DE3068911D1 - Ergoline derivatives, their preparation and therapeutic composition containing them - Google Patents

Ergoline derivatives, their preparation and therapeutic composition containing them

Info

Publication number
DE3068911D1
DE3068911D1 DE8080107522T DE3068911T DE3068911D1 DE 3068911 D1 DE3068911 D1 DE 3068911D1 DE 8080107522 T DE8080107522 T DE 8080107522T DE 3068911 T DE3068911 T DE 3068911T DE 3068911 D1 DE3068911 D1 DE 3068911D1
Authority
DE
Germany
Prior art keywords
preparation
composition containing
therapeutic composition
ergoline derivatives
ergoline
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8080107522T
Other languages
English (en)
Inventor
Luigi Bernardi
Germano Bosisio
Sergio Mantegani
Alessandro Dr Rossi
Aldemio Temperilli
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Farmitalia Carlo Erba SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmitalia Carlo Erba SRL filed Critical Farmitalia Carlo Erba SRL
Application granted granted Critical
Publication of DE3068911D1 publication Critical patent/DE3068911D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE8080107522T 1979-12-06 1980-12-02 Ergoline derivatives, their preparation and therapeutic composition containing them Expired DE3068911D1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB7942079 1979-12-06
GB8007029 1980-03-01
GB8017518 1980-05-29

Publications (1)

Publication Number Publication Date
DE3068911D1 true DE3068911D1 (en) 1984-09-13

Family

ID=27260819

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8080107522T Expired DE3068911D1 (en) 1979-12-06 1980-12-02 Ergoline derivatives, their preparation and therapeutic composition containing them

Country Status (14)

Country Link
US (1) US4382940A (de)
EP (1) EP0030351B1 (de)
AU (1) AU537581B2 (de)
CA (1) CA1153367A (de)
DE (1) DE3068911D1 (de)
DK (1) DK518580A (de)
FI (1) FI67081C (de)
FR (1) FR2471381A1 (de)
HU (1) HU185020B (de)
IE (1) IE51187B1 (de)
IL (1) IL61614A (de)
IT (1) IT1196411B (de)
SU (1) SU1034606A3 (de)
YU (1) YU309080A (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2120242A (en) * 1982-04-30 1983-11-30 Erba Farmitalia Ergoline derivatives
CH649998A5 (de) * 1982-08-09 1985-06-28 Sandoz Ag Ergolinderivate, ein verfahren zu ihrer herstellung und heilmittel, enthaltend diese ergolinderivate als wirkstoff.
DE3413660A1 (de) * 1984-04-09 1985-10-17 Schering AG, 1000 Berlin und 4709 Bergkamen Verfahren zur herstellung von 2-(trialkyl-silyl)-ergolinderivaten
DE3587860D1 (de) * 1984-04-09 1994-07-28 Schering Ag 2-substituierte Ergolin-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel.
GB8427536D0 (en) * 1984-10-31 1984-12-05 Lilly Industries Ltd Ergoline derivatives
US4675322A (en) * 1984-12-10 1987-06-23 Eli Lilly And Company 1-Substituted-6-n-propyl-8β-methylthio-methylergolines
US4683313A (en) * 1985-06-24 1987-07-28 Eli Lilly And Company 2-alkyl(or phenyl)thio-6-N alkyl ergolines and 4-dialkylaminotetrahydrobenz[c,d]indoles
US4801712A (en) * 1985-06-24 1989-01-31 Eli Lilly And Company 2-Alkyl(or phenyl)thio-6-n-alkylergolines are dopamine D-1 antagonists without D-2 agonist activity
DE3535930A1 (de) * 1985-10-04 1987-04-09 Schering Ag Neue 2-substituierte ergolinderivate
GB8615471D0 (en) * 1986-06-25 1986-07-30 Erba Farmitalia T-butyl ergoline derivatives
DE3938701A1 (de) * 1989-11-20 1991-05-23 Schering Ag Neue agroclavin- und elymoclavin-derivate, verfahren zu deren herstellung und deren verwendung in arzneimitteln
PT628042E (pt) * 1992-12-24 2002-01-30 Pharmacia & Upjohn Spa Derivados de ergolina serotoninergicos

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL278401A (de) * 1961-05-29
US3228943A (en) * 1962-06-11 1966-01-11 Lumilysergol derivatives
DE1910930A1 (de) * 1968-03-07 1969-10-16 Farmaceutici Italia Verfahren zur Herstellung von neuen 1,6-Dimethyl-10alpha-ergolinderivaten
IE41533B1 (en) * 1974-03-14 1980-01-30 Sandoz Ltd Thiomethyl ergolene derivatives
US3901894A (en) * 1974-06-06 1975-08-26 Lilly Co Eli 8-thiomethylergolines
US3968111A (en) * 1974-12-06 1976-07-06 Eli Lilly And Company 8,8-Disubstituted-6-methylergolines and related compounds
US3959288A (en) * 1974-12-13 1976-05-25 Eli Lilly And Company 8-Oxymethylergolines and process therefor
IT1192260B (it) * 1977-07-05 1988-03-31 Simes Derivati di ergoline-2-tioeteri e loro solfossidi
US4166182A (en) * 1978-02-08 1979-08-28 Eli Lilly And Company 6-n-propyl-8-methoxymethyl or methylmercaptomethylergolines and related compounds
IT1094965B (it) * 1978-04-05 1985-08-10 Corvi Mora E Procedimento di preparazione di derivati del lisergolo

Also Published As

Publication number Publication date
FI67081C (fi) 1985-01-10
IL61614A0 (en) 1981-01-30
SU1034606A3 (ru) 1983-08-07
IT1196411B (it) 1988-11-16
IT8026488A0 (it) 1980-12-05
FR2471381B1 (de) 1983-01-07
FI803736L (fi) 1981-06-07
IE802558L (en) 1981-06-06
EP0030351A2 (de) 1981-06-17
AU6495880A (en) 1981-06-11
AU537581B2 (en) 1984-07-05
FI67081B (fi) 1984-09-28
YU309080A (en) 1983-02-28
IL61614A (en) 1984-04-30
FR2471381A1 (fr) 1981-06-19
EP0030351B1 (de) 1984-08-08
EP0030351A3 (en) 1981-12-02
HU185020B (en) 1984-11-28
CA1153367A (en) 1983-09-06
DK518580A (da) 1981-06-07
IE51187B1 (en) 1986-10-29
US4382940A (en) 1983-05-10

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Legal Events

Date Code Title Description
8339 Ceased/non-payment of the annual fee