FI67081C - Analogifoerfarande foer framstaellning av ergolinderivat - Google Patents

Analogifoerfarande foer framstaellning av ergolinderivat Download PDF

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Publication number
FI67081C
FI67081C FI803736A FI803736A FI67081C FI 67081 C FI67081 C FI 67081C FI 803736 A FI803736 A FI 803736A FI 803736 A FI803736 A FI 803736A FI 67081 C FI67081 C FI 67081C
Authority
FI
Finland
Prior art keywords
group
methyl
ergoline
oxymethyl
eller
Prior art date
Application number
FI803736A
Other languages
English (en)
Finnish (fi)
Other versions
FI803736L (fi
FI67081B (fi
Inventor
Luigi Bernardi
Germano Bosisio
Sergio Mantegani
Alessandro Rossi
Aldemio Temperilli
Original Assignee
Erba Farmitalia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Farmitalia filed Critical Erba Farmitalia
Publication of FI803736L publication Critical patent/FI803736L/fi
Publication of FI67081B publication Critical patent/FI67081B/fi
Application granted granted Critical
Publication of FI67081C publication Critical patent/FI67081C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI803736A 1979-12-06 1980-12-02 Analogifoerfarande foer framstaellning av ergolinderivat FI67081C (fi)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
GB7942079 1979-12-06
GB7942079 1979-12-06
GB8007029 1980-03-01
GB8007029 1980-03-01
GB8017518 1980-05-29
GB8017518 1980-05-29

Publications (3)

Publication Number Publication Date
FI803736L FI803736L (fi) 1981-06-07
FI67081B FI67081B (fi) 1984-09-28
FI67081C true FI67081C (fi) 1985-01-10

Family

ID=27260819

Family Applications (1)

Application Number Title Priority Date Filing Date
FI803736A FI67081C (fi) 1979-12-06 1980-12-02 Analogifoerfarande foer framstaellning av ergolinderivat

Country Status (14)

Country Link
US (1) US4382940A (fr)
EP (1) EP0030351B1 (fr)
AU (1) AU537581B2 (fr)
CA (1) CA1153367A (fr)
DE (1) DE3068911D1 (fr)
DK (1) DK518580A (fr)
FI (1) FI67081C (fr)
FR (1) FR2471381A1 (fr)
HU (1) HU185020B (fr)
IE (1) IE51187B1 (fr)
IL (1) IL61614A (fr)
IT (1) IT1196411B (fr)
SU (1) SU1034606A3 (fr)
YU (1) YU309080A (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2120242A (en) * 1982-04-30 1983-11-30 Erba Farmitalia Ergoline derivatives
CH649998A5 (de) * 1982-08-09 1985-06-28 Sandoz Ag Ergolinderivate, ein verfahren zu ihrer herstellung und heilmittel, enthaltend diese ergolinderivate als wirkstoff.
EP0160842B1 (fr) * 1984-04-09 1994-06-22 Schering Aktiengesellschaft Dérivés d'ergoline substitués sur la position 2, procédés pour leur préparation et leur utilisation comme médicaments
DE3413660A1 (de) * 1984-04-09 1985-10-17 Schering AG, 1000 Berlin und 4709 Bergkamen Verfahren zur herstellung von 2-(trialkyl-silyl)-ergolinderivaten
GB8427536D0 (en) * 1984-10-31 1984-12-05 Lilly Industries Ltd Ergoline derivatives
US4675322A (en) * 1984-12-10 1987-06-23 Eli Lilly And Company 1-Substituted-6-n-propyl-8β-methylthio-methylergolines
US4683313A (en) * 1985-06-24 1987-07-28 Eli Lilly And Company 2-alkyl(or phenyl)thio-6-N alkyl ergolines and 4-dialkylaminotetrahydrobenz[c,d]indoles
US4801712A (en) * 1985-06-24 1989-01-31 Eli Lilly And Company 2-Alkyl(or phenyl)thio-6-n-alkylergolines are dopamine D-1 antagonists without D-2 agonist activity
DE3535930A1 (de) * 1985-10-04 1987-04-09 Schering Ag Neue 2-substituierte ergolinderivate
GB8615471D0 (en) * 1986-06-25 1986-07-30 Erba Farmitalia T-butyl ergoline derivatives
DE3938701A1 (de) * 1989-11-20 1991-05-23 Schering Ag Neue agroclavin- und elymoclavin-derivate, verfahren zu deren herstellung und deren verwendung in arzneimitteln
DE69330601T2 (de) * 1992-12-24 2002-07-04 Pharmacia & Upjohn Spa Serotoninergische ergolin derivate

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL128196C (fr) * 1961-05-29
US3228943A (en) * 1962-06-11 1966-01-11 Lumilysergol derivatives
GB1191099A (en) * 1968-03-07 1970-05-06 Farmaceutici Italia Ergoline Derivatives
IE41533B1 (en) * 1974-03-14 1980-01-30 Sandoz Ltd Thiomethyl ergolene derivatives
US3901894A (en) * 1974-06-06 1975-08-26 Lilly Co Eli 8-thiomethylergolines
US3968111A (en) * 1974-12-06 1976-07-06 Eli Lilly And Company 8,8-Disubstituted-6-methylergolines and related compounds
US3959288A (en) * 1974-12-13 1976-05-25 Eli Lilly And Company 8-Oxymethylergolines and process therefor
IT1192260B (it) * 1977-07-05 1988-03-31 Simes Derivati di ergoline-2-tioeteri e loro solfossidi
US4166182A (en) * 1978-02-08 1979-08-28 Eli Lilly And Company 6-n-propyl-8-methoxymethyl or methylmercaptomethylergolines and related compounds
IT1094965B (it) * 1978-04-05 1985-08-10 Corvi Mora E Procedimento di preparazione di derivati del lisergolo

Also Published As

Publication number Publication date
CA1153367A (fr) 1983-09-06
AU537581B2 (en) 1984-07-05
EP0030351A2 (fr) 1981-06-17
IT1196411B (it) 1988-11-16
EP0030351B1 (fr) 1984-08-08
IT8026488A0 (it) 1980-12-05
IL61614A (en) 1984-04-30
AU6495880A (en) 1981-06-11
YU309080A (en) 1983-02-28
IE51187B1 (en) 1986-10-29
FR2471381A1 (fr) 1981-06-19
IL61614A0 (en) 1981-01-30
FI803736L (fi) 1981-06-07
FR2471381B1 (fr) 1983-01-07
DK518580A (da) 1981-06-07
SU1034606A3 (ru) 1983-08-07
HU185020B (en) 1984-11-28
EP0030351A3 (en) 1981-12-02
US4382940A (en) 1983-05-10
FI67081B (fi) 1984-09-28
IE802558L (en) 1981-06-06
DE3068911D1 (en) 1984-09-13

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Owner name: FARMITALIA CARLO ERBA S.P.A.