FI905124A0 - Förfarande för framställning av pyrimidiner - Google Patents

Förfarande för framställning av pyrimidiner

Info

Publication number
FI905124A0
FI905124A0 FI905124A FI905124A FI905124A0 FI 905124 A0 FI905124 A0 FI 905124A0 FI 905124 A FI905124 A FI 905124A FI 905124 A FI905124 A FI 905124A FI 905124 A0 FI905124 A0 FI 905124A0
Authority
FI
Finland
Prior art keywords
pyrimidines
preparation
Prior art date
Application number
FI905124A
Other languages
English (en)
Finnish (fi)
Other versions
FI93957C (sv
FI93957B (sv
Inventor
Peter Herold
Peter Buehlmayer
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of FI905124A0 publication Critical patent/FI905124A0/sv
Application granted granted Critical
Publication of FI93957B publication Critical patent/FI93957B/sv
Publication of FI93957C publication Critical patent/FI93957C/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/26—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI905124A 1989-10-19 1990-10-17 Förfarande för framställning av pyrimidiner FI93957C (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH379989 1989-10-19
CH379989 1989-10-19

Publications (3)

Publication Number Publication Date
FI905124A0 true FI905124A0 (sv) 1990-10-17
FI93957B FI93957B (sv) 1995-03-15
FI93957C FI93957C (sv) 1995-06-26

Family

ID=4263704

Family Applications (1)

Application Number Title Priority Date Filing Date
FI905124A FI93957C (sv) 1989-10-19 1990-10-17 Förfarande för framställning av pyrimidiner

Country Status (14)

Country Link
EP (1) EP0424317A3 (sv)
JP (1) JPH03133964A (sv)
KR (1) KR910007889A (sv)
AU (1) AU638496B2 (sv)
CA (1) CA2027839A1 (sv)
FI (1) FI93957C (sv)
HU (1) HUT55383A (sv)
IE (1) IE903749A1 (sv)
IL (1) IL96009A0 (sv)
MX (1) MX22877A (sv)
NO (1) NO176758C (sv)
NZ (1) NZ235726A (sv)
PT (1) PT95626A (sv)
ZA (1) ZA908344B (sv)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0522038A4 (en) * 1990-03-30 1993-05-26 Merck & Co. Inc. Substituted pyrimidines, pyrimidinones and pyridopyrimidines
US5324729A (en) * 1990-03-30 1994-06-28 Merck & Co., Inc. Substituted pyrimidines, pyrimidinones and pyridopyrimidines
AU653734B2 (en) * 1990-06-19 1994-10-13 Meiji Seika Kabushiki Kaisha Substituted 4-biphenylmethoxypyridine derivatives
IL99246A0 (en) * 1990-09-10 1992-07-15 Abbott Lab Angiotensin ii receptor antagonists and pharmaceutical compositions containing them
US5250548A (en) * 1990-09-10 1993-10-05 Abbott Laboratories Angiotensin II receptor antagonists
FR2672892B1 (fr) * 1991-02-20 1994-01-14 Synthelabo Derives de 4-pyrimidinones, leur preparation et leur application en therapeutique.
US5472967A (en) * 1991-02-20 1995-12-05 Synthelabo 4-pyrimidinone derivatives their preparation and their application in therapy
DE4110019C2 (de) * 1991-03-27 2000-04-13 Merck Patent Gmbh Imidazopyridine, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen
IL101860A0 (en) * 1991-05-31 1992-12-30 Ici Plc Heterocyclic derivatives
IT1250749B (it) * 1991-08-02 1995-04-21 Luso Farmaco Inst Composti eterociclici ad attivita' a ii antagonista
US5234936A (en) * 1991-10-24 1993-08-10 American Home Products Corporation Pyrimidocycloalkanes as a ii antagonists
US5236925A (en) * 1991-10-24 1993-08-17 American Home Products Corporation Fused pyrimidines as angiotensin II antagonists
US5256781A (en) * 1991-10-24 1993-10-26 American Home Products Corporation Substituted quinazolines as angiotensin II antagonists
DE4221583A1 (de) 1991-11-12 1993-05-13 Bayer Ag Substituierte biphenylpyridone
GB9125842D0 (en) * 1991-12-04 1992-02-05 Ici Plc Heterocyclic derivatives
US5225408A (en) * 1991-12-20 1993-07-06 E. R. Squibb & Sons, Inc. Biphenyl oxadiazinone angiotensin II inhibitors
ZA931062B (en) * 1992-02-17 1993-08-17 Ciba Geigy Compositions for the treatment of glaucoma.
US5378704A (en) * 1992-04-15 1995-01-03 E. R. Squibb & Sons, Inc. Non-peptidic angiotensin-II-receptor-antagonists
US5236916A (en) * 1992-05-26 1993-08-17 E. R. Squibb & Sons, Inc. Oxadiazinone substituted indole and benzimidazole derivatives
TW348175B (en) * 1993-01-06 1998-12-21 Hoechst Ag Process for the preparation of biphenyl derivatives
US6518424B1 (en) 1998-11-12 2003-02-11 Elan Pharmaceuticals, Inc. Substituted pyrimidine compositions and methods of use
SE9903028D0 (sv) 1999-08-27 1999-08-27 Astra Ab New use
JP4880473B2 (ja) * 2004-10-08 2012-02-22 壽製薬株式会社 ホスホン酸誘導体及び血中の高リン酸が関与する疾患の治療剤
CA2604797C (en) * 2005-04-12 2013-05-28 Vicore Pharma Ab New tricyclic angiotensin ii agonists
ES2393885T7 (es) 2007-06-04 2014-01-30 Synergy Pharmaceuticals Inc. Agonistas de la guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros trastornos
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
ES2522968T3 (es) 2008-06-04 2014-11-19 Synergy Pharmaceuticals Inc. Agonistas de guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros trastornos
AU2009270833B2 (en) 2008-07-16 2015-02-19 Bausch Health Ireland Limited Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders
WO2011105099A1 (ja) * 2010-02-25 2011-09-01 興和株式会社 新規な４－アルコキシピリミジン構造を有する化合物及びこれを含有する医薬
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
CA2905435A1 (en) 2013-03-15 2014-09-25 Synergy Pharmaceuticals Inc. Compositions useful for the treatment of gastrointestinal disorders
JP2016514671A (ja) 2013-03-15 2016-05-23 シナジー ファーマシューティカルズ インコーポレイテッド グアニル酸シクラーゼのアゴニストおよびその使用
US10011637B2 (en) 2013-06-05 2018-07-03 Synergy Pharmaceuticals, Inc. Ultra-pure agonists of guanylate cyclase C, method of making and using same
WO2022057858A1 (zh) * 2020-09-17 2022-03-24 浙江海正药业股份有限公司 酰胺膦氧类衍生物及其制备方法和用途

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1334092C (en) * 1986-07-11 1995-01-24 David John Carini Angiotensin ii receptor blocking imidazoles

Also Published As

Publication number Publication date
HU906501D0 (en) 1991-04-29
EP0424317A2 (de) 1991-04-24
NO176758C (no) 1995-05-24
PT95626A (pt) 1991-09-13
NO904511D0 (no) 1990-10-18
HUT55383A (en) 1991-05-28
FI93957C (sv) 1995-06-26
IE903749A1 (en) 1991-04-24
JPH03133964A (ja) 1991-06-07
IL96009A0 (en) 1991-07-18
CA2027839A1 (en) 1991-04-20
AU638496B2 (en) 1993-07-01
FI93957B (sv) 1995-03-15
AU6468090A (en) 1991-04-26
KR910007889A (ko) 1991-05-30
NO904511L (no) 1991-04-22
NO176758B (no) 1995-02-13
ZA908344B (en) 1991-06-26
MX22877A (es) 1993-12-01
EP0424317A3 (en) 1991-09-25
NZ235726A (en) 1993-09-27

Similar Documents

Publication Publication Date Title
FI905124A0 (sv) Förfarande för framställning av pyrimidiner
TR25002A (tr) Kristalik natrinyumsilikatlarin hazirlanis yöntemi
BG93508A (bg) Производни на пиримидина
FI945441A0 (sv) Nytt förfarande för framställning av 7beta-substituerad-4-aza-5alfa-androstan-3-oner
FI92403B (sv) Förfarande för framställning av Cefodizim-dinatrium
FI95036B (sv) Förfarande för framställning av tieno-triazolo-diazepinderivat
FI91961C (sv) Förfarande för tillverkning av (S)- -etyl-2-oxo-1-pyrrolidinacetamid
ES2013216A4 (es) Proceso para la preparacion de n - fosfonometilglicina
FI920468A (fi) Medicinskt droppglas med kroppsviktsskala
IT9067657A0 (it) Procedimento per la preparazione di alfa-alchil-lattoni.
DK28788A (da) Fremgangsmaade til fremstilling af alkansulfonamider
DK573888A (da) Fremgangsmaade til fremstilling af paramunitetsinducere
DK0388620T3 (da) Fremgangsmåde til fremstilling af o-carboxy-pyridyl- og o-carboxyquinolylimidazolinoner
DK0409321T3 (da) Fremgangsmåde til fremstilling af delta-lactoner
IT8822524A0 (it) Procedimento di preparazione di 6-ossopenicillanati
FI901358A0 (sv) Förfarande för framställning av fluorfenoler
FI93363C (sv) Nytt förfarande för framställning av 2-diazo-3-trisubstituerade silyloxi-3-butenoater
IT9022506A0 (it) Procedimento per la preparazione di un intermedio
FI943660A0 (sv) Framställningsförfarande för 3-karbonylandrostadien-17-karboxamider
IT9067138A1 (it) Procedimento per la preparazione di alfa-alchil lattoni.
IT8848410A0 (it) Procedimento per la preparazione di calcestruzzo proiettato
DK0381622T3 (da) Fremgangsmåde til fremstilling af dihalogenbutyraldehyder
DK0381353T3 (da) Fremgangsmåde til fremstilling af polyalkyltetrahydronaphthalener
IT218971Z2 (it) Doga per la realizzazione di strutture di reti-letto
IT9021514A0 (it) Procedimento per la preparazione di l-alfa-glicerilfosforilcolina

Legal Events

Date Code Title Description
FG Patent granted

Owner name: CIBA-GEIGY AG

BB Publication of examined application
MM Patent lapsed
MM Patent lapsed

Owner name: CIBA-GEIGY AG