FI67551C - Foerfarande foer framstaellning av alfa-(2r)-2-((1r 5s)-3-substituerad 7-oxo-4-oxa-2,6-diazabicyclo(3.2.0)hept-2-en-6-yl)-3-metyl- och halogen-substituerad metyl-3-butensyraestrar for anvaendning som mellanprodukter vid framstaellning av 7 ala-metoxi-1-oxa-detiacefalosporiner - Google Patents

Foerfarande foer framstaellning av alfa-(2r)-2-((1r 5s)-3-substituerad 7-oxo-4-oxa-2,6-diazabicyclo(3.2.0)hept-2-en-6-yl)-3-metyl- och halogen-substituerad metyl-3-butensyraestrar for anvaendning som mellanprodukter vid framstaellning av 7 ala-metoxi-1-oxa-detiacefalosporiner Download PDF

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Publication number
FI67551C
FI67551C FI780059A FI780059A FI67551C FI 67551 C FI67551 C FI 67551C FI 780059 A FI780059 A FI 780059A FI 780059 A FI780059 A FI 780059A FI 67551 C FI67551 C FI 67551C
Authority
FI
Finland
Prior art keywords
methyl
oxa
substitutes
halogen
methoxy
Prior art date
Application number
FI780059A
Other languages
English (en)
Finnish (fi)
Other versions
FI780059A (fi
FI67551B (fi
Inventor
Yoshio Hamashima
Mitsuru Yoshioka
Shoichiro Uyeo
Teruji Tsuji
Ikuo Kikkawa
Wataru Nagata
Original Assignee
Shionogi & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP52001760A external-priority patent/JPS6040437B2/ja
Priority claimed from JP52036613A external-priority patent/JPS6019312B2/ja
Application filed by Shionogi & Co filed Critical Shionogi & Co
Publication of FI780059A publication Critical patent/FI780059A/fi
Priority to FI820013A priority Critical patent/FI68838C/fi
Priority to FI831571A priority patent/FI70712C/fi
Application granted granted Critical
Publication of FI67551B publication Critical patent/FI67551B/fi
Publication of FI67551C publication Critical patent/FI67551C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D505/00—Heterocyclic compounds containing 5-oxa-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/582—Recycling of unreacted starting or intermediate materials

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FI780059A 1977-01-10 1978-01-09 Foerfarande foer framstaellning av alfa-(2r)-2-((1r 5s)-3-substituerad 7-oxo-4-oxa-2,6-diazabicyclo(3.2.0)hept-2-en-6-yl)-3-metyl- och halogen-substituerad metyl-3-butensyraestrar for anvaendning som mellanprodukter vid framstaellning av 7 ala-metoxi-1-oxa-detiacefalosporiner FI67551C (fi)

Priority Applications (2)

Application Number Priority Date Filing Date Title
FI820013A FI68838C (fi) 1977-01-10 1982-01-05 Som mellanprodukt vid framstaellning av 7alfa-metoxi-1-oxadetiacefalosporiner anvaendbara (1r,5s)-7-oxo-4-oxa-2,6-diazabicyclo(3.2.0)hept-2-en-foereningar
FI831571A FI70712C (fi) 1977-01-10 1983-05-06 Som mellanprodukt vid framstaellning av 7beta-acylamino-7alfa-metoxi-1-oxadetiacefalosporiner anvaendbara 2-/7-oxo-3-substituerad-4-oxa-2,6-diazabicycdbara 2-/7-oxo-3- -substituerad-4-oxa-2,6-diazabicyclo/3.2.0/-hept-2-en-6-yl/-halogenmetyl- butensyrlo/3.2.0/-hept-2-en-6-yl/-halogenmetyl- butensyraderivat aderivat

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP52001760A JPS6040437B2 (ja) 1977-01-10 1977-01-10 オキサゾリノアゼチジン誘導体
JP176077 1977-01-10
JP3661377 1977-03-30
JP52036613A JPS6019312B2 (ja) 1977-03-30 1977-03-30 オキサゾリノアゼチジニルペンテン酸誘導体の製造法

Publications (3)

Publication Number Publication Date
FI780059A FI780059A (fi) 1978-07-11
FI67551B FI67551B (fi) 1984-12-31
FI67551C true FI67551C (fi) 1985-04-10

Family

ID=26335036

Family Applications (1)

Application Number Title Priority Date Filing Date
FI780059A FI67551C (fi) 1977-01-10 1978-01-09 Foerfarande foer framstaellning av alfa-(2r)-2-((1r 5s)-3-substituerad 7-oxo-4-oxa-2,6-diazabicyclo(3.2.0)hept-2-en-6-yl)-3-metyl- och halogen-substituerad metyl-3-butensyraestrar for anvaendning som mellanprodukter vid framstaellning av 7 ala-metoxi-1-oxa-detiacefalosporiner

Country Status (16)

Country Link
US (3) US4220766A (el)
AU (1) AU511062B2 (el)
CA (1) CA1090806A (el)
CH (1) CH638528A5 (el)
DE (1) DE2800860C2 (el)
DK (1) DK161330C (el)
FI (1) FI67551C (el)
FR (1) FR2376861A1 (el)
GB (1) GB1554821A (el)
IE (1) IE46134B1 (el)
IL (1) IL53770A (el)
NL (1) NL185668C (el)
NO (1) NO162561C (el)
NZ (1) NZ186153A (el)
PH (1) PH16072A (el)
SE (1) SE447114B (el)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU514377B2 (en) * 1977-02-15 1981-02-05 Shionogi & Co., Ltd. l-OXADETHIACEPHAM COMPOUNDS
CA1145339A (en) * 1979-04-30 1983-04-26 Eli Lilly And Company Allylic chlorination process and compounds prepared thereby
US4243588A (en) * 1979-06-19 1981-01-06 Eli Lilly And Company Process for novel oxazolinoazetidinones
US4357275A (en) * 1979-06-19 1982-11-02 Eli Lilly And Company Novel oxazolinoazetidinones and process therefor
US4482491A (en) * 1981-05-01 1984-11-13 Otsuka Kagaku Yakuhin Kabushiki Kaisha Thiazolinoazetidinone derivatives and process for the preparation of the same
EP0065488B1 (de) * 1981-05-19 1985-08-14 Ciba-Geigy Ag Verfahren zur Herstellung von 4-Thio-azetidinon-Verbindungen
JPS58185588A (ja) * 1982-04-23 1983-10-29 Shionogi & Co Ltd 空気酸化によるハロメチル化合物の酸化方法および酸化生成物
DE3231060A1 (de) * 1982-08-20 1984-02-23 Bayer Ag, 5090 Leverkusen In 6-stellung unsubstituierte 7-oxo-4-oxa-diazabicyclo-(3.2.0)-hept-2-en derivate, verfahren zu ihrer herstellung und ihre verwendung als zwischenprodukte zur synthese von ss-lactamantibiotika
US4532077A (en) * 1982-08-25 1985-07-30 Otsuka Kagaku Yakuhin Kabushiki Kaisha Thiazolineazetidinone-type compounds
US4525304A (en) * 1982-11-16 1985-06-25 Eli Lilly And Company Process for preparing oxazolinoazetidinones
JPS59164771A (ja) * 1983-03-10 1984-09-17 Otsuka Chem Co Ltd 塩素化アゼチジノン誘導体の製造方法
US4587053A (en) * 1984-04-26 1986-05-06 Eli Lilly And Company Preparation of oxazolines
CA2143519A1 (en) * 1994-03-11 1995-09-12 Markus Bohringer Beta-lactams
KR100518933B1 (ko) * 2002-04-09 2005-10-04 주식회사 엔지켐 옥사졸린-아제티디논 유도체의 정제방법
CN102286004A (zh) * 2011-09-21 2011-12-21 河北九派制药有限公司 拉氧头孢钠中间体的制备方法
CN102875571A (zh) * 2012-10-30 2013-01-16 陕西思尔生物科技有限公司 一种拉氧头孢钠中间体的合成方法
CN103254215B (zh) * 2013-05-24 2015-06-03 浙江东邦药业有限公司 一种烯丙基氯代氧头孢化合物的制备方法
CN104086563B (zh) * 2014-07-03 2016-09-07 江苏沙星化工有限公司 烯酸二苯甲酯的制备方法
CN111848646A (zh) * 2020-07-29 2020-10-30 绍兴众昌化工股份有限公司 甲基噻唑啉的制备方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3862164A (en) * 1971-02-03 1975-01-21 Lilly Co Eli Thiazolidine azetidinones
US3950352A (en) * 1972-04-10 1976-04-13 Queen's University 2,2-Dimethyl-3R-carboxy-6S-phenyl(or phenoxy)acetamido-1-oxa-4-aza-5R-bicyclo[3,2,0]heptan-7-one and processes for their production
GB1412996A (en) * 1973-01-03 1975-11-05 Squibb & Sons Inc Substituted 1-h-oxazolothiazinium halides
DE2356862A1 (de) * 1973-11-14 1975-05-15 Univ Kingston Sauerstoffanaloga von 6-aminopenicillansaeurederivaten und verfahren zu ihrer herstellung
GB1472863A (en) * 1974-08-15 1977-05-11 Farmaceutici Italia Intermediates for cephalosporin synthesis
US4155911A (en) * 1974-08-15 1979-05-22 Farmitalia Carlo Erba S.P.A. Process for the production of substituted 4-thia-2,6-diaza[3.2.0]-2-heptene-7-one
GB1468068A (en) * 1974-10-03 1977-03-23 Farmaceutici Italia Preparation of cephalosporin precursors
JPS607635B2 (ja) * 1976-04-27 1985-02-26 塩野義製薬株式会社 オキサゾリジン化合物
JPS53105491A (en) * 1977-02-25 1978-09-13 Shionogi & Co Ltd Oxazolinoazethidinylbutyrylic acid derivatives

Also Published As

Publication number Publication date
IE46134B1 (en) 1983-03-09
AU511062B2 (en) 1980-07-24
CH638528A5 (en) 1983-09-30
NL185668C (nl) 1990-06-18
NO162561C (no) 1990-01-17
US4220766A (en) 1980-09-02
AU3220078A (en) 1979-07-12
PH16072A (en) 1983-06-16
DE2800860C2 (de) 1996-11-28
NZ186153A (en) 1980-03-05
DK161330C (da) 1991-12-09
NL185668B (nl) 1990-01-16
NO780071L (no) 1978-07-11
GB1554821A (en) 1979-10-31
NO162561B (no) 1989-10-09
FI780059A (fi) 1978-07-11
DK588477A (da) 1978-07-11
SE7800192L (sv) 1978-07-11
US4271296A (en) 1981-06-02
FR2376861A1 (fr) 1978-08-04
FI67551B (fi) 1984-12-31
FR2376861B1 (el) 1982-04-02
SE447114B (sv) 1986-10-27
CA1090806A (en) 1980-12-02
IL53770A0 (en) 1978-04-30
NL7800262A (nl) 1978-07-12
IE780035L (en) 1978-07-10
DE2800860A1 (de) 1978-07-13
IL53770A (en) 1981-07-31
DK161330B (da) 1991-06-24
US4271295A (en) 1981-06-02

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