FI853255L - Foerfarande foer framstaellning av 6-klor-n-metyl-2,3,4,5-tetrahydro-1h-3-bensazepin. - Google Patents
Foerfarande foer framstaellning av 6-klor-n-metyl-2,3,4,5-tetrahydro-1h-3-bensazepin.Info
- Publication number
- FI853255L FI853255L FI853255A FI853255A FI853255L FI 853255 L FI853255 L FI 853255L FI 853255 A FI853255 A FI 853255A FI 853255 A FI853255 A FI 853255A FI 853255 L FI853255 L FI 853255L
- Authority
- FI
- Finland
- Prior art keywords
- bensazepine
- framstaellning
- tetrahydro
- chloro
- methyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/16—Benzazepines; Hydrogenated benzazepines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/647,552 US4541954A (en) | 1984-09-05 | 1984-09-05 | Method for preparing 6-chloro-N-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| FI853255A0 FI853255A0 (fi) | 1985-08-23 |
| FI853255A7 FI853255A7 (fi) | 1986-03-06 |
| FI853255L true FI853255L (fi) | 1986-03-06 |
Family
ID=24597406
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI853255A FI853255L (fi) | 1984-09-05 | 1985-08-23 | Foerfarande foer framstaellning av 6-klor-n-metyl-2,3,4,5-tetrahydro-1h-3-bensazepin. |
Country Status (19)
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1993000811A1 (en) * | 1991-07-01 | 1993-01-21 | The General Hospital Corporation | Invertebrate phenylethanolamine transporter and the use thereof |
| WO1993011572A1 (fr) * | 1991-12-06 | 1993-06-10 | Yuasa Corporation | Pile mince et pile mince monolitique |
| US6953787B2 (en) | 2002-04-12 | 2005-10-11 | Arena Pharmaceuticals, Inc. | 5HT2C receptor modulators |
| US7704993B2 (en) | 2003-06-17 | 2010-04-27 | Arena Pharmaceuticals, Inc. | Benzazepine derivatives and methods of prophylaxis or treatment of 5ht2c receptor associated diseases |
| EA016485B1 (ru) * | 2003-06-17 | 2012-05-30 | Арена Фармасьютикалз, Инк. | Способы получения 3-бензазепинов |
| WO2006069363A2 (en) | 2004-12-21 | 2006-06-29 | Arena Pharmaceuticals, Inc. | Crystalline forms of (r)-8-chloro-1-methyl- 2,3,4,5-tetrahydro-1h-3-benzazepine hydrochloride |
| JP4886700B2 (ja) * | 2004-12-23 | 2012-02-29 | アリーナ ファーマシューティカルズ， インコーポレイテッド | ５ｈｔ２ｃレセプターモジュレーターの組成物およびその使用方法 |
| EP2471779A1 (en) | 2006-04-03 | 2012-07-04 | Arena Pharmaceuticals, Inc. | Process for the resolution of a mixture of (R)- and (S)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine |
| JP5404414B2 (ja) * | 2006-12-05 | 2014-01-29 | アリーナ ファーマシューティカルズ， インコーポレイテッド | （ｒ）−８−クロロ−１−メチル−２，３，４，５−テトラヒドロ−１ｈ−３−ベンゾアゼピンおよびその中間体を調製するための方法 |
| JP5491421B2 (ja) * | 2008-03-04 | 2014-05-14 | アリーナ ファーマシューティカルズ， インコーポレイテッド | ５−ｈｔ２ｃアゴニストである（ｒ）−８−クロロ−１−メチル−２，３，４，５−テトラヒドロ−１ｈ−３−ベンゾアゼピンに関連する中間体の調製のためのプロセス |
| EP2443080A2 (en) | 2009-06-18 | 2012-04-25 | Arena Pharmaceuticals, Inc. | Process for the preparation of 5-ht2c receptor agonists |
| KR20130112848A (ko) | 2010-06-02 | 2013-10-14 | 아레나 파마슈티칼스, 인크. | 5-ｈｔ2ｃ 수용체 아고니스트의 제조 방법 |
| CA2808912C (en) | 2010-09-01 | 2019-09-17 | Zezhi Jesse Shao | Modified-release dosage forms of 5-ht2c agonists useful for weight management |
| MX2013002418A (es) | 2010-09-01 | 2013-08-01 | Arena Pharm Inc | Administracion de lorcaserina a individuos con daño renal. |
| SG10201506865WA (en) | 2010-09-01 | 2015-10-29 | Arena Pharm Inc | Non-hygroscopic salts of 5-ht2c agonists |
| WO2012030938A1 (en) | 2010-09-01 | 2012-03-08 | Arena Pharmaceuticals, Inc. | Salts of lorcaserin with optically active acids |
| AR088670A1 (es) | 2012-10-09 | 2014-06-25 | Arena Pharm Inc | Metodo de control del peso |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1118688A (en) * | 1967-02-17 | 1968-07-03 | Scherico Ltd | Novel benzazepines and process for making same |
| CH481110A (de) * | 1967-02-17 | 1969-11-15 | Geigy Ag J R | Verfahren zur Herstellung von 1,2,4,5-Tetrahydro-3-azepinen |
| US4251660A (en) * | 1978-08-10 | 1981-02-17 | Smithkline Corporation | Method for preparing tetrahydroisoquinolines |
| US4200754A (en) * | 1979-02-02 | 1980-04-29 | Smithkline Corporation | Method for preparing 7,8-dichloro-1,2,3,4-tetrahydroisoquinoline |
| IE53962B1 (en) * | 1981-11-27 | 1989-04-26 | Smithkline Beckman Corp | 3-benzazepines as alpha-2 antagonists |
| ZA827887B (en) * | 1981-11-27 | 1983-11-30 | Smithkline Beckman Corp | Pharmaceutical compositions and method of producing alpha2 antagonism |
| DE3272044D1 (de) * | 1981-11-27 | 1986-08-21 | Smithkline Beckman Corp | 3-benzazepines as alpha-2 antagonists |
-
1984
- 1984-09-05 US US06/647,552 patent/US4541954A/en not_active Expired - Fee Related
-
1985
- 1985-08-14 EP EP85305780A patent/EP0174118A3/en not_active Ceased
- 1985-08-15 IL IL76100A patent/IL76100A0/xx unknown
- 1985-08-19 CA CA000488976A patent/CA1244017A/en not_active Expired
- 1985-08-19 ZA ZA856268A patent/ZA856268B/xx unknown
- 1985-08-19 NZ NZ213141A patent/NZ213141A/xx unknown
- 1985-08-19 PH PH32660A patent/PH20796A/en unknown
- 1985-08-19 NO NO853255A patent/NO853255L/no unknown
- 1985-08-20 JP JP60183788A patent/JPS6168469A/ja active Pending
- 1985-08-20 ES ES546285A patent/ES8609266A1/es not_active Expired
- 1985-08-20 ZW ZW133/85A patent/ZW13385A1/xx unknown
- 1985-08-21 AU AU46481/85A patent/AU581918B2/en not_active Ceased
- 1985-08-21 HU HU853190A patent/HU194181B/hu unknown
- 1985-08-21 DK DK379985A patent/DK379985A/da not_active Application Discontinuation
- 1985-08-22 KR KR1019850006061A patent/KR860002470A/ko not_active Withdrawn
- 1985-08-22 GR GR852041A patent/GR852041B/el unknown
- 1985-08-23 FI FI853255A patent/FI853255L/fi not_active Application Discontinuation
- 1985-08-23 PT PT81018A patent/PT81018B/pt unknown
- 1985-09-04 EG EG545/85A patent/EG17149A/xx active
Also Published As
| Publication number | Publication date |
|---|---|
| FI853255A0 (fi) | 1985-08-23 |
| HUT38617A (en) | 1986-06-30 |
| AU4648185A (en) | 1986-03-13 |
| PT81018B (en) | 1987-06-24 |
| NZ213141A (en) | 1988-07-28 |
| GR852041B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1985-12-19 |
| ES8609266A1 (es) | 1986-09-01 |
| DK379985D0 (da) | 1985-08-21 |
| EG17149A (en) | 1989-06-30 |
| PT81018A (en) | 1985-09-01 |
| FI853255A7 (fi) | 1986-03-06 |
| IL76100A0 (en) | 1985-12-31 |
| JPS6168469A (ja) | 1986-04-08 |
| DK379985A (da) | 1986-03-06 |
| ZA856268B (en) | 1986-07-30 |
| ES546285A0 (es) | 1986-09-01 |
| CA1244017A (en) | 1988-11-01 |
| AU581918B2 (en) | 1989-03-09 |
| NO853255L (no) | 1986-03-06 |
| EP0174118A2 (en) | 1986-03-12 |
| ZW13385A1 (en) | 1985-11-20 |
| PH20796A (en) | 1987-04-14 |
| US4541954A (en) | 1985-09-17 |
| EP0174118A3 (en) | 1986-12-30 |
| KR860002470A (ko) | 1986-04-26 |
| HU194181B (en) | 1988-01-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| FI853193L (fi) | Smaertstillande 1,2-benzisotiazol-3 -ylpiperazinderivat. | |
| FI854625L (fi) | Foerfarande foer framstaellning av pulverformigt, lineaert, basiskt polymerat. | |
| FI853255A0 (fi) | Foerfarande foer framstaellning av 6-klor-n-metyl-2,3,4,5-tetrahydro-1h-3-bensazepin. | |
| MX21592A (es) | 1,3-oxazolidin-2-ona. | |
| FI852765L (fi) | Foerfarande foer framstaellning av saosom hjaertmedicin anvaendbara 1,6-naftyridin 2(1h)-oner. | |
| FI852616L (fi) | Foerfarande foer uppvaermning av tjockvaeggiga glasroer, jaemte anordning. | |
| FI853837L (fi) | Foerfarande foer framstaellning av isolerande, poroesa, formade byggelement. | |
| FI853686L (fi) | Foerfarande foer framstaellning av 2,4 -diklor-5-fluorbensoesyra. | |
| FI852899L (fi) | Foerfarande foer framstaellning av fenylsubstituerade 2,4,6,8-nonatetraensyror. | |
| DE3585315D1 (de) | 5,6,7,8-tetrafluoranthrachinonderivate. | |
| FI841003L (fi) | Foerfarande foer framstaellning av staellningar, speciellt stegar. | |
| DE3586745D1 (de) | 9,11-epoxy-21-hydroxypregnan-derivate. | |
| FI853421A0 (fi) | 7-oxo-4-tia-1-azabicyklo/3,2,0/ hept-2-enderivat. | |
| FI853585A0 (fi) | Foerfarande foer framstaellning av aromatiska 1,4-oxazepinoner och -tioner. | |
| FI851520L (fi) | Anordning foer sammanpressning av en blaosfolieslang. | |
| FI855017L (fi) | Foerfarande foer framstaellning av 26,26,26-trifluor-1 ,25-dihydroxikolekalciferol. | |
| FI850604A0 (fi) | Anordning foer styckevis tvaermaetning av laongstraeckta foeremaol, foeretraedesvis virkesstycken. | |
| FI843270A0 (fi) | Foerfarande foer industriellt utnyttjande av till en tjocklek av 0,2-0,3 mm skuret traefaner. | |
| FI852372L (fi) | Foerfarande foer framstaellning av substituerade 1,3-dioxanderivat. | |
| FI902192A0 (fi) | Foerfarande foer framstaellning av 1,3-dihydro-4-pyridinyl-2h-imidazol-2-oner. | |
| FI850758A0 (fi) | Foerfarande foer framstaellning av 3-metyl-7-fluor-5-nitrobenzotiofen. | |
| FI841632A7 (fi) | Foerfarande foer framstaellning av laett instaellbara, haollbara anod- och jaernfoerelseelektrodkomponenter foer katodiskt skydd. | |
| FI850668A0 (fi) | Anordning foer behandling av roekgaser, speciellt avgaser. | |
| FI843391A7 (fi) | Foerfarande foer framstaellning av osymmetriska 1,4-dihydropyridin dikarboxylsyraestrar. | |
| FI842639A0 (fi) | Acylderivat av 1,4,3,6-dianhydro- hexitol. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD | Application lapsed |
Owner name: SMITHKLINE BECKMAN CORPORATION |