ES485180A1 - Procedimiento para la preparacion de nuevos imidazo (1,2-a) imidazoles - Google Patents

Procedimiento para la preparacion de nuevos imidazo (1,2-a) imidazoles

Info

Publication number
ES485180A1
ES485180A1 ES485180A ES485180A ES485180A1 ES 485180 A1 ES485180 A1 ES 485180A1 ES 485180 A ES485180 A ES 485180A ES 485180 A ES485180 A ES 485180A ES 485180 A1 ES485180 A1 ES 485180A1
Authority
ES
Spain
Prior art keywords
acid addition
addition salts
imidazo
imidazoles
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES485180A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CH Boehringer Sohn AG and Co KG
Original Assignee
CH Boehringer Sohn AG and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CH Boehringer Sohn AG and Co KG filed Critical CH Boehringer Sohn AG and Co KG
Publication of ES485180A1 publication Critical patent/ES485180A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Epoxy Resins (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

Procedimiento para la preparación de nuevos imidazo [1,2-a] imidazoles de la fórmula general **(Fórmula)** en que R1, R2 y R3, que pueden ser iguales o diferentes, significan un átomo de hidrógeno o un átomo de flúor, cloro o bromo, o un grupo metilo, metoxi o trifluorometilo, no debiendo ser hidrógeno al menos uno de los radicales R1, R2 ó R3, y R4 significa un átomo de hidrógeno o un grupo metilo, así como sus sales por adición de ácido.
ES485180A 1978-06-23 1979-10-19 Procedimiento para la preparacion de nuevos imidazo (1,2-a) imidazoles Expired ES485180A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19782827617 DE2827617A1 (de) 1978-06-23 1978-06-23 Neue imidazo eckige klammer auf 1,2- alpha eckige klammer zu imidazole, deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zu deren herstellung

Publications (1)

Publication Number Publication Date
ES485180A1 true ES485180A1 (es) 1980-05-16

Family

ID=6042588

Family Applications (4)

Application Number Title Priority Date Filing Date
ES481799A Expired ES481799A1 (es) 1978-06-23 1979-06-22 Procedimiento para la preparacion de nuevos imidazo 1,2-a imidazoles.
ES485181A Expired ES485181A1 (es) 1978-06-23 1979-10-19 Procedimiento para la preparacion de nuevos imidazo (1,2-a) imidazoles
ES485180A Expired ES485180A1 (es) 1978-06-23 1979-10-19 Procedimiento para la preparacion de nuevos imidazo (1,2-a) imidazoles
ES485182A Expired ES485182A1 (es) 1978-06-23 1979-10-19 Procedimiento para la preparacion de nuevos imidazo (1,2-a) imidazoles

Family Applications Before (2)

Application Number Title Priority Date Filing Date
ES481799A Expired ES481799A1 (es) 1978-06-23 1979-06-22 Procedimiento para la preparacion de nuevos imidazo 1,2-a imidazoles.
ES485181A Expired ES485181A1 (es) 1978-06-23 1979-10-19 Procedimiento para la preparacion de nuevos imidazo (1,2-a) imidazoles

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES485182A Expired ES485182A1 (es) 1978-06-23 1979-10-19 Procedimiento para la preparacion de nuevos imidazo (1,2-a) imidazoles

Country Status (18)

Country Link
US (1) US4210659A (es)
EP (1) EP0006451B1 (es)
JP (1) JPS554392A (es)
AT (1) ATE853T1 (es)
AU (1) AU519287B2 (es)
CA (1) CA1115280A (es)
DE (2) DE2827617A1 (es)
DK (1) DK146389C (es)
ES (4) ES481799A1 (es)
FI (1) FI65068C (es)
IE (1) IE48355B1 (es)
IL (1) IL57627A (es)
MX (1) MX5687E (es)
NO (1) NO151465C (es)
NZ (1) NZ190801A (es)
PT (1) PT69804A (es)
YU (1) YU42307B (es)
ZA (1) ZA793108B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3042636A1 (de) 1980-11-12 1982-06-16 C.H. Boehringer Sohn, 6507 Ingelheim Neue 7-(2,6-dibrom-4-methylphenyl)-2,3-dihydro-imidazo(1,2-a)imidazole, deren saeureadditionssalze, diese enhthaltende arzneimittel und verfahren zu deren herstellung
DE3124701A1 (de) * 1981-06-24 1983-01-13 Boehringer Ingelheim KG, 6507 Ingelheim Neue l-substituierte imidazo (1,2-a)imidazole, deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zu deren herstellung
US6414161B1 (en) * 2000-08-09 2002-07-02 Boehringer Ingelheim Pharmaceuticals, Inc. Synthesis of (R)-3-(4-Bromobenzyl)-1-(3,5-dichlorophenyl)-5-iodo-3-methyl-1-H-imidazo[1,2-a]imidazol-2-one
US6888004B2 (en) * 2001-01-26 2005-05-03 Bristol-Myers Squibb Company Imidazolyl derivatives as corticotropin releasing factor inhibitors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2393826A (en) * 1944-02-28 1946-01-29 Commercial Solvents Corp 1,3,7-triazabicyclo [3.3.0] octanes
DE2109524A1 (en) * 1971-03-01 1972-09-07 CH. Boehringer Sohn, 6507 Ingelheim 2,3-dihydr-dioxo-imidazo (1,2-a) imidazoles or pyrimidines - with hypotensive and neuroleptic activity
DE2118261A1 (de) * 1971-04-15 1972-11-02 C.H. Boehringer Sohn, 6507 Ingelheim Neue N-haltige Bicyclen, deren Säureadditionssalze sowie Verfahren zu deren Herstellung
US3865836A (en) * 1972-12-08 1975-02-11 Janssen Pharmaceutica Nv Bicyclic imidazoles

Also Published As

Publication number Publication date
DK262879A (da) 1979-12-24
NO151465C (no) 1985-04-17
MX5687E (es) 1983-12-09
FI791996A (fi) 1979-12-24
DK146389C (da) 1984-03-05
JPS554392A (en) 1980-01-12
AU4827579A (en) 1980-01-03
DE2827617A1 (de) 1980-01-10
AU519287B2 (en) 1981-11-19
DK146389B (da) 1983-09-26
YU147179A (en) 1983-06-30
PT69804A (de) 1979-07-01
CA1115280A (en) 1981-12-29
ES481799A1 (es) 1980-02-16
US4210659A (en) 1980-07-01
YU42307B (en) 1988-08-31
EP0006451B1 (de) 1982-04-14
IL57627A0 (en) 1979-10-31
EP0006451A1 (de) 1980-01-09
JPH0127073B2 (es) 1989-05-26
NO792099L (no) 1979-12-28
IE791184L (en) 1979-12-23
DE2962503D1 (en) 1982-05-27
ZA793108B (en) 1981-02-25
ATE853T1 (de) 1982-04-15
ES485182A1 (es) 1980-05-16
FI65068C (fi) 1984-03-12
NZ190801A (en) 1984-05-31
IE48355B1 (en) 1984-12-26
NO151465B (no) 1985-01-02
FI65068B (fi) 1983-11-30
IL57627A (en) 1982-02-28
ES485181A1 (es) 1980-05-16

Similar Documents

Publication Publication Date Title
FI810389L (fi) Foerfarande foer framstaellning av substituerade imidazolderivat
ES8506652A1 (es) Un metodo de preparar dihidrobenzopirrolbenzodiazepinas
DE3170937D1 (en) 2-(1,4-benzodioxan-2-ylalkyl) imidazoles, their preparation and pharmaceutical compositions containing them
SE7605819L (sv) Nya propargyl-2-fenylaminoimidazolin-(2), dess syraadditionssalter, lekemedel innehallande dessa och forfarande for framstellning derav
DE3060919D1 (en) Isoxazolecarboxylic acid anilides, their preparation, fungicidal compositions and process for combating fungi
ES8403125A1 (es) Procedimiento para la preparacion de nuevas piridobenzodiazepinonas.
ES485180A1 (es) Procedimiento para la preparacion de nuevos imidazo (1,2-a) imidazoles
ES8201140A1 (es) Procedimiento para la preparacion de 2-fenilamino-imidazoli nas-(2)sustituidas.
ES8202544A1 (es) Procedimiento para la preparacion de 2-fenilamino-imidazoli-nas -(2) sustituidas
ES481298A1 (es) Un procedimiento para preparar nuevos benzotiazo-derivados.
ATE29251T1 (de) Aminopyridincarbonsaeure-derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen.
ES8301991A1 (es) Procedimiento para la preparacion de 7-(2,6-dibromo-4-metil-fenil)-2,3-dihidro-imidazo 1,2-a, imidazoles.