FI68395C - Foerfarande foer framstaellning av farmakologiskt verksamma trazolfoereningar - Google Patents

Foerfarande foer framstaellning av farmakologiskt verksamma trazolfoereningar Download PDF

Info

Publication number
FI68395C
FI68395C FI800628A FI800628A FI68395C FI 68395 C FI68395 C FI 68395C FI 800628 A FI800628 A FI 800628A FI 800628 A FI800628 A FI 800628A FI 68395 C FI68395 C FI 68395C
Authority
FI
Finland
Prior art keywords
group
alkyl
formula
methyl
compound
Prior art date
Application number
FI800628A
Other languages
English (en)
Finnish (fi)
Other versions
FI800628A (fi
FI68395B (fi
Inventor
John Watson Clitherow
John Bradshaw
Barry John Price
Michael Martin-Smith
John Wilson Macfarla Mackinnon
Duncan Bruce Judd
Roger Hayes
Linda Carey
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of FI800628A publication Critical patent/FI800628A/fi
Application granted granted Critical
Publication of FI68395B publication Critical patent/FI68395B/fi
Publication of FI68395C publication Critical patent/FI68395C/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/101,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D249/14Nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/52Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/18Radicals substituted by singly bound oxygen or sulfur atoms
    • C07D317/22Radicals substituted by singly bound oxygen or sulfur atoms etherified
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/30Hetero atoms other than halogen
    • C07D333/36Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI800628A 1979-03-02 1980-02-29 Foerfarande foer framstaellning av farmakologiskt verksamma trazolfoereningar FI68395C (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB7907421 1979-03-02
GB7907421 1979-03-02
GB7907423 1979-03-02
GB7907423 1979-03-02

Publications (3)

Publication Number Publication Date
FI800628A FI800628A (fi) 1980-09-03
FI68395B FI68395B (fi) 1985-05-31
FI68395C true FI68395C (fi) 1985-09-10

Family

ID=26270755

Family Applications (1)

Application Number Title Priority Date Filing Date
FI800628A FI68395C (fi) 1979-03-02 1980-02-29 Foerfarande foer framstaellning av farmakologiskt verksamma trazolfoereningar

Country Status (15)

Country Link
EP (1) EP0016565B1 (es)
KR (2) KR850001319B1 (es)
AU (1) AU535701B2 (es)
CA (1) CA1159453A (es)
DE (1) DE3067920D1 (es)
DK (1) DK89480A (es)
ES (5) ES8105721A1 (es)
FI (1) FI68395C (es)
GB (1) GB2047238B (es)
IE (1) IE49528B1 (es)
IL (1) IL59503A (es)
NO (1) NO800583L (es)
NZ (1) NZ193009A (es)
PT (1) PT70884A (es)
YU (4) YU56680A (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2063874B (en) * 1979-10-22 1983-09-28 Glaxo Group Ltd Triazole derivatives processes for the preparation thereof and pharmaceutical compositions containing them
CH655104A5 (fr) * 1980-02-28 1986-03-27 Glaxo Group Ltd Derives heterocycliques triazoliques, procedes pour leur preparation et compositions pharmaceutiques les comportant.
GB2082584B (en) * 1980-08-27 1984-08-08 Glaxo Group Ltd Tetrazole derivatives
AU548426B2 (en) * 1980-08-27 1985-12-12 Glaxo Group Limited 3-amino-(1,2,4)-triazoles
US4439437A (en) * 1981-04-28 1984-03-27 Smith Kline & French Laboratories Limited 2-[2-Thiazolyl or 2-guanidino-4-thiazolyl methylthioethyl(or butyl)amino]-3-(hydroxy or carboxy)pyridines, compositions containing same and method of use
ES8307768A1 (es) * 1981-06-11 1983-08-01 Glaxo Group Ltd Un procedimiento para la preparacion de nuevos derivados de 1,2,4 triazol.
EP0070743A3 (en) * 1981-07-22 1983-10-12 Glaxo Group Limited Pharmaceutical compositions containing compounds having action on histamine receptors
BE894286A (fr) * 1981-09-04 1983-03-02 Glaxo Group Ltd Composition pharmaceutique contenant un medicament anti-inflammatoire systemique non steroidique et du 1-methyl-5-((3-(3-(1-piperidinylmethyl)phenoxy)-propyl)amino -1h-1,2,4-triazole-3-methanol ou un sel de ce compose
PT76280A (en) * 1982-02-24 1983-03-01 Glaxo Group Ltd Process for preparing heterocyclic derivatives
GB9009437D0 (en) * 1990-04-26 1990-06-20 Glaxo Group Ltd Chemical compounds
TWI697485B (zh) * 2015-07-21 2020-07-01 日商捷恩智股份有限公司 含唑啉環的化合物、含有其的電子輸送/注入層用材料、使用其的有機電致發光元件、顯示裝置及照明裝置

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3681374A (en) * 1970-08-11 1972-08-01 Asahi Chemical Ind Synthetic nacreous triazole crystals and method for production thereof
GB1403866A (en) * 1971-12-06 1975-08-28 Wyeth John & Brother Ltd Derivatives of 3-amino-1,2,4-triazoles
US4104381A (en) * 1973-05-03 1978-08-01 Smith Kline & French Laboratories Limited Pharmacologically active compounds
US4076938A (en) * 1974-08-29 1978-02-28 Ciba-Geigy Corporation Process for the production of 3-hydroxy-1,2,4-triazole derivatives
GB1547564A (en) * 1975-06-05 1979-06-20 Lilly Industries Ltd Acylated amino-heteroaryl compounds
GB1565966A (en) * 1976-08-04 1980-04-23 Allen & Hanburys Ltd Aminoalkyl furan derivatives
IE46886B1 (en) * 1977-05-17 1983-10-19 Allen & Hanburys Ltd Aminoalkyl-benzene derivatives
GB1601459A (en) * 1977-05-17 1981-10-28 Allen & Hanburys Ltd Aminoalkyl thiophene derivatives
AR228941A1 (es) * 1978-04-26 1983-05-13 Glaxo Group Ltd Procedimiento para preparar nuevos derivados de 3,5-diamino-1,2,4-triazol que son activos contra receptores histaminicos

Also Published As

Publication number Publication date
ES496487A0 (es) 1981-10-01
IE800410L (en) 1980-09-02
EP0016565A1 (en) 1980-10-01
DE3067920D1 (en) 1984-06-28
CA1159453A (en) 1983-12-27
FI800628A (fi) 1980-09-03
KR850001319B1 (en) 1985-09-14
YU277482A (en) 1983-04-30
ES496484A0 (es) 1981-10-01
IL59503A0 (en) 1980-05-30
YU277782A (en) 1983-04-30
YU277682A (en) 1983-04-30
ES489127A0 (es) 1981-05-16
YU56680A (en) 1983-04-30
KR830001911A (ko) 1983-05-19
KR850003289A (ko) 1985-06-13
ES8203857A1 (es) 1982-04-01
ES8107198A1 (es) 1981-10-01
GB2047238B (en) 1983-09-14
EP0016565B1 (en) 1984-05-23
ES496486A0 (es) 1981-10-01
GB2047238A (en) 1980-11-26
PT70884A (en) 1980-03-01
ES496485A0 (es) 1982-04-01
AU5604080A (en) 1980-09-04
NO800583L (no) 1980-09-03
ES8107199A1 (es) 1981-10-01
KR850001318B1 (ko) 1985-09-14
AU535701B2 (en) 1984-04-05
IL59503A (en) 1985-03-31
IE49528B1 (en) 1985-10-16
ES8105721A1 (es) 1981-05-16
ES8107200A1 (es) 1981-10-01
DK89480A (da) 1980-09-03
NZ193009A (en) 1983-07-15
FI68395B (fi) 1985-05-31

Similar Documents

Publication Publication Date Title
US4318913A (en) 1,2,4-Triazole-3,5-diamine derivatives
US7598279B2 (en) Neurotherapeutic azole compounds
EP0470514B1 (en) Carbostyril derivatives and pharmaceutical composition containing the same
US4904666A (en) Pyrazolo(3,4-d)pyrimidine compounds, compositions and method of use
CA2029275A1 (en) Aromatic amine compounds, their method of preparation and pharmaceutical compositions in which they are present
FI68395C (fi) Foerfarande foer framstaellning av farmakologiskt verksamma trazolfoereningar
AU2005268030A1 (en) Aromatic compounds
DE69704060T2 (de) Tetrahydroisochinolinderivate und ihre pharmazeutische anwendung
KR840000420B1 (ko) 헤로테고리 유도체의 제조방법
DE602006000102T2 (de) Indanyl-piperazinderivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zusammensetzungen
US4670448A (en) Triazole amine compounds, their pharmaceutical compositions and method of use
US4323566A (en) Triazole acylamines, pharmaceutical compositions thereof and method of use thereof
KR840001775B1 (ko) 헤테로 사이클릭 유도체의 제조방법
NL8005491A (nl) Heterocyclische verbindingen met therapeutische wer- king.
US4536508A (en) Triazoleamine derivatives having histamine H2 -antagonist properties
HU207845B (en) Process for producing butene-carboxylic acid derivatives and pharmaceutical compositions containing them
EP0029306A1 (en) Aminoalkyl compounds, their production and pharmaceutical compositions containing them
CA1192190A (en) Heterocyclic derivatives as histamine h in2- antagonists
US4476126A (en) 1,2,4 Triazoze amines and their pharmaceutical use
US4777179A (en) Heterocyclic derivatives, processes for the use thereof and pharmaceutical compositions containing them
KR840001773B1 (ko) 헤테로사이클릭 유도체의 제조방법
CA1188689A (en) 1,2,4-triazole derivatives as histamine h.sub.2- antagonists
HU185790B (en) Process for the preparation of new triazole derivatives
IE48750B1 (en) Heterocyclic derivatives
NO820384L (no) Fremgangsmaate for fremstilling av farmasoeytisk aktive tetrazolderivater.

Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: GLAXO GROUP LIMITED