CA2044072A1 - Method of disinfection of soft contact lenses - Google Patents
Method of disinfection of soft contact lensesInfo
- Publication number
- CA2044072A1 CA2044072A1 CA 2044072 CA2044072A CA2044072A1 CA 2044072 A1 CA2044072 A1 CA 2044072A1 CA 2044072 CA2044072 CA 2044072 CA 2044072 A CA2044072 A CA 2044072A CA 2044072 A1 CA2044072 A1 CA 2044072A1
- Authority
- CA
- Canada
- Prior art keywords
- contact lenses
- disinfection
- chloramine
- amount
- soft
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Landscapes
- Apparatus For Disinfection Or Sterilisation (AREA)
Abstract
METHOD OF DISINFECTION OF SOFT CONTACT LENSES
Abstract of the Disclosure The invention provides a method of disinfecting soft, hydrophilic contact lenses comprising immersing, for a period of time sufficient to result in disinfection, the contact lenses in a solution containing a small but effec-tive amount of chloramine-T in concentration effective for disinfection but non-damaging to the eye and to the contact lenses, wherein the amount of chlorine released by the chloramine-T is from 2 to 250 parts per million.
Abstract of the Disclosure The invention provides a method of disinfecting soft, hydrophilic contact lenses comprising immersing, for a period of time sufficient to result in disinfection, the contact lenses in a solution containing a small but effec-tive amount of chloramine-T in concentration effective for disinfection but non-damaging to the eye and to the contact lenses, wherein the amount of chlorine released by the chloramine-T is from 2 to 250 parts per million.
Description
2 0 ~ 7 2 METHOD OF DI8INFECTION OF 80FT CONTAC N8~B
Field_of the Invention The present invention relates to methods of disinfection of soft contact lenses.
Background of the Invention Most contact lenses currently sold and used are hydrophilic or soft contact lenses, as opposed to hydro-phobic or hard lenses, due to the improved comfort of the user of such lenses and reduced irritation of the eye.
However by their nature, it is necessary to maintain such lS hydrophilic lenses in a sterile condition. Any sterilizing agent used must kill the bacteria on and in the lens, be harmless to the eye and have no effect on the shape or material of the lens.
Various substances have been used for steriliz-ation of contact lenses. Most involve substances whichrelease halogens, in particular chlorine, when dissolved in water. For example Canadian Patent No. 1,003,749 issued January 18, 1977 to Hydrophilics International, Inc.
discloses the use of sodium dichlorocyanurate, chlorinated trisodium phosphate, potassium dichlorocyanurate an tri-chloroisocyanuric acid in solution to sterilize soft contact lenses. Other methods involve the use of hydrogen peroxide as a sterilizing agent. Improper disinfecting agents can alter the shape of the contact lens which renders them useless.
Chloro-para-toluenesulfonamide-tosylchloramidum-natricum (hereinafter "chloramine-T") is a mild disinfec-tant used in such applications as the purification of water. It is sold generally in powder form. It releases chlorine upon dissolution in water. It has not been applied however to contact lens disinfection.
2~Q7~
Summary of the Invention The invention provides a method of disinfecting soft, hydrophilic contact lenses comprising immersing, for a period of time sufficient to result in disinfection, the contact lenses in a solution containing a small but effec-tive amount of chloramine-T in concentration effective for disinfection but non-damaging to the eye and to the contact lenses, wherein the amount of chlorine released by the chloramine-T is from 2 to 250 parts per million.
Detai~çd Description of the Preferred Embodiment According to the invention, a contact lens disinfectant solution is prepared by dissolving a suffi-cient amount of chloramine-T in water to produce between 2 and 250 parts per million of chlorine in the water. The soft, hydrophilic contact lenses are immersed, for a period of time sufficient to result in disinfection, in the solution, which is effective for disinfection but non-damaging to the eye and to the contact lenses. Sodium bicarbonate may be added to the chloramine-T preparation to neutralize the pH of the remaining solution on the contact lenses.
; EXAMPLE
By way of example, a solution is prepared by adding 0.1 milligrams of chloramine-T in powdered form to 10 ml. of water. Approximately 10 parts per million of chlorine is produced in the water. A soft contact lens is immersed in the solution for 1.5 hours. The amounts of living bacteria on the lens after removal are found to be minimal, and there is no detected alteration of the lens shape or material.
.~ .
, - 3 - 2~Q~
As will be apparent to those skilled in the art in the light of the foregoing disclosure, many alterations and modifications are possible in the practice of this invention without departing from the spirit or scope S thereof. Accordingly, the scope of the invention is to be construed in accordance with the substance defined by the following claims.
Field_of the Invention The present invention relates to methods of disinfection of soft contact lenses.
Background of the Invention Most contact lenses currently sold and used are hydrophilic or soft contact lenses, as opposed to hydro-phobic or hard lenses, due to the improved comfort of the user of such lenses and reduced irritation of the eye.
However by their nature, it is necessary to maintain such lS hydrophilic lenses in a sterile condition. Any sterilizing agent used must kill the bacteria on and in the lens, be harmless to the eye and have no effect on the shape or material of the lens.
Various substances have been used for steriliz-ation of contact lenses. Most involve substances whichrelease halogens, in particular chlorine, when dissolved in water. For example Canadian Patent No. 1,003,749 issued January 18, 1977 to Hydrophilics International, Inc.
discloses the use of sodium dichlorocyanurate, chlorinated trisodium phosphate, potassium dichlorocyanurate an tri-chloroisocyanuric acid in solution to sterilize soft contact lenses. Other methods involve the use of hydrogen peroxide as a sterilizing agent. Improper disinfecting agents can alter the shape of the contact lens which renders them useless.
Chloro-para-toluenesulfonamide-tosylchloramidum-natricum (hereinafter "chloramine-T") is a mild disinfec-tant used in such applications as the purification of water. It is sold generally in powder form. It releases chlorine upon dissolution in water. It has not been applied however to contact lens disinfection.
2~Q7~
Summary of the Invention The invention provides a method of disinfecting soft, hydrophilic contact lenses comprising immersing, for a period of time sufficient to result in disinfection, the contact lenses in a solution containing a small but effec-tive amount of chloramine-T in concentration effective for disinfection but non-damaging to the eye and to the contact lenses, wherein the amount of chlorine released by the chloramine-T is from 2 to 250 parts per million.
Detai~çd Description of the Preferred Embodiment According to the invention, a contact lens disinfectant solution is prepared by dissolving a suffi-cient amount of chloramine-T in water to produce between 2 and 250 parts per million of chlorine in the water. The soft, hydrophilic contact lenses are immersed, for a period of time sufficient to result in disinfection, in the solution, which is effective for disinfection but non-damaging to the eye and to the contact lenses. Sodium bicarbonate may be added to the chloramine-T preparation to neutralize the pH of the remaining solution on the contact lenses.
; EXAMPLE
By way of example, a solution is prepared by adding 0.1 milligrams of chloramine-T in powdered form to 10 ml. of water. Approximately 10 parts per million of chlorine is produced in the water. A soft contact lens is immersed in the solution for 1.5 hours. The amounts of living bacteria on the lens after removal are found to be minimal, and there is no detected alteration of the lens shape or material.
.~ .
, - 3 - 2~Q~
As will be apparent to those skilled in the art in the light of the foregoing disclosure, many alterations and modifications are possible in the practice of this invention without departing from the spirit or scope S thereof. Accordingly, the scope of the invention is to be construed in accordance with the substance defined by the following claims.
Claims (4)
1. A method of disinfecting soft, hydrophilic contact lenses comprising immersing, for a period of time sufficient to result in disinfection, the contact lenses in a solution containing a small but effective amount of chloramine-T in concentration effective for disinfection but non-damaging to the eye and to the contact lenses, wherein the amount of chlorine released by the chloramine-T is from 2 to 250 parts per million.
2. The method of claim 1 wherein said amount of chlorine is approximately 10 parts per million.
3. The method of claim 3 wherein said period of time is between 1 and 2 hours.
4. The method of claim 1 comprising the further step of adding sodium bicarbonate to the solution described in claim 1 in a quantity sufficient to neutralize said sol-ution.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA 2044072 CA2044072A1 (en) | 1991-06-07 | 1991-06-07 | Method of disinfection of soft contact lenses |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA 2044072 CA2044072A1 (en) | 1991-06-07 | 1991-06-07 | Method of disinfection of soft contact lenses |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2044072A1 true CA2044072A1 (en) | 1992-12-08 |
Family
ID=4147758
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA 2044072 Abandoned CA2044072A1 (en) | 1991-06-07 | 1991-06-07 | Method of disinfection of soft contact lenses |
Country Status (1)
| Country | Link |
|---|---|
| CA (1) | CA2044072A1 (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1996007324A1 (en) * | 1994-09-09 | 1996-03-14 | Novo Nordisk A/S | Cleaning, disinfecting and preserving contact lenses |
-
1991
- 1991-06-07 CA CA 2044072 patent/CA2044072A1/en not_active Abandoned
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1996007324A1 (en) * | 1994-09-09 | 1996-03-14 | Novo Nordisk A/S | Cleaning, disinfecting and preserving contact lenses |
| US5985629A (en) * | 1994-09-09 | 1999-11-16 | Novo Nordisk A/S | Cleaning and disinfecting contact lenses with a protease and chloramine-T or chloramine-B |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Dead |