FI59676C - Foerfarande foer teknisk framstaellning av foerbeskiktade objektglas - Google Patents
Foerfarande foer teknisk framstaellning av foerbeskiktade objektglas Download PDFInfo
- Publication number
- FI59676C FI59676C FI760910A FI760910A FI59676C FI 59676 C FI59676 C FI 59676C FI 760910 A FI760910 A FI 760910A FI 760910 A FI760910 A FI 760910A FI 59676 C FI59676 C FI 59676C
- Authority
- FI
- Finland
- Prior art keywords
- slides
- dye
- staining
- purple
- nozzle
- Prior art date
Links
- 239000000975 dye Substances 0.000 description 26
- 239000000243 solution Substances 0.000 description 17
- 238000000034 method Methods 0.000 description 15
- 239000007921 spray Substances 0.000 description 15
- 238000010186 staining Methods 0.000 description 14
- 210000004369 blood Anatomy 0.000 description 6
- 239000008280 blood Substances 0.000 description 6
- 238000001035 drying Methods 0.000 description 6
- 210000003743 erythrocyte Anatomy 0.000 description 6
- 238000005507 spraying Methods 0.000 description 6
- 239000000203 mixture Substances 0.000 description 5
- 239000002904 solvent Substances 0.000 description 5
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 4
- 210000000265 leukocyte Anatomy 0.000 description 4
- 239000007788 liquid Substances 0.000 description 4
- 238000004806 packaging method and process Methods 0.000 description 4
- 238000002360 preparation method Methods 0.000 description 4
- 210000001995 reticulocyte Anatomy 0.000 description 4
- 239000000126 substance Substances 0.000 description 4
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 3
- 238000006243 chemical reaction Methods 0.000 description 3
- 239000010408 film Substances 0.000 description 3
- 239000011521 glass Substances 0.000 description 3
- CXKWCBBOMKCUKX-UHFFFAOYSA-M methylene blue Chemical compound [Cl-].C1=CC(N(C)C)=CC2=[S+]C3=CC(N(C)C)=CC=C3N=C21 CXKWCBBOMKCUKX-UHFFFAOYSA-M 0.000 description 3
- 239000004094 surface-active agent Substances 0.000 description 3
- 238000005406 washing Methods 0.000 description 3
- 238000009736 wetting Methods 0.000 description 3
- 239000000654 additive Substances 0.000 description 2
- 239000007864 aqueous solution Substances 0.000 description 2
- 210000000981 epithelium Anatomy 0.000 description 2
- 238000007654 immersion Methods 0.000 description 2
- 239000003350 kerosene Substances 0.000 description 2
- 210000004698 lymphocyte Anatomy 0.000 description 2
- 229910052751 metal Inorganic materials 0.000 description 2
- 239000002184 metal Substances 0.000 description 2
- 239000002245 particle Substances 0.000 description 2
- 238000003860 storage Methods 0.000 description 2
- HNONEKILPDHFOL-UHFFFAOYSA-M tolonium chloride Chemical compound [Cl-].C1=C(C)C(N)=CC2=[S+]C3=CC(N(C)C)=CC=C3N=C21 HNONEKILPDHFOL-UHFFFAOYSA-M 0.000 description 2
- 230000032258 transport Effects 0.000 description 2
- 210000002700 urine Anatomy 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 1
- 235000011449 Rosa Nutrition 0.000 description 1
- 229920002472 Starch Polymers 0.000 description 1
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 description 1
- GLNADSQYFUSGOU-GPTZEZBUSA-J Trypan blue Chemical compound [Na+].[Na+].[Na+].[Na+].C1=C(S([O-])(=O)=O)C=C2C=C(S([O-])(=O)=O)C(/N=N/C3=CC=C(C=C3C)C=3C=C(C(=CC=3)\N=N\C=3C(=CC4=CC(=CC(N)=C4C=3O)S([O-])(=O)=O)S([O-])(=O)=O)C)=C(O)C2=C1N GLNADSQYFUSGOU-GPTZEZBUSA-J 0.000 description 1
- 206010046543 Urinary incontinence Diseases 0.000 description 1
- UEJQQMLXZQUJHF-UHFFFAOYSA-L [K+].[I+].[I-].[I-] Chemical compound [K+].[I+].[I-].[I-] UEJQQMLXZQUJHF-UHFFFAOYSA-L 0.000 description 1
- 239000012932 acetate dye Substances 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 238000007605 air drying Methods 0.000 description 1
- 230000003466 anti-cipated effect Effects 0.000 description 1
- 239000003146 anticoagulant agent Substances 0.000 description 1
- 229940127219 anticoagulant drug Drugs 0.000 description 1
- 210000003651 basophil Anatomy 0.000 description 1
- FAJDWNKDRFAWLS-UHFFFAOYSA-N benzyl-[9-(diethylamino)benzo[a]phenoxazin-5-ylidene]azanium;chloride Chemical compound [Cl-].O1C2=CC(N(CC)CC)=CC=C2N=C(C2=CC=CC=C22)C1=CC2=[NH+]CC1=CC=CC=C1 FAJDWNKDRFAWLS-UHFFFAOYSA-N 0.000 description 1
- 238000004820 blood count Methods 0.000 description 1
- 239000006172 buffering agent Substances 0.000 description 1
- 150000001721 carbon Chemical class 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- IQFVPQOLBLOTPF-HKXUKFGYSA-L congo red Chemical compound [Na+].[Na+].C1=CC=CC2=C(N)C(/N=N/C3=CC=C(C=C3)C3=CC=C(C=C3)/N=N/C3=C(C4=CC=CC=C4C(=C3)S([O-])(=O)=O)N)=CC(S([O-])(=O)=O)=C21 IQFVPQOLBLOTPF-HKXUKFGYSA-L 0.000 description 1
- ZXJXZNDDNMQXFV-UHFFFAOYSA-M crystal violet Chemical compound [Cl-].C1=CC(N(C)C)=CC=C1[C+](C=1C=CC(=CC=1)N(C)C)C1=CC=C(N(C)C)C=C1 ZXJXZNDDNMQXFV-UHFFFAOYSA-M 0.000 description 1
- 238000002845 discoloration Methods 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
- 238000004043 dyeing Methods 0.000 description 1
- 210000003979 eosinophil Anatomy 0.000 description 1
- 150000002148 esters Chemical class 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 230000002496 gastric effect Effects 0.000 description 1
- 229960001235 gentian violet Drugs 0.000 description 1
- 210000004276 hyalin Anatomy 0.000 description 1
- 238000003384 imaging method Methods 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 230000003834 intracellular effect Effects 0.000 description 1
- 150000002576 ketones Chemical class 0.000 description 1
- 238000002372 labelling Methods 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 239000002609 medium Substances 0.000 description 1
- VHGXRGXCDVQIKS-KRWDZBQOSA-N methyl (2s)-3-(4-methylphenyl)sulfonyloxy-2-(phenylmethoxycarbonylamino)propanoate Chemical compound C([C@@H](C(=O)OC)NC(=O)OCC=1C=CC=CC=1)OS(=O)(=O)C1=CC=C(C)C=C1 VHGXRGXCDVQIKS-KRWDZBQOSA-N 0.000 description 1
- 210000001616 monocyte Anatomy 0.000 description 1
- 210000003097 mucus Anatomy 0.000 description 1
- 210000000440 neutrophil Anatomy 0.000 description 1
- 238000012856 packing Methods 0.000 description 1
- 238000010422 painting Methods 0.000 description 1
- 239000003208 petroleum Substances 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 235000010483 polyoxyethylene sorbitan monopalmitate Nutrition 0.000 description 1
- 239000000249 polyoxyethylene sorbitan monopalmitate Substances 0.000 description 1
- 229920000136 polysorbate Polymers 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 230000002335 preservative effect Effects 0.000 description 1
- 210000003660 reticulum Anatomy 0.000 description 1
- OARRHUQTFTUEOS-UHFFFAOYSA-N safranin Chemical compound [Cl-].C=12C=C(N)C(C)=CC2=NC2=CC(C)=C(N)C=C2[N+]=1C1=CC=CC=C1 OARRHUQTFTUEOS-UHFFFAOYSA-N 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 239000013049 sediment Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 229910021653 sulphate ion Inorganic materials 0.000 description 1
- 239000010409 thin film Substances 0.000 description 1
- 229950003937 tolonium Drugs 0.000 description 1
- 230000002485 urinary effect Effects 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
- G01N1/31—Apparatus therefor
- G01N1/312—Apparatus therefor for samples mounted on planar substrates
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Biomedical Technology (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Sampling And Sample Adjustment (AREA)
- Application Of Or Painting With Fluid Materials (AREA)
- Surface Treatment Of Glass (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Materials For Photolithography (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2515869A DE2515869C3 (de) | 1975-04-11 | 1975-04-11 | Verfahren und Vorrichtung zur Herstellung von vorbeschichteten Objektträgern |
| DE2515869 | 1975-04-11 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| FI760910A FI760910A (it) | 1976-10-12 |
| FI59676B FI59676B (fi) | 1981-05-29 |
| FI59676C true FI59676C (fi) | 1981-09-10 |
Family
ID=5943617
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI760910A FI59676C (fi) | 1975-04-11 | 1976-04-05 | Foerfarande foer teknisk framstaellning av foerbeskiktade objektglas |
Country Status (21)
| Country | Link |
|---|---|
| US (2) | US4103041A (it) |
| JP (1) | JPS51135920A (it) |
| AR (1) | AR206748A1 (it) |
| AT (1) | AT342889B (it) |
| AU (1) | AU501167B2 (it) |
| BE (1) | BE840453A (it) |
| CA (1) | CA1069389A (it) |
| CH (1) | CH598608A5 (it) |
| CS (1) | CS222662B2 (it) |
| DD (1) | DD123627A5 (it) |
| DE (1) | DE2515869C3 (it) |
| DK (1) | DK148476A (it) |
| ES (1) | ES446834A1 (it) |
| FI (1) | FI59676C (it) |
| FR (1) | FR2307281A1 (it) |
| GB (1) | GB1480575A (it) |
| HU (1) | HU176480B (it) |
| IE (1) | IE42551B1 (it) |
| IT (1) | IT1059618B (it) |
| NL (1) | NL7603627A (it) |
| SE (1) | SE420354B (it) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4190472A (en) * | 1977-09-28 | 1980-02-26 | Alex Slonicki | Automated system for the application of coverglasses on histological and cytological slides |
| DE2826363C2 (de) * | 1978-06-16 | 1984-08-16 | Merck Patent Gmbh, 6100 Darmstadt | Deckfolie zur Verwendung in mikroskopischen Färbeverfahren und Verfahren zu ihrer Herstellung |
| US4248821A (en) * | 1979-07-25 | 1981-02-03 | Dellen Adrian F Van | Method and device for embedding a specimen for microscopic examination |
| US4523826A (en) * | 1980-12-15 | 1985-06-18 | University Of Pittsburgh | Autoradiography apparatus including a slide rack |
| WO1992019952A1 (en) * | 1991-05-07 | 1992-11-12 | Wescor, Inc. | Improved staining method for histology and cytology specimens |
| US5439649A (en) * | 1993-09-29 | 1995-08-08 | Biogenex Laboratories | Automated staining apparatus |
| US5817032A (en) | 1996-05-14 | 1998-10-06 | Biopath Automation Llc. | Means and method for harvesting and handling tissue samples for biopsy analysis |
| AU2777199A (en) * | 1998-02-19 | 1999-09-06 | Edvotek | Articles of manufacture and methods for staining biomolecules |
| US6562299B1 (en) | 1998-09-18 | 2003-05-13 | Cytyc Corporation | Method and apparatus for preparing cytological specimens |
| US6572824B1 (en) * | 1998-09-18 | 2003-06-03 | Cytyc Corporation | Method and apparatus for preparing cytological specimens |
| US20070166834A1 (en) * | 1998-10-05 | 2007-07-19 | Biopath Automation, L.L.C. | Apparatus and method for harvesting and handling tissue samples for biopsy analysis |
| US7179424B2 (en) * | 2002-09-26 | 2007-02-20 | Biopath Automation, L.L.C. | Cassette for handling and holding tissue samples during processing, embedding and microtome procedures, and methods therefor |
| EP2002894B1 (en) * | 2002-09-26 | 2011-12-28 | BioPath Automation, L.L.C. | Staging tool for tissue samples and method of staging a tissue sample cassette |
| BR0215830A (pt) * | 2002-09-26 | 2005-06-07 | Biopath Automation Llc | Máquinas e métodos automatizados para envolver amostras de tecido nos suportes seccionáveis de micrótomo |
| US20070116612A1 (en) * | 2005-11-02 | 2007-05-24 | Biopath Automation, L.L.C. | Prefix tissue cassette |
| US20080102526A1 (en) * | 2006-10-30 | 2008-05-01 | Sysmex Corporation | Reagent, reagent kit and analyzing method |
| AU2007332770B2 (en) * | 2006-12-12 | 2013-09-05 | Biopath Automation, L.L.C. | Biopsy support with sectionable resilient cellular material |
| EP2244987A4 (en) * | 2008-02-22 | 2013-07-31 | Materials And Technologies Corp | HIGH EFFICIENCY MONOFACE WET ENGRAVING AND WET TREATMENT APPARATUS AND METHOD |
| CA2748542A1 (en) * | 2008-12-30 | 2010-07-08 | Biopath Automation, L.L.C. | Systems and methods for processing tissue samples for histopathology |
| DK2389116T3 (en) | 2009-01-22 | 2018-02-12 | Biopath Automation Llc | BIOPSY SUPPORT TO ORIENT TESTS FOR SECTION IN A MICROTOM |
| WO2012064873A1 (en) | 2010-11-10 | 2012-05-18 | Constitution Medical, Inc. | Automated systems and methods for preparing biological specimens for examination |
| CN103827654B (zh) * | 2011-09-13 | 2017-06-13 | 皇家飞利浦有限公司 | 用于制备进行检查的细胞学样品的系统和试剂盒 |
| ES2939124T3 (es) | 2013-04-05 | 2023-04-19 | Roche Diagnostics Hematology Inc | Sistemas y procedimientos automatizados para preparar muestras biológicas para su examen |
| US20220317434A1 (en) * | 2021-04-03 | 2022-10-06 | Keith Louis De Santo | Micro-organism identification using light microscopes, conveyor belts, static electricity, artificial intelligence and machine learning algorithms |
| CN113405878B (zh) * | 2021-08-04 | 2023-09-29 | 深圳明志医学检验实验室 | 一种适用于医疗病理检测用血液临时装片制作的辅助设备 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3004875A (en) * | 1957-11-22 | 1961-10-17 | Pittsburgh Plate Glass Co | Coating glass sheets |
| US3056696A (en) * | 1958-06-04 | 1962-10-02 | Libbey Owens Ford Glass Co | Ultrathin films |
| US3107058A (en) * | 1960-01-07 | 1963-10-15 | Vllbiss Company De | Atomizer for preparing microscopic slides |
| US3352280A (en) * | 1964-05-01 | 1967-11-14 | Coulter Electronics | Centrifugal apparatus for slide staining |
| US3495926A (en) * | 1966-11-02 | 1970-02-17 | John F Naz | Method and apparatus for staining microslides |
| US3667896A (en) * | 1968-10-21 | 1972-06-06 | Miles Lab | Applying film of stain to tissue mounted on a moving slide |
| US3796594A (en) * | 1970-10-30 | 1974-03-12 | Gen Electric | Stain coated slides for differentially staining blood |
| US3906120A (en) * | 1970-10-30 | 1975-09-16 | Gen Electric | Method for preparing slides for blood evaluation |
| US3837795A (en) * | 1971-11-05 | 1974-09-24 | Biomatics Instr Corp | Method and apparatus for staining slides |
| US3900641A (en) * | 1972-01-21 | 1975-08-19 | Lancaster Products Company | Method of forming decorator panels |
| US3834874A (en) * | 1972-10-18 | 1974-09-10 | Gen Electric | Detection of malarial parasites in blood |
| US3853092A (en) * | 1973-10-25 | 1974-12-10 | Corning Glass Works | Apparatus for nutating and staining a microscope slide |
| FR2263502B1 (it) * | 1974-03-06 | 1976-12-10 | Ass Ctre Transfusion San | |
| US3932681A (en) * | 1974-03-11 | 1976-01-13 | Corning Glass Works | Ceramic masking method |
| US4089989A (en) * | 1975-04-04 | 1978-05-16 | White Ronald D | Method for preparing microscope slides by rotating during coating |
-
1975
- 1975-04-11 DE DE2515869A patent/DE2515869C3/de not_active Expired
-
1976
- 1976-01-01 AR AR262782A patent/AR206748A1/es active
- 1976-02-27 SE SE7602727A patent/SE420354B/xx unknown
- 1976-03-31 US US05/672,574 patent/US4103041A/en not_active Expired - Lifetime
- 1976-03-31 DK DK148476A patent/DK148476A/da not_active IP Right Cessation
- 1976-04-05 HU HU76BO1608A patent/HU176480B/hu unknown
- 1976-04-05 AU AU12676/76A patent/AU501167B2/en not_active Expired
- 1976-04-05 FI FI760910A patent/FI59676C/fi not_active IP Right Cessation
- 1976-04-06 GB GB13852/76A patent/GB1480575A/en not_active Expired
- 1976-04-06 DD DD192222A patent/DD123627A5/xx unknown
- 1976-04-07 CH CH439276A patent/CH598608A5/xx not_active IP Right Cessation
- 1976-04-07 BE BE165899A patent/BE840453A/xx not_active IP Right Cessation
- 1976-04-07 CS CS762301A patent/CS222662B2/cs unknown
- 1976-04-07 NL NL7603627A patent/NL7603627A/xx not_active Application Discontinuation
- 1976-04-07 IT IT22061/76A patent/IT1059618B/it active
- 1976-04-07 CA CA249,727A patent/CA1069389A/en not_active Expired
- 1976-04-09 IE IE751/76A patent/IE42551B1/en unknown
- 1976-04-09 FR FR7610488A patent/FR2307281A1/fr active Granted
- 1976-04-09 ES ES446834A patent/ES446834A1/es not_active Expired
- 1976-04-09 AT AT261976A patent/AT342889B/de not_active IP Right Cessation
- 1976-04-12 JP JP51041172A patent/JPS51135920A/ja active Pending
-
1978
- 1978-04-24 US US05/899,666 patent/US4224277A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| FI760910A (it) | 1976-10-12 |
| FR2307281B1 (it) | 1981-09-11 |
| HU176480B (en) | 1981-03-28 |
| US4224277A (en) | 1980-09-23 |
| US4103041A (en) | 1978-07-25 |
| SE420354B (sv) | 1981-09-28 |
| ES446834A1 (es) | 1977-06-01 |
| CA1069389A (en) | 1980-01-08 |
| AT342889B (de) | 1978-04-25 |
| DE2515869B2 (de) | 1979-03-15 |
| SE7602727L (sv) | 1976-10-12 |
| NL7603627A (nl) | 1976-10-13 |
| AU501167B2 (en) | 1979-06-14 |
| GB1480575A (en) | 1977-07-20 |
| ATA261976A (de) | 1977-08-15 |
| AU1267676A (en) | 1977-10-13 |
| JPS51135920A (en) | 1976-11-25 |
| DD123627A5 (it) | 1977-01-05 |
| IT1059618B (it) | 1982-06-21 |
| DE2515869C3 (de) | 1979-11-08 |
| IE42551L (en) | 1976-10-11 |
| IE42551B1 (en) | 1980-08-27 |
| BE840453A (fr) | 1976-10-07 |
| FI59676B (fi) | 1981-05-29 |
| FR2307281A1 (fr) | 1976-11-05 |
| DE2515869A1 (de) | 1976-10-21 |
| CH598608A5 (it) | 1978-05-12 |
| CS222662B2 (en) | 1983-07-29 |
| DK148476A (da) | 1976-10-12 |
| AR206748A1 (es) | 1976-08-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM | Patent lapsed |
Owner name: BOEHRINGER MANNHEIM GMBH |