FI66177C - Foerfarande foer framstaellning av terapeutiskt anvaendbara ,5-diaryl-2-(substituerad-tio)imidazoler - Google Patents

Foerfarande foer framstaellning av terapeutiskt anvaendbara ,5-diaryl-2-(substituerad-tio)imidazoler Download PDF

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Publication number
FI66177C
FI66177C FI762290A FI762290A FI66177C FI 66177 C FI66177 C FI 66177C FI 762290 A FI762290 A FI 762290A FI 762290 A FI762290 A FI 762290A FI 66177 C FI66177 C FI 66177C
Authority
FI
Finland
Prior art keywords
imidazole
alkyl
mixture
bis
methoxyphenyl
Prior art date
Application number
FI762290A
Other languages
English (en)
Finnish (fi)
Other versions
FI762290A (es
FI66177B (fi
Inventor
Saul Carl Cherkofsky
Thomas Ray Sharpe
Original Assignee
Du Pont
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont filed Critical Du Pont
Publication of FI762290A publication Critical patent/FI762290A/fi
Publication of FI66177B publication Critical patent/FI66177B/fi
Application granted granted Critical
Publication of FI66177C publication Critical patent/FI66177C/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/84—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
FI762290A 1975-08-11 1976-08-10 Foerfarande foer framstaellning av terapeutiskt anvaendbara ,5-diaryl-2-(substituerad-tio)imidazoler FI66177C (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US60365075A 1975-08-11 1975-08-11
US60365075 1975-08-11
US69128276A 1976-06-09 1976-06-09
US69128276 1976-06-09

Publications (3)

Publication Number Publication Date
FI762290A FI762290A (es) 1977-02-12
FI66177B FI66177B (fi) 1984-05-31
FI66177C true FI66177C (fi) 1984-09-10

Family

ID=27084480

Family Applications (1)

Application Number Title Priority Date Filing Date
FI762290A FI66177C (fi) 1975-08-11 1976-08-10 Foerfarande foer framstaellning av terapeutiskt anvaendbara ,5-diaryl-2-(substituerad-tio)imidazoler

Country Status (26)

Country Link
JP (1) JPS6011702B2 (es)
AR (2) AR215591A1 (es)
AU (1) AU508605B2 (es)
CA (1) CA1074327A (es)
CH (1) CH638791A5 (es)
DD (1) DD126244A5 (es)
DE (1) DE2635876A1 (es)
DK (1) DK361376A (es)
ES (2) ES450601A1 (es)
FI (1) FI66177C (es)
FR (1) FR2320745A1 (es)
GB (1) GB1516908A (es)
GR (1) GR61145B (es)
HU (1) HU174707B (es)
IE (1) IE44019B1 (es)
IL (1) IL50230A (es)
LU (1) LU75578A1 (es)
MX (1) MX3932E (es)
NL (1) NL7608915A (es)
NO (1) NO146571C (es)
NZ (1) NZ181731A (es)
PH (1) PH11857A (es)
PT (1) PT65464B (es)
SE (1) SE428686B (es)
SU (1) SU640662A3 (es)
YU (1) YU198176A (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK16778A (da) * 1977-02-09 1978-08-10 Du Pont Imidazolderivater deres anvendelser og fremstilling
LU77703A1 (de) * 1977-07-07 1979-03-26 Ciba Geigy Ag Verfahren zur herstellung von bicyclischen thia-diaza-verbindungen
DE2963572D1 (en) * 1978-04-11 1982-10-21 Ciba Geigy Ag Mercapto-imidazole derivatives, their preparation, mercapto-imidazole derivatives for the treatment of inflammatory diseases and their pharmaceutical compositions
DE2823197A1 (de) * 1978-05-24 1979-11-29 Schering Ag Neue imidazolderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
US4308277A (en) * 1978-08-10 1981-12-29 Ciba-Geigy Corporation 2,4,5-Trisubstituted imidazolines and pharmaceutical compositions containing same
US4188397A (en) * 1978-09-22 1980-02-12 Smithkline Corporation 2,2-Alkyldiylbis(thio)bis(imidazoles)
US4215135A (en) * 1979-06-08 1980-07-29 E. I. Du Pont De Nemours And Company Antiinflammatory 2-substituted-1H-phenanthro[9,10-d]imidazoles
DE2856909A1 (de) * 1978-12-28 1980-07-17 Schering Ag Neue imidazolderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
GB8907656D0 (en) * 1989-04-05 1989-05-17 May & Baker Ltd New compositions of matter
CA2295021A1 (en) * 1997-06-30 1999-01-28 Ortho-Mcneil Pharmaceutical, Inc. 2-substituted imidazoles useful in the treatment of inflammatory diseases
DE10222103A1 (de) * 2002-05-17 2003-11-27 Merckle Gmbh Chem Pharm Fabrik 2-Thio-substituierte Imidazolderivate und ihre Verwendung in der Pharmazie

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1509975A (fr) * 1965-10-21 1968-01-19 Geigy Ag J R Dérivés de l'imidazole et leur préparation
US3651080A (en) * 1969-11-07 1972-03-21 Ciba Geigy Corp Certain substituted 2-alkylmercaptoimidazole derivatives
US3636003A (en) * 1969-11-17 1972-01-18 Geigy Chem Corp Substituted 2-mercaptoimidazole derivatives
US3714179A (en) * 1970-09-08 1973-01-30 Searle & Co 1-alkyl-2-furfurylthioimidazoles and congeners
US3707475A (en) * 1970-11-16 1972-12-26 Pfizer Antiinflammatory imidazoles

Also Published As

Publication number Publication date
AR215591A1 (es) 1979-10-31
CA1074327A (en) 1980-03-25
FI762290A (es) 1977-02-12
IL50230A (en) 1979-07-25
PT65464A (en) 1976-09-01
NZ181731A (en) 1978-11-13
GB1516908A (en) 1978-07-05
NO146571B (no) 1982-07-19
PH11857A (en) 1978-08-03
MX3932E (es) 1981-10-02
FR2320745B1 (es) 1978-12-22
IE44019L (en) 1977-02-11
AU1671176A (en) 1978-02-16
SU640662A3 (ru) 1978-12-30
PT65464B (en) 1978-08-02
FR2320745A1 (fr) 1977-03-11
NO762754L (es) 1977-02-14
AR218054A1 (es) 1980-05-15
ES461193A1 (es) 1978-12-01
IL50230A0 (en) 1976-10-31
SE7607615L (sv) 1977-02-12
DD126244A5 (es) 1977-07-06
FI66177B (fi) 1984-05-31
YU198176A (en) 1982-10-31
SE428686B (sv) 1983-07-18
HU174707B (hu) 1980-03-28
LU75578A1 (es) 1978-04-13
CH638791A5 (de) 1983-10-14
NO146571C (no) 1982-10-27
DE2635876A1 (de) 1977-03-03
AU508605B2 (en) 1980-03-27
IE44019B1 (en) 1981-07-29
JPS5223076A (en) 1977-02-21
GR61145B (en) 1978-09-27
ES450601A1 (es) 1978-01-16
DK361376A (da) 1977-02-12
JPS6011702B2 (ja) 1985-03-27
NL7608915A (nl) 1977-02-15

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Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: E.I. DU PONT DE NEMOURS AND COMPANY