FI69082C - Foerfarande foer framstaellning av paromomycinderivat - Google Patents

Foerfarande foer framstaellning av paromomycinderivat Download PDF

Info

Publication number
FI69082C
FI69082C FI801769A FI801769A FI69082C FI 69082 C FI69082 C FI 69082C FI 801769 A FI801769 A FI 801769A FI 801769 A FI801769 A FI 801769A FI 69082 C FI69082 C FI 69082C
Authority
FI
Finland
Prior art keywords
benzoyl
deoxy
penta
paromomycin
acyl
Prior art date
Application number
FI801769A
Other languages
English (en)
Finnish (fi)
Other versions
FI69082B (fi
FI801769A (fi
Inventor
Carlo Battistini
Giuseppe Cassinelli
Giovanni Franceschi
Rosanna Mazzoleni
Federico Arcamone
Original Assignee
Erba Farmitalia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Farmitalia filed Critical Erba Farmitalia
Publication of FI801769A publication Critical patent/FI801769A/fi
Publication of FI69082B publication Critical patent/FI69082B/fi
Application granted granted Critical
Publication of FI69082C publication Critical patent/FI69082C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/228—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to adjacent ring-carbon atoms of the cyclohexane rings
    • C07H15/232—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to adjacent ring-carbon atoms of the cyclohexane rings with at least three saccharide radicals in the molecule, e.g. lividomycin, neomycin, paromomycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
FI801769A 1979-06-07 1980-06-02 Foerfarande foer framstaellning av paromomycinderivat FI69082C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB7919778 1979-06-07
GB7919778 1979-06-07

Publications (3)

Publication Number Publication Date
FI801769A FI801769A (fi) 1980-12-08
FI69082B FI69082B (fi) 1985-08-30
FI69082C true FI69082C (fi) 1985-12-10

Family

ID=10505676

Family Applications (1)

Application Number Title Priority Date Filing Date
FI801769A FI69082C (fi) 1979-06-07 1980-06-02 Foerfarande foer framstaellning av paromomycinderivat

Country Status (17)

Country Link
US (1) US4337248A (de)
EP (1) EP0021150B1 (de)
JP (1) JPS55164697A (de)
AT (1) ATE3429T1 (de)
AU (1) AU534470B2 (de)
BE (1) BE883686A (de)
CA (1) CA1137982A (de)
CS (1) CS226412B2 (de)
DE (1) DE3063288D1 (de)
DK (1) DK246180A (de)
FI (1) FI69082C (de)
FR (1) FR2458556A1 (de)
IE (1) IE50057B1 (de)
IL (1) IL60217A (de)
IT (1) IT1201934B (de)
SU (1) SU1103796A3 (de)
ZA (1) ZA803031B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5470836A (en) * 1988-04-29 1995-11-28 Farmitalia Carlo Erba S.R.L. Paromomycin or its derivatives or salts thereof in combination with sodium stirogluconate for parenteral treatment of human parasitic diseases
WO2004062674A2 (en) * 2003-01-07 2004-07-29 Paratek Pharmaceuticals, Inc. Substituted polyamines as inhibitors of bacterial efflux pumps
ES2707787T3 (es) 2005-12-02 2019-04-05 Ionis Pharmaceuticals Inc Análogos antibacterianos de aminoglucósido 4,5-sustituidos que tienen sustituyentes múltiples
US20080300199A1 (en) * 2007-04-10 2008-12-04 Achaogen Inc. Antibacterial 1,4,5-substituted aminoglycoside analogs
WO2010030704A2 (en) 2008-09-10 2010-03-18 Achaogen, Inc. Antibacterial aminoglycoside analogs
WO2010030690A1 (en) 2008-09-10 2010-03-18 Isis Pharmaceuticals, Inc. Antibacterial 4,6-substituted 6', 6" and 1 modified aminoglycoside analogs
WO2010042850A1 (en) 2008-10-09 2010-04-15 Achaogen, Inc. Antibacterial aminoglycoside analogs
WO2010042851A1 (en) 2008-10-09 2010-04-15 Achaogen, Inc. Antibacterial aminoglycoside analogs
EP2486044A2 (de) 2009-10-09 2012-08-15 Achaogen, Inc. Antibakterielle aminoglycosid-analoga
WO2011044538A1 (en) * 2009-10-09 2011-04-14 Achaogen, Inc. Antibacterial aminoglycoside analogs
AR083879A1 (es) 2010-11-17 2013-03-27 Achaogen Inc Analogos de aminoglicosidos antibacterianos, metodos de preparacion y uso como agentes terapeuticos

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3920628A (en) * 1972-10-24 1975-11-18 Schering Corp 2{41 -Deoxyaminoglycosides and 2{41 -epi-amino-3{41 -desamino derivatives thereof, methods for their manufacture and novel intermediates useful therein
SE402777C (sv) * 1972-12-29 1979-02-05 Takeda Chemical Industries Ltd Sett att framstella aminoglykosidantibiotika av 3'- och/eller 5''-dioxineomycintyp, 3'- och/eller 2''-dioxikanamycintyp eller 3''-dioxistryptomycintyp
US4051315A (en) * 1974-11-13 1977-09-27 Bristol-Myers Company 6"-Deoxykanamycin B and 6"-deoxytobramycin
JPS5850235B2 (ja) * 1974-12-11 1983-11-09 明治製菓株式会社 ３′，４′−α−エポキシ−リボスタマイシン又は−カナマイシンＢの製造法
US4247687A (en) * 1979-06-12 1981-01-27 Farmitalia Carlo Erba S.P.A. Aminoglycoside antibiotic derivatives and process for their preparation

Also Published As

Publication number Publication date
IT8022594A0 (it) 1980-06-06
AU5895580A (en) 1980-12-11
EP0021150A1 (de) 1981-01-07
JPS55164697A (en) 1980-12-22
FR2458556A1 (fr) 1981-01-02
DK246180A (da) 1980-12-08
CS226412B2 (en) 1984-03-19
IT1201934B (it) 1989-02-02
IL60217A (en) 1983-11-30
FI69082B (fi) 1985-08-30
AU534470B2 (en) 1984-02-02
FI801769A (fi) 1980-12-08
CA1137982A (en) 1982-12-21
DE3063288D1 (en) 1983-07-07
ZA803031B (en) 1981-05-27
IE50057B1 (en) 1986-02-05
EP0021150B1 (de) 1983-05-18
ATE3429T1 (de) 1983-06-15
IE801163L (en) 1980-12-07
IL60217A0 (en) 1980-09-16
FR2458556B1 (de) 1983-07-08
SU1103796A3 (ru) 1984-07-15
US4337248A (en) 1982-06-29
BE883686A (fr) 1980-12-08

Similar Documents

Publication Publication Date Title
US4331803A (en) Novel erythromycin compounds
FI69082C (fi) Foerfarande foer framstaellning av paromomycinderivat
DE2350169A1 (de) 1-n-( (s)-alpha-hydroxy-omegaaminoacyl)derivat von aminoglycosidischen antibioticas, verfahren zu ihrer herstellung und arzneipraeparate
US4837206A (en) Esperamicin derivatives
US4247687A (en) Aminoglycoside antibiotic derivatives and process for their preparation
US4066753A (en) Neomycin and paromomycin derivatives
EP0051280B1 (de) Anthracyclin-Glycoside, Verfahren zu ihrer Herstellung, Zwischenprodukte und ihre Herstellung und Arzneimittel
US4359583A (en) Antibiotics TM-531 B and TM-531 C
DK149775B (da) Analogifremgangsmaade til fremstilling af 6'-n-methylkanamycin a- og b-derivater
GB2068366A (en) A paromomycin derivative
US4486418A (en) 2'-Deamino aminoglycosides and composition thereof
US4131649A (en) Daunorubicin derivatives, their preparation and their use
DE3036172A1 (de) 2-desoxy-3-0-demethylfortimicine und diese verbindungen enthaltende arzneimittel
US4199571A (en) Substituted anthracyclines, their preparation and use
US4362866A (en) Aprosamine derivatives
US4353893A (en) Ka-6606 Aminoglycosides antibiotics and compositions thereof
Marconi et al. A32390A, a new biologically active metabolite II. Isolation and structure
US4125707A (en) Protected pseudotrisaccharide intermediate for paromomycin and neomycin derivatives
IE42285B1 (en) Butirosin a derivatives
GB2051798A (en) Paromomycin derivatives
US4132846A (en) 1-N-(α-Hydroxy-β-aminopropionyl) XK-62-2 and method of production thereof
US3941762A (en) O-acyl derivatives of antibiotic EM-49
US4482545A (en) Isoefrotomycin, process of preparation, pharmaceutical composition and method of using same
US4008218A (en) 1-N-((S)-α-substituted-ω-aminoacyl)-neamine or -ribostamycin and the production thereof
US4487924A (en) 2'-N-β-Lysyl) aminoglycosides

Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: FARMITALIA CARLO ERBA S.P.A.