DE3068911D1 - Ergoline derivatives, their preparation and therapeutic composition containing them - Google Patents

Ergoline derivatives, their preparation and therapeutic composition containing them

Info

Publication number
DE3068911D1
DE3068911D1 DE8080107522T DE3068911T DE3068911D1 DE 3068911 D1 DE3068911 D1 DE 3068911D1 DE 8080107522 T DE8080107522 T DE 8080107522T DE 3068911 T DE3068911 T DE 3068911T DE 3068911 D1 DE3068911 D1 DE 3068911D1
Authority
DE
Germany
Prior art keywords
preparation
composition containing
therapeutic composition
ergoline derivatives
ergoline
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8080107522T
Other languages
English (en)
Inventor
Luigi Bernardi
Germano Bosisio
Sergio Mantegani
Alessandro Dr Rossi
Aldemio Temperilli
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Farmitalia Carlo Erba SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmitalia Carlo Erba SRL filed Critical Farmitalia Carlo Erba SRL
Application granted granted Critical
Publication of DE3068911D1 publication Critical patent/DE3068911D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE8080107522T 1979-12-06 1980-12-02 Ergoline derivatives, their preparation and therapeutic composition containing them Expired DE3068911D1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB7942079 1979-12-06
GB8007029 1980-03-01
GB8017518 1980-05-29

Publications (1)

Publication Number Publication Date
DE3068911D1 true DE3068911D1 (en) 1984-09-13

Family

ID=27260819

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8080107522T Expired DE3068911D1 (en) 1979-12-06 1980-12-02 Ergoline derivatives, their preparation and therapeutic composition containing them

Country Status (14)

Country Link
US (1) US4382940A (de)
EP (1) EP0030351B1 (de)
AU (1) AU537581B2 (de)
CA (1) CA1153367A (de)
DE (1) DE3068911D1 (de)
DK (1) DK518580A (de)
FI (1) FI67081C (de)
FR (1) FR2471381A1 (de)
HU (1) HU185020B (de)
IE (1) IE51187B1 (de)
IL (1) IL61614A (de)
IT (1) IT1196411B (de)
SU (1) SU1034606A3 (de)
YU (1) YU309080A (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2120242A (en) * 1982-04-30 1983-11-30 Erba Farmitalia Ergoline derivatives
CH649998A5 (de) * 1982-08-09 1985-06-28 Sandoz Ag Ergolinderivate, ein verfahren zu ihrer herstellung und heilmittel, enthaltend diese ergolinderivate als wirkstoff.
EP0160842B1 (de) * 1984-04-09 1994-06-22 Schering Aktiengesellschaft 2-substituierte Ergolin-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
DE3413660A1 (de) * 1984-04-09 1985-10-17 Schering AG, 1000 Berlin und 4709 Bergkamen Verfahren zur herstellung von 2-(trialkyl-silyl)-ergolinderivaten
GB8427536D0 (en) * 1984-10-31 1984-12-05 Lilly Industries Ltd Ergoline derivatives
US4675322A (en) * 1984-12-10 1987-06-23 Eli Lilly And Company 1-Substituted-6-n-propyl-8β-methylthio-methylergolines
US4683313A (en) * 1985-06-24 1987-07-28 Eli Lilly And Company 2-alkyl(or phenyl)thio-6-N alkyl ergolines and 4-dialkylaminotetrahydrobenz[c,d]indoles
US4801712A (en) * 1985-06-24 1989-01-31 Eli Lilly And Company 2-Alkyl(or phenyl)thio-6-n-alkylergolines are dopamine D-1 antagonists without D-2 agonist activity
DE3535930A1 (de) * 1985-10-04 1987-04-09 Schering Ag Neue 2-substituierte ergolinderivate
GB8615471D0 (en) * 1986-06-25 1986-07-30 Erba Farmitalia T-butyl ergoline derivatives
DE3938701A1 (de) * 1989-11-20 1991-05-23 Schering Ag Neue agroclavin- und elymoclavin-derivate, verfahren zu deren herstellung und deren verwendung in arzneimitteln
DE69330601T2 (de) * 1992-12-24 2002-07-04 Pharmacia & Upjohn Spa Serotoninergische ergolin derivate

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL128196C (de) * 1961-05-29
US3228943A (en) * 1962-06-11 1966-01-11 Lumilysergol derivatives
GB1191099A (en) * 1968-03-07 1970-05-06 Farmaceutici Italia Ergoline Derivatives
IE41533B1 (en) * 1974-03-14 1980-01-30 Sandoz Ltd Thiomethyl ergolene derivatives
US3901894A (en) * 1974-06-06 1975-08-26 Lilly Co Eli 8-thiomethylergolines
US3968111A (en) * 1974-12-06 1976-07-06 Eli Lilly And Company 8,8-Disubstituted-6-methylergolines and related compounds
US3959288A (en) * 1974-12-13 1976-05-25 Eli Lilly And Company 8-Oxymethylergolines and process therefor
IT1192260B (it) * 1977-07-05 1988-03-31 Simes Derivati di ergoline-2-tioeteri e loro solfossidi
US4166182A (en) * 1978-02-08 1979-08-28 Eli Lilly And Company 6-n-propyl-8-methoxymethyl or methylmercaptomethylergolines and related compounds
IT1094965B (it) * 1978-04-05 1985-08-10 Corvi Mora E Procedimento di preparazione di derivati del lisergolo

Also Published As

Publication number Publication date
CA1153367A (en) 1983-09-06
AU537581B2 (en) 1984-07-05
EP0030351A2 (de) 1981-06-17
IT1196411B (it) 1988-11-16
EP0030351B1 (de) 1984-08-08
IT8026488A0 (it) 1980-12-05
IL61614A (en) 1984-04-30
AU6495880A (en) 1981-06-11
YU309080A (en) 1983-02-28
IE51187B1 (en) 1986-10-29
FR2471381A1 (fr) 1981-06-19
IL61614A0 (en) 1981-01-30
FI803736L (fi) 1981-06-07
FR2471381B1 (de) 1983-01-07
DK518580A (da) 1981-06-07
SU1034606A3 (ru) 1983-08-07
HU185020B (en) 1984-11-28
EP0030351A3 (en) 1981-12-02
US4382940A (en) 1983-05-10
FI67081B (fi) 1984-09-28
IE802558L (en) 1981-06-06
FI67081C (fi) 1985-01-10

Similar Documents

Publication Publication Date Title
DE2861316D1 (en) Thienothiazine derivatives, their preparation and compositions containing them
DE2963320D1 (en) Ergoline compounds, their preparation and pharmaceutical compositions containing them
IL55183A0 (en) Novel imidazoquinazoline derivatives, their preparation and pharmaceutical compositions containing them
IL60129A0 (en) Phenylsulphonamide derivatives,their preparation and pharmaceutical compositions containing them
PH15719A (en) Aminoalkylbenzoic derivatives,pharmaceutical composition and method of use
IL49405A0 (en) Thieno-pyridine derivatives,their preparation and therapeutic compositions containing them
DE3068678D1 (en) 3-aminopropoxyaryl derivatives, their preparation and pharmaceutical compositions containing them
DE3069771D1 (en) Novel ergoline derivatives, compositions containing them, their preparation and use as pharmaceuticals
IL61481A0 (en) Piperidylbenzimidazolinone derivatives,their preparation and pharmaceutical compositions containing them
IL60617A0 (en) Triazolopyridazine derivative,their preparation and pharmaceutical compositions containing them
DE3068911D1 (en) Ergoline derivatives, their preparation and therapeutic composition containing them
GB2051062B (en) 3-vinyl-cephalosporin derivatives and their preparation
IL60094A0 (en) Tetracyclic compounds,their preparation and pharmaceutical compositions containing them
IL60359A (en) Dialkylaminoalkoxyiminocycloalkane derivatives,their preparation and pharmaceutical compositions containing them
IL60058A0 (en) Hydroxyamino-eburnane derivatives,their preparation and pharmaceutical compositions containing them
IL60927A (en) Amino-propanoloxytetrahydroquinoline derivatives,their preparation and pharmaceutical compositions containing them
IL62519A0 (en) Ergoline derivatives,their preparation and pharmaceutical compositions containing them
IL60548A0 (en) Ergol-8-ene and ergolin derivatives,their preparation and pharmaceutical compositions containing them
JPS5639067A (en) Pyrrolidineedione derivatives and mildewcidal composition containing them
IL61250A (en) Pyridine derivatives,their preparation and pharmaceutical compositions containing them
IL59252A (en) 4-amino-2-piperidinoquinazoline derivatives,their preparation and pharmaceutical compositions containing them
IL59396A0 (en) Penicillin derivatives,their preparation and pharmaceutical compositions containing them
KE3622A (en) Ergot peptide derivatives,their preparation and pharmaceutical compositions containing them
JPS5610184A (en) Pyridine derivatives and medicinal composition containing them
CY1334A (en) 17-cycloalkylmethyl-6-methylene-morphinane derivatives and their preparation

Legal Events

Date Code Title Description
8339 Ceased/non-payment of the annual fee