FI865187A0 - Förfarande för framställning av fusionsproteiner som innehåller en eukaryot ballastandel och produkter som är användbara vid förfarandet - Google Patents

Förfarande för framställning av fusionsproteiner som innehåller en eukaryot ballastandel och produkter som är användbara vid förfarandet

Info

Publication number
FI865187A0
FI865187A0 FI865187A FI865187A FI865187A0 FI 865187 A0 FI865187 A0 FI 865187A0 FI 865187 A FI865187 A FI 865187A FI 865187 A FI865187 A FI 865187A FI 865187 A0 FI865187 A0 FI 865187A0
Authority
FI
Finland
Prior art keywords
fusion proteins
eukaryotic
preparation
ballast portion
proteins containing
Prior art date
Application number
FI865187A
Other languages
English (en)
Finnish (fi)
Other versions
FI93734B (sv
FI865187A (sv
FI93734C (sv
Inventor
Paul Habermann
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of FI865187A0 publication Critical patent/FI865187A0/sv
Publication of FI865187A publication Critical patent/FI865187A/sv
Publication of FI93734B publication Critical patent/FI93734B/sv
Application granted granted Critical
Publication of FI93734C publication Critical patent/FI93734C/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/815—Protease inhibitors from leeches, e.g. hirudin, eglin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/53—Colony-stimulating factor [CSF]
    • C07K14/535—Granulocyte CSF; Granulocyte-macrophage CSF
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/55—IL-2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Veterinary Medicine (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Plant Pathology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FI865187A 1985-12-21 1986-12-18 Förfarande för framställning av fusionsproteiner som innehåller en eukaryot ballastandel och produkter som är användbara vid förfarandet FI93734C (sv)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE3545565 1985-12-21
DE3545565 1985-12-21
DE3636903 1986-10-30
DE19863636903 DE3636903A1 (de) 1985-12-21 1986-10-30 Fusionsproteine mit eukaryotischem ballastanteil

Publications (4)

Publication Number Publication Date
FI865187A0 true FI865187A0 (sv) 1986-12-18
FI865187A FI865187A (sv) 1987-06-22
FI93734B FI93734B (sv) 1995-02-15
FI93734C FI93734C (sv) 1995-05-26

Family

ID=25839208

Family Applications (1)

Application Number Title Priority Date Filing Date
FI865187A FI93734C (sv) 1985-12-21 1986-12-18 Förfarande för framställning av fusionsproteiner som innehåller en eukaryot ballastandel och produkter som är användbara vid förfarandet

Country Status (16)

Country Link
EP (1) EP0229998B1 (sv)
JP (2) JP2553058B2 (sv)
KR (1) KR950000301B1 (sv)
AT (1) ATE78296T1 (sv)
AU (1) AU599943B2 (sv)
CA (1) CA1339894C (sv)
DE (1) DE3636903A1 (sv)
DK (1) DK168823B1 (sv)
ES (1) ES2033678T3 (sv)
FI (1) FI93734C (sv)
GR (1) GR3005985T3 (sv)
HU (1) HU209747B (sv)
IE (1) IE58935B1 (sv)
IL (1) IL81018A (sv)
NO (1) NO175003C (sv)
PT (1) PT83973B (sv)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3545568A1 (de) * 1985-12-21 1987-07-16 Hoechst Ag Gm-csf-protein, seine derivate, herstellung solcher proteine und ihre verwendung
DE3844211A1 (de) * 1988-12-29 1990-07-05 Hoechst Ag Neue insulinderivate, verfahren zu deren herstellung, ihre verwendung und eine sie enthaltende pharmazeutische zubereitung
FR2643646B1 (fr) * 1989-02-27 1993-09-17 Pasteur Institut Expression de sequences de nucleotides codant pour des vesicules a gaz
CU22222A1 (es) * 1989-08-03 1995-01-31 Cigb Procedimiento para la expresion de proteinas heterologicas producidas de forma fusionada en escherichia coli, su uso, vectores de expresion y cepas recombinantes
DE3942580A1 (de) * 1989-12-22 1991-06-27 Basf Ag Verfahren zur herstellung von hirudin
DE4105480A1 (de) * 1991-02-21 1992-08-27 Boehringer Mannheim Gmbh Verbesserte aktivierung von rekombinanten proteinen
PT821006E (pt) 1996-07-26 2004-09-30 Aventis Pharma Gmbh Derivados de insulina com ligacao a zinco aumentada
DE19825447A1 (de) 1998-06-06 1999-12-09 Hoechst Marion Roussel De Gmbh Neue Insulinanaloga mit erhöhter Zinkbildung
DE102006031955A1 (de) 2006-07-11 2008-01-17 Sanofi-Aventis Deutschland Gmbh Verfahren zur Herstellung von Insulinanaloga mit dibasischem B-Kettenende
DE102006031962A1 (de) 2006-07-11 2008-01-17 Sanofi-Aventis Deutschland Gmbh Amidiertes Insulin Glargin
CA2740685C (en) 2008-10-17 2018-09-11 Sanofi-Aventis Deutschland Gmbh Combination of an insulin and a glp-1 agonist
JP5973918B2 (ja) 2009-11-13 2016-08-23 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング Ｇｌｐ−１アゴニスト及びメチオニンを含む薬学的組成物
AU2010317995B2 (en) 2009-11-13 2014-04-17 Sanofi-Aventis Deutschland Gmbh Pharmaceutical composition comprising a GLP-1 agonist, an insulin, and methionine
JP6199186B2 (ja) 2010-08-30 2017-09-20 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング ２型糖尿病の治療用の医薬の製造のためのａｖｅ００１０の使用
US9821032B2 (en) 2011-05-13 2017-11-21 Sanofi-Aventis Deutschland Gmbh Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin
RU2650616C2 (ru) 2011-08-29 2018-04-16 Санофи-Авентис Дойчланд Гмбх Фармацевтическая комбинация для применения при гликемическом контроле у пациентов с сахарным диабетом 2 типа
TWI559929B (en) 2011-09-01 2016-12-01 Sanofi Aventis Deutschland Pharmaceutical composition for use in the treatment of a neurodegenerative disease
HRP20230470T1 (hr) 2014-12-12 2023-07-21 Sanofi-Aventis Deutschland Gmbh Formulacija fiksnog omjera inzulin glargin/liksisenatid
TWI748945B (zh) 2015-03-13 2021-12-11 德商賽諾菲阿凡提斯德意志有限公司 第２型糖尿病病患治療
TW201705975A (zh) 2015-03-18 2017-02-16 賽諾菲阿凡提斯德意志有限公司 第２型糖尿病病患之治療
KR20200080748A (ko) 2018-12-27 2020-07-07 주식회사 폴루스 음이온 교환 크로마토그래피를 이용한 인슐린 전구체의 정제방법
KR20200080747A (ko) 2018-12-27 2020-07-07 주식회사 폴루스 인슐린 전구체의 인슐린 효소 전환용 조성물 및 이를 이용하여 인슐린 전구체를 인슐린으로 전환하는 방법

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK108685A (da) * 1984-03-19 1985-09-20 Fujisawa Pharmaceutical Co Vaekstfaktor i
EP0158198A1 (en) * 1984-03-29 1985-10-16 Takeda Chemical Industries, Ltd. DNA and use thereof
GB8412517D0 (en) * 1984-05-16 1984-06-20 Nagai K Recombinant fusion proteins

Also Published As

Publication number Publication date
AU6676086A (en) 1987-06-25
FI93734B (sv) 1995-02-15
DK619186A (da) 1987-06-22
NO865192L (no) 1987-06-22
HU209747B (en) 1994-10-28
ATE78296T1 (de) 1992-08-15
KR870006187A (ko) 1987-07-09
JPH08187089A (ja) 1996-07-23
NO175003C (no) 1994-08-17
IL81018A (en) 1992-03-29
PT83973A (de) 1987-01-01
DE3636903A1 (de) 1987-07-02
PT83973B (pt) 1989-07-31
GR3005985T3 (sv) 1993-06-07
EP0229998B1 (de) 1992-07-15
IE58935B1 (en) 1993-12-01
CA1339894C (en) 1998-06-02
JP2774260B2 (ja) 1998-07-09
AU599943B2 (en) 1990-08-02
NO865192D0 (no) 1986-12-19
EP0229998A3 (en) 1988-08-03
EP0229998A2 (de) 1987-07-29
JP2553058B2 (ja) 1996-11-13
FI865187A (sv) 1987-06-22
ES2033678T3 (es) 1993-04-01
KR950000301B1 (ko) 1995-01-13
NO175003B (no) 1994-05-09
IL81018A0 (en) 1987-03-31
HUT44614A (en) 1988-03-28
DK168823B1 (da) 1994-06-20
JPS62167799A (ja) 1987-07-24
FI93734C (sv) 1995-05-26
IE863334L (en) 1987-06-21
DK619186D0 (da) 1986-12-19

Similar Documents

Publication Publication Date Title
FI865187A0 (sv) Förfarande för framställning av fusionsproteiner som innehåller en eukaryot ballastandel och produkter som är användbara vid förfarandet
PT83761B (pt) Metodo para a producao de interleuquina-4 de mamifero
FI863041A (fi) Fusionsprotein, foerfarande foer deras framstaellning och deras anvaendning.

Legal Events

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BB Publication of examined application
FG Patent granted

Owner name: HOECHST AKTIENGESELLSCHAFT

MA Patent expired