FI762430A - - Google Patents

Info

Publication number
FI762430A
FI762430A FI762430A FI762430A FI762430A FI 762430 A FI762430 A FI 762430A FI 762430 A FI762430 A FI 762430A FI 762430 A FI762430 A FI 762430A FI 762430 A FI762430 A FI 762430A
Authority
FI
Finland
Application number
FI762430A
Other languages
Finnish (fi)
Inventor
Herbert Merz
Gerhard Walther
Adolf Langbein
Klaus Stockhaus
Helmut Wick
Original Assignee
Boehringer Sohn Ingelheim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim
Publication of FI762430A publication Critical patent/FI762430A/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D489/00Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/06Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with a hetero atom directly attached in position 14
    • C07D489/08Oxygen atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI762430A 1975-08-27 1976-08-24 FI762430A (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19752538075 DE2538075A1 (de) 1975-08-27 1975-08-27 N-tetrahydrofurfuryl-noroxymorphone, deren saeureadditionssalze, diese enthaltende arzneimittel sowie verfahren zu ihrer herstellung

Publications (1)

Publication Number Publication Date
FI762430A true FI762430A (ru) 1977-02-28

Family

ID=5954931

Family Applications (1)

Application Number Title Priority Date Filing Date
FI762430A FI762430A (ru) 1975-08-27 1976-08-24

Country Status (33)

Country Link
US (1) US4100288A (ru)
JP (1) JPS5231100A (ru)
AT (1) AT350737B (ru)
AU (1) AU499926B2 (ru)
BE (1) BE845563A (ru)
BG (2) BG27545A3 (ru)
CA (1) CA1068266A (ru)
CH (5) CH622521A5 (ru)
CS (2) CS192564B2 (ru)
DD (1) DD127145A5 (ru)
DE (1) DE2538075A1 (ru)
DK (1) DK143278C (ru)
ES (5) ES450897A1 (ru)
FI (1) FI762430A (ru)
FR (1) FR2321888A1 (ru)
GB (1) GB1519719A (ru)
GR (1) GR61158B (ru)
HU (1) HU176929B (ru)
IE (1) IE44069B1 (ru)
IL (1) IL50355A (ru)
LU (1) LU75667A1 (ru)
MX (1) MX4133E (ru)
NL (1) NL7609485A (ru)
NO (1) NO145793C (ru)
NZ (1) NZ181864A (ru)
PH (1) PH13780A (ru)
PL (2) PL110724B1 (ru)
PT (1) PT65521B (ru)
RO (1) RO69457A (ru)
SE (1) SE7609495L (ru)
SU (2) SU612631A3 (ru)
YU (1) YU208176A (ru)
ZA (1) ZA765120B (ru)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4272541A (en) * 1978-06-02 1981-06-09 Miles Laboratories, Inc. 7,8 and 7-8 Substituted 4,5α-epoxymorphinan-6-one compounds, and methods of treating pain and drug dependence with them
US4272540A (en) * 1979-04-24 1981-06-09 Sisa, Incorporated 14-Methoxymorphinan-6-one compounds and therapeutic methods of treating pain and drug dependence with them
DE3220831A1 (de) * 1982-06-03 1983-12-08 Boehringer Ingelheim KG, 6507 Ingelheim N-(2-methoxyethyl)-noroxymorphon, dessen saeureadditionssalze, diese enthaltende arzneimittel und verfahren zu deren herstellung
JP5586223B2 (ja) * 2006-04-21 2014-09-10 ネクター セラピューティクス モルヒノンの立体選択的還元
WO2012005795A1 (en) 2010-07-08 2012-01-12 Alkermes, Inc. Process for the synthesis of substituted morphinans
US9211293B2 (en) 2011-12-15 2015-12-15 Alkermes Pharma Ireland Limited Opioid agonist antagonist combinations
EP3003311A2 (en) 2013-05-24 2016-04-13 Alkermes Pharma Ireland Limited Methods for treating depressive symptoms
AU2014268361B2 (en) 2013-05-24 2018-09-06 Alkermes Pharma Ireland Limited Morphan and morphinan analogues, and methods of use
CN111836813A (zh) * 2018-02-23 2020-10-27 罗德科技公司 新型阿片样化合物及其用途
EP4243768A1 (en) 2020-11-12 2023-09-20 Alkermes Pharma Ireland Limited Immediate release multilayer tablet

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH446370A (de) 1964-03-05 1967-11-15 Hoffmann La Roche Verfahren zur Herstellung von Phenanthren-Derivaten
DE2238839A1 (de) * 1972-08-07 1974-02-14 Boehringer Sohn Ingelheim Neue morphinon-derivate, deren saeureadditionssalze, verfahren zu ihrer herstellung sowie ihre verwendung zur herstellung von arzneimitteln

Also Published As

Publication number Publication date
CH624115A5 (ru) 1981-07-15
ES454085A1 (es) 1977-11-16
DD127145A5 (ru) 1977-09-07
AU499926B2 (en) 1979-05-03
MX4133E (es) 1982-01-06
LU75667A1 (ru) 1977-09-13
PL110724B1 (en) 1980-07-31
GR61158B (en) 1978-09-30
DE2538075A1 (de) 1977-03-17
NO762932L (ru) 1977-03-01
IE44069B1 (en) 1981-08-12
NL7609485A (nl) 1977-03-01
ES454086A1 (es) 1977-11-16
CH624116A5 (ru) 1981-07-15
CS192599B2 (en) 1979-08-31
IL50355A0 (en) 1976-10-31
DK143278C (da) 1981-12-07
BE845563A (fr) 1977-02-28
JPS5231100A (en) 1977-03-09
NZ181864A (en) 1978-06-20
IL50355A (en) 1979-11-30
CS192564B2 (en) 1979-08-31
YU208176A (en) 1982-08-31
BG27546A4 (en) 1979-11-12
DK386876A (da) 1977-02-28
SE7609495L (sv) 1977-02-28
FR2321888B1 (ru) 1980-01-11
ES454087A2 (es) 1977-11-16
US4100288A (en) 1978-07-11
DK143278B (da) 1981-08-03
ZA765120B (en) 1978-05-30
FR2321888A1 (fr) 1977-03-25
ES454084A1 (es) 1977-11-16
PL192020A1 (pl) 1979-03-12
SU612631A3 (ru) 1978-06-25
SU638262A3 (ru) 1978-12-15
PH13780A (en) 1980-09-26
HU176929B (hu) 1981-06-28
PT65521A (de) 1976-09-01
ES450897A1 (es) 1977-12-01
CH622521A5 (ru) 1981-04-15
IE44069L (en) 1977-02-27
PT65521B (de) 1978-07-04
CH624117A5 (ru) 1981-07-15
BG27545A3 (en) 1979-11-12
GB1519719A (en) 1978-08-02
ATA553976A (de) 1978-11-15
CH624114A5 (ru) 1981-07-15
CA1068266A (en) 1979-12-18
PL109091B1 (en) 1980-05-31
AT350737B (de) 1979-06-11
NO145793C (no) 1982-06-02
RO69457A (ro) 1981-04-30
NO145793B (no) 1982-02-22
AU1720176A (en) 1978-03-02

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Legal Events

Date Code Title Description
FD Application lapsed

Owner name: C.H. BOEHRINGER SOHN