine derivatives as GABA A receptor modulators |
| US6686352B2 (en) * | 2001-05-18 | 2004-02-03 | Hoffmann-La Roche Inc. | Substituted imidazo [1,5-a] pyrimido [5,4-d] [1] benzazepine derivatives |
| WO2002100341A2 (en) * | 2001-06-12 | 2002-12-19 | Wellstat Therapeutics Corporation | Compounds for the treatment of metabolic disorders |
| RU2007112675A (ru) * | 2004-10-12 | 2008-11-20 | Ф.Хоффманн-Ля Рош Аг (Ch) | ПРОИЗВОДНЫЕ ИМИДАЗО[1,5-a]ТРИАЗОЛО[1,5-d]БЕНЗОДИАЗЕПИНА ДЛЯ ЛЕЧЕНИЯ КОГНИТИВНЫХ РАССТРОЙСТВ |
| JP4783375B2 (ja) | 2004-10-20 | 2011-09-28 | エフ．ホフマン−ラ ロシュ アーゲー | イミダゾベンゾジゼピン誘導体 |
| WO2006045429A1 (en) * | 2004-10-20 | 2006-05-04 | F. Hoffmann-La Roche Ag | Halogen substituted benzodiazepine derivatives |
| JP4783380B2 (ja) | 2004-12-14 | 2011-09-28 | エフ．ホフマン−ラ ロシュ アーゲー | Ｇａｂａレセプタ調節物質としての四環系イミダゾ−ベンゾジアゼピン類 |
| BRPI0617204A2 (pt) * | 2005-10-11 | 2011-07-19 | Hoffmann La Roche | derivados de imidazo benzodiazepina |
| AU2009300357B2 (en) * | 2008-09-23 | 2014-07-03 | The Johns Hopkins University | Fused diimidazodiazepine compounds and methods of use and manufacture thereof |
| US9322831B2 (en) | 2008-09-23 | 2016-04-26 | The Johns Hopkins University | DDX3 as a biomarker for cancer and methods related thereto |
| AU2014240289B2 (en) * | 2008-09-23 | 2015-12-03 | The Johns Hopkins University | Fused diimidazodiazepine compounds and methods of use and manufacture thereof |
| US9145372B2 (en) | 2010-11-15 | 2015-09-29 | Agenebio, Inc. | Pyridazine derivatives, compositions and methods for treating cognitive impairment |
| MX365218B (es) | 2013-09-06 | 2019-05-27 | Aurigene Discovery Tech Ltd | Derivados de 1,2,4-oxadiazol como inmunomoduladores. |
| CA3123897C (en) | 2013-12-20 | 2024-02-06 | Agenebio, Inc. | Benzodiazepine derivatives, compositions, and methods for treating cognitive impairment |
| KR20170123317A (ko) * | 2015-03-10 | 2017-11-07 | 오리진 디스커버리 테크놀로지스 리미티드 | 면역조절제로서의 3-치환된-1,2,4-옥사다이아졸 및 티아다이아졸 화합물 |
| CN107427477B (zh) | 2015-03-10 | 2021-11-26 | 奥瑞基尼探索技术有限公司 | 作为免疫调节剂的1,2,4-噁二唑和噻二唑化合物 |
| CA2990004C (en) * | 2015-06-19 | 2024-04-23 | Agenebio, Inc. | Benzodiazepine derivatives, compositions, and methods for treating cognitive impairment |
| BR112018012914B1 (pt) | 2015-12-22 | 2023-04-18 | SHY Therapeutics LLC | Composto, uso de um composto e composição farmacêutica |
| US11505555B2 (en) | 2016-12-19 | 2022-11-22 | Agenebio, Inc. | Benzodiazepine derivatives, compositions, and methods for treating cognitive impairment |
| US20180170941A1 (en) * | 2016-12-19 | 2018-06-21 | Agenebio, Inc. | Benzodiazepine derivatives, compositions, and methods for treating cognitive impairment |
| IL271230B1 (en) | 2017-06-21 | 2024-02-01 | SHY Therapeutics LLC | Compounds interacting with the RAS superfamily for the treatment of cancer, inflammation, RAS pathology and fibrotic diseases |
| WO2019061324A1 (en) | 2017-09-29 | 2019-04-04 | Curis Inc. | CRYSTALLINE FORMS OF IMMUNOMODULATORS |
| EP3694841A1 (en) | 2017-10-11 | 2020-08-19 | Aurigene Discovery Technologies Limited | Crystalline forms of 3-substituted 1,2,4-oxadiazole |
| KR20200083503A (ko) | 2017-11-03 | 2020-07-08 | 오리진 디스커버리 테크놀로지스 리미티드 | Tim-3 경로와 pd-1 경로의 이중 저해제 |
| CN111386128A (zh) | 2017-11-06 | 2020-07-07 | 奥瑞基尼探索技术有限公司 | 用于免疫调节的联合疗法 |
| JP2021528427A (ja) | 2018-06-19 | 2021-10-21 | エージンバイオ， インコーポレイテッド | 認知障害を処置するためのベンゾジアゼピン誘導体、組成物および方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1143728A (en) * | 1979-10-04 | 1983-03-29 | Max Gerecke | Imidazodiazepine derivatives |
| FI850191L (fi) * | 1984-01-19 | 1985-07-20 | Hoffmann La Roche | Imidazodiazepinderivat. |
| US4897392A (en) * | 1989-07-03 | 1990-01-30 | Hoechst-Roussel Pharmaceuticals, Inc. | 4H-indolo(1,2-d)(1,2,4)triazolo(4,3-A)(1,4)benzodiazepines |
| DK443589D0 (da) * | 1989-09-08 | 1989-09-08 | Ferrosan As | Heterocykliske forbindelser, deres fremstilling og anvendelse |
| DK41191D0 (da) * | 1991-03-07 | 1991-03-07 | Novo Nordisk As | Heterocycliske forbindelser, deres fremstilling og anvendelse |
-
1992
- 1992-05-15 TW TW081103807A patent/TW201311B/zh active
- 1992-05-25 CA CA002069382A patent/CA2069382A1/en not_active Abandoned
- 1992-06-10 HU HU9201929A patent/HU9201929D0/hu unknown
- 1992-06-10 EP EP19920109745 patent/EP0519307A3/de not_active Withdrawn
- 1992-06-10 NZ NZ243091A patent/NZ243091A/en unknown
- 1992-06-11 IL IL102175A patent/IL102175A0/xx unknown
- 1992-06-12 AU AU18234/92A patent/AU655472B2/en not_active Ceased
- 1992-06-12 JP JP4179406A patent/JPH078869B2/ja not_active Expired - Lifetime
- 1992-06-12 IS IS3878A patent/IS3878A/is unknown
- 1992-06-16 CZ CS921850A patent/CZ185092A3/cs unknown
- 1992-06-16 KR KR1019920010394A patent/KR930000517A/ko not_active Application Discontinuation
- 1992-06-16 NO NO92922367A patent/NO922367L/no unknown
- 1992-06-17 FI FI922827A patent/FI922827A/fi not_active Application Discontinuation
- 1992-07-01 IE IE194592A patent/IE921945A1/en not_active Application Discontinuation
-
1993
- 1993-11-15 US US08/153,234 patent/US5387585A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| IE921945A1 (en) | 1992-12-30 |
| KR930000517A (ko) | 1993-01-15 |
| NO922367D0 (no) | 1992-06-16 |
| IL102175A0 (en) | 1993-01-14 |
| NZ243091A (en) | 1994-11-25 |
| AU1823492A (en) | 1992-12-24 |
| US5387585A (en) | 1995-02-07 |
| AU655472B2 (en) | 1994-12-22 |
| JPH05202051A (ja) | 1993-08-10 |
| EP0519307A3 (en) | 1993-04-21 |
| JPH078869B2 (ja) | 1995-02-01 |
| EP0519307A2 (de) | 1992-12-23 |
| NO922367L (no) | 1992-12-18 |
| CZ185092A3 (en) | 1993-12-15 |
| FI922827A0 (fi) | 1992-06-17 |
| IS3878A (is) | 1992-12-18 |
| CA2069382A1 (en) | 1992-12-18 |
| TW201311B (pl) | 1993-03-01 |
| HU9201929D0 (en) | 1992-08-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD | Application lapsed |