FI862642A - 3-(substituerade) propenylaminotiazol-yl-kefalosporansyror och deras estrar. - Google Patents

3-(substituerade) propenylaminotiazol-yl-kefalosporansyror och deras estrar. Download PDF

Info

Publication number
FI862642A
FI862642A FI862642A FI862642A FI862642A FI 862642 A FI862642 A FI 862642A FI 862642 A FI862642 A FI 862642A FI 862642 A FI862642 A FI 862642A FI 862642 A FI862642 A FI 862642A
Authority
FI
Finland
Prior art keywords
propenylaminotiazole
kefalosporansyror
estrar
substituerade
och deras
Prior art date
Application number
FI862642A
Other languages
English (en)
Other versions
FI85487C (fi
FI85487B (fi
FI862642A0 (fi
Inventor
Seiji Iimura
Yoshio Abe
Jun Okumura
Takayuki Naito
Hajime Kamachi
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of FI862642A0 publication Critical patent/FI862642A0/fi
Publication of FI862642A publication Critical patent/FI862642A/fi
Application granted granted Critical
Publication of FI85487B publication Critical patent/FI85487B/fi
Publication of FI85487C publication Critical patent/FI85487C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/22—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with radicals containing only hydrogen and carbon atoms, attached in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI862642A 1985-06-24 1986-06-19 Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 3- propenylaminotiazolylcefalosporansyror och estrar. FI85487C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/748,359 US4708955A (en) 1985-06-24 1985-06-24 3-(substituted)propenyl-7-aminothiazol-ylcephalosporanic acids and esters thereof
US74835985 1985-06-24

Publications (4)

Publication Number Publication Date
FI862642A0 FI862642A0 (fi) 1986-06-19
FI862642A true FI862642A (fi) 1986-12-25
FI85487B FI85487B (fi) 1992-01-15
FI85487C FI85487C (fi) 1992-04-27

Family

ID=25009129

Family Applications (1)

Application Number Title Priority Date Filing Date
FI862642A FI85487C (fi) 1985-06-24 1986-06-19 Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 3- propenylaminotiazolylcefalosporansyror och estrar.

Country Status (36)

Country Link
US (1) US4708955A (fi)
JP (1) JPS62491A (fi)
KR (1) KR930007416B1 (fi)
AR (1) AR244233A1 (fi)
AT (1) AT390956B (fi)
AU (1) AU593557B2 (fi)
BE (1) BE904983A (fi)
CA (1) CA1279868C (fi)
CS (1) CS258142B2 (fi)
CY (1) CY1618A (fi)
DD (1) DD246112A5 (fi)
DE (1) DE3620995A1 (fi)
DK (1) DK295386A (fi)
EG (1) EG17868A (fi)
ES (1) ES8800680A1 (fi)
FI (1) FI85487C (fi)
FR (1) FR2583757B1 (fi)
GB (1) GB2178032B (fi)
GR (1) GR861611B (fi)
HK (1) HK106091A (fi)
HU (1) HU199484B (fi)
IE (1) IE59123B1 (fi)
IL (1) IL79181A0 (fi)
IT (1) IT1221767B (fi)
LU (1) LU86488A1 (fi)
MY (1) MY102073A (fi)
NL (1) NL8601645A (fi)
NZ (1) NZ216614A (fi)
OA (1) OA08349A (fi)
PH (2) PH21206A (fi)
PT (1) PT82836B (fi)
SE (1) SE500218C2 (fi)
SG (1) SG91691G (fi)
SU (1) SU1428204A3 (fi)
YU (1) YU45787B (fi)
ZA (1) ZA864297B (fi)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4874856A (en) * 1985-06-24 1989-10-17 Bristol-Myers Company 3-(substituted)propenyl-7-(aminothiazolylacetamido) ceph-3-em-4-carboxylic acids and esters thereof
GB8519606D0 (en) * 1985-08-05 1985-09-11 Fujisawa Pharmaceutical Co 3 7-d substituted-3-cephem compounds
US4870168A (en) * 1987-02-26 1989-09-26 Bristol-Myers Company 3-Unsaturated alkyl cephems from 3-triflyl cephems
FR2622585B1 (fr) * 1987-11-03 1991-04-19 Roussel Uclaf Nouvelles cephalosporines comportant en position 3 un radical vinyle substitue, leur procede de preparation, leur application comme medicaments, les compositions les renfermant et les nouveaux intermediaires obtenus
US4935508A (en) * 1988-08-23 1990-06-19 Bristol-Myers Company Process for cephem prodrug esters
US5143911A (en) * 1990-08-23 1992-09-01 Bristol-Myers Squibb Company Antibiotic c-3 di-hydroxyphenyl substituted cephalosporin compounds, compositions and method of use thereof
JP2825655B2 (ja) * 1992-02-05 1998-11-18 バイオケミ・ゲゼルシヤフト・エム・ベー・ハー ３−セフェム−４−カルボン酸誘導体の精製方法
JPH07173168A (ja) * 1993-07-14 1995-07-11 Sumitomo Chem Co Ltd セフェム系化合物、その製法、およびそれのセフェム系抗生物質製造への利用
KR100408430B1 (ko) * 2001-04-18 2003-12-06 한미약품 주식회사 3-(ｚ)-프로페닐 세펨 화합물의 선택적인 제조 방법
WO2005042543A1 (en) * 2003-10-30 2005-05-12 Cj Corporation Processes for the preparation of cephem derivatives

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3917778A (en) * 1968-04-13 1975-11-04 Tdk Electronics Co Ltd Method for slip casting soft ferromagnetic ferrites
GB1399086A (en) * 1971-05-14 1975-06-25 Glaxo Lab Ltd Cephalosporin compounds
US4065620A (en) * 1971-06-14 1977-12-27 Eli Lilly And Company 3-(Substituted) vinyl cephalosporins
FR2345153A1 (fr) * 1976-03-25 1977-10-21 Roussel Uclaf Nouvelles alcoyloximes derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
US4464369A (en) * 1977-03-14 1984-08-07 Fujisawa Pharmaceutical Co., Ltd. 7-Acylamino-3-cephem-4-carboxylic acid derivatives and pharmaceutical compositions
GB2051788B (en) * 1979-05-23 1984-01-18 Rhone Poulenc Ind 3 - thiovinyl - cephalosporins their preparation and compositions containing them
FR2457296A1 (fr) * 1979-05-23 1980-12-19 Rhone Poulenc Ind Nouveaux derives de vinyl-3 cephalosporines et leur preparation
FR2457297A1 (fr) * 1979-05-23 1980-12-19 Rhone Poulenc Ind Nouvelles vinyl-3 cephalosporines, et leur preparation
US4409214A (en) * 1979-11-19 1983-10-11 Fujisawa Pharmaceutical, Co., Ltd. 7-Acylamino-3-vinylcephalosporanic acid derivatives and processes for the preparation thereof
FR2494275A2 (fr) * 1980-11-20 1982-05-21 Rhone Poulenc Ind Nouveaux derives de vinyl-3 cephalosporines et leur preparation
FR2494276A2 (fr) * 1980-11-20 1982-05-21 Rhone Poulenc Ind Nouvelles vinyl-3 cephalosporines, et leur preparation
FR2494280A1 (fr) * 1980-11-20 1982-05-21 Rhone Poulenc Ind Nouveaux derives de la cephalosporine et leur preparation
IE53429B1 (en) * 1981-08-03 1988-11-09 Fujisawa Pharmaceutical Co New cephem compounds and processes for preparation thereof
DK162718C (da) * 1982-09-30 1992-05-11 Fujisawa Pharmaceutical Co Analogifremgangsmaade til fremstilling af 7-substitueret-3-vinyl-3-cephemforbindelser
GB8323034D0 (en) * 1983-08-26 1983-09-28 Fujisawo Pharmaceutical Co Ltd 7-substituted-3-vinyl-3-cephem compounds
US4520022A (en) * 1983-01-28 1985-05-28 Bristol-Myers Company Substituted vinyl cephalosporins
US4486586A (en) * 1983-02-10 1984-12-04 Bristol-Myers Company Cephalosporin derivatives
CA1276929C (en) * 1984-04-09 1990-11-27 Masahisa Oka Cephalosporin antibacterial agents
GB8411954D0 (en) * 1984-05-10 1984-06-13 Glaxo Group Ltd Cephalosporin antibiotics
FR2580652B1 (fr) * 1985-04-22 1989-01-06 Bristol Myers Co Acide 7-amino-3-propenylcephalosporanique et ses esters

Also Published As

Publication number Publication date
NZ216614A (en) 1990-03-27
HUT43074A (en) 1987-09-28
GB2178032A (en) 1987-02-04
US4708955A (en) 1987-11-24
SE8602780L (sv) 1986-12-25
CY1618A (en) 1992-07-10
GB2178032B (en) 1989-04-26
IT8620894A0 (it) 1986-06-24
AU593557B2 (en) 1990-02-15
YU45787B (sh) 1992-07-20
PH21206A (en) 1987-08-19
PT82836A (en) 1986-07-01
ATA171986A (de) 1990-01-15
NL8601645A (nl) 1987-01-16
PH21879A (en) 1988-03-25
IT1221767B (it) 1990-07-12
DK295386D0 (da) 1986-06-23
GR861611B (en) 1986-10-30
AR244233A1 (es) 1993-10-29
FI85487C (fi) 1992-04-27
IL79181A0 (en) 1986-09-30
CA1279868C (en) 1991-02-05
FI85487B (fi) 1992-01-15
CS258142B2 (en) 1988-07-15
PT82836B (pt) 1989-01-17
OA08349A (fr) 1988-02-29
SE500218C2 (sv) 1994-05-09
YU110086A (en) 1987-10-31
LU86488A1 (fr) 1987-01-13
FR2583757B1 (fr) 1989-01-13
ES556465A0 (es) 1987-11-01
SG91691G (en) 1991-12-13
JPS62491A (ja) 1987-01-06
DD246112A5 (de) 1987-05-27
AU5882186A (en) 1987-01-08
HU199484B (en) 1990-02-28
SU1428204A3 (ru) 1988-09-30
AT390956B (de) 1990-07-25
DE3620995A1 (de) 1987-01-08
MY102073A (en) 1992-03-31
IE59123B1 (en) 1994-01-12
FI862642A0 (fi) 1986-06-19
ZA864297B (en) 1987-02-25
EG17868A (en) 1994-01-30
FR2583757A1 (fr) 1986-12-26
BE904983A (fr) 1986-12-23
HK106091A (en) 1992-01-03
SE8602780D0 (sv) 1986-06-23
IE861670L (en) 1986-12-24
CS462486A2 (en) 1987-11-12
GB8615253D0 (en) 1986-07-30
KR870000342A (ko) 1987-02-18
DK295386A (da) 1986-12-25
ES8800680A1 (es) 1987-11-01
KR930007416B1 (ko) 1993-08-10

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MM Patent lapsed
MM Patent lapsed

Owner name: BRISTOL-MYERS SQUIBB COMPANY