IT8026488A0 - Derivati ergolinici, loro preparazione e composizioni terapeutiche che li contengono. - Google Patents
Derivati ergolinici, loro preparazione e composizioni terapeutiche che li contengono.Info
- Publication number
- IT8026488A0 IT8026488A0 IT8026488A IT2648880A IT8026488A0 IT 8026488 A0 IT8026488 A0 IT 8026488A0 IT 8026488 A IT8026488 A IT 8026488A IT 2648880 A IT2648880 A IT 2648880A IT 8026488 A0 IT8026488 A0 IT 8026488A0
- Authority
- IT
- Italy
- Prior art keywords
- contain
- preparation
- therapeutic compositions
- ergoline derivatives
- ergoline
- Prior art date
Links
- AWFDCTXCTHGORH-HGHGUNKESA-N 6-[4-[(6ar,9r,10ar)-5-bromo-7-methyl-6,6a,8,9,10,10a-hexahydro-4h-indolo[4,3-fg]quinoline-9-carbonyl]piperazin-1-yl]-1-methylpyridin-2-one Chemical class O=C([C@H]1CN([C@H]2[C@@H](C=3C=CC=C4NC(Br)=C(C=34)C2)C1)C)N(CC1)CCN1C1=CC=CC(=O)N1C AWFDCTXCTHGORH-HGHGUNKESA-N 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pain & Pain Management (AREA)
- Anesthesiology (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB7942079 | 1979-12-06 | ||
| GB8007029 | 1980-03-01 | ||
| GB8017518 | 1980-05-29 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IT8026488A0 true IT8026488A0 (it) | 1980-12-05 |
| IT1196411B IT1196411B (it) | 1988-11-16 |
Family
ID=27260819
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT26488/80A IT1196411B (it) | 1979-12-06 | 1980-12-05 | Derivati ergolinici,loro preparazione e composizioni terapeutiche che li contengono |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US4382940A (it) |
| EP (1) | EP0030351B1 (it) |
| AU (1) | AU537581B2 (it) |
| CA (1) | CA1153367A (it) |
| DE (1) | DE3068911D1 (it) |
| DK (1) | DK518580A (it) |
| FI (1) | FI67081C (it) |
| FR (1) | FR2471381A1 (it) |
| HU (1) | HU185020B (it) |
| IE (1) | IE51187B1 (it) |
| IL (1) | IL61614A (it) |
| IT (1) | IT1196411B (it) |
| SU (1) | SU1034606A3 (it) |
| YU (1) | YU309080A (it) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2120242A (en) * | 1982-04-30 | 1983-11-30 | Erba Farmitalia | Ergoline derivatives |
| CH649998A5 (de) * | 1982-08-09 | 1985-06-28 | Sandoz Ag | Ergolinderivate, ein verfahren zu ihrer herstellung und heilmittel, enthaltend diese ergolinderivate als wirkstoff. |
| DE3413660A1 (de) * | 1984-04-09 | 1985-10-17 | Schering AG, 1000 Berlin und 4709 Bergkamen | Verfahren zur herstellung von 2-(trialkyl-silyl)-ergolinderivaten |
| DE3587860D1 (de) * | 1984-04-09 | 1994-07-28 | Schering Ag | 2-substituierte Ergolin-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel. |
| GB8427536D0 (en) * | 1984-10-31 | 1984-12-05 | Lilly Industries Ltd | Ergoline derivatives |
| US4675322A (en) * | 1984-12-10 | 1987-06-23 | Eli Lilly And Company | 1-Substituted-6-n-propyl-8β-methylthio-methylergolines |
| US4801712A (en) * | 1985-06-24 | 1989-01-31 | Eli Lilly And Company | 2-Alkyl(or phenyl)thio-6-n-alkylergolines are dopamine D-1 antagonists without D-2 agonist activity |
| US4683313A (en) * | 1985-06-24 | 1987-07-28 | Eli Lilly And Company | 2-alkyl(or phenyl)thio-6-N alkyl ergolines and 4-dialkylaminotetrahydrobenz[c,d]indoles |
| DE3535930A1 (de) * | 1985-10-04 | 1987-04-09 | Schering Ag | Neue 2-substituierte ergolinderivate |
| GB8615471D0 (en) * | 1986-06-25 | 1986-07-30 | Erba Farmitalia | T-butyl ergoline derivatives |
| DE3938701A1 (de) * | 1989-11-20 | 1991-05-23 | Schering Ag | Neue agroclavin- und elymoclavin-derivate, verfahren zu deren herstellung und deren verwendung in arzneimitteln |
| AU669597B2 (en) * | 1992-12-24 | 1996-06-13 | Pharmacia & Upjohn S.P.A. | Serotoninergic ergoline derivatives |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL278401A (it) * | 1961-05-29 | |||
| US3228943A (en) * | 1962-06-11 | 1966-01-11 | Lumilysergol derivatives | |
| DE1910930A1 (de) * | 1968-03-07 | 1969-10-16 | Farmaceutici Italia | Verfahren zur Herstellung von neuen 1,6-Dimethyl-10alpha-ergolinderivaten |
| IE41533B1 (en) * | 1974-03-14 | 1980-01-30 | Sandoz Ltd | Thiomethyl ergolene derivatives |
| US3901894A (en) * | 1974-06-06 | 1975-08-26 | Lilly Co Eli | 8-thiomethylergolines |
| US3968111A (en) * | 1974-12-06 | 1976-07-06 | Eli Lilly And Company | 8,8-Disubstituted-6-methylergolines and related compounds |
| US3959288A (en) * | 1974-12-13 | 1976-05-25 | Eli Lilly And Company | 8-Oxymethylergolines and process therefor |
| IT1192260B (it) * | 1977-07-05 | 1988-03-31 | Simes | Derivati di ergoline-2-tioeteri e loro solfossidi |
| US4166182A (en) * | 1978-02-08 | 1979-08-28 | Eli Lilly And Company | 6-n-propyl-8-methoxymethyl or methylmercaptomethylergolines and related compounds |
| IT1094965B (it) * | 1978-04-05 | 1985-08-10 | Corvi Mora E | Procedimento di preparazione di derivati del lisergolo |
-
1980
- 1980-12-01 US US06/211,920 patent/US4382940A/en not_active Expired - Lifetime
- 1980-12-02 FR FR8025571A patent/FR2471381A1/fr active Granted
- 1980-12-02 FI FI803736A patent/FI67081C/fi not_active IP Right Cessation
- 1980-12-02 AU AU64958/80A patent/AU537581B2/en not_active Ceased
- 1980-12-02 EP EP80107522A patent/EP0030351B1/en not_active Expired
- 1980-12-02 DE DE8080107522T patent/DE3068911D1/de not_active Expired
- 1980-12-02 IL IL61614A patent/IL61614A/xx unknown
- 1980-12-02 CA CA000365922A patent/CA1153367A/en not_active Expired
- 1980-12-04 DK DK518580A patent/DK518580A/da not_active Application Discontinuation
- 1980-12-05 SU SU803212054A patent/SU1034606A3/ru active
- 1980-12-05 HU HU802916A patent/HU185020B/hu unknown
- 1980-12-05 IT IT26488/80A patent/IT1196411B/it active
- 1980-12-05 YU YU03090/80A patent/YU309080A/xx unknown
- 1980-12-05 IE IE2558/80A patent/IE51187B1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL61614A0 (en) | 1981-01-30 |
| EP0030351A2 (en) | 1981-06-17 |
| HU185020B (en) | 1984-11-28 |
| FI803736L (fi) | 1981-06-07 |
| CA1153367A (en) | 1983-09-06 |
| YU309080A (en) | 1983-02-28 |
| IT1196411B (it) | 1988-11-16 |
| DE3068911D1 (en) | 1984-09-13 |
| FI67081C (fi) | 1985-01-10 |
| EP0030351A3 (en) | 1981-12-02 |
| IE51187B1 (en) | 1986-10-29 |
| EP0030351B1 (en) | 1984-08-08 |
| FR2471381A1 (fr) | 1981-06-19 |
| SU1034606A3 (ru) | 1983-08-07 |
| IL61614A (en) | 1984-04-30 |
| AU537581B2 (en) | 1984-07-05 |
| IE802558L (en) | 1981-06-06 |
| FR2471381B1 (it) | 1983-01-07 |
| FI67081B (fi) | 1984-09-28 |
| DK518580A (da) | 1981-06-07 |
| AU6495880A (en) | 1981-06-11 |
| US4382940A (en) | 1983-05-10 |
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