FI852956A0 - The method produces a novel human type I interferon protein - Google Patents

The method produces a novel human type I interferon protein

Info

Publication number
FI852956A0
FI852956A0 FI852956A FI852956A FI852956A0 FI 852956 A0 FI852956 A0 FI 852956A0 FI 852956 A FI852956 A FI 852956A FI 852956 A FI852956 A FI 852956A FI 852956 A0 FI852956 A0 FI 852956A0
Authority
FI
Finland
Prior art keywords
method produces
novel human
human type
interferon protein
interferon
Prior art date
Application number
FI852956A
Other languages
Finnish (fi)
Swedish (sv)
Other versions
FI90667B (en
FI852956L (en
FI90667C (en
Inventor
Rudolf Hauptmann
Peter Meindl
Eva Rastl-Dworkin
Guenther Adolf
Peter Swetly
Christian Pieler
Norbert Hauel
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE3428370A external-priority patent/DE3428370A1/en
Priority claimed from DE19853505060 external-priority patent/DE3505060A1/en
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of FI852956A0 publication Critical patent/FI852956A0/en
Publication of FI852956L publication Critical patent/FI852956L/en
Publication of FI90667B publication Critical patent/FI90667B/en
Application granted granted Critical
Publication of FI90667C publication Critical patent/FI90667C/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/56—IFN-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Abstract

The type I interferon peptides encoded by the genetic DNA sequences are called omega-interferons and are produced using appropriate expression vehicles and organisms.
FI852956A 1984-08-01 1985-07-31 The method produces a novel human type I interferon protein FI90667C (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE3428370 1984-08-01
DE3428370A DE3428370A1 (en) 1984-08-01 1984-08-01 Interferon, genetic sequences which code therefor, and organisms producing these
DE3505060 1985-02-14
DE19853505060 DE3505060A1 (en) 1985-02-14 1985-02-14 Type I interferons, genetic sequences which code therefor, and organisms producing these

Publications (4)

Publication Number Publication Date
FI852956A0 true FI852956A0 (en) 1985-07-31
FI852956L FI852956L (en) 1986-02-02
FI90667B FI90667B (en) 1993-11-30
FI90667C FI90667C (en) 1994-03-10

Family

ID=25823496

Family Applications (1)

Application Number Title Priority Date Filing Date
FI852956A FI90667C (en) 1984-08-01 1985-07-31 The method produces a novel human type I interferon protein

Country Status (21)

Country Link
EP (1) EP0170204B1 (en)
JP (2) JP2566909B2 (en)
KR (1) KR0136799B1 (en)
AT (1) ATE67786T1 (en)
AU (1) AU600653B2 (en)
BG (1) BG60445B2 (en)
CA (1) CA1340184C (en)
DD (1) DD246318A5 (en)
DE (1) DE3584198D1 (en)
DK (1) DK175194B1 (en)
ES (2) ES8609475A1 (en)
FI (1) FI90667C (en)
GR (1) GR851866B (en)
HK (1) HK187896A (en)
HU (1) HU205779B (en)
IE (1) IE58942B1 (en)
IL (1) IL75963A (en)
MX (1) MX9203645A (en)
NO (1) NO177863C (en)
NZ (1) NZ212937A (en)
PT (1) PT80901B (en)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5231176A (en) * 1984-08-27 1993-07-27 Genentech, Inc. Distinct family DNA encoding of human leukocyte interferons
EP0490233A1 (en) * 1986-03-10 1992-06-17 BOEHRINGER INGELHEIM INTERNATIONAL GmbH Monoclonal antibodies against Bgl III-hybrid interferons, their use and process for preparing them
DE3607835A1 (en) * 1986-03-10 1987-09-24 Boehringer Ingelheim Int HYBRID INTERFERONS, THEIR USE AS MEDICINAL PRODUCTS AND AS INTERMEDIATE PRODUCTS FOR THE PRODUCTION OF ANTIBODIES AND THE USE THEREOF AND METHOD FOR THEIR PRODUCTION
US4863727A (en) * 1986-04-09 1989-09-05 Cetus Corporation Combination therapy using interleukin-2 and tumor necrosis factor
DE3633323A1 (en) * 1986-10-01 1988-04-07 Boehringer Ingelheim Int NEW MONOCLONAL ANTIBODIES AGAINST IFN-OMEGA, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE FOR CLEANING AND DETECTING IFN-OMEGA
DE3635867A1 (en) * 1986-10-22 1988-05-11 Boehringer Ingelheim Int NEW YEAR EXPRESSION VECTORS FOR IFN-OMEGA, METHOD FOR THEIR PRODUCTION AND USE THEREOF
JP2001523480A (en) 1997-11-20 2001-11-27 バイカル インコーポレイテッド Treatment of cancer with cytokine-expressed polynucleotides and their compositions
WO2000040273A2 (en) * 1999-01-08 2000-07-13 Vical Incorporated Treatment of viral diseases using an interferon omega expressing polynucleotide
US20050287628A1 (en) 2002-03-07 2005-12-29 Markus Aebi System and method for the production of recombinant glycosylated proteins in a prokaryotic host
JP4727927B2 (en) * 2002-03-07 2011-07-20 アイトゲネシシェ・テッヒニシェ・ホーホシューレ・チューリッヒ Systems and methods for production of recombinant glycosylated proteins in prokaryotic hosts
US20070026485A1 (en) 2003-04-09 2007-02-01 Neose Technologies, Inc. Glycopegylation methods and proteins/peptides produced by the methods
WO2004096852A1 (en) * 2003-04-25 2004-11-11 The Institute Of Microbiology And Epidemiology, Academy Of Military Medical Sciemces, Pla A RECOMBINANT HUMAN INTERFERON ϖ, THE METHOD FOR EXPRESSING IT AND THE USES OF IT
DK2311972T3 (en) 2005-05-11 2015-04-27 Eth Zuerich Recombinant N-glycosylated proteins from prokaryotic cells
JP5782258B2 (en) 2008-02-20 2015-09-24 グリコヴァキシン アーゲー Bioconjugates made from prokaryotic recombinant N-glycosylated proteins
KR101855380B1 (en) 2009-11-19 2018-05-08 글락소스미스클라인 바이오로지칼즈 에스.에이. Biosynthetic system that produces immunogenic polysaccharides in prokaryotic cells
SG185433A1 (en) 2010-05-06 2012-12-28 Glycovaxyn Ag Capsular gram-positive bacteria bioconjugate vaccines
WO2013024156A2 (en) 2011-08-17 2013-02-21 INSERM (Institut National de la Santé et de la Recherche Médicale) Combinations of anti-hcv-entry factor antibodies and interferons for the treatment and the prevention of hcv infection
WO2013024158A1 (en) 2011-08-17 2013-02-21 INSERM (Institut National de la Santé et de la Recherche Médicale) Combinations of protein kinase inhibitors and interferons or of protein kinase inhibitors and direct acting antivirals for the treatment and the prevention of hcv infection
WO2014033266A1 (en) 2012-08-31 2014-03-06 INSERM (Institut National de la Santé et de la Recherche Médicale) Anti-sr-bi antibodies for the inhibition of hepatitis c virus infection

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1217440A (en) * 1982-08-18 1987-02-03 Michael A. Innis INTERFERON .alpha. 6L
AU1946283A (en) * 1982-08-18 1984-03-07 Cetus Corporation Interferon-alpha 6l
DE3247922A1 (en) * 1982-12-24 1984-06-28 Boehringer Ingelheim International GmbH, 6507 Ingelheim DNA SEQUENCES, THEIR PRODUCTION, PLASMIDES CONTAINING THESE SEQUENCES AND THE USE THEREOF FOR THE SYNTHESIS OF EUKARYOTIC GENE PRODUCTS IN PROKARYOTS
ATE47864T1 (en) * 1984-08-27 1989-11-15 Genentech Inc MISCELLANEOUS FAMILY OF HUMAN WBC INTERFERONS, COMPOSITIONS CONTAINING THEM, METHODS FOR THEIR PRODUCTION, AND DNA AND TRANSFECTED HOSTS THEREOF.

Also Published As

Publication number Publication date
EP0170204B1 (en) 1991-09-25
EP0170204A2 (en) 1986-02-05
EP0170204A3 (en) 1988-02-17
PT80901B (en) 1989-01-17
DK346385D0 (en) 1985-07-30
KR870001310A (en) 1987-03-13
IL75963A0 (en) 1985-12-31
PT80901A (en) 1985-09-01
ES545725A0 (en) 1986-08-01
HK187896A (en) 1996-10-18
ES552431A0 (en) 1987-09-01
HUT39477A (en) 1986-09-29
DK346385A (en) 1986-02-02
DK175194B1 (en) 2004-07-05
AU4554985A (en) 1986-02-06
AU600653B2 (en) 1990-08-23
JP2567195B2 (en) 1996-12-25
DD246318A5 (en) 1987-06-03
ES8708013A1 (en) 1987-09-01
CA1340184C (en) 1998-12-15
FI90667B (en) 1993-11-30
MX9203645A (en) 1992-09-01
JPS61181381A (en) 1986-08-14
JPH06181771A (en) 1994-07-05
BG60445B2 (en) 1995-03-31
ES8609475A1 (en) 1986-08-01
FI852956L (en) 1986-02-02
GR851866B (en) 1985-12-02
FI90667C (en) 1994-03-10
NZ212937A (en) 1991-08-27
NO853012L (en) 1986-02-03
NO177863C (en) 1995-12-06
KR0136799B1 (en) 1998-04-25
ATE67786T1 (en) 1991-10-15
JP2566909B2 (en) 1996-12-25
HU205779B (en) 1992-06-29
NO177863B (en) 1995-08-28
IL75963A (en) 1992-05-25
IE58942B1 (en) 1993-12-01
DE3584198D1 (en) 1991-10-31
IE851906L (en) 1986-02-01

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Legal Events

Date Code Title Description
BB Publication of examined application
FG Patent granted

Owner name: BOEHRINGER INGELHEIM INTERNATIONAL GMBH

MA Patent expired