FI65062C - Foerfarande foer framstaellning av 7,8-diklortetra-1,2,3,4-hydroisokinolin-hydroklorid - Google Patents

Foerfarande foer framstaellning av 7,8-diklortetra-1,2,3,4-hydroisokinolin-hydroklorid Download PDF

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Publication number
FI65062C
FI65062C FI792436A FI792436A FI65062C FI 65062 C FI65062 C FI 65062C FI 792436 A FI792436 A FI 792436A FI 792436 A FI792436 A FI 792436A FI 65062 C FI65062 C FI 65062C
Authority
FI
Finland
Prior art keywords
hydroxyethyl
hydrochloride
reaction
menetelmä
aluminum chloride
Prior art date
Application number
FI792436A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI792436A7 (fi
FI65062B (fi
Inventor
Bing Lun Lam
Wilford Lee Mendelson
Jr Charles Barton Spainhour
Original Assignee
Smithkline Beckman Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beckman Corp filed Critical Smithkline Beckman Corp
Publication of FI792436A7 publication Critical patent/FI792436A7/fi
Application granted granted Critical
Publication of FI65062B publication Critical patent/FI65062B/fi
Publication of FI65062C publication Critical patent/FI65062C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
FI792436A 1978-08-10 1979-08-06 Foerfarande foer framstaellning av 7,8-diklortetra-1,2,3,4-hydroisokinolin-hydroklorid FI65062C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US05/932,586 US4251660A (en) 1978-08-10 1978-08-10 Method for preparing tetrahydroisoquinolines
US93258678 1978-08-10

Publications (3)

Publication Number Publication Date
FI792436A7 FI792436A7 (fi) 1980-02-11
FI65062B FI65062B (fi) 1983-11-30
FI65062C true FI65062C (fi) 1984-03-12

Family

ID=25462546

Family Applications (1)

Application Number Title Priority Date Filing Date
FI792436A FI65062C (fi) 1978-08-10 1979-08-06 Foerfarande foer framstaellning av 7,8-diklortetra-1,2,3,4-hydroisokinolin-hydroklorid

Country Status (29)

Country Link
US (1) US4251660A (de)
EP (1) EP0008405B1 (de)
JP (1) JPS5524196A (de)
AR (1) AR220218A1 (de)
AT (1) ATE258T1 (de)
AU (1) AU522843B2 (de)
BG (1) BG32714A3 (de)
CA (1) CA1130290A (de)
CS (1) CS226006B2 (de)
DD (1) DD145532A5 (de)
DE (1) DE2961141D1 (de)
DK (1) DK330579A (de)
ES (1) ES483151A1 (de)
FI (1) FI65062C (de)
GR (1) GR69853B (de)
HU (1) HU178110B (de)
IE (1) IE48618B1 (de)
IL (1) IL57980A (de)
IN (1) IN152421B (de)
IT (1) IT1227791B (de)
MX (1) MX5581E (de)
NO (1) NO153807C (de)
NZ (1) NZ191227A (de)
PH (1) PH24441A (de)
PL (1) PL217684A1 (de)
PT (1) PT70029A (de)
RO (1) RO78160A (de)
SU (1) SU860698A3 (de)
ZA (1) ZA793308B (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0080779B1 (de) * 1981-11-27 1986-07-16 Smithkline Beckman Corporation 3-Benzazepine als Alpha-2-antagonisten
US4541954A (en) * 1984-09-05 1985-09-17 Smithkline Beckman Corporation Method for preparing 6-chloro-N-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2771468A (en) * 1954-02-19 1956-11-20 Sterling Drug Inc 4-aralkyl-3-morpholones, 4-aralkyl-3-homomorpholones and their preparation
US3947456A (en) * 1970-01-06 1976-03-30 Hoffman-La Roche Inc. Substituted 4-phenyl isoquinolines
US3752892A (en) * 1970-03-11 1973-08-14 Ciba Geigy Corp Anorexigenic tetrahydrobenzazepine derivative method and composition thereof

Also Published As

Publication number Publication date
DK330579A (da) 1980-02-11
ATE258T1 (de) 1981-10-15
EP0008405B1 (de) 1981-09-30
IT1227791B (it) 1991-05-07
IN152421B (de) 1984-01-07
AU4954779A (en) 1980-02-14
US4251660A (en) 1981-02-17
RO78160A (ro) 1982-02-01
EP0008405A3 (en) 1980-04-30
HU178110B (en) 1982-03-28
MX5581E (es) 1983-10-26
AR220218A1 (es) 1980-10-15
FI792436A7 (fi) 1980-02-11
JPS5524196A (en) 1980-02-21
NO153807C (no) 1986-05-28
IL57980A0 (en) 1979-12-30
ES483151A1 (es) 1980-04-16
GR69853B (de) 1982-07-19
PL217684A1 (de) 1980-06-16
NZ191227A (en) 1981-10-19
BG32714A3 (bg) 1982-09-15
PH24441A (en) 1990-06-25
NO792601L (no) 1980-02-12
NO153807B (no) 1986-02-17
SU860698A3 (ru) 1981-08-30
IE791534L (en) 1980-02-10
PT70029A (en) 1979-09-01
EP0008405A2 (de) 1980-03-05
DD145532A5 (de) 1980-12-17
DE2961141D1 (en) 1981-12-10
CS226006B2 (en) 1984-03-19
FI65062B (fi) 1983-11-30
ZA793308B (en) 1980-09-24
IT7924894A0 (it) 1979-08-02
CA1130290A (en) 1982-08-24
IL57980A (en) 1984-08-31
AU522843B2 (en) 1982-07-01
IE48618B1 (en) 1985-03-20

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Legal Events

Date Code Title Description
FD Application lapsed
MM Patent lapsed

Owner name: SMITHKLINE BECKMAN CORPORATION