FI88359B - Foerfarande foer framstaellning av en kardiovaskulaer komposition att anvaendas lokalt - Google Patents

Foerfarande foer framstaellning av en kardiovaskulaer komposition att anvaendas lokalt Download PDF

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Publication number
FI88359B
FI88359B FI871695A FI871695A FI88359B FI 88359 B FI88359 B FI 88359B FI 871695 A FI871695 A FI 871695A FI 871695 A FI871695 A FI 871695A FI 88359 B FI88359 B FI 88359B
Authority
FI
Finland
Prior art keywords
composition
acid
carboxylic acid
kardiovaskulaer
locally
Prior art date
Application number
FI871695A
Other languages
English (en)
Finnish (fi)
Other versions
FI871695A0 (fi
FI871695A (fi
FI88359C (sv
Inventor
Walter Fries
Original Assignee
Mack Chem Pharm
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mack Chem Pharm filed Critical Mack Chem Pharm
Publication of FI871695A0 publication Critical patent/FI871695A0/fi
Publication of FI871695A publication Critical patent/FI871695A/fi
Application granted granted Critical
Publication of FI88359B publication Critical patent/FI88359B/fi
Publication of FI88359C publication Critical patent/FI88359C/sv

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Organic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Urology & Nephrology (AREA)
  • Emergency Medicine (AREA)
  • Vascular Medicine (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Polishing Bodies And Polishing Tools (AREA)
  • Wrappers (AREA)
  • Cosmetics (AREA)

Claims (4)

1. Förfarande för framställning av en förbättrad farmaceutisk kardiovaskulär komposition att användas lo- 5 kait, väri soin essentiell aktiv lngrediens ingär en ester av salpetersyra, vilken effektivt utvidgar blodkärl, kännetecknat därav, att en för huden lämplig hydroxialkankolvätekarboxylsyra med tre till sex kolatomer blandas med den ifrägavarande nitroester innehällande kom- 10 positionen vid en koncentration pä ca 1 - 6 vikt-% av to-talkompositionen.
2. Förfarande enligt patentkravet 1, kännetecknat därav, att ifrägavarande blodkärlsutvidgan-de salpetersyraester, vilken används som essentiell aktiv 15 ingredies, är nitroglycerin, isosorbiddinitrat eller iso- sorbid-5-mononitrat.
3. Förfarande enligt patentkravet 1, kännetecknat därav, att hydroxialkankolvätekarboxylsyran är mjölksyra. 20
4. Förfarande enligt patentkravet 1, känne tecknat därav, att hydroxialkankolvätekarboxylsyran är citronsyra.
FI871695A 1986-04-18 1987-04-16 Förfarande för framställning av en kardiovaskulär komposition att anvä ndas lokalt FI88359C (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3613187 1986-04-18
DE19863613187 DE3613187A1 (de) 1986-04-18 1986-04-18 Verwendung einer carbonsaeure in zur topischen anwendung bestimmten pharmazeutischen zubereitungen

Publications (4)

Publication Number Publication Date
FI871695A0 FI871695A0 (fi) 1987-04-16
FI871695A FI871695A (fi) 1987-10-19
FI88359B true FI88359B (fi) 1993-01-29
FI88359C FI88359C (sv) 1993-05-10

Family

ID=6299028

Family Applications (1)

Application Number Title Priority Date Filing Date
FI871695A FI88359C (sv) 1986-04-18 1987-04-16 Förfarande för framställning av en kardiovaskulär komposition att anvä ndas lokalt

Country Status (10)

Country Link
EP (1) EP0241847B1 (sv)
JP (1) JPS62255418A (sv)
AT (1) ATE65396T1 (sv)
DE (2) DE3613187A1 (sv)
DK (1) DK192487A (sv)
ES (1) ES2037677T3 (sv)
FI (1) FI88359C (sv)
GR (1) GR3002381T3 (sv)
IE (1) IE59471B1 (sv)
PT (1) PT84694B (sv)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU199678B (en) * 1988-07-08 1990-03-28 Egyt Gyogyszervegyeszeti Gyar Process for producing aerosols containing nitroglicerol
DE4026072A1 (de) * 1990-08-17 1992-02-20 Sanol Arznei Schwarz Gmbh Nitroglycerinhaltiger, hydrophiler, waessriger pumpspray
JP5308794B2 (ja) 2007-12-11 2013-10-09 住友化学株式会社 噴流層装置を用いたポリオレフィン製造方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2924005C2 (de) * 1979-06-13 1984-07-05 Sanol Schwarz-Monheim Gmbh, 4019 Monheim Isosorbiddinitrat enthaltendes Mittel
EP0052404B1 (en) * 1980-11-19 1987-05-27 THE PROCTER & GAMBLE COMPANY Non-yellowing topical pharmaceutical composition
DE3325466A1 (de) * 1983-07-14 1985-01-24 Mack Chem Pharm Pharmazeutische zubereitung enthaltend isosorbiddinitrat

Also Published As

Publication number Publication date
FI871695A0 (fi) 1987-04-16
PT84694A (en) 1987-05-01
JPH0228578B2 (sv) 1990-06-25
EP0241847B1 (en) 1991-07-24
IE59471B1 (en) 1994-03-09
GR3002381T3 (en) 1992-12-30
DK192487A (da) 1987-10-19
JPS62255418A (ja) 1987-11-07
EP0241847A1 (en) 1987-10-21
ES2037677T3 (es) 1996-07-16
FI871695A (fi) 1987-10-19
DE3771548D1 (de) 1991-08-29
DE3613187A1 (de) 1987-10-22
IE871013L (en) 1987-10-18
PT84694B (pt) 1989-11-30
FI88359C (sv) 1993-05-10
DK192487D0 (da) 1987-04-14
ATE65396T1 (de) 1991-08-15

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Legal Events

Date Code Title Description
BB Publication of examined application
FG Patent granted

Owner name: HEINRICH MACK NACHF.

MA Patent expired