FI854211A0 - Tricycliska pyridinderivat. - Google Patents

Tricycliska pyridinderivat.

Info

Publication number
FI854211A0
FI854211A0 FI854211A FI854211A FI854211A0 FI 854211 A0 FI854211 A0 FI 854211A0 FI 854211 A FI854211 A FI 854211A FI 854211 A FI854211 A FI 854211A FI 854211 A0 FI854211 A0 FI 854211A0
Authority
FI
Finland
Prior art keywords
tricycliska
pyridinderivat
tricycliska pyridinderivat
Prior art date
Application number
FI854211A
Other languages
English (en)
Other versions
FI89049B (fi
FI89049C (fi
Inventor
Ulf Fischer
Fernand Schneider
Ulrich Widmer
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of FI854211A0 publication Critical patent/FI854211A0/fi
Publication of FI89049B publication Critical patent/FI89049B/fi
Application granted granted Critical
Publication of FI89049C publication Critical patent/FI89049C/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02Muscle relaxants, e.g. for tetanus or cramps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D205/00Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/04Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D455/00Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
    • C07D455/02Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing not further condensed quinolizine ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D455/00Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
    • C07D455/03Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
    • C07D455/04Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing a quinolizine ring system condensed with only one six-membered carbocyclic ring, e.g. julolidine
    • C07D455/06Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing a quinolizine ring system condensed with only one six-membered carbocyclic ring, e.g. julolidine containing benzo [a] quinolizine ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/12Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D495/14Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/12Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains three hetero rings
    • C07D513/14Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI854211A 1984-11-06 1985-10-28 Foerfarande foer framstaellning av terapeutiskt anvaendbara tricykliska pyridinderivat och mellanprodukter FI89049C (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CH530484 1984-11-06
CH530484 1984-11-06
CH383685 1985-09-05
CH383685 1985-09-05

Publications (3)

Publication Number Publication Date
FI854211A0 true FI854211A0 (fi) 1985-10-28
FI89049B FI89049B (fi) 1993-04-30
FI89049C FI89049C (fi) 1993-08-10

Family

ID=25693960

Family Applications (1)

Application Number Title Priority Date Filing Date
FI854211A FI89049C (fi) 1984-11-06 1985-10-28 Foerfarande foer framstaellning av terapeutiskt anvaendbara tricykliska pyridinderivat och mellanprodukter

Country Status (23)

Country Link
US (2) US4735940A (fi)
EP (2) EP0318682B1 (fi)
JP (1) JPH0692405B2 (fi)
CN (1) CN1016871B (fi)
AR (1) AR242579A1 (fi)
AT (1) ATE51232T1 (fi)
AU (1) AU584132B2 (fi)
CA (1) CA1277659C (fi)
DE (2) DE3587235D1 (fi)
DK (1) DK507685A (fi)
DO (1) DOP1985004378A (fi)
ES (8) ES8705436A1 (fi)
FI (1) FI89049C (fi)
GB (1) GB2169288B (fi)
HU (1) HU205353B (fi)
IE (1) IE58850B1 (fi)
IL (1) IL76894A (fi)
IS (1) IS1469B6 (fi)
MC (1) MC1707A1 (fi)
MY (1) MY103172A (fi)
NO (1) NO171914C (fi)
PT (1) PT81431B (fi)
ZW (1) ZW17385A1 (fi)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4889848A (en) * 1984-11-06 1989-12-26 Hoffmann-La Roche Inc. Tricyclic pyridine derivatives
NO162285C (no) * 1984-11-23 1989-12-06 Fujisawa Pharmaceutical Co Analogifremgangsmaate for fremstilling av terapeutisk aktive kinolizinon-derivater.
CA1317945C (en) * 1985-12-13 1993-05-18 Ulf Fischer Tricyclic pyridazopyridone derivatives
EP0294599A3 (de) * 1987-06-12 1990-05-09 F. Hoffmann-La Roche Ag Tricyclische Pyridonderivate
DE69123090D1 (de) * 1990-07-06 1996-12-19 Yoshitomi Pharmaceutical Kondensierte Thiophenverbindungen und deren Verwendung
CA2058640A1 (en) * 1991-01-25 1992-07-26 Richard R. Scherschlicht Tricyclic pyridone derivative
US5532240A (en) * 1991-12-26 1996-07-02 Yoshitomi Pharmaceutical Industries, Ltd. Condensed thiophene compound and pharmaceutical use thereof
FR2689129B1 (fr) * 1992-03-27 1995-05-12 Atochem Elf Sa Nouveaux dérivés de l'acide 3-mercapto-2-thénoique et leurs procédés de préparation.
EP0650966A1 (de) * 1993-10-28 1995-05-03 F. Hoffmann-La Roche Ag Verfahren zur Herstellung eines Benzo(a)chinolizinon-Derivates
US5869500A (en) * 1996-12-13 1999-02-09 Hoffmann-La Roche Inc. Pyridone compounds useful in treating Alzheimer's disease
GB9708945D0 (en) * 1997-05-01 1997-06-25 Merck Sharp & Dohme Therapeutic agents
GB0119828D0 (en) * 2001-08-14 2001-10-10 Merck Sharp & Dohme Therapeutic agents
GB0119803D0 (en) * 2001-08-14 2001-10-10 Merck Sharp & Dohme Therapeutic agents
KR101421745B1 (ko) 2006-01-13 2014-07-22 더 트러스티스 오브 더 유니버시티 오브 펜실바니아 코돈 최적화된 il―15를 사용하는 백신 및 면역치료제, 및 그의 사용 방법
PL3041854T3 (pl) 2013-08-08 2020-06-29 The Scripps Research Institute Sposób miejscowo specyficznego oznakowania enzymatycznego kwasów nukleinowych in vitro przez inkorporację niewystępujących naturalnie nukleotydów

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MC1289A1 (fr) * 1978-10-13 1980-07-22 Hoffmann La Roche Phenyl quinolizidines
EP0067565A1 (en) * 1981-06-16 1982-12-22 Beecham Group Plc Pharmaceutically active compounds
GB8408292D0 (en) * 1984-03-30 1984-05-10 Fujisawa Pharmaceutical Co Quinolizinone compound
GB8420602D0 (en) * 1984-08-14 1984-09-19 Wyeth John & Brother Ltd Thienoquinolizines
NO162285C (no) * 1984-11-23 1989-12-06 Fujisawa Pharmaceutical Co Analogifremgangsmaate for fremstilling av terapeutisk aktive kinolizinon-derivater.
GB8509435D0 (en) * 1985-04-12 1985-05-15 Beecham Group Plc Intermediates & process
AU582663B2 (en) * 1985-08-10 1989-04-06 John Wyeth & Brother Limited Sulphonamides
US4686226A (en) * 1985-09-03 1987-08-11 Merck & Co., Inc. Substituted benzo[b]furo- and benzo[b]thieno quinolizines

Also Published As

Publication number Publication date
IL76894A (en) 1989-06-30
ES8800939A1 (es) 1987-12-01
GB8527196D0 (en) 1985-12-11
GB2169288A (en) 1986-07-09
IS1469B6 (is) 1991-09-24
ES554428A0 (es) 1987-12-01
CA1277659C (en) 1990-12-11
ES8705436A1 (es) 1987-05-01
EP0318682B1 (de) 1993-03-31
EP0183994A1 (de) 1986-06-11
IS3054A7 (is) 1986-05-07
EP0318682A3 (en) 1989-08-16
US5036066A (en) 1991-07-30
DOP1985004378A (es) 1991-04-05
ES554432A0 (es) 1987-12-01
PT81431B (pt) 1988-03-03
ES8800935A1 (es) 1987-12-01
MY103172A (en) 1993-05-29
AU4924185A (en) 1986-05-15
HU205353B (en) 1992-04-28
ES548532A0 (es) 1987-05-01
NO171914C (no) 1993-05-19
FI89049B (fi) 1993-04-30
ES554431A0 (es) 1987-12-01
AU584132B2 (en) 1989-05-18
DE3576691D1 (de) 1990-04-26
JPH0692405B2 (ja) 1994-11-16
ES554429A0 (es) 1987-12-01
ES8800936A1 (es) 1987-12-01
ES8800933A1 (es) 1987-12-01
CN1016871B (zh) 1992-06-03
CN85108120A (zh) 1986-11-05
ES554427A0 (es) 1987-12-01
IL76894A0 (en) 1986-02-28
AR242579A1 (es) 1993-04-30
NO171914B (no) 1993-02-08
JPS61115082A (ja) 1986-06-02
ES8800937A1 (es) 1987-12-01
PT81431A (en) 1985-12-01
NO854404L (no) 1986-05-07
ZW17385A1 (en) 1986-02-19
DK507685D0 (da) 1985-11-04
FI89049C (fi) 1993-08-10
ES8800934A1 (es) 1987-12-01
IE58850B1 (en) 1993-11-17
EP0318682A2 (de) 1989-06-07
ES8800932A1 (es) 1987-12-01
ATE51232T1 (de) 1990-04-15
EP0183994B1 (de) 1990-03-21
MC1707A1 (fr) 1986-09-22
HUT38638A (en) 1986-06-30
DE3587235D1 (en) 1993-05-06
ES554426A0 (es) 1987-12-01
GB2169288B (en) 1989-06-01
ES554430A0 (es) 1987-12-01
US4735940A (en) 1988-04-05
IE852751L (en) 1986-05-06
DK507685A (da) 1986-05-07

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Legal Events

Date Code Title Description
BB Publication of examined application
MM Patent lapsed
MM Patent lapsed

Owner name: F. HOFFMANN-LA ROCHE AG