FI861683A - N-indolyletyl-sulfonsyra-amider, foerfarande foer deras framstaellning och deras anvaendning. - Google Patents

N-indolyletyl-sulfonsyra-amider, foerfarande foer deras framstaellning och deras anvaendning. Download PDF

Info

Publication number
FI861683A
FI861683A FI861683A FI861683A FI861683A FI 861683 A FI861683 A FI 861683A FI 861683 A FI861683 A FI 861683A FI 861683 A FI861683 A FI 861683A FI 861683 A FI861683 A FI 861683A
Authority
FI
Finland
Prior art keywords
deras
indolylethyl
sulphonyride
amider
foerfarande foer
Prior art date
Application number
FI861683A
Other languages
English (en)
Other versions
FI82036B (fi
FI82036C (fi
FI861683A0 (fi
Inventor
Horst Boeshagen
Ulrich Rosentreter
Folker Lieb
Hermann Oediger
Friedel Seuter
Elisabeth Perzborn
Volker-Bernd Fiedler
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of FI861683A0 publication Critical patent/FI861683A0/fi
Publication of FI861683A publication Critical patent/FI861683A/fi
Publication of FI82036B publication Critical patent/FI82036B/fi
Application granted granted Critical
Publication of FI82036C publication Critical patent/FI82036C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16—Tryptamines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
FI861683A 1985-04-24 1986-04-22 Foerfarande foer framstaellning av terapeutiskt anvaendbara n-indolyletylsulfonsyraamider. FI82036C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19853514696 DE3514696A1 (de) 1985-04-24 1985-04-24 N-indolylethyl-sulfonsaeureamide, verfahren zu ihrer herstellung und ihre verwendung
DE3514696 1985-04-24

Publications (4)

Publication Number Publication Date
FI861683A0 FI861683A0 (fi) 1986-04-22
FI861683A true FI861683A (fi) 1986-10-25
FI82036B FI82036B (fi) 1990-09-28
FI82036C FI82036C (fi) 1991-01-10

Family

ID=6268925

Family Applications (1)

Application Number Title Priority Date Filing Date
FI861683A FI82036C (fi) 1985-04-24 1986-04-22 Foerfarande foer framstaellning av terapeutiskt anvaendbara n-indolyletylsulfonsyraamider.

Country Status (18)

Country Link
US (1) US4774240A (fi)
EP (1) EP0201735B1 (fi)
JP (1) JPH0625104B2 (fi)
KR (1) KR930011299B1 (fi)
CN (1) CN1015054B (fi)
AT (1) ATE56433T1 (fi)
AU (1) AU590267B2 (fi)
CA (1) CA1321585C (fi)
DE (2) DE3514696A1 (fi)
DK (1) DK187186A (fi)
ES (1) ES8802381A1 (fi)
FI (1) FI82036C (fi)
GR (1) GR861058B (fi)
HU (1) HU195483B (fi)
IL (1) IL78557A0 (fi)
NO (1) NO167283C (fi)
PT (1) PT82442B (fi)
ZA (1) ZA863028B (fi)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3613623A1 (de) * 1986-04-23 1987-10-29 Bayer Ag N-dihydroindolylethyl-sulfonamide
GB8717374D0 (en) * 1987-07-22 1987-08-26 Smith Kline French Lab Pharmaceutically active compounds
DE3840338A1 (de) * 1988-11-30 1990-05-31 Bayer Ag Neue 2-halogensubstituierte n-indolylethyl-sulfonsaeureamide, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
US5153214A (en) * 1989-06-28 1992-10-06 Ciba-Geigy Corporation Certain (arylsulfonamido- and imidazolyl-)-substituted carboxylic acids and derivatives thereof and use for suppressing thromboxane activity
US5025025A (en) * 1989-06-28 1991-06-18 Ciba-Geigy Corporation (Arylsulfonamido- and pyridyl-)-substituted carboxylic acids and derivatives thereof and use for suppressing thromboxane activity
GB8924392D0 (en) * 1989-10-30 1989-12-20 Bayer Ag Substituted cycloalkano/b/dihydroindole-and-indolesulphonamides
GB9008108D0 (en) * 1990-04-10 1990-06-06 Bayer Ag Cycloalkano(b)dihydroindoles and-indolesulphonamides substituted by heterocycles
CA2064815C (en) * 1990-06-07 1999-11-16 Alan Duncan Robertson Therapeutic heterocyclic compounds
US5189054A (en) * 1990-11-02 1993-02-23 Merrell Dow Pharmaceuticals Inc. 3-amidoindolyl derivatives and pharmaceutical compositions thereof
US7605156B2 (en) * 2001-12-03 2009-10-20 Wyeth Methods for the use of inhibitors of cytosolic phospholipase A2
US6903215B2 (en) * 2002-03-26 2005-06-07 Boehringer Ingelheim Pharmaceuticals, Inc. Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof
US7534897B2 (en) * 2002-05-16 2009-05-19 Shionogi & Co., Ltd. Indole arylsulfonaimide compounds exhibiting PGD 2 receptor antagonism
CN1678306A (zh) * 2002-08-29 2005-10-05 贝林格尔·英格海姆药物公司 在炎性、变应性和增生性疾病中用作糖皮质激素模拟物的3－(磺酰氨基乙基)－吲哚衍生物
UY28526A1 (es) * 2003-09-24 2005-04-29 Boehringer Ingelheim Pharma Miméticos de glucocorticoides, métodos de preparación composiciones farmacéuticas y usos de los mismos
US7795272B2 (en) * 2004-03-13 2010-09-14 Boehringer Ingelheim Pharmaceutical, Inc. Glucocorticoid mimetics, methods of making them, pharmaceutical compositions and uses thereof
US7754755B2 (en) * 2004-09-23 2010-07-13 Bristol-Myers Squibb Company Inhibitors of 15-lipoxygenase
KR20070068432A (ko) * 2004-10-29 2007-06-29 아스트라제네카 아베 염증 질환의 치료를 위한 글루코코르티코이드 수용체조절제로서의 신규 술폰아미드 유도체
US7635711B2 (en) * 2004-12-27 2009-12-22 Boehringer-Ingelheim Pharmaceuticals, Inc. Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof
TW200829578A (en) 2006-11-23 2008-07-16 Astrazeneca Ab Chemical compounds 537
JP2010512331A (ja) * 2006-12-06 2010-04-22 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング グルココルチコイド模倣薬、それらの製造方法、医薬組成物、及びこれらの使用
JO2754B1 (en) 2006-12-21 2014-03-15 استرازينكا ايه بي Amylendazoleil derivatives for the treatment of glucocorticoid-mediated disorders
US7750027B2 (en) 2008-01-18 2010-07-06 Oxagen Limited Compounds having CRTH2 antagonist activity
SA109300309B1 (ar) 2008-05-20 2013-01-22 باير شيرنج فارما ايه جي مشتقات فينيل وبنزو داي أوكسينيل إندازول بها استبدال
MX2010013095A (es) * 2008-06-06 2010-12-21 Boehringer Ingelheim Int Mimeticos de glucocorticoides, metodos para su fabricacion, composiciones farmaceuticas y usos de los mismos.
GB201407820D0 (en) 2014-05-02 2014-06-18 Atopix Therapeutics Ltd Polymorphic form
GB201407807D0 (en) 2014-05-02 2014-06-18 Atopix Therapeutics Ltd Polymorphic form
CN105399697A (zh) * 2014-09-12 2016-03-16 苏州旺山旺水生物医药有限公司 一种氨基磺酰基类化合物、其制备方法及用途

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1332410C (en) * 1984-06-26 1994-10-11 Roger M. Freidinger Benzodiazepine analogs

Also Published As

Publication number Publication date
FI82036B (fi) 1990-09-28
FI82036C (fi) 1991-01-10
ATE56433T1 (de) 1990-09-15
AU5672686A (en) 1986-10-30
CN1015054B (zh) 1991-12-11
NO861366L (no) 1986-10-27
KR860008137A (ko) 1986-11-12
PT82442A (en) 1986-05-01
US4774240A (en) 1988-09-27
ES8802381A1 (es) 1988-05-16
IL78557A0 (en) 1986-08-31
ZA863028B (en) 1987-12-30
GR861058B (en) 1986-08-19
ES554285A0 (es) 1988-05-16
DE3514696A1 (de) 1986-11-06
HUT41385A (en) 1987-04-28
DE3674059D1 (de) 1990-10-18
NO167283C (no) 1991-10-23
AU590267B2 (en) 1989-11-02
EP0201735A1 (de) 1986-11-20
FI861683A0 (fi) 1986-04-22
KR930011299B1 (ko) 1993-11-29
DK187186A (da) 1986-10-25
EP0201735B1 (de) 1990-09-12
NO167283B (no) 1991-07-15
JPS61249960A (ja) 1986-11-07
HU195483B (en) 1988-05-30
DK187186D0 (da) 1986-04-23
PT82442B (pt) 1988-11-30
CA1321585C (en) 1993-08-24
JPH0625104B2 (ja) 1994-04-06
CN86102761A (zh) 1987-02-25

Similar Documents

Publication Publication Date Title
FI861683A (fi) N-indolyletyl-sulfonsyra-amider, foerfarande foer deras framstaellning och deras anvaendning.
FI904327A0 (fi) N-substituerad-4-pyrimidinaminer och -pyrimidindiaminer, foerfarande foer deras framstaellning och deras anvaendning som laekemedel.
NO179867C (no) Sulfonamido- og sulfonamidokarbonyl-pyridin-2-karboksylsyreamider og anvendelse av forbindelsene som legemidler
ES2061452T3 (es) Nuevas hetrazepinas y procedimiento para su preparacion.
KR960705815A (ko) 신규한 피라진 카복스아미드 유도체, 이의 제조방법 및 약제에 있어서의 이의 용도(Novel pyrazine carboxamide derivatives, their production and their use in medicaments)
DK163287A (da) 1,4-diazepiner og farmaceutiske midler med indhold af saadanne forbindelser
SE8600413D0 (sv) Nytt lekemedel och sett att framstella detsamma
DE3881073D1 (de) Naphthalenverbindungen und antiallergische und antiinflammatorische pharmazeutische mittel.
SE8802412L (sv) Tiokarbamidderivat
NO903148D0 (no) Hemoreguleringspeptider.
DE69126758T2 (de) Benzamid-Derivate
FI840109A0 (fi) Foereningar foer behandling av hoegt blodtryck
DE3778642D1 (de) Therapeutikum zur behandlung von magengeschwueren.
ES2138226T3 (es) Derivados del acido imidazo(1,2-a)indeno(1,2-e)pirazina-2-carboxilico, su preparacion y los medicamentos que les contienen.
IE860987L (en) Triazole derivatives
DE3678622D1 (de) Leukotrienantagonisten.
ES2075137T3 (es) Compuestos sustituidos de piridina; su produccion y composiciones farmaceuticas que los contienen.
ATE8260T1 (de) 2-(n-(2-fluor-6-bromphenyl)-n-(thiemyl-2-methyl - amino)-2-imidazolin, dessen saeureadditionssalze, diese enthaltende arzneimittel und verfahren zur herstellung derselben.
ES2121071T3 (es) Compuestos de oxazolidina y su empleo como medicamentos.
ATE31925T1 (de) 2-(formylamino)-n-(1h-tetrazol-5-yl)benzamide.
SU1783774A1 (ru) Натриевая соль n-(3-хлорбутен-2-ил)антраниловой кислоты, проявляющая противовоспалительную и анальгетическую активность

Legal Events

Date Code Title Description
MM Patent lapsed
MM Patent lapsed

Owner name: BAYER AKTIENGESELLSCHAFT