FI65068C - Foerfarande foer framstaellning av farmakologiskt vaerdefulla 7-fenyl-2,3-dihydro-imidazo(1,2-a)imidazoler och deras syraadditionssalter - Google Patents

Foerfarande foer framstaellning av farmakologiskt vaerdefulla 7-fenyl-2,3-dihydro-imidazo(1,2-a)imidazoler och deras syraadditionssalter Download PDF

Info

Publication number
FI65068C
FI65068C FI791996A FI791996A FI65068C FI 65068 C FI65068 C FI 65068C FI 791996 A FI791996 A FI 791996A FI 791996 A FI791996 A FI 791996A FI 65068 C FI65068 C FI 65068C
Authority
FI
Finland
Prior art keywords
phenyl
formula
imidazo
compounds
substituted
Prior art date
Application number
FI791996A
Other languages
English (en)
Finnish (fi)
Other versions
FI791996A (fi
FI65068B (fi
Inventor
Helmut Staehle
Herbert Koeppe
Werner Kummer
Walter Kobinger
Christian Lillie
Ludwig Pichler
Original Assignee
Boehringer Sohn Ingelheim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim
Publication of FI791996A publication Critical patent/FI791996A/fi
Application granted granted Critical
Publication of FI65068B publication Critical patent/FI65068B/fi
Publication of FI65068C publication Critical patent/FI65068C/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Epoxy Resins (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
FI791996A 1978-06-23 1979-06-21 Foerfarande foer framstaellning av farmakologiskt vaerdefulla 7-fenyl-2,3-dihydro-imidazo(1,2-a)imidazoler och deras syraadditionssalter FI65068C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19782827617 DE2827617A1 (de) 1978-06-23 1978-06-23 Neue imidazo eckige klammer auf 1,2- alpha eckige klammer zu imidazole, deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zu deren herstellung
DE2827617 1978-06-23

Publications (3)

Publication Number Publication Date
FI791996A FI791996A (fi) 1979-12-24
FI65068B FI65068B (fi) 1983-11-30
FI65068C true FI65068C (fi) 1984-03-12

Family

ID=6042588

Family Applications (1)

Application Number Title Priority Date Filing Date
FI791996A FI65068C (fi) 1978-06-23 1979-06-21 Foerfarande foer framstaellning av farmakologiskt vaerdefulla 7-fenyl-2,3-dihydro-imidazo(1,2-a)imidazoler och deras syraadditionssalter

Country Status (18)

Country Link
US (1) US4210659A (fr)
EP (1) EP0006451B1 (fr)
JP (1) JPS554392A (fr)
AT (1) ATE853T1 (fr)
AU (1) AU519287B2 (fr)
CA (1) CA1115280A (fr)
DE (2) DE2827617A1 (fr)
DK (1) DK146389C (fr)
ES (4) ES481799A1 (fr)
FI (1) FI65068C (fr)
IE (1) IE48355B1 (fr)
IL (1) IL57627A (fr)
MX (1) MX5687E (fr)
NO (1) NO151465C (fr)
NZ (1) NZ190801A (fr)
PT (1) PT69804A (fr)
YU (1) YU42307B (fr)
ZA (1) ZA793108B (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3042636A1 (de) * 1980-11-12 1982-06-16 C.H. Boehringer Sohn, 6507 Ingelheim Neue 7-(2,6-dibrom-4-methylphenyl)-2,3-dihydro-imidazo(1,2-a)imidazole, deren saeureadditionssalze, diese enhthaltende arzneimittel und verfahren zu deren herstellung
DE3124701A1 (de) * 1981-06-24 1983-01-13 Boehringer Ingelheim KG, 6507 Ingelheim Neue l-substituierte imidazo (1,2-a)imidazole, deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zu deren herstellung
EP1309595A2 (fr) * 2000-08-09 2003-05-14 Boehringer Ingelheim Pharmaceuticals Inc. Synthese de (r)-3-(4-bromobenzyl)-1-(3,5-dichlorophenyl)-5-iodo-3-methyl-1-h-imidazo 1,2-a]imidazol-2-one
SK9222003A3 (en) * 2001-01-26 2004-05-04 Bristol Myers Squibb Co Imidazolyl derivatives as corticotropin releasing factor inhibitors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2393826A (en) * 1944-02-28 1946-01-29 Commercial Solvents Corp 1,3,7-triazabicyclo [3.3.0] octanes
DE2109524A1 (en) * 1971-03-01 1972-09-07 CH. Boehringer Sohn, 6507 Ingelheim 2,3-dihydr-dioxo-imidazo (1,2-a) imidazoles or pyrimidines - with hypotensive and neuroleptic activity
DE2118261A1 (de) * 1971-04-15 1972-11-02 C.H. Boehringer Sohn, 6507 Ingelheim Neue N-haltige Bicyclen, deren Säureadditionssalze sowie Verfahren zu deren Herstellung
US3865836A (en) * 1972-12-08 1975-02-11 Janssen Pharmaceutica Nv Bicyclic imidazoles

Also Published As

Publication number Publication date
DE2827617A1 (de) 1980-01-10
NO151465C (no) 1985-04-17
NO151465B (no) 1985-01-02
IE791184L (en) 1979-12-23
YU147179A (en) 1983-06-30
ES485182A1 (es) 1980-05-16
IL57627A (en) 1982-02-28
DE2962503D1 (en) 1982-05-27
NO792099L (no) 1979-12-28
AU4827579A (en) 1980-01-03
MX5687E (es) 1983-12-09
ES481799A1 (es) 1980-02-16
ES485181A1 (es) 1980-05-16
IE48355B1 (en) 1984-12-26
US4210659A (en) 1980-07-01
EP0006451B1 (fr) 1982-04-14
NZ190801A (en) 1984-05-31
PT69804A (de) 1979-07-01
IL57627A0 (en) 1979-10-31
CA1115280A (fr) 1981-12-29
DK262879A (da) 1979-12-24
FI791996A (fi) 1979-12-24
DK146389C (da) 1984-03-05
AU519287B2 (en) 1981-11-19
YU42307B (en) 1988-08-31
EP0006451A1 (fr) 1980-01-09
FI65068B (fi) 1983-11-30
JPH0127073B2 (fr) 1989-05-26
DK146389B (da) 1983-09-26
ZA793108B (en) 1981-02-25
JPS554392A (en) 1980-01-12
ES485180A1 (es) 1980-05-16
ATE853T1 (de) 1982-04-15

Similar Documents

Publication Publication Date Title
DE69420579T2 (de) 9-HYDROXY-PYRIDO [1,2-a] PYRIMIDIN-4-ON-ETHER-DERIVATE
EP0707571B1 (fr) Derives de la 3,5-dioxo-(2h,4h)-1,2,4-triazine comme 5ht1a ligands
EP0482939A1 (fr) Dérive d'isoquinolinone
EP0258755A1 (fr) Alpha-alkyl-4-amino-3-quinoléine-méthanols et 1-(4-aralkylamino-3-quinolyl)alkanones, un procédé pour leur synthèse et leur utilisation comme médicaments
JPH08269059A (ja) 新規のピリド[3,2−e]ピラジノン及びその製法、これを含有する抗喘息及び抗アレルギー作用を有する薬剤及びこの薬剤の製法
HU202211B (en) Process for producing new imidazoline derivatives and pharmaceutical compositions containing them as active components
DE2238504A1 (de) Propanolaminderivate
SK103093A3 (en) New active compounds
DE3878371T2 (de) Psychotropische bizyklische imide.
NO178968B (no) Analogifremgangsmåte for fremstilling av terapeutisk aktive aminopyrimidin-karboksamidderivater
FI65068C (fi) Foerfarande foer framstaellning av farmakologiskt vaerdefulla 7-fenyl-2,3-dihydro-imidazo(1,2-a)imidazoler och deras syraadditionssalter
DE69228307T2 (de) Imidazo(1,2-c)chinazolinderivate als antihypertensive und antidysurie
US5030639A (en) N-substituted-5,6-dimethoxy-1,2-benzisoxazole-3-propanamine and related compounds as analgesic and hypotensive agents
JPS58180484A (ja) 1−置換N−/8α−エルゴリニル/−N′,N′−ジエチルウレア及びその製造方法
CA1117944A (fr) Procedes de preparation de nouvelles piperazines disubstituees
JP2656184B2 (ja) 1−ピペラジニル−2−ブテンおよび2−ブチン、その製法およびその中間体
CA1202974A (fr) Procede de preparation de nouvelles benzothiopyranopyridinones et de leurs sels
FI68616B (fi) Foerfarande foer framstaellning av farmakologiskt vaerdefulla 1-alkyl-2-(n-allyl-n-(2,6-diklorfenyl)-amino)-2-imidazoliner
JPS6045878B2 (ja) N,n’−二置換環状ジアミン及び精神病治療用薬剤
NO128570B (fr)
CS274445B2 (en) Method of new trisubstituted amines production
HU187600B (en) Process for preparing 2-methyl-9,10-didehydro-ergolines
DE2131330A1 (de) Imidazo-[1,2-a]-benzimidazolderivate und Verfahren zur Herstellung derselben
LU86226A1 (fr) Nouvelles 8-acylaminoergolines,leur preparation,leur utilisation comme medicaments et les compositions pharmaceutiques les contenant
FI65428C (fi) Foerfarande foer framstaellning av farmakologiskt vaerdefulla 2-fenylamino-imidazolin(2) derivat

Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: C.H. BOEHRINGER SOHN