DE3063288D1 - Paromomycin derivatives, a process for the preparation thereof and therapeutical composition containing them - Google Patents

Paromomycin derivatives, a process for the preparation thereof and therapeutical composition containing them

Info

Publication number
DE3063288D1
DE3063288D1 DE8080103089T DE3063288T DE3063288D1 DE 3063288 D1 DE3063288 D1 DE 3063288D1 DE 8080103089 T DE8080103089 T DE 8080103089T DE 3063288 T DE3063288 T DE 3063288T DE 3063288 D1 DE3063288 D1 DE 3063288D1
Authority
DE
Germany
Prior art keywords
derivatives
preparation
composition containing
paromomycin
therapeutical composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8080103089T
Other languages
English (en)
Inventor
Carlo Battistini
Giuseppe Cassinelli
Giovanni Franceschi
Rosanna Mazzoleni
Federico Arcamone
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Farmitalia Carlo Erba SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmitalia Carlo Erba SRL filed Critical Farmitalia Carlo Erba SRL
Application granted granted Critical
Publication of DE3063288D1 publication Critical patent/DE3063288D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/228—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to adjacent ring-carbon atoms of the cyclohexane rings
    • C07H15/232—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to adjacent ring-carbon atoms of the cyclohexane rings with at least three saccharide radicals in the molecule, e.g. lividomycin, neomycin, paromomycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE8080103089T 1979-06-07 1980-06-03 Paromomycin derivatives, a process for the preparation thereof and therapeutical composition containing them Expired DE3063288D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7919778 1979-06-07

Publications (1)

Publication Number Publication Date
DE3063288D1 true DE3063288D1 (en) 1983-07-07

Family

ID=10505676

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8080103089T Expired DE3063288D1 (en) 1979-06-07 1980-06-03 Paromomycin derivatives, a process for the preparation thereof and therapeutical composition containing them

Country Status (17)

Country Link
US (1) US4337248A (de)
EP (1) EP0021150B1 (de)
JP (1) JPS55164697A (de)
AT (1) ATE3429T1 (de)
AU (1) AU534470B2 (de)
BE (1) BE883686A (de)
CA (1) CA1137982A (de)
CS (1) CS226412B2 (de)
DE (1) DE3063288D1 (de)
DK (1) DK246180A (de)
FI (1) FI69082C (de)
FR (1) FR2458556A1 (de)
IE (1) IE50057B1 (de)
IL (1) IL60217A (de)
IT (1) IT1201934B (de)
SU (1) SU1103796A3 (de)
ZA (1) ZA803031B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5470836A (en) * 1988-04-29 1995-11-28 Farmitalia Carlo Erba S.R.L. Paromomycin or its derivatives or salts thereof in combination with sodium stirogluconate for parenteral treatment of human parasitic diseases
US7829543B2 (en) 2003-01-07 2010-11-09 Paratek Pharmaceuticals, Inc. Substituted polyamines as inhibitors of bacterial efflux pumps
ES2707787T3 (es) * 2005-12-02 2019-04-05 Ionis Pharmaceuticals Inc Análogos antibacterianos de aminoglucósido 4,5-sustituidos que tienen sustituyentes múltiples
WO2008124821A1 (en) 2007-04-10 2008-10-16 Achaogen Inc. Antibacterial 1,4,5-substituted aminoglycoside analogs
WO2010030704A2 (en) 2008-09-10 2010-03-18 Achaogen, Inc. Antibacterial aminoglycoside analogs
WO2010030690A1 (en) 2008-09-10 2010-03-18 Isis Pharmaceuticals, Inc. Antibacterial 4,6-substituted 6', 6" and 1 modified aminoglycoside analogs
WO2010042851A1 (en) 2008-10-09 2010-04-15 Achaogen, Inc. Antibacterial aminoglycoside analogs
WO2010042850A1 (en) 2008-10-09 2010-04-15 Achaogen, Inc. Antibacterial aminoglycoside analogs
CA2777107A1 (en) 2009-10-09 2011-04-14 Achaogen, Inc. Antibacterial aminoglycoside analogs
WO2011044538A1 (en) * 2009-10-09 2011-04-14 Achaogen, Inc. Antibacterial aminoglycoside analogs
TW201304784A (zh) 2010-11-17 2013-02-01 Achaogen Inc 抗菌性胺基糖苷類似物

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3920628A (en) * 1972-10-24 1975-11-18 Schering Corp 2{41 -Deoxyaminoglycosides and 2{41 -epi-amino-3{41 -desamino derivatives thereof, methods for their manufacture and novel intermediates useful therein
US4029883A (en) * 1972-12-29 1977-06-14 Takeda Chemical Industries, Ltd. Dehydroxylation of aminosugars
US4051315A (en) * 1974-11-13 1977-09-27 Bristol-Myers Company 6"-Deoxykanamycin B and 6"-deoxytobramycin
JPS5850235B2 (ja) * 1974-12-11 1983-11-09 明治製菓株式会社 ３′，４′−α−エポキシ−リボスタマイシン又は−カナマイシンＢの製造法
US4247687A (en) * 1979-06-12 1981-01-27 Farmitalia Carlo Erba S.P.A. Aminoglycoside antibiotic derivatives and process for their preparation

Also Published As

Publication number Publication date
FI69082B (fi) 1985-08-30
CA1137982A (en) 1982-12-21
FR2458556A1 (fr) 1981-01-02
FI69082C (fi) 1985-12-10
AU5895580A (en) 1980-12-11
IT8022594A0 (it) 1980-06-06
SU1103796A3 (ru) 1984-07-15
AU534470B2 (en) 1984-02-02
EP0021150B1 (de) 1983-05-18
IL60217A0 (en) 1980-09-16
DK246180A (da) 1980-12-08
IT1201934B (it) 1989-02-02
ZA803031B (en) 1981-05-27
BE883686A (fr) 1980-12-08
EP0021150A1 (de) 1981-01-07
JPS55164697A (en) 1980-12-22
IL60217A (en) 1983-11-30
IE50057B1 (en) 1986-02-05
IE801163L (en) 1980-12-07
US4337248A (en) 1982-06-29
FR2458556B1 (de) 1983-07-08
CS226412B2 (en) 1984-03-19
FI801769A (fi) 1980-12-08
ATE3429T1 (de) 1983-06-15

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Legal Events

Date Code Title Description
8339 Ceased/non-payment of the annual fee