FI68057C - Foerfarande foer framstaellning av antracyklinderivat - Google Patents

Foerfarande foer framstaellning av antracyklinderivat Download PDF

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Publication number
FI68057C
FI68057C FI800298A FI800298A FI68057C FI 68057 C FI68057 C FI 68057C FI 800298 A FI800298 A FI 800298A FI 800298 A FI800298 A FI 800298A FI 68057 C FI68057 C FI 68057C
Authority
FI
Finland
Prior art keywords
group
chloroform
adriamycin
derivative
formula
Prior art date
Application number
FI800298A
Other languages
English (en)
Finnish (fi)
Other versions
FI68057B (fi
FI800298A (fi
Inventor
Hamao Umezawa
Tomio Takeuchi
Hiroshi Naganawa
Kuniaki Tatsuta
Original Assignee
Microbial Chem Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP1170279A external-priority patent/JPS55104299A/ja
Priority claimed from JP11025579A external-priority patent/JPS5634695A/ja
Application filed by Microbial Chem Res Found filed Critical Microbial Chem Res Found
Publication of FI800298A publication Critical patent/FI800298A/fi
Publication of FI68057B publication Critical patent/FI68057B/fi
Application granted granted Critical
Publication of FI68057C publication Critical patent/FI68057C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FI800298A 1979-02-03 1980-02-01 Foerfarande foer framstaellning av antracyklinderivat FI68057C (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP1170279A JPS55104299A (en) 1979-02-03 1979-02-03 Anthracycline compounds and their preparation
JP1170279 1979-02-03
JP11025579 1979-08-31
JP11025579A JPS5634695A (en) 1979-08-31 1979-08-31 Novel anthracycline derivative and its preparation

Publications (3)

Publication Number Publication Date
FI800298A FI800298A (fi) 1980-08-04
FI68057B FI68057B (fi) 1985-03-29
FI68057C true FI68057C (fi) 1985-07-10

Family

ID=26347196

Family Applications (1)

Application Number Title Priority Date Filing Date
FI800298A FI68057C (fi) 1979-02-03 1980-02-01 Foerfarande foer framstaellning av antracyklinderivat

Country Status (11)

Country Link
EP (1) EP0014853B1 (fr)
AR (1) AR226694A1 (fr)
AT (1) AT369384B (fr)
AU (1) AU518278B2 (fr)
CA (1) CA1136618A (fr)
DE (1) DE3063557D1 (fr)
DK (1) DK160616C (fr)
ES (1) ES8101622A1 (fr)
FI (1) FI68057C (fr)
NZ (1) NZ192758A (fr)
PH (1) PH18200A (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56156300A (en) * 1980-04-26 1981-12-02 Microbial Chem Res Found Novel preparative method of anthracyclin derivative
JPS6016998A (ja) * 1983-07-07 1985-01-28 Microbial Chem Res Found アントラサイクリン誘導体の製造方法
GB2169284A (en) * 1985-01-05 1986-07-09 Erba Farmitalia 4'-Epidoxorubicin-14-esters
GB2169286A (en) * 1985-01-05 1986-07-09 Erba Farmitalia 4'-Deoxy-4'-halodoxorubicin-14-esters
GB2169285A (en) * 1985-01-05 1986-07-09 Erba Farmitalia 4'-Deoxydoxorubicin-14-esters
US4889926A (en) * 1987-06-12 1989-12-26 Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai Method for the synthesis of (2"R)-4'-O-tetra-hydropyranyladriamycim using 14-chloro-daunomycin as an intermediate
GB9026491D0 (en) * 1990-12-05 1991-01-23 Erba Carlo Spa Anthracycline-conjugates
US5776458A (en) * 1990-12-05 1998-07-07 Pharmacia & Upjohn S.P.A. Anthracycline-conjugates
IT1282379B1 (it) * 1996-04-24 1998-03-20 Mini Ricerca Scient Tecnolog Disaccaridi di antracicline antitumorali.
US8173621B2 (en) 2008-06-11 2012-05-08 Gilead Pharmasset Llc Nucleoside cyclicphosphates
MX2011006890A (es) 2008-12-23 2011-07-20 Pharmasset Inc Analogos de nucleosidos.
JP5793084B2 (ja) 2008-12-23 2015-10-14 ギリアド ファーマセット エルエルシー プリンヌクレオシドの合成
TW201026715A (en) 2008-12-23 2010-07-16 Pharmasset Inc Nucleoside phosphoramidates
PT2552930E (pt) 2010-03-31 2015-11-17 Gilead Pharmasset Llc 2-(((s)-(((2r,3r,4r,5r)-5-(2,4-dioxo-3,4-dihidropirimidin- 1-(2h)-il)-4-fluoro-3-hidroxi-4-metiltetrahidrofuran-2- il)metoxi) (fenoxi)fosforil)amino)propanoato de (s)- isopropilo cristalino

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS52148064A (en) * 1976-05-31 1977-12-08 Microbial Chem Res Found Antitumors
GB1561507A (en) * 1976-11-17 1980-02-20 Farmaceutici Italia Snthracycline disaccharides
JPS5430146A (en) * 1977-08-05 1979-03-06 Microbial Chem Res Found Novel anthracycline derivatives and their preparation

Also Published As

Publication number Publication date
EP0014853A1 (fr) 1980-09-03
AR226694A1 (es) 1982-08-13
ES488209A0 (es) 1980-12-16
CA1136618A (fr) 1982-11-30
DE3063557D1 (en) 1983-07-07
ES8101622A1 (es) 1980-12-16
FI68057B (fi) 1985-03-29
PH18200A (en) 1985-04-25
DK160616C (da) 1991-09-02
NZ192758A (en) 1982-03-09
AU518278B2 (en) 1981-09-24
AU5489580A (en) 1980-08-07
DK160616B (da) 1991-04-02
DK11480A (da) 1980-08-04
ATA51180A (de) 1982-05-15
FI800298A (fi) 1980-08-04
AT369384B (de) 1982-12-27
EP0014853B1 (fr) 1983-06-01

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Legal Events

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MM Patent lapsed
MM Patent lapsed

Owner name: ZAIDANHOJIN BISEIBUTSU KAGAKU KENKYUKAI