FI61480C - Foerfarande foer framstaellning av antiemetiskt verksamma n-(1-substituerade-3-pyrrolidinyl)-1-naftalen- och -4-kinolinkarboxamider - Google Patents

Foerfarande foer framstaellning av antiemetiskt verksamma n-(1-substituerade-3-pyrrolidinyl)-1-naftalen- och -4-kinolinkarboxamider Download PDF

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Publication number
FI61480C
FI61480C FI753606A FI753606A FI61480C FI 61480 C FI61480 C FI 61480C FI 753606 A FI753606 A FI 753606A FI 753606 A FI753606 A FI 753606A FI 61480 C FI61480 C FI 61480C
Authority
FI
Finland
Prior art keywords
pyrrolidinyl
naphthalene
preparation
antiemetic
substituted
Prior art date
Application number
FI753606A
Other languages
English (en)
Finnish (fi)
Other versions
FI61480B (fi
FI753606A (es
Inventor
Jr Albert Duncan Cale
Original Assignee
Robins Co Inc A H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Robins Co Inc A H filed Critical Robins Co Inc A H
Publication of FI753606A publication Critical patent/FI753606A/fi
Publication of FI61480B publication Critical patent/FI61480B/fi
Application granted granted Critical
Publication of FI61480C publication Critical patent/FI61480C/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/14—Nitrogen atoms not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Otolaryngology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
FI753606A 1974-12-26 1975-12-19 Foerfarande foer framstaellning av antiemetiskt verksamma n-(1-substituerade-3-pyrrolidinyl)-1-naftalen- och -4-kinolinkarboxamider FI61480C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US05/536,514 US4002757A (en) 1974-12-26 1974-12-26 N-(1-substituted-3-pyrrolidinyl)-4-quinolinecarboxamides
US53651474 1974-12-26

Publications (3)

Publication Number Publication Date
FI753606A FI753606A (es) 1976-06-27
FI61480B FI61480B (fi) 1982-04-30
FI61480C true FI61480C (fi) 1982-08-10

Family

ID=24138812

Family Applications (1)

Application Number Title Priority Date Filing Date
FI753606A FI61480C (fi) 1974-12-26 1975-12-19 Foerfarande foer framstaellning av antiemetiskt verksamma n-(1-substituerade-3-pyrrolidinyl)-1-naftalen- och -4-kinolinkarboxamider

Country Status (18)

Country Link
US (3) US4002757A (es)
JP (2) JPS5191254A (es)
AU (1) AU499075B2 (es)
BE (1) BE836975A (es)
CA (1) CA1071636A (es)
CH (1) CH611603A5 (es)
DE (1) DE2558348A1 (es)
DK (1) DK138536B (es)
ES (1) ES443845A1 (es)
FI (1) FI61480C (es)
FR (1) FR2295744A1 (es)
GB (1) GB1537848A (es)
IE (1) IE43819B1 (es)
NL (1) NL7515084A (es)
NO (1) NO144670C (es)
PH (1) PH13883A (es)
SE (1) SE408417B (es)
ZA (1) ZA757972B (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4279822A (en) * 1972-04-03 1981-07-21 A. H. Robins Company, Inc. N-(1-Substituted-3-pyrrolidinyl)benzamides
US4002757A (en) * 1974-12-26 1977-01-11 A. H. Robins Company, Incorporated N-(1-substituted-3-pyrrolidinyl)-4-quinolinecarboxamides
US4143150A (en) * 1977-08-19 1979-03-06 A. H. Robins Company, Inc. Derivatives of oxanilic acid
DE3473442D1 (de) * 1983-01-21 1988-09-22 Alkaloida Vegyeszeti Gyar New alkyl diamine derivatives
US5210329A (en) * 1992-02-18 1993-05-11 General Electric Company Process for preparing bisphenol-A
US6673829B2 (en) 2001-09-14 2004-01-06 Novo Nordisk A/S Aminoazetidine,-pyrrolidine and -piperidine derivatives
EP1430027B1 (en) 2001-09-14 2010-09-01 High Point Pharmaceuticals, LLC Novel aminoazetidine, -pyrrolidine and -piperidine derivatives
AP2005003467A0 (en) 2003-06-17 2006-12-31 Pfizer N-pyrrolidin-3-YL-amide derivatives as serotonin and noradrenaline reuptake inhibitors.
US7348434B2 (en) * 2003-08-08 2008-03-25 Antony Bigot 4-substituted quinoline derivatives, method and intermediates for their preparation and pharmaceutical compositions containing them
WO2006064332A1 (en) * 2004-12-14 2006-06-22 Pfizer Limited N-pyrrolidin-3yl-amide derivatives as serotonin and noradrenalin re-uptake inhibitors
EP1828121A2 (en) * 2004-12-14 2007-09-05 Pfizer Limited N-pyrrolidin-3-yl-amide derivatives as serotonin and noradrenalin re-uptake inhibitors
EP1828122A2 (en) * 2004-12-16 2007-09-05 Pfizer Limited N-pyrrolidin-3-yl-amide derivatives as serotonin and noradrenalin re-uptake inhibitors
CN101679357A (zh) * 2007-05-09 2010-03-24 辉瑞大药厂 取代的杂环衍生物及其组合物和作为抗菌剂的药物用途

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1825623A (en) * 1931-09-29 Oonhohachzn
DE67123C (de) * L. THOMAS in Montegnee-les-Siege, Belgien Handdrehbohrmaschine für Gruben und Steinbrüche
US3133061A (en) * 1962-11-13 1964-05-12 Sterling Drug Inc Piperidine carboxamides and derivatives thereof
US3342826A (en) * 1964-01-13 1967-09-19 Ile De France Heterocyclic aminoalkyl benzamides
GB1364231A (en) * 1968-12-23 1974-08-21 Robins Co Inc A H N-/1-substituted-3-pyrrolidinyl/benzamides and thiobenzamides
US3577440A (en) * 1968-12-23 1971-05-04 Robins Co Inc A H 1-substituted-3-amido-pyrrolidines
US3829434A (en) * 1972-11-10 1974-08-13 Pfizer Piperidinesulfonylurea derivatives
US4002757A (en) * 1974-12-26 1977-01-11 A. H. Robins Company, Incorporated N-(1-substituted-3-pyrrolidinyl)-4-quinolinecarboxamides

Also Published As

Publication number Publication date
NO144670B (no) 1981-07-06
JPS619314B2 (es) 1986-03-22
BE836975A (fr) 1976-04-16
FR2295744A1 (fr) 1976-07-23
ZA757972B (en) 1976-12-29
ES443845A1 (es) 1977-04-16
DK589075A (es) 1976-06-27
AU499075B2 (en) 1979-04-05
PH13883A (en) 1980-10-27
JPS611426B2 (es) 1986-01-17
JPS60248684A (ja) 1985-12-09
DK138536B (da) 1978-09-25
AU8755075A (en) 1977-06-23
NO144670C (no) 1981-10-14
IE43819B1 (en) 1981-06-03
CH611603A5 (es) 1979-06-15
SE7514374L (sv) 1976-06-28
JPS5191254A (en) 1976-08-10
NO754376L (es) 1976-06-29
DK138536C (es) 1979-03-05
US4087428A (en) 1978-05-02
DE2558348A1 (de) 1976-07-08
SE408417B (sv) 1979-06-11
GB1537848A (en) 1979-01-04
FR2295744B1 (es) 1978-07-28
FI61480B (fi) 1982-04-30
NL7515084A (nl) 1976-06-29
FI753606A (es) 1976-06-27
IE43819L (en) 1976-06-26
US4073796A (en) 1978-02-14
CA1071636A (en) 1980-02-12
US4002757A (en) 1977-01-11

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Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: A.H. ROBINS COMPANY, INCORPORATED