FI85553B - Sammansaettning och foerfarande foer desinfektion av kontaktlinser. - Google Patents
Sammansaettning och foerfarande foer desinfektion av kontaktlinser. Download PDFInfo
- Publication number
- FI85553B FI85553B FI874192A FI874192A FI85553B FI 85553 B FI85553 B FI 85553B FI 874192 A FI874192 A FI 874192A FI 874192 A FI874192 A FI 874192A FI 85553 B FI85553 B FI 85553B
- Authority
- FI
- Finland
- Prior art keywords
- component
- disinfectant
- inactivation
- composition according
- indicator
- Prior art date
Links
- 239000000645 desinfectant Substances 0.000 claims description 44
- 239000000203 mixture Substances 0.000 claims description 44
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 claims description 33
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 32
- 238000004659 sterilization and disinfection Methods 0.000 claims description 15
- 239000002253 acid Substances 0.000 claims description 14
- 230000002779 inactivation Effects 0.000 claims description 13
- 230000008859 change Effects 0.000 claims description 10
- KJFMBFZCATUALV-UHFFFAOYSA-N phenolphthalein Chemical group C1=CC(O)=CC=C1C1(C=2C=CC(O)=CC=2)C2=CC=CC=C2C(=O)O1 KJFMBFZCATUALV-UHFFFAOYSA-N 0.000 claims description 10
- 230000000249 desinfective effect Effects 0.000 claims description 9
- 230000003111 delayed effect Effects 0.000 claims description 8
- 229910021645 metal ion Inorganic materials 0.000 claims description 8
- 238000000034 method Methods 0.000 claims description 8
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims description 7
- 239000011575 calcium Substances 0.000 claims description 7
- 239000008187 granular material Substances 0.000 claims description 6
- JLVVSXFLKOJNIY-UHFFFAOYSA-N Magnesium ion Chemical compound [Mg+2] JLVVSXFLKOJNIY-UHFFFAOYSA-N 0.000 claims description 5
- 229910001424 calcium ion Inorganic materials 0.000 claims description 5
- 229910001425 magnesium ion Inorganic materials 0.000 claims description 5
- 239000002245 particle Substances 0.000 claims description 4
- 239000007787 solid Substances 0.000 claims description 4
- 239000003826 tablet Substances 0.000 claims description 4
- 239000002775 capsule Substances 0.000 claims description 3
- 238000005660 chlorination reaction Methods 0.000 claims description 3
- 239000008188 pellet Substances 0.000 claims description 3
- 150000004965 peroxy acids Chemical class 0.000 claims description 3
- 239000000843 powder Substances 0.000 claims description 3
- 150000003467 sulfuric acid derivatives Chemical group 0.000 claims description 3
- 230000000536 complexating effect Effects 0.000 claims 1
- 230000003247 decreasing effect Effects 0.000 claims 1
- 239000002824 redox indicator Substances 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 description 37
- 239000000243 solution Substances 0.000 description 32
- 230000000415 inactivating effect Effects 0.000 description 31
- AKHNMLFCWUSKQB-UHFFFAOYSA-L sodium thiosulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=S AKHNMLFCWUSKQB-UHFFFAOYSA-L 0.000 description 12
- 235000019345 sodium thiosulphate Nutrition 0.000 description 12
- -1 strongly Chemical compound 0.000 description 11
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 description 10
- 239000000460 chlorine Substances 0.000 description 10
- 229910052801 chlorine Inorganic materials 0.000 description 10
- 239000004133 Sodium thiosulphate Substances 0.000 description 8
- 238000004140 cleaning Methods 0.000 description 7
- 239000008139 complexing agent Substances 0.000 description 7
- 150000001875 compounds Chemical class 0.000 description 7
- VTIIJXUACCWYHX-UHFFFAOYSA-L disodium;carboxylatooxy carbonate Chemical compound [Na+].[Na+].[O-]C(=O)OOC([O-])=O VTIIJXUACCWYHX-UHFFFAOYSA-L 0.000 description 7
- 229940045872 sodium percarbonate Drugs 0.000 description 7
- 238000000576 coating method Methods 0.000 description 6
- 239000002516 radical scavenger Substances 0.000 description 6
- 239000001577 tetrasodium phosphonato phosphate Substances 0.000 description 6
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 description 6
- GHXZTYHSJHQHIJ-UHFFFAOYSA-N Chlorhexidine Chemical compound C=1C=C(Cl)C=CC=1NC(N)=NC(N)=NCCCCCCN=C(N)N=C(N)NC1=CC=C(Cl)C=C1 GHXZTYHSJHQHIJ-UHFFFAOYSA-N 0.000 description 5
- OFOBLEOULBTSOW-UHFFFAOYSA-N Propanedioic acid Natural products OC(=O)CC(O)=O OFOBLEOULBTSOW-UHFFFAOYSA-N 0.000 description 5
- 229960003260 chlorhexidine Drugs 0.000 description 5
- 239000011248 coating agent Substances 0.000 description 5
- VZCYOOQTPOCHFL-UPHRSURJSA-N maleic acid Chemical compound OC(=O)\C=C/C(O)=O VZCYOOQTPOCHFL-UPHRSURJSA-N 0.000 description 5
- 239000011976 maleic acid Substances 0.000 description 5
- 239000000463 material Substances 0.000 description 5
- 229920000609 methyl cellulose Polymers 0.000 description 5
- 239000001923 methylcellulose Substances 0.000 description 5
- 150000002978 peroxides Chemical class 0.000 description 5
- 239000003755 preservative agent Substances 0.000 description 5
- BJEPYKJPYRNKOW-REOHCLBHSA-N (S)-malic acid Chemical compound OC(=O)[C@@H](O)CC(O)=O BJEPYKJPYRNKOW-REOHCLBHSA-N 0.000 description 4
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 4
- BJEPYKJPYRNKOW-UHFFFAOYSA-N alpha-hydroxysuccinic acid Natural products OC(=O)C(O)CC(O)=O BJEPYKJPYRNKOW-UHFFFAOYSA-N 0.000 description 4
- 238000011109 contamination Methods 0.000 description 4
- 239000001630 malic acid Substances 0.000 description 4
- 235000011090 malic acid Nutrition 0.000 description 4
- 239000007800 oxidant agent Substances 0.000 description 4
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 description 4
- 239000011734 sodium Substances 0.000 description 4
- 239000008399 tap water Substances 0.000 description 4
- 235000020679 tap water Nutrition 0.000 description 4
- AQLJVWUFPCUVLO-UHFFFAOYSA-N urea hydrogen peroxide Chemical compound OO.NC(N)=O AQLJVWUFPCUVLO-UHFFFAOYSA-N 0.000 description 4
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 3
- 239000004372 Polyvinyl alcohol Substances 0.000 description 3
- 150000007513 acids Chemical class 0.000 description 3
- XPPKVPWEQAFLFU-UHFFFAOYSA-J diphosphate(4-) Chemical compound [O-]P([O-])(=O)OP([O-])([O-])=O XPPKVPWEQAFLFU-UHFFFAOYSA-J 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- LYCAIKOWRPUZTN-UHFFFAOYSA-N ethylene glycol Natural products OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 3
- 230000007794 irritation Effects 0.000 description 3
- 229920003023 plastic Polymers 0.000 description 3
- 239000004033 plastic Substances 0.000 description 3
- 229920002451 polyvinyl alcohol Polymers 0.000 description 3
- 238000000746 purification Methods 0.000 description 3
- 229940048084 pyrophosphate Drugs 0.000 description 3
- 150000003839 salts Chemical class 0.000 description 3
- 229910052708 sodium Inorganic materials 0.000 description 3
- 239000011780 sodium chloride Substances 0.000 description 3
- FQENQNTWSFEDLI-UHFFFAOYSA-J sodium diphosphate Chemical compound [Na+].[Na+].[Na+].[Na+].[O-]P([O-])(=O)OP([O-])([O-])=O FQENQNTWSFEDLI-UHFFFAOYSA-J 0.000 description 3
- HRZFUMHJMZEROT-UHFFFAOYSA-L sodium disulfite Chemical compound [Na+].[Na+].[O-]S(=O)S([O-])(=O)=O HRZFUMHJMZEROT-UHFFFAOYSA-L 0.000 description 3
- GCLGEJMYGQKIIW-UHFFFAOYSA-H sodium hexametaphosphate Chemical compound [Na]OP1(=O)OP(=O)(O[Na])OP(=O)(O[Na])OP(=O)(O[Na])OP(=O)(O[Na])OP(=O)(O[Na])O1 GCLGEJMYGQKIIW-UHFFFAOYSA-H 0.000 description 3
- 235000019982 sodium hexametaphosphate Nutrition 0.000 description 3
- 235000010262 sodium metabisulphite Nutrition 0.000 description 3
- 229940048086 sodium pyrophosphate Drugs 0.000 description 3
- 235000019832 sodium triphosphate Nutrition 0.000 description 3
- 239000012730 sustained-release form Substances 0.000 description 3
- 235000019818 tetrasodium diphosphate Nutrition 0.000 description 3
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 2
- VZCYOOQTPOCHFL-OWOJBTEDSA-N Fumaric acid Chemical compound OC(=O)\C=C\C(O)=O VZCYOOQTPOCHFL-OWOJBTEDSA-N 0.000 description 2
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 description 2
- LCTONWCANYUPML-UHFFFAOYSA-M Pyruvate Chemical compound CC(=O)C([O-])=O LCTONWCANYUPML-UHFFFAOYSA-M 0.000 description 2
- LCTONWCANYUPML-UHFFFAOYSA-N Pyruvic acid Chemical compound CC(=O)C(O)=O LCTONWCANYUPML-UHFFFAOYSA-N 0.000 description 2
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 description 2
- 239000007975 buffered saline Substances 0.000 description 2
- 229910052791 calcium Inorganic materials 0.000 description 2
- 150000001732 carboxylic acid derivatives Chemical class 0.000 description 2
- 239000003638 chemical reducing agent Substances 0.000 description 2
- 239000013078 crystal Substances 0.000 description 2
- 230000009849 deactivation Effects 0.000 description 2
- 230000000382 dechlorinating effect Effects 0.000 description 2
- 235000011180 diphosphates Nutrition 0.000 description 2
- 238000002845 discoloration Methods 0.000 description 2
- 150000002083 enediols Chemical class 0.000 description 2
- BEFDCLMNVWHSGT-UHFFFAOYSA-N ethenylcyclopentane Chemical compound C=CC1CCCC1 BEFDCLMNVWHSGT-UHFFFAOYSA-N 0.000 description 2
- 231100000040 eye damage Toxicity 0.000 description 2
- 239000004615 ingredient Substances 0.000 description 2
- 150000002500 ions Chemical class 0.000 description 2
- 239000011777 magnesium Substances 0.000 description 2
- 229910052749 magnesium Inorganic materials 0.000 description 2
- 239000011159 matrix material Substances 0.000 description 2
- CXKWCBBOMKCUKX-UHFFFAOYSA-M methylene blue Chemical compound [Cl-].C1=CC(N(C)C)=CC2=[S+]C3=CC(N(C)C)=CC=C3N=C21 CXKWCBBOMKCUKX-UHFFFAOYSA-M 0.000 description 2
- 229960000907 methylthioninium chloride Drugs 0.000 description 2
- 231100000344 non-irritating Toxicity 0.000 description 2
- 230000033116 oxidation-reduction process Effects 0.000 description 2
- 239000000047 product Substances 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 229940076788 pyruvate Drugs 0.000 description 2
- 239000004296 sodium metabisulphite Substances 0.000 description 2
- GEHJYWRUCIMESM-UHFFFAOYSA-L sodium sulfite Chemical compound [Na+].[Na+].[O-]S([O-])=O GEHJYWRUCIMESM-UHFFFAOYSA-L 0.000 description 2
- MWNQXXOSWHCCOZ-UHFFFAOYSA-L sodium;oxido carbonate Chemical class [Na+].[O-]OC([O-])=O MWNQXXOSWHCCOZ-UHFFFAOYSA-L 0.000 description 2
- 235000010199 sorbic acid Nutrition 0.000 description 2
- 239000004334 sorbic acid Substances 0.000 description 2
- 229940075582 sorbic acid Drugs 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- RTKIYNMVFMVABJ-UHFFFAOYSA-L thimerosal Chemical compound [Na+].CC[Hg]SC1=CC=CC=C1C([O-])=O RTKIYNMVFMVABJ-UHFFFAOYSA-L 0.000 description 2
- 229960004906 thiomersal Drugs 0.000 description 2
- YNJSNEKCXVFDKW-UHFFFAOYSA-N 3-(5-amino-1h-indol-3-yl)-2-azaniumylpropanoate Chemical compound C1=C(N)C=C2C(CC(N)C(O)=O)=CNC2=C1 YNJSNEKCXVFDKW-UHFFFAOYSA-N 0.000 description 1
- IFDPVSBDNAQBRQ-UHFFFAOYSA-N 4-methylbenzenecarboperoxoic acid Chemical compound CC1=CC=C(C(=O)OO)C=C1 IFDPVSBDNAQBRQ-UHFFFAOYSA-N 0.000 description 1
- LSNNMFCWUKXFEE-UHFFFAOYSA-M Bisulfite Chemical compound OS([O-])=O LSNNMFCWUKXFEE-UHFFFAOYSA-M 0.000 description 1
- GAWIXWVDTYZWAW-UHFFFAOYSA-N C[CH]O Chemical group C[CH]O GAWIXWVDTYZWAW-UHFFFAOYSA-N 0.000 description 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 description 1
- 102000016938 Catalase Human genes 0.000 description 1
- 108010053835 Catalase Proteins 0.000 description 1
- LKDRXBCSQODPBY-VRPWFDPXSA-N D-fructopyranose Chemical compound OCC1(O)OC[C@@H](O)[C@@H](O)[C@@H]1O LKDRXBCSQODPBY-VRPWFDPXSA-N 0.000 description 1
- QXNVGIXVLWOKEQ-UHFFFAOYSA-N Disodium Chemical class [Na][Na] QXNVGIXVLWOKEQ-UHFFFAOYSA-N 0.000 description 1
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 description 1
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 1
- 229930195725 Mannitol Natural products 0.000 description 1
- 229910003252 NaBO2 Inorganic materials 0.000 description 1
- 229920003171 Poly (ethylene oxide) Polymers 0.000 description 1
- 239000002202 Polyethylene glycol Substances 0.000 description 1
- 229920000388 Polyphosphate Polymers 0.000 description 1
- DWAQJAXMDSEUJJ-UHFFFAOYSA-M Sodium bisulfite Chemical compound [Na+].OS([O-])=O DWAQJAXMDSEUJJ-UHFFFAOYSA-M 0.000 description 1
- DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical compound [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 description 1
- 229930006000 Sucrose Natural products 0.000 description 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 description 1
- LSNNMFCWUKXFEE-UHFFFAOYSA-N Sulfurous acid Chemical class OS(O)=O LSNNMFCWUKXFEE-UHFFFAOYSA-N 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 239000012670 alkaline solution Substances 0.000 description 1
- 125000000217 alkyl group Chemical group 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 239000012736 aqueous medium Substances 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 125000003118 aryl group Chemical group 0.000 description 1
- 235000010323 ascorbic acid Nutrition 0.000 description 1
- 239000011668 ascorbic acid Substances 0.000 description 1
- 229960005070 ascorbic acid Drugs 0.000 description 1
- 230000000712 assembly Effects 0.000 description 1
- 238000000429 assembly Methods 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 239000003899 bactericide agent Substances 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 229960001506 brilliant green Drugs 0.000 description 1
- HXCILVUBKWANLN-UHFFFAOYSA-N brilliant green cation Chemical compound C1=CC(N(CC)CC)=CC=C1C(C=1C=CC=CC=1)=C1C=CC(=[N+](CC)CC)C=C1 HXCILVUBKWANLN-UHFFFAOYSA-N 0.000 description 1
- 239000000872 buffer Substances 0.000 description 1
- 125000005587 carbonate group Chemical group 0.000 description 1
- 150000004649 carbonic acid derivatives Chemical class 0.000 description 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 description 1
- 239000001913 cellulose Substances 0.000 description 1
- 229920002678 cellulose Polymers 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- SURLGNKAQXKNSP-DBLYXWCISA-N chlorin Chemical compound C\1=C/2\N/C(=C\C3=N/C(=C\C=4NC(/C=C\5/C=CC/1=N/5)=CC=4)/C=C3)/CC\2 SURLGNKAQXKNSP-DBLYXWCISA-N 0.000 description 1
- 239000012320 chlorinating reagent Substances 0.000 description 1
- 239000012141 concentrate Substances 0.000 description 1
- 239000000882 contact lens solution Substances 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 239000007857 degradation product Substances 0.000 description 1
- 239000004205 dimethyl polysiloxane Substances 0.000 description 1
- 235000013870 dimethyl polysiloxane Nutrition 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 239000000975 dye Substances 0.000 description 1
- 239000001530 fumaric acid Substances 0.000 description 1
- 229960002598 fumaric acid Drugs 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 150000004676 glycans Chemical class 0.000 description 1
- 238000005469 granulation Methods 0.000 description 1
- 230000003179 granulation Effects 0.000 description 1
- XLYOFNOQVPJJNP-ZSJDYOACSA-N heavy water Substances [2H]O[2H] XLYOFNOQVPJJNP-ZSJDYOACSA-N 0.000 description 1
- 230000002209 hydrophobic effect Effects 0.000 description 1
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 description 1
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 description 1
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 description 1
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 description 1
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 description 1
- 230000000937 inactivator Effects 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 239000000644 isotonic solution Substances 0.000 description 1
- 239000008101 lactose Substances 0.000 description 1
- 229940098895 maleic acid Drugs 0.000 description 1
- 239000000594 mannitol Substances 0.000 description 1
- 235000010355 mannitol Nutrition 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000002609 medium Substances 0.000 description 1
- 150000004972 metal peroxides Chemical class 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000007935 neutral effect Effects 0.000 description 1
- 230000003472 neutralizing effect Effects 0.000 description 1
- 150000007524 organic acids Chemical class 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 238000010525 oxidative degradation reaction Methods 0.000 description 1
- 230000001590 oxidative effect Effects 0.000 description 1
- 239000003002 pH adjusting agent Substances 0.000 description 1
- 150000004686 pentahydrates Chemical group 0.000 description 1
- 125000005342 perphosphate group Chemical group 0.000 description 1
- JRKICGRDRMAZLK-UHFFFAOYSA-L persulfate group Chemical group S(=O)(=O)([O-])OOS(=O)(=O)[O-] JRKICGRDRMAZLK-UHFFFAOYSA-L 0.000 description 1
- 239000007793 ph indicator Substances 0.000 description 1
- 239000000546 pharmaceutical excipient Substances 0.000 description 1
- 125000002467 phosphate group Chemical group [H]OP(=O)(O[H])O[*] 0.000 description 1
- 229910052697 platinum Inorganic materials 0.000 description 1
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 description 1
- 229920003229 poly(methyl methacrylate) Polymers 0.000 description 1
- 229920001223 polyethylene glycol Polymers 0.000 description 1
- 229920002338 polyhydroxyethylmethacrylate Polymers 0.000 description 1
- 239000004926 polymethyl methacrylate Substances 0.000 description 1
- 229920005862 polyol Polymers 0.000 description 1
- 150000003077 polyols Chemical class 0.000 description 1
- 239000001205 polyphosphate Substances 0.000 description 1
- 235000011176 polyphosphates Nutrition 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 239000008213 purified water Substances 0.000 description 1
- 229940107700 pyruvic acid Drugs 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 238000009877 rendering Methods 0.000 description 1
- 239000011347 resin Substances 0.000 description 1
- 229920005989 resin Polymers 0.000 description 1
- 238000005070 sampling Methods 0.000 description 1
- 229920006395 saturated elastomer Polymers 0.000 description 1
- 235000010267 sodium hydrogen sulphite Nutrition 0.000 description 1
- 239000004289 sodium hydrogen sulphite Substances 0.000 description 1
- 235000019333 sodium laurylsulphate Nutrition 0.000 description 1
- 229940001584 sodium metabisulfite Drugs 0.000 description 1
- NVIFVTYDZMXWGX-UHFFFAOYSA-N sodium metaborate Chemical compound [Na+].[O-]B=O NVIFVTYDZMXWGX-UHFFFAOYSA-N 0.000 description 1
- 229960001922 sodium perborate Drugs 0.000 description 1
- 235000010265 sodium sulphite Nutrition 0.000 description 1
- YKLJGMBLPUQQOI-UHFFFAOYSA-M sodium;oxidooxy(oxo)borane Chemical compound [Na+].[O-]OB=O YKLJGMBLPUQQOI-UHFFFAOYSA-M 0.000 description 1
- WSWCOQWTEOXDQX-MQQKCMAXSA-N sorbic acid group Chemical group C(\C=C\C=C\C)(=O)O WSWCOQWTEOXDQX-MQQKCMAXSA-N 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 239000003206 sterilizing agent Substances 0.000 description 1
- 125000003107 substituted aryl group Chemical group 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 239000011593 sulfur Substances 0.000 description 1
- 229910052717 sulfur Inorganic materials 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 230000002123 temporal effect Effects 0.000 description 1
- 150000004764 thiosulfuric acid derivatives Chemical class 0.000 description 1
- AAAQKTZKLRYKHR-UHFFFAOYSA-N triphenylmethane Chemical compound C1=CC=CC=C1C(C=1C=CC=CC=1)C1=CC=CC=C1 AAAQKTZKLRYKHR-UHFFFAOYSA-N 0.000 description 1
- 229920002554 vinyl polymer Polymers 0.000 description 1
- 239000012224 working solution Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L12/00—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor
- A61L12/08—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor using chemical substances
- A61L12/12—Non-macromolecular oxygen-containing compounds, e.g. hydrogen peroxide or ozone
- A61L12/124—Hydrogen peroxide; Peroxy compounds
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Apparatus For Disinfection Or Sterilisation (AREA)
- Eyeglasses (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Detergent Compositions (AREA)
Claims (10)
1. Sammansättning för desinfektion av kontaktlinser, vilken sammansättning är i fast form för tillsats tili vatten och innefattar en desinfektionskomponent för kontaktlinser, vilken förmar tjäna som en kalla för väteperoxid i kontakt med vatten och en inaktiveringskomponent, vilken förmär göra desinfektionskomponenten acceptabel för ögat, vilken inakti-veringskomponent är i fördröjd utlösningsform känne-t e c k n a d därav att ytterligare inkluderad är en färg-förändringsindikator sadan att vid inaktivering av desinfektionskomponenten medelst inaktiveringskomponenten en synbar färgförändring uppkommer.
2. En sammansättning enligt patentkravet 1, känne-t e c k n a d därav att färgförändringsindikatorn är en redoxindikator eller en syra/bas indikator.
3. En sammansättning enligt patentkravet 2, känne- t e c k n a d därav att inaktiveringen av desinfektionskompo-nenten är associerad med ett sjunkande pH värde och att indikatorn är en syra/bas indikator känslig för nämnda pH '·; förändring.
4. En sammansättning enligt patentkravet 3, känne- tecknad därav att nämnda indikator är fenolftalein.
5. En sammansättning enligt patentkravet 1, känne- t e c k n a d därav att desinfektionskomponenten är ett organiskt hydroperoxidat, ett oorganiskt hydroperoxidat eller en peroxisyra.
6. En sammansättning enligt patentkravet 1, känne-t e c k n a d därav att inaktiveringskomponenten är ett svavelsyrlighet derivat. I: i9 8 5 553
7. En sammansättning enligt nagot av de föregäende patent-kraven, kännetecknad därav att den innehäller en metalljon-komplexerande komponent för kalcium- och/eller mag-nesiumjoner och/eller en avkloreringskomponent.
8. En sammansättning enligt patentkravet 1, känne tecknad därav att den är i form av en tablett med en kärna med fördröjd utlösning av inaktiveringskomponent och desinfektionskomponenten utanför kärnan.
9. En sammansättning enligt patentkravet 1, känne tecknad därav att den är i tablett-, kapsel-, granulat-, pulver-, eller pellets- form och innehäller partiklar av desinfektionskomponent och partiklar med fördröjd utlösning av inaktiveringskomponent.
10. Ett förfarande för desinfektion av en kontaktlins kännetecknat därav att man sammanför linsen med vatten innehällande en sammansättning enligt nagot av patent-kraven 1-10 och tillater desinfektionskomponenten att desinfektera linsen och inaktiveringskomponenten att frigöras och göra den kvarvarande desinfektionskomponenten acceptabel *·.: för ögat och därigenom ge nämnda färgförändring.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB858507678A GB8507678D0 (en) | 1985-03-25 | 1985-03-25 | Cleaning/disinfection of contact lenses |
| GB8507678 | 1985-03-25 | ||
| GB8600168 | 1986-03-24 | ||
| PCT/GB1986/000168 WO1986005695A1 (en) | 1985-03-25 | 1986-03-24 | Cleaning and/or disinfection of contact lenses |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| FI874192L FI874192L (fi) | 1987-09-24 |
| FI874192A0 FI874192A0 (fi) | 1987-09-24 |
| FI85553B true FI85553B (fi) | 1992-01-31 |
| FI85553C FI85553C (sv) | 1992-05-11 |
Family
ID=10576581
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI874192A FI85553C (sv) | 1985-03-25 | 1987-09-24 | Sammansättning och förfarande för desinfektion av kontaktlinser |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US4863627A (sv) |
| EP (1) | EP0250427B1 (sv) |
| JP (1) | JPH0677597B2 (sv) |
| AU (1) | AU584189B2 (sv) |
| BR (1) | BR8607091A (sv) |
| DE (1) | DE3675018D1 (sv) |
| DK (1) | DK165818C (sv) |
| FI (1) | FI85553C (sv) |
| GB (2) | GB8507678D0 (sv) |
| HU (1) | HU198845B (sv) |
| WO (1) | WO1986005695A1 (sv) |
Families Citing this family (73)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3666914D1 (en) * | 1985-07-10 | 1989-12-21 | Ciba Geigy Ag | Cleaning set for contact lenses |
| GB2189045B (en) * | 1986-03-22 | 1990-11-28 | Smith & Nephew Ass | Disinfecting contact lenses using sulphur dioxide. |
| DE3701129A1 (de) * | 1987-01-16 | 1988-07-28 | Henkel Kgaa | Verfahren zur herstellung von desinfizierend wirkenden kontaktlinsen-reinigungsmitteltabletten |
| JPH0729883B2 (ja) * | 1987-12-18 | 1995-04-05 | ホーヤ株式会社 | コンタクトレンズ殺菌用組成物 |
| CA2003198C (en) * | 1988-11-29 | 1995-03-21 | Anthony J. Dziabo, Jr. | Aqueous ophthalmic solutions and method for preserving same |
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| JP3188448B2 (ja) | 1989-12-15 | 2001-07-16 | ノバルティス アクチエンゲゼル シャフト | ｐＨを調節されたタンパク質除去洗浄剤 |
| US5306352A (en) * | 1989-12-28 | 1994-04-26 | Ciba-Geigy Corporation | Peroxide disinfection method |
| US5152912A (en) * | 1990-01-05 | 1992-10-06 | Allergan, Inc. | Chlorine dioxide precursor containing compositions useful in disinfecting contact lenses |
| US5320806A (en) * | 1990-01-05 | 1994-06-14 | Allegan, Inc. | Methods to disinfect contact lenses |
| JPH05503453A (ja) * | 1990-02-27 | 1993-06-10 | アラーガン、インコーポレイテッド | 過酸化水素分解組成物並びにその製法および使用方法 |
| CA2075474A1 (en) * | 1990-02-27 | 1991-08-28 | Peter Gyulai | Hydrogen peroxide destroying compositions and methods of using same |
| ZA913506B (en) * | 1990-05-22 | 1992-02-26 | Alcon Lab Inc | Double redox system for disinfecting contact lenses |
| GB9012790D0 (en) * | 1990-06-08 | 1990-08-01 | Interox Chemicals Ltd | Food storage |
| AU8626991A (en) * | 1990-09-25 | 1992-04-15 | Allergan, Inc. | Apparatus and method for disinfecting a contact lens and detecting the presence of an oxidative disinfectant |
| DE69123458T2 (de) * | 1990-09-25 | 1997-06-12 | Allergan, Inc., Irvine, Calif. | Vorrichtung und verfahren zur desinfektion von kontaktlinsen und ermittlung der anwesenheit eines oxidativen desinfektionsmittels |
| US5129999A (en) * | 1990-10-04 | 1992-07-14 | Allergan, Inc. | Lens disinfector and method |
| US5180517A (en) * | 1990-11-05 | 1993-01-19 | United States Borax & Chemical Corporation | Stabilized liquid persalt bleach compositions |
| IT1243946B (it) * | 1990-11-29 | 1994-06-28 | Zeiss Carl Spa | Metodo per la disinfezione e la detersione di lenti a contatto. |
| WO1992011042A1 (en) * | 1990-12-19 | 1992-07-09 | Allergan, Inc. | Compositions and methods for contact lens disinfecting |
| US5145644A (en) * | 1990-12-20 | 1992-09-08 | Allergan, Inc. | Hydrogen peroxide destroying compositions and methods of making and using same |
| US5209783A (en) * | 1990-12-21 | 1993-05-11 | Allergan, Inc. | Method for simultaneously cleaning, decolorizing and thermally disinfecting contact lenses |
| US5523012A (en) * | 1991-07-19 | 1996-06-04 | Ciba-Geigy Corporation | Hydrogen peroxide disinfection solutions |
| NZ243749A (en) * | 1991-08-30 | 1994-11-25 | Allergan Inc | Composition for neutralising and indicating the absence of peroxide comprising a neutralising compound and vitamin b-12 |
| US5270002A (en) * | 1991-10-03 | 1993-12-14 | Allergan, Inc. | Apparatus and method useful in disinfecting contact lenses |
| US5169455A (en) * | 1991-10-04 | 1992-12-08 | Kessler Jack H | Method for simultaneously cleaning and disinfecting contact lenses |
| EP0542686A1 (en) * | 1991-11-13 | 1993-05-19 | Ciba-Geigy Ag | Method and container for sterilizing or disinfecting |
| US5197636A (en) * | 1992-02-03 | 1993-03-30 | Allergan, Inc. | Fast activation chlorine dioxide delivery apparatus |
| US5719100A (en) * | 1992-03-20 | 1998-02-17 | Zahradnik; Rudolf | Water treatment compositions |
| AU677638B2 (en) | 1993-01-26 | 1997-05-01 | Allergan, Inc. | Compositions and methods to disinfect contact lenses |
| US5736165A (en) * | 1993-05-25 | 1998-04-07 | Allergan | In-the-eye use of chlorine dioxide-containing compositions |
| US5648074A (en) * | 1993-05-25 | 1997-07-15 | Allergan | Compositions and methods for disinfecting contact lenses and reducing proteinaceous deposit formation |
| US5447650A (en) * | 1993-10-06 | 1995-09-05 | Allergan, Inc. | Composition for preventing the accumulation of inorganic deposits on contact lenses |
| US5451237A (en) * | 1993-11-10 | 1995-09-19 | Vehige; Joseph G. | Compositions and methods for inhibiting and reducing lysozyme deposition on hydrophilic contact lenses using biocompatible colored compounds |
| US5494817A (en) * | 1993-12-06 | 1996-02-27 | Allergan, Inc. | Sugar-based protease composition for use with constant-PH borate buffers |
| US5603897A (en) * | 1994-06-30 | 1997-02-18 | Bausch & Lomb Incorporated | Method for indicating neutralization of contact lens disinfecting solutions |
| US6024954A (en) * | 1994-12-12 | 2000-02-15 | Allergan | Compositions and methods for disinfecting contact lenses and preserving contact lens care products |
| US5703024A (en) * | 1995-06-30 | 1997-12-30 | Allergan | Compositions and methods for disinfecting a contact lens and detecting the presence of an oxidative disinfectant |
| ES2178200T3 (es) * | 1997-02-28 | 2002-12-16 | Albert Sturm | Conservante para lentes de contacto, solido y soluble en agua. |
| US5928948A (en) * | 1997-03-10 | 1999-07-27 | Steris Corporation | Method for the assessment and validation of cleaning processes |
| US6099800A (en) * | 1998-08-14 | 2000-08-08 | Sinphar Pharmaceutical Co., Ltd. | Process for cleaning and disinfecting contact lens and hydrogen peroxide destroying composition having a delayed release function for use therein |
| FR2799651B1 (fr) * | 1999-10-14 | 2003-02-07 | Sanofi Elf | Comprime effervescent pour le reperage d'animaux sous traitement, procede de fabrication correspondant, et procede de traitement d'une solution aqueuse |
| US6790411B1 (en) * | 1999-12-02 | 2004-09-14 | 3M Innovative Properties Company | Hydrogen peroxide indicator and method |
| ES2190319B1 (es) * | 2000-12-01 | 2004-06-16 | Laboratorios Natysal, S.A. | Metodo para desinfeccion y neutralizacion conjunta de materiales y elementos, especialmente lentes de contacto. |
| JP2002212013A (ja) * | 2001-01-19 | 2002-07-31 | Mitsubishi Gas Chem Co Inc | 過酸化尿素錠剤及びその製造方法 |
| US6887496B2 (en) * | 2001-12-20 | 2005-05-03 | Kimberly-Clark Worldwide, Inc. | Products for controlling microbial organic compound production |
| US7192554B2 (en) * | 2001-12-31 | 2007-03-20 | 3M Innovative Properties Company | Hydrogen peroxide and peracetic acid indicators and methods |
| US20030220213A1 (en) * | 2002-05-24 | 2003-11-27 | Bober Andrew M. | Color changing floor finish stripper |
| US6737645B2 (en) | 2002-08-30 | 2004-05-18 | Tropicana Products, Inc. | Method for qualifying bottle rinser |
| US7105350B2 (en) | 2002-08-30 | 2006-09-12 | Tropicana Products, Inc. | Closure integrity test method for hot-fill bottling operation |
| US7186373B2 (en) * | 2003-07-22 | 2007-03-06 | Steris Inc. | Visual detector for vaporized hydrogen peroxide |
| JP5069293B2 (ja) * | 2006-07-13 | 2012-11-07 | ノバルティス アーゲー | レンズケア方法及びキット |
| DE102006062616A1 (de) * | 2006-12-29 | 2008-07-03 | Anovis Biotech Gmbh | Kontaktlinsenreiniger |
| US20080206874A1 (en) * | 2007-02-28 | 2008-08-28 | The Lubrizol Corporation | Analysis of Functional Fluids |
| US7850925B2 (en) * | 2007-06-15 | 2010-12-14 | American Sterilizer Company | Apparatus for removal of vaporized hydrogen peroxide from a region |
| US20090220618A1 (en) * | 2008-02-29 | 2009-09-03 | Erning Xia | Pharmaceutical formulations comprising polyanionic materials and source of hydrogen peroxide |
| US9481856B2 (en) * | 2008-06-09 | 2016-11-01 | Bausch & Lomb Incorporated | Pharmaceutical formulations comprising stabilized polysaccharides and source of hydrogen peroxide |
| US8932646B2 (en) * | 2010-06-18 | 2015-01-13 | Bausch & Lomb Incorporated | Peroxide contact lens care solution |
| US8785360B1 (en) * | 2010-08-14 | 2014-07-22 | Ian Herrick | Method and system for color changing contact lens solution |
| US9622911B2 (en) | 2010-09-30 | 2017-04-18 | Cxl Ophthalmics, Llc | Ophthalmic treatment device, system, and method of use |
| MY164100A (en) | 2011-12-31 | 2017-11-30 | Novartis Ag | Method of making contact lenses with identifying mark |
| WO2013148895A1 (en) | 2012-03-29 | 2013-10-03 | Cxl Ophthalmics, Llc | Ocular cross-linking system and method for sealing corneal wounds |
| ES2986057T3 (es) | 2012-03-29 | 2024-11-08 | Epion Therapeutics Inc | Composiciones y métodos para tratar o prevenir enfermedades asociadas al estrés oxidativo |
| EP2830627B1 (en) | 2012-03-29 | 2024-05-01 | Epion Therapeutics, Inc. | Ocular treatment solutions, delivery devices and delivery augmentation methods |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE612158A (sv) * | 1961-08-07 | |||
| US3243377A (en) * | 1963-08-30 | 1966-03-29 | Warner Lambert Pharmaceutical | Denture cleansing composition |
| US3843557A (en) * | 1971-10-05 | 1974-10-22 | Mennen Co Inc | Microcapsules and method of making same |
| GB1423147A (en) * | 1972-09-13 | 1976-01-28 | Howard E R Ltd | Device for dispensing soluble materials into flushing toilets |
| DK137366B (da) * | 1974-01-07 | 1978-02-27 | Nat Patent Dev Corp | Fremgangsmåde og middel til sterilisering af hydrofile kontaktlinser. |
| US4016089A (en) * | 1974-11-11 | 1977-04-05 | Regan Glen B | Denture cleaning concentrate |
| US4115293A (en) * | 1975-10-06 | 1978-09-19 | E. I. Du Pont De Nemours And Company | Denture cleanser |
| US4295985A (en) * | 1979-10-25 | 1981-10-20 | Petrow Henry G | Method of removal of chlorine retained by human skin and hair after exposure to chlorinated water, and soap and shampoo compositions adapted to effect said removal |
| US4668475A (en) * | 1982-04-02 | 1987-05-26 | Twinoak Products, Inc. | Cleaning and disinfecting method and article of manufacture including color display |
| FR2544880B1 (fr) * | 1983-04-20 | 1986-08-29 | Pos Lab | Procede pour le nettoyage et la decontamination de lentilles de contact et composition pour sa mise en oeuvre |
| US4568517A (en) * | 1983-08-25 | 1986-02-04 | Barnes-Hind, Inc. | Disinfection of contact lenses |
| GB8332489D0 (en) * | 1983-12-06 | 1984-01-11 | Contactasol Ltd | Contact lenses |
| GB8515079D0 (en) * | 1985-06-14 | 1985-07-17 | Kellway Pharma | Contact lens cleaning & disinfection |
| DE3666914D1 (en) * | 1985-07-10 | 1989-12-21 | Ciba Geigy Ag | Cleaning set for contact lenses |
| US4670178A (en) * | 1985-09-09 | 1987-06-02 | Allergan Pharmaceuticals, Inc. | Method for the simultaneous cleaning and disinfecting of contact lenses |
-
1985
- 1985-03-25 GB GB858507678A patent/GB8507678D0/en active Pending
-
1986
- 1986-03-24 WO PCT/GB1986/000168 patent/WO1986005695A1/en not_active Ceased
- 1986-03-24 AU AU56627/86A patent/AU584189B2/en not_active Ceased
- 1986-03-24 BR BR8607091A patent/BR8607091A/pt not_active Application Discontinuation
- 1986-03-24 DE DE8686901961T patent/DE3675018D1/de not_active Expired - Lifetime
- 1986-03-24 GB GB08607243A patent/GB2173017B/en not_active Expired
- 1986-03-24 EP EP86901961A patent/EP0250427B1/en not_active Expired - Lifetime
- 1986-03-24 JP JP61501825A patent/JPH0677597B2/ja not_active Expired - Lifetime
- 1986-03-24 US US06/946,572 patent/US4863627A/en not_active Expired - Fee Related
- 1986-03-24 HU HU863005A patent/HU198845B/hu not_active IP Right Cessation
- 1986-11-25 DK DK566686A patent/DK165818C/da not_active IP Right Cessation
-
1987
- 1987-09-24 FI FI874192A patent/FI85553C/sv not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| FI874192L (fi) | 1987-09-24 |
| HU198845B (en) | 1989-12-28 |
| DK566686D0 (da) | 1986-11-25 |
| DK566686A (da) | 1986-11-25 |
| EP0250427A1 (en) | 1988-01-07 |
| HUT46239A (en) | 1988-10-28 |
| GB2173017A (en) | 1986-10-01 |
| BR8607091A (pt) | 1988-01-19 |
| DK165818C (da) | 1993-06-21 |
| DE3675018D1 (de) | 1990-11-22 |
| AU5662786A (en) | 1986-10-23 |
| WO1986005695A1 (en) | 1986-10-09 |
| US4863627A (en) | 1989-09-05 |
| GB8607243D0 (en) | 1986-04-30 |
| EP0250427B1 (en) | 1990-10-17 |
| FI85553C (sv) | 1992-05-11 |
| GB2173017B (en) | 1988-11-02 |
| DK165818B (da) | 1993-01-25 |
| GB8507678D0 (en) | 1985-05-01 |
| JPS62502245A (ja) | 1987-09-03 |
| AU584189B2 (en) | 1989-05-18 |
| JPH0677597B2 (ja) | 1994-10-05 |
| FI874192A0 (fi) | 1987-09-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM | Patent lapsed | ||
| MM | Patent lapsed |
Owner name: UNIVERSITY OF BATH |