FI912375A - Indolderivat. - Google Patents

Indolderivat. Download PDF

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Publication number
FI912375A
FI912375A FI912375A FI912375A FI912375A FI 912375 A FI912375 A FI 912375A FI 912375 A FI912375 A FI 912375A FI 912375 A FI912375 A FI 912375A FI 912375 A FI912375 A FI 912375A
Authority
FI
Finland
Prior art keywords
chem
alkyl
hydrogen
alkylene
lower alkylene
Prior art date
Application number
FI912375A
Other languages
English (en)
Finnish (fi)
Other versions
FI912375A0 (fi
Inventor
Satoshi Okada
Kozo Sawada
Natsuko Kayakiri
Yuki Saitoh
Hirokazu Tanaka
Masashi Hashimoto
Original Assignee
Fujisawa Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujisawa Pharmaceutical Co filed Critical Fujisawa Pharmaceutical Co
Publication of FI912375A0 publication Critical patent/FI912375A0/fi
Publication of FI912375A publication Critical patent/FI912375A/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an alkyl or cycloalkyl radical attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/12—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Dermatology (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI912375A 1990-05-21 1991-05-16 Indolderivat. FI912375A (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB909011335A GB9011335D0 (en) 1990-05-21 1990-05-21 Indolebutyric acid derivatives and process for preparation thereof

Publications (2)

Publication Number Publication Date
FI912375A0 FI912375A0 (fi) 1991-05-16
FI912375A true FI912375A (fi) 1991-11-22

Family

ID=10676312

Family Applications (1)

Application Number Title Priority Date Filing Date
FI912375A FI912375A (fi) 1990-05-21 1991-05-16 Indolderivat.

Country Status (18)

Country Link
EP (1) EP0458207B1 (fr)
JP (1) JPH0678307B2 (fr)
KR (1) KR910019975A (fr)
CN (1) CN1030701C (fr)
AT (1) ATE150747T1 (fr)
AU (1) AU645560B2 (fr)
CA (1) CA2042905A1 (fr)
DE (1) DE69125308T2 (fr)
DK (1) DK0458207T3 (fr)
FI (1) FI912375A (fr)
GB (1) GB9011335D0 (fr)
GR (1) GR3022953T3 (fr)
HU (2) HUT60471A (fr)
IE (1) IE911641A1 (fr)
NO (1) NO175475C (fr)
PT (1) PT97717B (fr)
RU (1) RU2045518C1 (fr)
ZA (1) ZA913457B (fr)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5334716A (en) * 1991-06-17 1994-08-02 Fujisawa Pharmaceutical Co., Ltd. Heterocyclic derivatives
RU2120942C1 (ru) * 1991-06-17 1998-10-27 Фудзисава Фармасьютикал Ко., Лтд. ПРОИЗВОДНЫЕ ИНДОЛИЗИНА, СПОСОБ ИХ ПОЛУЧЕНИЯ, ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ, СПОСОБ ИНГИБИРОВАНИЯ ТЕСТОСТЕРОН 5α-РЕДУКТАЗЫ
GB9115951D0 (en) * 1991-07-24 1991-09-11 Pfizer Ltd Indoles
JPH07501790A (ja) * 1991-09-11 1995-02-23 藤沢薬品工業株式会社 ５−アルファレダクターゼ阻害剤としてのインドール誘導体
GB9127531D0 (en) * 1991-12-31 1992-02-19 Fujisawa Pharmaceutical Co Heterocyclic compound
GB9204024D0 (en) * 1992-02-25 1992-04-08 Fujisawa Pharmaceutical Co Indole derivatives
GB9204365D0 (en) * 1992-02-28 1992-04-08 Pfizer Ltd Indoles
WO1993023053A1 (fr) * 1992-05-21 1993-11-25 Endorecherche Inc. INHIBITEURS D'ACTIVITE DE LA TESTOSTERONE 5α-REDUCTASE
GB9302577D0 (en) * 1993-02-10 1993-03-24 Fujisawa Pharmaceutical Co Indole derivatives
EP0648208A1 (fr) * 1993-04-05 1995-04-19 Fujisawa Pharmaceutical Co., Ltd. Derives de l'indole utilises en tant qu'inhibiteurs de la 5-alpha-reductase de testosterone
GB9310092D0 (en) * 1993-05-17 1993-06-30 Fujisawa Pharmaceutical Co Indole derivatives
IL109728A0 (en) * 1993-05-28 1994-08-26 Pfizer Res & Dev Indoles
GB9317096D0 (en) * 1993-08-17 1993-09-29 Pfizer Ltd Indoles
PT753511E (pt) * 1994-03-30 2001-11-30 Zeria Pharm Co Ltd Derivados de acido 4-indol-1-butirico, sua preparacao e utilizacao como inibidores dos receptores alfa-1-adrenergicos e das 5-alfa-redutases da testosterona
GB9409583D0 (en) * 1994-05-13 1994-07-06 Pfizer Ltd Indoles
KR100584650B1 (ko) 1998-03-31 2006-05-30 디 인스티튜트스 포 파마슈티컬 디스커버리, 엘엘씨 치환된 인돌알칸산
WO2003020311A1 (fr) * 2001-08-28 2003-03-13 Fujisawa Pharmaceutical Co., Ltd. Remedes contre les maladies de la peau
MXPA05011841A (es) 2003-05-09 2006-01-26 Hoffmann La Roche Metil-indoles y metil-pirrolopiridinas como agonistas adrenergicos de alfa-1.
TW201329025A (zh) * 2011-11-01 2013-07-16 Astex Therapeutics Ltd 醫藥化合物
CA3095934A1 (fr) 2018-04-05 2019-10-10 Beth Israel Deaconess Medical Center, Inc. Modulateurs du recepteur d'hydrocarbure aryle et utilisations associees

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR7337M (fr) * 1968-01-11 1969-10-13
PH23498A (en) * 1984-08-06 1989-08-16 Sterling Drug Inc 3-carbonyl-1-aminoalkyl-1h-indoles,composition and use thereof

Also Published As

Publication number Publication date
HU911681D0 (en) 1991-11-28
FI912375A0 (fi) 1991-05-16
NO911938L (no) 1991-11-22
CA2042905A1 (fr) 1991-11-22
CN1030701C (zh) 1996-01-17
DE69125308D1 (de) 1997-04-30
DE69125308T2 (de) 1997-07-10
HU211637A9 (en) 1995-12-28
EP0458207A3 (en) 1992-03-25
CN1056685A (zh) 1991-12-04
NO175475C (no) 1994-10-19
PT97717B (pt) 1998-08-31
GB9011335D0 (en) 1990-07-11
GR3022953T3 (en) 1997-06-30
NO175475B (no) 1994-07-11
ZA913457B (en) 1992-02-26
KR910019975A (ko) 1991-12-19
EP0458207B1 (fr) 1997-03-26
EP0458207A2 (fr) 1991-11-27
JPH0678307B2 (ja) 1994-10-05
HUT60471A (en) 1992-09-28
JPH04244061A (ja) 1992-09-01
IE911641A1 (en) 1991-12-04
PT97717A (pt) 1992-02-28
NO911938D0 (no) 1991-05-16
RU2045518C1 (ru) 1995-10-10
DK0458207T3 (fr) 1997-04-21
ATE150747T1 (de) 1997-04-15
AU7711691A (en) 1991-11-21
AU645560B2 (en) 1994-01-20

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