FI63672C - Foerfarande foer framstaellning av en blandning av beklometasondipropionat och triklorfluormetan eller diklordifluormetan - Google Patents

Foerfarande foer framstaellning av en blandning av beklometasondipropionat och triklorfluormetan eller diklordifluormetan Download PDF

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Publication number
FI63672C
FI63672C FI801610A FI801610A FI63672C FI 63672 C FI63672 C FI 63672C FI 801610 A FI801610 A FI 801610A FI 801610 A FI801610 A FI 801610A FI 63672 C FI63672 C FI 63672C
Authority
FI
Finland
Prior art keywords
propellant
steroid
trichlorofluoromethane
added
particle size
Prior art date
Application number
FI801610A
Other languages
English (en)
Finnish (fi)
Other versions
FI801610A (fi
FI63672B (fi
Inventor
Paavo Tapani Tanskanen
Original Assignee
Orion Yhtymae Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orion Yhtymae Oy filed Critical Orion Yhtymae Oy
Priority to FI801610A priority Critical patent/FI63672C/fi
Priority to AT0179181A priority patent/AT380791B/de
Priority to GB8112683A priority patent/GB2076422B/en
Priority to CA000376540A priority patent/CA1162852A/en
Priority to PT72989A priority patent/PT72989B/pt
Priority to BE0/204802A priority patent/BE888822A/fr
Priority to FR8109719A priority patent/FR2482457A1/fr
Priority to CH3165/81A priority patent/CH647408A5/de
Priority to PL1981231220A priority patent/PL127872B1/pl
Priority to DK218481A priority patent/DK218481A/da
Priority to CS813676A priority patent/CS221831B2/cs
Priority to DD81230036A priority patent/DD158856A5/de
Priority to DE19813119745 priority patent/DE3119745A1/de
Priority to NO811686A priority patent/NO155429C/no
Priority to HU811405A priority patent/HU188093B/hu
Priority to SU813283353A priority patent/SU1184428A3/ru
Priority to ES502286A priority patent/ES8203606A1/es
Priority to NL8102457A priority patent/NL8102457A/nl
Priority to US06/265,333 priority patent/US4347236A/en
Priority to JP7433181A priority patent/JPS5716820A/ja
Priority to SE8103143A priority patent/SE437766B/sv
Publication of FI801610A publication Critical patent/FI801610A/fi
Application granted granted Critical
Publication of FI63672B publication Critical patent/FI63672B/fi
Publication of FI63672C publication Critical patent/FI63672C/fi

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K3/00—Materials not provided for elsewhere
    • C09K3/30—Materials not provided for elsewhere for aerosols

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Dispersion Chemistry (AREA)
  • Materials Engineering (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Otolaryngology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Steroid Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
FI801610A 1980-05-19 1980-05-19 Foerfarande foer framstaellning av en blandning av beklometasondipropionat och triklorfluormetan eller diklordifluormetan FI63672C (fi)

Priority Applications (21)

Application Number Priority Date Filing Date Title
FI801610A FI63672C (fi) 1980-05-19 1980-05-19 Foerfarande foer framstaellning av en blandning av beklometasondipropionat och triklorfluormetan eller diklordifluormetan
AT0179181A AT380791B (de) 1980-05-19 1981-04-21 Verfahren zur herstellung einer mischung eines antiinflammatorischen steroids und eines alspropellant verwendeten fluorchlorkohlenwasser- stoffs
GB8112683A GB2076422B (en) 1980-05-19 1981-04-24 Aerosols containing anti-inflammatory steroids
CA000376540A CA1162852A (en) 1980-05-19 1981-04-29 Process for the preparation of a mixture of an anti- inflammatory steroid and a fluoro-chloro-hydrocarbon to be used as a propellant
PT72989A PT72989B (en) 1980-05-19 1981-05-06 Process for the preparation of a mixture of an anti-inflammatory steroid and a fluor-chloro-hydrocarbon to be used as a propellant
FR8109719A FR2482457A1 (fr) 1980-05-19 1981-05-15 Procede pour la preparation d'un melange d'un steroide anti-inflammatoire et d'un fluorochlorohydrocarbure a utiliser comme agent propulseur
CH3165/81A CH647408A5 (de) 1980-05-19 1981-05-15 Verfahren zur herstellung einer mischung eines anti-inflammatorischen steroids und eines als treibmittel verwendeten fluorchlor-kohlenwasserstoffes.
BE0/204802A BE888822A (fr) 1980-05-19 1981-05-15 Procede pour la preparation d'un melange d'un steroide anti-inflammatoire et d'un fluorochlorohydrocarbure a utiliser comme agent propulseur
DD81230036A DD158856A5 (de) 1980-05-19 1981-05-18 Verfahren fuer die herstellung einer mischung eines antiinflammotorischen steroids und eines als propellant verwendeten fluorchlor-kohlenwasserstoffes
CS813676A CS221831B2 (en) 1980-05-19 1981-05-18 Method of preparation of the anti-inflammation steroid mixture of the type 9-chlore-11beta,17,21-trihydroxy-16beta-methyl-1,4-pregnadine-3,20-dion17,21-dipropionate pulverised on the size of particles mlesser than 5 min and fluorchlor-hydrocarbon utilized as actuating substace
PL1981231220A PL127872B1 (en) 1980-05-19 1981-05-18 Method of obtaining a mixture of anti-inflammatory steroid and halogenated hydrocarbon as a propellant
DE19813119745 DE3119745A1 (de) 1980-05-19 1981-05-18 Verfahren fuer die herstellung einer mischung eines antiinflammatorischen steroids und eines als propellant verwendeten fluorchlor-kohlenwasserstoffes
NO811686A NO155429C (no) 1980-05-19 1981-05-18 Fremgangsmaate for fremstilling av en blanding av et antiinflammatorisk steroid og et fluorklorhydrocarbondrivstoff.
HU811405A HU188093B (en) 1980-05-19 1981-05-18 Process for producing a compositions of antiflogistic steroid and fluorinated and chlorinated hydrocarbon as carrier
SU813283353A SU1184428A3 (ru) 1980-05-19 1981-05-18 Способ получени беклометазонадипропионата
ES502286A ES8203606A1 (es) 1980-05-19 1981-05-18 Procedimiento para la preparacion de una mezcla de un este- roide anti-inflamatorio y un fluoro-cloro-hidrocarburo para ser utilizado como propulsor
DK218481A DK218481A (da) 1980-05-19 1981-05-18 Fremgangsmaade til fremstilling af et antiinflammatorisk steroid og en som drivmiddel anvendelig fluorklorkulbrinte
NL8102457A NL8102457A (nl) 1980-05-19 1981-05-19 Werkwijze voor het bereiden van een mengsel van een ontstekingsremmend steroide en een fluorchloor-koolwaterstof als uitdrijfmiddel.
US06/265,333 US4347236A (en) 1980-05-19 1981-05-19 Process for the preparation of a mixture of an anti-inflammatory steroid and a fluoro-chloro-hydrocarbon to be used as a propellant
JP7433181A JPS5716820A (en) 1980-05-19 1981-05-19 Preparation of mixture comprising antiinflammatory steroid and chlorofluoro hydrocarbon as propellant
SE8103143A SE437766B (sv) 1980-05-19 1981-05-19 Forfarande for framstellning av en blandning av en antiinflammatorisk steroid och ett som drivemne anvendbart fluorkolvete

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI801610A FI63672C (fi) 1980-05-19 1980-05-19 Foerfarande foer framstaellning av en blandning av beklometasondipropionat och triklorfluormetan eller diklordifluormetan
FI801610 1980-05-19

Publications (3)

Publication Number Publication Date
FI801610A FI801610A (fi) 1981-11-20
FI63672B FI63672B (fi) 1983-04-29
FI63672C true FI63672C (fi) 1983-08-10

Family

ID=8513487

Family Applications (1)

Application Number Title Priority Date Filing Date
FI801610A FI63672C (fi) 1980-05-19 1980-05-19 Foerfarande foer framstaellning av en blandning av beklometasondipropionat och triklorfluormetan eller diklordifluormetan

Country Status (21)

Country Link
US (1) US4347236A (de)
JP (1) JPS5716820A (de)
AT (1) AT380791B (de)
BE (1) BE888822A (de)
CA (1) CA1162852A (de)
CH (1) CH647408A5 (de)
CS (1) CS221831B2 (de)
DD (1) DD158856A5 (de)
DE (1) DE3119745A1 (de)
DK (1) DK218481A (de)
ES (1) ES8203606A1 (de)
FI (1) FI63672C (de)
FR (1) FR2482457A1 (de)
GB (1) GB2076422B (de)
HU (1) HU188093B (de)
NL (1) NL8102457A (de)
NO (1) NO155429C (de)
PL (1) PL127872B1 (de)
PT (1) PT72989B (de)
SE (1) SE437766B (de)
SU (1) SU1184428A3 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR890000664B1 (ko) * 1981-10-19 1989-03-22 바리 안소니 뉴우샘 미분된 베클로메타손 디프로피오네이트 일수화물의 제조방법
WO1987005210A1 (en) * 1986-03-10 1987-09-11 Kurt Burghart Pharmaceutical preparation and process for preparing the same
JPH01156916A (ja) * 1987-09-25 1989-06-20 Ss Pharmaceut Co Ltd 肝疾患治療剤
US5736124A (en) * 1991-12-12 1998-04-07 Glaxo Group Limited Aerosol formulations containing P134a and particulate medicament
CA2125666C (en) * 1991-12-12 2002-07-16 Rachel Ann Akehurst Medicaments
IL104068A (en) 1991-12-12 1998-10-30 Glaxo Group Ltd Pharmaceutical preparations in a spray without surfactant containing 1, 1, 1, 2 tetrafluoroethane or 1,1,2,3,3 petafluor N propane as propellant
US5744123A (en) * 1991-12-12 1998-04-28 Glaxo Group Limited Aerosol formulations containing P134a and particulate medicaments
US5653962A (en) * 1991-12-12 1997-08-05 Glaxo Group Limited Aerosol formulations containing P134a and particulate medicaments
US5916540A (en) * 1994-10-24 1999-06-29 Glaxo Group Limited Aerosol formulations containing P134A and/or P227 and particulate medicament
US5658549A (en) * 1991-12-12 1997-08-19 Glaxo Group Limited Aerosol formulations containing propellant 134a and fluticasone propionate
US5674471A (en) * 1991-12-12 1997-10-07 Glaxo Group Limited Aerosol formulations containing P134a and salbutamol
US7101534B1 (en) 1991-12-18 2006-09-05 3M Innovative Properties Company Suspension aerosol formulations
ATE150296T1 (de) 1991-12-18 1997-04-15 Minnesota Mining & Mfg Aerosolzusammensetzungen für arzneimittelsuspensionen
US7105152B1 (en) 1991-12-18 2006-09-12 3M Innovative Properties Company Suspension aerosol formulations
GB9202519D0 (en) * 1992-02-06 1992-03-25 Glaxo Group Ltd Medicaments
US5376359A (en) * 1992-07-07 1994-12-27 Glaxo, Inc. Method of stabilizing aerosol formulations
MX9304585A (es) * 1992-07-31 1994-03-31 Glaxo Group Ltd Formulacion farmaceutica en aerosol, lata adecuada para liberar la formulacion e inhalador de dosis dosificada que comprende la lata.
GB0208742D0 (en) 2002-04-17 2002-05-29 Bradford Particle Design Ltd Particulate materials
US7582284B2 (en) 2002-04-17 2009-09-01 Nektar Therapeutics Particulate materials
JP5825757B2 (ja) 2007-02-11 2015-12-02 マップ・ファーマシューティカルズ・インコーポレイテッド 副作用プロファイルを最小限にしながら片頭痛の迅速な緩和を可能にするｄｈｅの治療上の投与方法
EP2935280A4 (de) 2012-12-21 2016-05-25 Map Pharmaceuticals Inc 8'-hydroxy-dihydroergotamin-verbindungen und -zusammensetzungen

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL289785A (de) * 1962-11-29
GB1429184A (en) * 1972-04-20 1976-03-24 Allen & Hanburys Ltd Physically anti-inflammatory steroids for use in aerosols
JPS531814A (en) * 1976-06-28 1978-01-10 Toshiba Corp Control unit of induction motor
US4225597A (en) * 1976-10-01 1980-09-30 Schering Corporation Beclomethasone dipropionate-hexane solvate and aerosols prepared therefrom
IT1121513B (it) * 1979-05-28 1986-04-02 Chiesi Farma Spa Processo per la conversione di umo steroide antiinfiammatorio in una forma suscettibile di essere somministarta come aerosol

Also Published As

Publication number Publication date
FR2482457A1 (fr) 1981-11-20
FR2482457B1 (de) 1985-01-04
DK218481A (da) 1981-11-20
ATA179181A (de) 1985-12-15
FI801610A (fi) 1981-11-20
DE3119745A1 (de) 1982-02-11
GB2076422A (en) 1981-12-02
PT72989A (en) 1981-06-01
SE437766B (sv) 1985-03-18
PL231220A1 (de) 1982-01-18
PL127872B1 (en) 1983-12-31
NO811686L (no) 1981-11-20
NL8102457A (nl) 1981-12-16
US4347236A (en) 1982-08-31
PT72989B (en) 1983-07-06
AT380791B (de) 1986-07-10
DD158856A5 (de) 1983-02-09
SE8103143L (sv) 1981-11-20
CH647408A5 (de) 1985-01-31
CS221831B2 (en) 1983-04-29
SU1184428A3 (ru) 1985-10-07
JPS5716820A (en) 1982-01-28
FI63672B (fi) 1983-04-29
ES502286A0 (es) 1982-04-01
ES8203606A1 (es) 1982-04-01
CA1162852A (en) 1984-02-28
BE888822A (fr) 1981-11-16
HU188093B (en) 1986-03-28
GB2076422B (en) 1983-12-14
NO155429C (no) 1987-04-01
NO155429B (no) 1986-12-22

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Owner name: ORION-YHTYMAE OY