FI884087L - Foerfarande foer framstaellning av metylenderivat av androsta-1,4-dien-3,17-dion. - Google Patents

Foerfarande foer framstaellning av metylenderivat av androsta-1,4-dien-3,17-dion. Download PDF

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Publication number
FI884087L
FI884087L FI884087A FI884087A FI884087L FI 884087 L FI884087 L FI 884087L FI 884087 A FI884087 A FI 884087A FI 884087 A FI884087 A FI 884087A FI 884087 L FI884087 L FI 884087L
Authority
FI
Finland
Prior art keywords
methylenderivat
androsta
dion
dien
foerfarande foer
Prior art date
Application number
FI884087A
Other languages
English (en)
Finnish (fi)
Other versions
FI884087A0 (fi
FI884087A7 (fi
Inventor
Antonio Longo
Paolo Lombardi
Original Assignee
Erba Carlo Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Carlo Spa filed Critical Erba Carlo Spa
Publication of FI884087A0 publication Critical patent/FI884087A0/fi
Publication of FI884087A7 publication Critical patent/FI884087A7/fi
Publication of FI884087L publication Critical patent/FI884087L/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003Androstane derivatives
    • C07J1/0011Androstane derivatives substituted in position 17 by a keto group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003Androstane derivatives
    • C07J1/0018Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa
    • C07J1/0022Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J75/00Processes for the preparation of steroids in general

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
  • Saccharide Compounds (AREA)
FI884087A 1987-09-11 1988-09-06 Foerfarande foer framstaellning av metylenderivat av androsta-1,4-dien-3,17-dion. FI884087L (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB878721383A GB8721383D0 (en) 1987-09-11 1987-09-11 Preparation of methylene derivatives

Publications (3)

Publication Number Publication Date
FI884087A0 FI884087A0 (fi) 1988-09-06
FI884087A7 FI884087A7 (fi) 1989-03-12
FI884087L true FI884087L (fi) 1989-03-12

Family

ID=10623618

Family Applications (1)

Application Number Title Priority Date Filing Date
FI884087A FI884087L (fi) 1987-09-11 1988-09-06 Foerfarande foer framstaellning av metylenderivat av androsta-1,4-dien-3,17-dion.

Country Status (16)

Country Link
US (1) US4876045A (cs)
EP (1) EP0307134B1 (cs)
JP (1) JP2791046B2 (cs)
KR (1) KR970005315B1 (cs)
AT (1) ATE78488T1 (cs)
AU (1) AU602608B2 (cs)
CA (1) CA1316914C (cs)
DE (1) DE3872995T2 (cs)
ES (1) ES2051858T3 (cs)
FI (1) FI884087L (cs)
GB (1) GB8721383D0 (cs)
GR (1) GR3005296T3 (cs)
HU (1) HU199156B (cs)
IL (1) IL87657A (cs)
SU (1) SU1681731A3 (cs)
UA (1) UA6044A1 (cs)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9201224D0 (en) * 1992-01-21 1992-03-11 Erba Carlo Spa Difluoromethylenandrostenone derivatives and process for their preparation
WO2001004342A1 (en) * 1999-07-07 2001-01-18 Pharmacia & Upjohn Company Process to prepare exemestane
CN1304413C (zh) * 2002-10-24 2007-03-14 上海华拓医药科技发展有限公司 一种抗癌药物依西美坦制备方法
ATE548375T1 (de) * 2004-01-16 2012-03-15 Cedarburg Pharmaceuticals Inc Exemestan und zwischenprodukte davon und verfahren zu dessen herstellung
US10174070B2 (en) 2005-09-30 2019-01-08 Endece Llc 6-substituted estradiol derivatives and methods of use
US20070225354A1 (en) * 2006-03-21 2007-09-27 Eric Marchewitz Use of dihydrolipoamide for enhancing physical performance
US7569719B1 (en) * 2006-10-25 2009-08-04 Loctite (R&D) Limited Method of preparing electron deficient olefins
US20080275259A1 (en) 2007-05-04 2008-11-06 Scinopharm Taiwan, Ltd Process for preparing aromatase inhibitors
EP2170328A2 (en) * 2007-06-25 2010-04-07 ScinoPharm Taiwan, Ltd. Crystalline polymorph of exemestane
KR101579625B1 (ko) * 2007-06-25 2015-12-22 시노팜 타이완 리미티드 7-에틸-10-히드록시캄토테신의 결정성 다형체
US8686105B2 (en) 2007-10-24 2014-04-01 Henkel IP & Holding GmbH Adhesive systems using imines and salts thereof, precursors to electron deficient olefins and coreactants therefor
CA2703596A1 (en) * 2007-10-24 2009-04-30 Loctite (R&D) Limited Activated methylene reagents and curable compositions prepared therefrom
JP5639892B2 (ja) * 2007-10-24 2014-12-10 ヘンケル アイルランド リミテッド 電子欠損オレフィン
US7973119B1 (en) 2007-10-24 2011-07-05 Loctite (R&D) Limited Adhesive systems using imines and salts thereof and precursurs to electron deficient olefins
US8053589B1 (en) * 2007-10-24 2011-11-08 Henkel Ireland Limited Imines and methods of preparing electron deficient olefins using such novel imines
US8399698B1 (en) 2008-10-24 2013-03-19 Henkel Ireland Limited Substituted activated methylene reagents and methods of using such reagents to form electron deficient olefins
US10196471B1 (en) 2008-10-24 2019-02-05 Henkel IP & Holding GmbH Curable composition having an electron deficient olefin
WO2010127297A1 (en) 2009-05-01 2010-11-04 Parviz Gharagozloo Treating male infertility secondary to sperm oxidative stress
DK2616477T3 (en) 2010-09-14 2017-02-20 Endece Llc 6-substituted demethyl estradiol derivatives as agonists of the type ER-BETA
CN105085599A (zh) * 2014-05-16 2015-11-25 绍兴文理学院 一种依西美坦中间体17,17-乙二氧基-6-亚甲基雄甾-1,4-二烯-3-酮及其制备方法和应用
CN105294807A (zh) * 2014-06-26 2016-02-03 浙江医药股份有限公司新昌制药厂 一种依西美坦中间体肟化合物及其制备方法和应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3004508C2 (de) * 1980-02-05 1981-12-10 Schering Ag Berlin Und Bergkamen, 1000 Berlin Verfahren zur Herstellung von 6-Methylensteroiden
GB8517360D0 (en) * 1985-07-09 1985-08-14 Erba Farmitalia Substituted androsta-1,4-diene-3,17-diones

Also Published As

Publication number Publication date
KR970005315B1 (ko) 1997-04-15
CA1316914C (en) 1993-04-27
DE3872995D1 (de) 1992-08-27
JPH01104095A (ja) 1989-04-21
US4876045A (en) 1989-10-24
EP0307134B1 (en) 1992-07-22
ES2051858T3 (es) 1994-07-01
AU602608B2 (en) 1990-10-18
KR890005141A (ko) 1989-05-13
EP0307134A1 (en) 1989-03-15
IL87657A (en) 1993-02-21
HUT48273A (en) 1989-05-29
SU1681731A3 (ru) 1991-09-30
IL87657A0 (en) 1989-02-28
DE3872995T2 (de) 1992-12-10
FI884087A0 (fi) 1988-09-06
UA6044A1 (uk) 1994-12-29
ATE78488T1 (de) 1992-08-15
JP2791046B2 (ja) 1998-08-27
FI884087A7 (fi) 1989-03-12
GB8721383D0 (en) 1987-10-21
AU2198088A (en) 1989-03-16
GR3005296T3 (cs) 1993-05-24
HU199156B (en) 1990-01-29

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Legal Events

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FD Application lapsed

Owner name: FARMITALIA CARLO ERBA S.R.L