ZA803031B - Paromomycin derivatives - Google Patents

Paromomycin derivatives

Info

Publication number
ZA803031B
ZA803031B ZA00803031A ZA803031A ZA803031B ZA 803031 B ZA803031 B ZA 803031B ZA 00803031 A ZA00803031 A ZA 00803031A ZA 803031 A ZA803031 A ZA 803031A ZA 803031 B ZA803031 B ZA 803031B
Authority
ZA
South Africa
Prior art keywords
derivatives
pharmaceutically acceptable
addition salts
paromomycin
paromomycin derivatives
Prior art date
Application number
ZA00803031A
Other languages
English (en)
Inventor
C Battistini
R Mazzoleni
G Cassinelli
F Arcamone
G Franceschi
Original Assignee
Erba Farmitalia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Farmitalia filed Critical Erba Farmitalia
Publication of ZA803031B publication Critical patent/ZA803031B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/228—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to adjacent ring-carbon atoms of the cyclohexane rings
    • C07H15/232—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to adjacent ring-carbon atoms of the cyclohexane rings with at least three saccharide radicals in the molecule, e.g. lividomycin, neomycin, paromomycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
ZA00803031A 1979-06-07 1980-05-21 Paromomycin derivatives ZA803031B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7919778 1979-06-07

Publications (1)

Publication Number Publication Date
ZA803031B true ZA803031B (en) 1981-05-27

Family

ID=10505676

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA00803031A ZA803031B (en) 1979-06-07 1980-05-21 Paromomycin derivatives

Country Status (17)

Country Link
US (1) US4337248A (xx)
EP (1) EP0021150B1 (xx)
JP (1) JPS55164697A (xx)
AT (1) ATE3429T1 (xx)
AU (1) AU534470B2 (xx)
BE (1) BE883686A (xx)
CA (1) CA1137982A (xx)
CS (1) CS226412B2 (xx)
DE (1) DE3063288D1 (xx)
DK (1) DK246180A (xx)
FI (1) FI69082C (xx)
FR (1) FR2458556A1 (xx)
IE (1) IE50057B1 (xx)
IL (1) IL60217A (xx)
IT (1) IT1201934B (xx)
SU (1) SU1103796A3 (xx)
ZA (1) ZA803031B (xx)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5470836A (en) * 1988-04-29 1995-11-28 Farmitalia Carlo Erba S.R.L. Paromomycin or its derivatives or salts thereof in combination with sodium stirogluconate for parenteral treatment of human parasitic diseases
WO2004062674A2 (en) * 2003-01-07 2004-07-29 Paratek Pharmaceuticals, Inc. Substituted polyamines as inhibitors of bacterial efflux pumps
ES2707787T3 (es) 2005-12-02 2019-04-05 Ionis Pharmaceuticals Inc Análogos antibacterianos de aminoglucósido 4,5-sustituidos que tienen sustituyentes múltiples
US20080300199A1 (en) * 2007-04-10 2008-12-04 Achaogen Inc. Antibacterial 1,4,5-substituted aminoglycoside analogs
WO2010030704A2 (en) 2008-09-10 2010-03-18 Achaogen, Inc. Antibacterial aminoglycoside analogs
WO2010030690A1 (en) 2008-09-10 2010-03-18 Isis Pharmaceuticals, Inc. Antibacterial 4,6-substituted 6', 6" and 1 modified aminoglycoside analogs
WO2010042850A1 (en) 2008-10-09 2010-04-15 Achaogen, Inc. Antibacterial aminoglycoside analogs
WO2010042851A1 (en) 2008-10-09 2010-04-15 Achaogen, Inc. Antibacterial aminoglycoside analogs
EP2486044A2 (en) 2009-10-09 2012-08-15 Achaogen, Inc. Antibacterial aminoglycoside analogs
WO2011044538A1 (en) * 2009-10-09 2011-04-14 Achaogen, Inc. Antibacterial aminoglycoside analogs
AR083879A1 (es) 2010-11-17 2013-03-27 Achaogen Inc Analogos de aminoglicosidos antibacterianos, metodos de preparacion y uso como agentes terapeuticos

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3920628A (en) * 1972-10-24 1975-11-18 Schering Corp 2{41 -Deoxyaminoglycosides and 2{41 -epi-amino-3{41 -desamino derivatives thereof, methods for their manufacture and novel intermediates useful therein
SE402777C (sv) * 1972-12-29 1979-02-05 Takeda Chemical Industries Ltd Sett att framstella aminoglykosidantibiotika av 3'- och/eller 5''-dioxineomycintyp, 3'- och/eller 2''-dioxikanamycintyp eller 3''-dioxistryptomycintyp
US4051315A (en) * 1974-11-13 1977-09-27 Bristol-Myers Company 6"-Deoxykanamycin B and 6"-deoxytobramycin
JPS5850235B2 (ja) * 1974-12-11 1983-11-09 明治製菓株式会社 ３′，４′−α−エポキシ−リボスタマイシン又は−カナマイシンＢの製造法
US4247687A (en) * 1979-06-12 1981-01-27 Farmitalia Carlo Erba S.P.A. Aminoglycoside antibiotic derivatives and process for their preparation

Also Published As

Publication number Publication date
IT8022594A0 (it) 1980-06-06
AU5895580A (en) 1980-12-11
EP0021150A1 (en) 1981-01-07
JPS55164697A (en) 1980-12-22
FR2458556A1 (fr) 1981-01-02
DK246180A (da) 1980-12-08
CS226412B2 (en) 1984-03-19
IT1201934B (it) 1989-02-02
IL60217A (en) 1983-11-30
FI69082B (fi) 1985-08-30
AU534470B2 (en) 1984-02-02
FI69082C (fi) 1985-12-10
FI801769A (fi) 1980-12-08
CA1137982A (en) 1982-12-21
DE3063288D1 (en) 1983-07-07
IE50057B1 (en) 1986-02-05
EP0021150B1 (en) 1983-05-18
ATE3429T1 (de) 1983-06-15
IE801163L (en) 1980-12-07
IL60217A0 (en) 1980-09-16
FR2458556B1 (xx) 1983-07-08
SU1103796A3 (ru) 1984-07-15
US4337248A (en) 1982-06-29
BE883686A (fr) 1980-12-08

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