FI871445A0 - Foerfarande foer framstaellning av nya spergualinderivat. - Google Patents

Foerfarande foer framstaellning av nya spergualinderivat.

Info

Publication number
FI871445A0
FI871445A0 FI871445A FI871445A FI871445A0 FI 871445 A0 FI871445 A0 FI 871445A0 FI 871445 A FI871445 A FI 871445A FI 871445 A FI871445 A FI 871445A FI 871445 A0 FI871445 A0 FI 871445A0
Authority
FI
Finland
Prior art keywords
spergualinderivat
nya
compounds
foerfarande foer
foer framstaellning
Prior art date
Application number
FI871445A
Other languages
English (en)
Other versions
FI86546C (fi
FI86546B (fi
FI871445A (fi
Inventor
Hamao Umezawa
Tomio Takeuchi
Tetsushi Saino
Masao Yoshida
Katsutoshi Takahashi
Teruya Nakamura
Original Assignee
Microbial Chem Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Microbial Chem Res Found filed Critical Microbial Chem Res Found
Publication of FI871445A0 publication Critical patent/FI871445A0/fi
Publication of FI871445A publication Critical patent/FI871445A/fi
Application granted granted Critical
Publication of FI86546B publication Critical patent/FI86546B/fi
Publication of FI86546C publication Critical patent/FI86546C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
    • C07C279/14—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by carboxyl groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/18—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to carbon atoms of six-membered aromatic rings
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Transplantation (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Electric Propulsion And Braking For Vehicles (AREA)
  • Train Traffic Observation, Control, And Security (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Pyrrole Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
FI871445A 1986-04-04 1987-04-02 Foerfarande foer framstaellning av nya terapeutiskt anvaendbara spergualinderivat. FI86546C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP7774786 1986-04-04
JP7774786 1986-04-04

Publications (4)

Publication Number Publication Date
FI871445A0 true FI871445A0 (fi) 1987-04-02
FI871445A FI871445A (fi) 1987-10-05
FI86546B FI86546B (fi) 1992-05-29
FI86546C FI86546C (fi) 1992-09-10

Family

ID=13642505

Family Applications (1)

Application Number Title Priority Date Filing Date
FI871445A FI86546C (fi) 1986-04-04 1987-04-02 Foerfarande foer framstaellning av nya terapeutiskt anvaendbara spergualinderivat.

Country Status (17)

Country Link
US (1) US4956504A (fi)
EP (1) EP0241797B1 (fi)
JP (1) JPH0745460B2 (fi)
KR (2) KR940006768B1 (fi)
CN (1) CN1016341B (fi)
AT (1) ATE64378T1 (fi)
AU (1) AU599092B2 (fi)
CA (1) CA1305827C (fi)
DE (1) DE3770680D1 (fi)
DK (2) DK171487A (fi)
ES (1) ES2039213T3 (fi)
FI (1) FI86546C (fi)
GR (1) GR3002660T3 (fi)
HU (1) HU204069B (fi)
IE (1) IE60077B1 (fi)
PT (1) PT84620B (fi)
ZA (1) ZA872440B (fi)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0794424B2 (ja) * 1987-09-30 1995-10-11 財団法人微生物化学研究会 新スパガリン関連化合物およびその製造法
US5770625A (en) * 1988-02-08 1998-06-23 The Trustees Of Columbia University In The City Of New York Butyryl-tyrosinyl spermine, analogs thereof and methods of preparing and using same
US4990536A (en) * 1989-04-03 1991-02-05 Nippon Kayaku Kabushiki Kaisha Immunopotentiator and spergualin-related compound therefor
YU48230B (sh) * 1989-05-29 1997-08-22 Takara Shuzo Co.Ltd. Kristalni deoksispergvalin i postupak za njegovo pripremanje
US5086069A (en) * 1990-02-05 1992-02-04 Rorer Pharmaceutical Corporation Anti-thrombotic peptide and pseudopeptide derivatives
DE69104291T2 (de) * 1990-07-20 1995-05-18 Takara Shuzo Co Spergulinähnliche Verbindungen und ihre Verwendung.
JPH08503920A (ja) * 1991-04-11 1996-04-30 ローヌ−プーラン ローラー インターナショナル（ホウルディングス） インコーポレイテッド 抗血栓ペプチドおよび偽ペプチド誘導体
WO1994004140A1 (en) * 1992-08-19 1994-03-03 Nippon Kayaku Kabushiki Kaisha Antiprotozoan drug
FR2698628B1 (fr) * 1992-12-02 1995-02-17 Fournier Ind & Sante Analogues de 15-déoxyspergualine, leur procédé de préparation et leur utilisation en thérapeutique.
GB9726569D0 (en) * 1997-12-16 1998-02-11 Univ Southampton Neuroprotective agents
US20020142000A1 (en) * 1999-01-15 2002-10-03 Digan Mary Ellen Anti-CD3 immunotoxins and therapeutic uses therefor
KR100604206B1 (ko) * 2005-12-01 2006-07-24 박현미 배선용 단자

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5748957A (en) * 1980-09-08 1982-03-20 Microbial Chem Res Found Novel antibiotic bmg 162-af2, its preparation and carcinostatic agent comprising it as active ingredient
JPS57185254A (en) * 1981-05-11 1982-11-15 Microbial Chem Res Found Novel carcinostatic substances and their preparation
JPS5862152A (ja) * 1981-10-08 1983-04-13 Microbial Chem Res Found Ｎ−〔４−（３−アミノプロピル）アミノブチル〕−２−（ω−グアニジノ脂肪酸アミド）−２−ヒドロキシエタンアミドおよびその誘導体ならびにその製造法
JPS5942356A (ja) * 1982-09-02 1984-03-08 Microbial Chem Res Found スパガリン関連化合物およびその製造法
US4525299A (en) * 1983-05-10 1985-06-25 Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai (-)-15-Deoxyspergualin, process for the preparation thereof, and intermediate of the same
JPS60104099A (ja) * 1983-11-09 1985-06-08 Nippon Kayaku Co Ltd スパガリン関連化合物の新規製造法
JPS60181056A (ja) * 1984-02-29 1985-09-14 Takara Shuzo Co Ltd Ν−〔４−（３−アミノプロピル）アミノブチル〕−２，２−ジヒドロキシエタンアミドの製造法
JPS60185758A (ja) * 1984-03-02 1985-09-21 Microbial Chem Res Found フエニレン基を有するスパガリン関連化合物およびその製造法
JPS61165322A (ja) * 1985-01-14 1986-07-26 Microbial Chem Res Found スパガリン類の注射用凍結乾燥製剤
AU587691B2 (en) * 1987-03-30 1989-08-24 Shosuke Okamoto Phenylalanine derivative and proteinase inhibitor

Also Published As

Publication number Publication date
ATE64378T1 (de) 1991-06-15
FI86546C (fi) 1992-09-10
HUT44577A (en) 1988-03-28
KR870009989A (ko) 1987-11-30
CN87102538A (zh) 1987-11-18
CA1305827C (en) 1992-07-28
KR940006768B1 (ko) 1994-07-27
AU599092B2 (en) 1990-07-12
PT84620B (pt) 1989-11-30
IE60077B1 (en) 1994-06-01
AU7107587A (en) 1987-10-08
DK102792D0 (da) 1992-08-18
US4956504A (en) 1990-09-11
PT84620A (en) 1987-05-01
JPS6345247A (ja) 1988-02-26
EP0241797A3 (en) 1988-07-20
HU204069B (en) 1991-11-28
DK171487A (da) 1987-10-05
KR890001965A (ko) 1989-04-06
KR940007743B1 (ko) 1994-08-24
JPH0745460B2 (ja) 1995-05-17
FI86546B (fi) 1992-05-29
FI871445A (fi) 1987-10-05
EP0241797B1 (en) 1991-06-12
ZA872440B (en) 1987-12-30
DK171487D0 (da) 1987-04-03
ES2039213T3 (es) 1993-09-16
DE3770680D1 (de) 1991-07-18
IE870864L (en) 1987-10-04
GR3002660T3 (en) 1993-01-25
DK102792A (da) 1992-08-18
EP0241797A2 (en) 1987-10-21
CN1016341B (zh) 1992-04-22

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Legal Events

Date Code Title Description
MM Patent lapsed
MM Patent lapsed

Owner name: MICROBIAL CHEMISTRY RESEARCH FOUNDATION