FI874311A7 - 7-/(meta-substituoitu)fenyyliglysiini/ -1-karba-1-detiakefalosporiinit. - Google Patents
7-/(meta-substituoitu)fenyyliglysiini/ -1-karba-1-detiakefalosporiinit. Download PDFInfo
- Publication number
- FI874311A7 FI874311A7 FI874311A FI874311A FI874311A7 FI 874311 A7 FI874311 A7 FI 874311A7 FI 874311 A FI874311 A FI 874311A FI 874311 A FI874311 A FI 874311A FI 874311 A7 FI874311 A7 FI 874311A7
- Authority
- FI
- Finland
- Prior art keywords
- dethiacephalosporins
- carba
- phenylglycine
- meta
- substituted
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D463/00—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D463/10—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D463/14—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hetero atoms directly attached in position 7
- C07D463/16—Nitrogen atoms
- C07D463/18—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof
- C07D463/20—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D463/22—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen further substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Cephalosporin Compounds (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US91517386A | 1986-10-03 | 1986-10-03 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| FI874311A0 FI874311A0 (fi) | 1987-10-01 |
| FI874311A7 true FI874311A7 (fi) | 1988-04-04 |
| FI874311L FI874311L (fi) | 1988-04-04 |
Family
ID=25435354
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI874311A FI874311L (fi) | 1986-10-03 | 1987-10-01 | 7-/(meta-substituerade)fenylglysin/ -1-karba-1-detiakefalosporiner. |
Country Status (17)
| Country | Link |
|---|---|
| EP (1) | EP0266896B1 (en:Method) |
| JP (1) | JPS6396186A (en:Method) |
| KR (1) | KR880005125A (en:Method) |
| CN (1) | CN87107149A (en:Method) |
| AT (2) | ATE79119T1 (en:Method) |
| BG (1) | BG47034A3 (en:Method) |
| DE (1) | DE3780909T2 (en:Method) |
| DK (1) | DK518487A (en:Method) |
| FI (1) | FI874311L (en:Method) |
| GR (1) | GR3005920T3 (en:Method) |
| HU (1) | HU200179B (en:Method) |
| IE (1) | IE872646L (en:Method) |
| IL (1) | IL84051A0 (en:Method) |
| NZ (1) | NZ222015A (en:Method) |
| PL (1) | PL151703B1 (en:Method) |
| PT (1) | PT85850B (en:Method) |
| ZA (1) | ZA877398B (en:Method) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SU1750429A3 (ru) * | 1988-02-05 | 1992-07-23 | Эли Лилли Энд Компани (Фирма) | Способ получени кристаллического 2,5-гидрата-1-карбацефалоспорина |
| US6982251B2 (en) | 2000-12-20 | 2006-01-03 | Schering Corporation | Substituted 2-azetidinones useful as hypocholesterolemic agents |
| SK287746B6 (sk) | 2001-01-26 | 2011-08-04 | Schering Corporation | Použitie substituovaných azetidinónových zlúčenín na liečenie sitosterolémie |
| PT1353696E (pt) | 2001-01-26 | 2007-02-28 | Schering Corp | Combinações de activador (es) do receptor activado por proliferador do peroxisoma (ppar) e inibidor (es) da absorção de esterol e tratamentos para indicações vasculares |
| US7071181B2 (en) | 2001-01-26 | 2006-07-04 | Schering Corporation | Methods and therapeutic combinations for the treatment of diabetes using sterol absorption inhibitors |
| IL157552A0 (en) | 2001-03-28 | 2004-03-28 | Schering Corp | Enantioselective synthesis of azetidinone intermediate compounds |
| US7053080B2 (en) | 2001-09-21 | 2006-05-30 | Schering Corporation | Methods and therapeutic combinations for the treatment of obesity using sterol absorption inhibitors |
| ATE345793T1 (de) | 2001-09-21 | 2006-12-15 | Schering Corp | Behandlung von xanthom mittels azetidinon- derivate als hemmer der sterol absorption |
| US7056906B2 (en) | 2001-09-21 | 2006-06-06 | Schering Corporation | Combinations of hormone replacement therapy composition(s) and sterol absorption inhibitor(s) and treatments for vascular conditions in post-menopausal women |
| WO2004037163A2 (en) * | 2002-05-14 | 2004-05-06 | Northwestern University | STERICALLY-AWKWARD β-LACTAMASE INHIBITORS |
| WO2004043457A1 (en) | 2002-11-06 | 2004-05-27 | Schering Corporation | Cholesterol absorptions inhibitors for the treatment of autoimmune disorders |
| MXPA05009501A (es) | 2003-03-07 | 2005-10-18 | Schering Corp | Compuestos de azetidinona sustituidos, formulaciones y usos de los mismos para el tratamiento de hipercolesterolemia. |
| ATE406364T1 (de) | 2003-03-07 | 2008-09-15 | Schering Corp | Substituierte azetidinon-derivate, deren pharmazeutische formulierungen und deren verwendung zur behandlung von hypercholesterolemia |
| US7459442B2 (en) | 2003-03-07 | 2008-12-02 | Schering Corporation | Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof |
| MXPA05009502A (es) | 2003-03-07 | 2005-10-18 | Schering Corp | Compuestos de azetidinona sustituidos, formulaciones y usos de los mismos para el tratamiento de hipercolesterolemia. |
| CN102144992B (zh) * | 2011-03-10 | 2013-04-10 | 浙江大学 | 苯基甘氨酸衍生物制备对金黄色葡萄球菌有抑菌和杀菌活性的抗菌剂的用途 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3697515A (en) * | 1963-02-18 | 1972-10-10 | Ciba Geigy Corp | Process for splitting the 7-n-acyl group from cephalosporin compounds |
| JPS5672698A (en) * | 1979-11-14 | 1981-06-16 | Kyowa Hakko Kogyo Co Ltd | Preparation of optically active cephalosporin analogue |
| NO155547C (no) * | 1979-02-10 | 1987-04-15 | Kyowa Hakko Kogyo Kk | Optisk aktive cefalosporin-analoge og salter derav samt fremgangsmaate for deres fremstilling. |
| NO155548C (no) * | 1979-02-10 | 1987-04-15 | Kyowa Hakko Kogyo Kk | Fremgangsmaate til fremstilling av optisk aktive cefalosporin-analoger. |
| JPS60174787A (ja) * | 1984-02-21 | 1985-09-09 | Kyowa Hakko Kogyo Co Ltd | ３位置換カルバセフエム化合物 |
| US4673737A (en) * | 1985-08-02 | 1987-06-16 | Harvard University | 7-acylamino-(or 7-amino)-3-trifluoromethylsulfonyloxy-1-carba(1-dethia)-3-cephem-4-carboxylic acids and esters thereof |
-
1987
- 1987-10-01 FI FI874311A patent/FI874311L/fi not_active IP Right Cessation
- 1987-10-01 IL IL84051A patent/IL84051A0/xx unknown
- 1987-10-01 ZA ZA877398A patent/ZA877398B/xx unknown
- 1987-10-01 PT PT85850A patent/PT85850B/pt unknown
- 1987-10-01 DE DE8787308713T patent/DE3780909T2/de not_active Expired - Fee Related
- 1987-10-01 EP EP87308713A patent/EP0266896B1/en not_active Expired - Lifetime
- 1987-10-01 NZ NZ222015A patent/NZ222015A/xx unknown
- 1987-10-01 AT AT87308713T patent/ATE79119T1/de not_active IP Right Cessation
- 1987-10-01 CN CN198787107149A patent/CN87107149A/zh active Pending
- 1987-10-02 IE IE872646A patent/IE872646L/xx unknown
- 1987-10-02 JP JP62250552A patent/JPS6396186A/ja active Pending
- 1987-10-02 HU HU874452A patent/HU200179B/hu not_active IP Right Cessation
- 1987-10-02 KR KR870011038A patent/KR880005125A/ko not_active Withdrawn
- 1987-10-02 BG BG081345A patent/BG47034A3/xx unknown
- 1987-10-02 DK DK518487A patent/DK518487A/da not_active Application Discontinuation
- 1987-10-02 PL PL1987268034A patent/PL151703B1/pl unknown
- 1987-10-08 AT AT0257587A patent/AT388377B/de active
-
1992
- 1992-10-08 GR GR920402240T patent/GR3005920T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NZ222015A (en) | 1989-10-27 |
| BG47034A3 (bg) | 1990-04-16 |
| PT85850B (en) | 1990-01-12 |
| PL151703B1 (en) | 1990-09-28 |
| EP0266896B1 (en) | 1992-08-05 |
| JPS6396186A (ja) | 1988-04-27 |
| DK518487D0 (da) | 1987-10-02 |
| PT85850A (en) | 1987-11-01 |
| ZA877398B (en) | 1989-05-30 |
| KR880005125A (ko) | 1988-06-28 |
| HU200179B (en) | 1990-04-28 |
| AU7926987A (en) | 1988-04-14 |
| DK518487A (da) | 1988-04-04 |
| FI874311A0 (fi) | 1987-10-01 |
| IL84051A0 (en) | 1988-03-31 |
| FI874311L (fi) | 1988-04-04 |
| AT388377B (de) | 1989-06-12 |
| DE3780909D1 (en) | 1992-09-10 |
| IE872646L (en) | 1988-04-03 |
| PL268034A1 (en) | 1988-09-01 |
| AU591811B2 (en) | 1989-12-14 |
| GR3005920T3 (en:Method) | 1993-06-07 |
| ATA257587A (de) | 1988-11-15 |
| HUT45053A (en) | 1988-05-30 |
| DE3780909T2 (de) | 1993-03-04 |
| EP0266896A1 (en) | 1988-05-11 |
| ATE79119T1 (de) | 1992-08-15 |
| CN87107149A (zh) | 1988-05-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Patent granted |
Owner name: BIOHIT OY |
|
| BB | Publication of examined application | ||
| MM | Patent lapsed |
Owner name: ELI LILLY AND COMPANY |