FI863352A0 - Gem-dihalogen-1,8-diamino-4-azaoktaner. - Google Patents

Gem-dihalogen-1,8-diamino-4-azaoktaner.

Info

Publication number
FI863352A0
FI863352A0 FI863352A FI863352A FI863352A0 FI 863352 A0 FI863352 A0 FI 863352A0 FI 863352 A FI863352 A FI 863352A FI 863352 A FI863352 A FI 863352A FI 863352 A0 FI863352 A0 FI 863352A0
Authority
FI
Finland
Prior art keywords
azaoktaner
dihalo
gem
diamino
Prior art date
Application number
FI863352A
Other languages
English (en)
Other versions
FI84816B (fi
FI863352A (fi
FI84816C (fi
Inventor
Fritz Gerhart
Pierre Mamont
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of FI863352A0 publication Critical patent/FI863352A0/fi
Publication of FI863352A publication Critical patent/FI863352A/fi
Publication of FI84816B publication Critical patent/FI84816B/fi
Application granted granted Critical
Publication of FI84816C publication Critical patent/FI84816C/fi

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
    • C07C211/02—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C211/15—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton the carbon skeleton being further substituted by halogen atoms or by nitro or nitroso groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Radiology & Medical Imaging (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
  • Indole Compounds (AREA)
FI863352A 1985-08-21 1986-08-19 Foerfarande foer framstaellning av terapeutiskt aktiva gem-difluor-1,8-diamino-4-azaoktanderivat. FI84816C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/767,928 US4695654A (en) 1985-08-21 1985-08-21 Gem-dihalo-1,8-diamino-4-aza-octanes
US76792885 1985-08-21

Publications (4)

Publication Number Publication Date
FI863352A0 true FI863352A0 (fi) 1986-08-19
FI863352A FI863352A (fi) 1987-02-22
FI84816B FI84816B (fi) 1991-10-15
FI84816C FI84816C (fi) 1992-01-27

Family

ID=25080994

Family Applications (1)

Application Number Title Priority Date Filing Date
FI863352A FI84816C (fi) 1985-08-21 1986-08-19 Foerfarande foer framstaellning av terapeutiskt aktiva gem-difluor-1,8-diamino-4-azaoktanderivat.

Country Status (20)

Country Link
US (2) US4695654A (fi)
EP (1) EP0215319B1 (fi)
JP (1) JPH0667880B2 (fi)
KR (1) KR900006132B1 (fi)
CN (1) CN1012732B (fi)
AR (1) AR242018A1 (fi)
AT (1) ATE68471T1 (fi)
AU (1) AU584730B2 (fi)
CA (1) CA1265159C (fi)
DE (1) DE3682007D1 (fi)
DK (1) DK396886A (fi)
ES (1) ES2001108A6 (fi)
FI (1) FI84816C (fi)
GR (1) GR862149B (fi)
HU (1) HU200987B (fi)
IL (1) IL79752A0 (fi)
NO (1) NO164972C (fi)
NZ (1) NZ217248A (fi)
PT (1) PT83231B (fi)
ZA (1) ZA866181B (fi)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1274547A (en) * 1985-08-21 1990-09-25 Fritz Gerhart Gem-dihalo and tetrahalo-1,12-diamino-4, 9-diaza-dodecanes
NO884565L (no) * 1987-10-15 1989-04-17 Univ Moskovsk Preparat for kontrastdannelse ved diagnose av ondartet neoplasma.
EP0338168A1 (en) * 1988-04-19 1989-10-25 Merrell Dow Pharmaceuticals Inc. Phosphonoalkylpurine derivatives
GB9301898D0 (en) * 1993-01-30 1993-03-17 Univ Liverpool Method for localising and measuring the profileration of cancer and compositions for same
US5834456A (en) * 1996-02-23 1998-11-10 The Dow Chemical Company Polyazamacrocyclofluoromonoalkylphosphonic acids, and their complexes, for use as contrast agents
CN114685325B (zh) * 2020-12-29 2024-05-28 苏州瑞博生物技术股份有限公司 一种含胺化合物及其制备方法和用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4004996A (en) * 1974-12-23 1977-01-25 Merck & Co., Inc. Fluorination of organic compounds
GB2082579B (en) * 1980-08-23 1984-02-08 Merrell Toraude & Co Fluorinated diaminobutane derivatives
US4720489A (en) * 1984-10-15 1988-01-19 Douglas Shander Hair growth modification with ornithine decarboxylase inhibitors
CA1274547A (en) * 1985-08-21 1990-09-25 Fritz Gerhart Gem-dihalo and tetrahalo-1,12-diamino-4, 9-diaza-dodecanes

Also Published As

Publication number Publication date
JPS6245564A (ja) 1987-02-27
DK396886D0 (da) 1986-08-20
CA1265159A (en) 1990-01-30
CA1265159C (en) 1990-01-30
HU200987B (en) 1990-09-28
HUT44753A (en) 1988-04-28
PT83231A (en) 1986-09-01
NO863343L (no) 1987-02-23
AU584730B2 (en) 1989-06-01
EP0215319A3 (en) 1988-12-14
US4851448A (en) 1989-07-25
FI84816B (fi) 1991-10-15
EP0215319B1 (en) 1991-10-16
EP0215319A2 (en) 1987-03-25
FI863352A (fi) 1987-02-22
NO164972B (no) 1990-08-27
ZA866181B (en) 1987-04-29
NO164972C (no) 1990-12-05
DK396886A (da) 1987-02-22
KR870002045A (ko) 1987-03-28
IL79752A0 (en) 1986-11-30
ES2001108A6 (es) 1988-04-16
NZ217248A (en) 1989-05-29
NO863343D0 (no) 1986-08-20
FI84816C (fi) 1992-01-27
AU6155886A (en) 1987-02-26
GR862149B (en) 1986-12-23
CN86105154A (zh) 1987-04-22
PT83231B (pt) 1988-07-01
AR242018A1 (es) 1993-02-26
US4695654A (en) 1987-09-22
JPH0667880B2 (ja) 1994-08-31
DE3682007D1 (de) 1991-11-21
KR900006132B1 (ko) 1990-08-24
ATE68471T1 (de) 1991-11-15
CN1012732B (zh) 1991-06-05

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Legal Events

Date Code Title Description
MM Patent lapsed
MM Patent lapsed

Owner name: MERRELL DOW PHARMACEUTICALS INC.