FI861357A0 - Derivat av metylenbisfosfonsyra, foerfarande foer deras framstaellning och en faramceutisk blandning. - Google Patents
Derivat av metylenbisfosfonsyra, foerfarande foer deras framstaellning och en faramceutisk blandning.Info
- Publication number
- FI861357A0 FI861357A0 FI861357A FI861357A FI861357A0 FI 861357 A0 FI861357 A0 FI 861357A0 FI 861357 A FI861357 A FI 861357A FI 861357 A FI861357 A FI 861357A FI 861357 A0 FI861357 A0 FI 861357A0
- Authority
- FI
- Finland
- Prior art keywords
- methylenbisphosphonsyra
- faramceutisk
- blandning
- derivatives
- foerfarande foer
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
- C07F9/3839—Polyphosphonic acids
- C07F9/386—Polyphosphonic acids containing hydroxy substituents in the hydrocarbon radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Nutrition Science (AREA)
- Endocrinology (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB848419489A GB8419489D0 (en) | 1984-07-31 | 1984-07-31 | Chemical compounds |
PCT/DK1985/000071 WO1986000902A1 (en) | 1984-07-31 | 1985-07-25 | Derivatives of methylene-bisphosphonic acid, process for their preparation and a pharmaceutical composition |
Publications (2)
Publication Number | Publication Date |
---|---|
FI861357A FI861357A (fi) | 1986-03-27 |
FI861357A0 true FI861357A0 (fi) | 1986-03-27 |
Family
ID=10564711
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI861357A FI861357A0 (fi) | 1984-07-31 | 1986-03-27 | Derivat av metylenbisfosfonsyra, foerfarande foer deras framstaellning och en faramceutisk blandning. |
Country Status (15)
Country | Link |
---|---|
US (1) | US4732998A (xx) |
EP (1) | EP0191044B1 (xx) |
JP (1) | JPH068303B2 (xx) |
KR (1) | KR860700254A (xx) |
AU (1) | AU583848B2 (xx) |
DE (1) | DE3575929D1 (xx) |
DK (1) | DK167808B1 (xx) |
ES (1) | ES8707964A1 (xx) |
FI (1) | FI861357A0 (xx) |
GB (1) | GB8419489D0 (xx) |
GR (1) | GR851865B (xx) |
IE (1) | IE58614B1 (xx) |
PT (1) | PT80886B (xx) |
WO (1) | WO1986000902A1 (xx) |
ZA (1) | ZA855264B (xx) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3805663A1 (de) * | 1988-02-24 | 1989-09-07 | Henkel Kgaa | Oxaalkanpolyphosphonsaeuren, ihre verwendung als thresholder sowie diese verbindungen enthaltende, komplexierend wirkende zusammensetzungen |
DE3822650A1 (de) * | 1988-07-05 | 1990-02-01 | Boehringer Mannheim Gmbh | Neue diphosphonsaeurederivate, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel |
US5266722A (en) * | 1988-11-09 | 1993-11-30 | W. R. Grace & Co.-Conn. | Polyether bis-phosphonic acid compounds |
PH26923A (en) * | 1989-03-08 | 1992-12-03 | Ciba Geigy | N-substituted amino alkanediphosphonic acids |
FI83421C (fi) * | 1989-06-21 | 1991-07-10 | Huhtamaeki Oy | Foerfarande foer framstaellning av farmakologiskt anvaendbara metylenbisfosfonsyraderivat. |
US5227506A (en) * | 1989-09-06 | 1993-07-13 | Merck & Co., Inc. | Acyloxymethyl esters of bisphosphonic acids as bone resorption inhibitors |
EP0416689B1 (en) * | 1989-09-06 | 1995-11-29 | Merck & Co. Inc. | Acyloxymethyl esters of bisphosphonic acids as bone resorption inhibitors |
GB9024345D0 (en) * | 1990-11-08 | 1990-12-19 | Merck Sharp & Dohme | Therapeutic agents |
JP3141053B2 (ja) * | 1991-12-26 | 2001-03-05 | アベンティス ファーマ株式会社 | ビスホスホン酸誘導体 |
US5200554A (en) * | 1992-01-21 | 1993-04-06 | Nasman Jan Anders H | Bisphosphonic acid derivatives and their use |
ES2155446T3 (es) * | 1992-07-10 | 2001-05-16 | Toray Industries | Derivado de metanodifosfonato, su produccion y su uso farmaceutico. |
FR2703590B1 (fr) * | 1993-04-05 | 1995-06-30 | Sanofi Elf | Utilisation de derives d'acide bisphosphonique pour la preparation de medicaments destines a favoriser la reparation osseuse . |
US20010007863A1 (en) * | 1998-06-18 | 2001-07-12 | Merck & Co., Inc. | Wet granulation formulation for bisphosphonic acids |
US6315566B1 (en) | 1999-05-18 | 2001-11-13 | 3M Innovative Properties Company | Dental materials |
US6143919A (en) * | 1999-05-18 | 2000-11-07 | 3M Innovative Properties Company | Polymerizable acidic compounds and methods of preparation |
EP1435970A4 (en) * | 2001-10-18 | 2005-05-04 | Ilex Products Inc | METHOD OF TREATING SKIN WITH DIPHOSPHONATE DERIVATIVES |
DE102004032781A1 (de) * | 2004-01-23 | 2005-08-11 | Mcs Micro Carrier Systems Gmbh | Bisphosphonsäurederivate |
JP2006028024A (ja) * | 2004-07-12 | 2006-02-02 | Toray Ind Inc | リン含有有機化合物の製造方法。 |
EP2289900A1 (en) * | 2009-08-26 | 2011-03-02 | Humboldt Universität zu Berlin | Bisphosphonates as inhibitors of acid sphingomyelinase |
CA2878413A1 (en) * | 2012-07-05 | 2014-01-09 | University Of Iowa Research Foundation | Therapeutic bisphosphonates |
CN109312171A (zh) * | 2016-02-22 | 2019-02-05 | 表面活性剂科技公司 | 包括溶解在氟化溶剂中的双膦酸根型化合物的组合物及其用于覆盖部件表面的用途 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA777769A (en) * | 1963-03-18 | 1968-02-06 | H. Roy Clarence | Substituted methylene diphosphonic acid compounds and detergent compositions |
US3400131A (en) * | 1964-03-05 | 1968-09-03 | Hoffmann La Roche | 1, 3-di (4-pyridyl)-2-propanol derivatives |
GB1115044A (en) * | 1964-08-06 | 1968-05-22 | Albright & Wilson Mfg Ltd | Derivatives of hydroxy diphosphonic acids |
AT279051B (de) * | 1966-12-29 | 1970-02-25 | Procter & Gamble | Mundpflegemittel |
US3400151A (en) * | 1967-12-28 | 1968-09-03 | Procter & Gamble | Bicyclic dimer of ethane-1-hydroxy-1, 1-diphosphonic acid and salts thereof |
US4014959A (en) * | 1975-04-24 | 1977-03-29 | Monsanto Company | Phosphonoether carboxylates |
SU772152A1 (ru) * | 1977-07-20 | 1983-02-15 | Центральный научно-исследовательский институт оловянной промышленности | 1-Алкоксиалкилиден-1,1-дифосфоновые кислоты или их калиевые,натриевые или аммониевые соли в качестве собирателей дл флотации касситерита и способ их получени |
IT1201087B (it) * | 1982-04-15 | 1989-01-27 | Gentili Ist Spa | Bifosfonati farmacologicamente attivi,procedimento per la loro preparazione e relative composizioni farmaceutiche |
-
1984
- 1984-07-31 GB GB848419489A patent/GB8419489D0/en active Pending
-
1985
- 1985-07-08 IE IE171785A patent/IE58614B1/en not_active IP Right Cessation
- 1985-07-12 ZA ZA855264A patent/ZA855264B/xx unknown
- 1985-07-25 WO PCT/DK1985/000071 patent/WO1986000902A1/en active IP Right Grant
- 1985-07-25 AU AU46736/85A patent/AU583848B2/en not_active Ceased
- 1985-07-25 KR KR1019860700180A patent/KR860700254A/ko not_active Application Discontinuation
- 1985-07-25 DE DE8585903807T patent/DE3575929D1/de not_active Expired - Fee Related
- 1985-07-25 EP EP85903807A patent/EP0191044B1/en not_active Expired - Lifetime
- 1985-07-25 JP JP60503564A patent/JPH068303B2/ja not_active Expired - Lifetime
- 1985-07-25 US US06/852,248 patent/US4732998A/en not_active Expired - Fee Related
- 1985-07-29 GR GR851865A patent/GR851865B/el unknown
- 1985-07-30 PT PT80886A patent/PT80886B/pt not_active IP Right Cessation
- 1985-07-31 ES ES545783A patent/ES8707964A1/es not_active Expired
-
1986
- 1986-03-27 FI FI861357A patent/FI861357A0/fi not_active Application Discontinuation
- 1986-04-01 DK DK147386A patent/DK167808B1/da not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
PT80886A (en) | 1985-08-01 |
US4732998A (en) | 1988-03-22 |
GB8419489D0 (en) | 1984-09-05 |
PT80886B (pt) | 1987-11-30 |
ZA855264B (en) | 1986-03-26 |
AU4673685A (en) | 1986-02-25 |
AU583848B2 (en) | 1989-05-11 |
GR851865B (xx) | 1985-12-02 |
DK147386D0 (da) | 1986-04-01 |
IE851717L (en) | 1986-01-31 |
JPH068303B2 (ja) | 1994-02-02 |
EP0191044B1 (en) | 1990-02-07 |
FI861357A (fi) | 1986-03-27 |
DE3575929D1 (de) | 1990-03-15 |
DK167808B1 (da) | 1993-12-20 |
KR860700254A (ko) | 1986-08-01 |
IE58614B1 (en) | 1993-10-20 |
WO1986000902A1 (en) | 1986-02-13 |
JPS61503034A (ja) | 1986-12-25 |
DK147386A (da) | 1986-04-01 |
ES545783A0 (es) | 1987-09-01 |
ES8707964A1 (es) | 1987-09-01 |
EP0191044A1 (en) | 1986-08-20 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Application withdrawn |
Owner name: LEO PHARMACEUTICAL PRODUCTS LTD A/S (LOEVENS KEMIS |