FI59535C - Foerfarande att tillverka levande virusvaccin foer newcastle-sjukdom - Google Patents
Foerfarande att tillverka levande virusvaccin foer newcastle-sjukdom Download PDFInfo
- Publication number
- FI59535C FI59535C FI781233A FI781233A FI59535C FI 59535 C FI59535 C FI 59535C FI 781233 A FI781233 A FI 781233A FI 781233 A FI781233 A FI 781233A FI 59535 C FI59535 C FI 59535C
- Authority
- FI
- Finland
- Prior art keywords
- strain
- vaccine
- newcastle disease
- newcastle
- lasota
- Prior art date
Links
- 229960005486 vaccine Drugs 0.000 claims description 41
- 241000711404 Avian avulavirus 1 Species 0.000 claims description 24
- 239000000443 aerosol Substances 0.000 claims description 18
- 208000015181 infectious disease Diseases 0.000 claims description 16
- 241000287828 Gallus gallus Species 0.000 claims description 14
- 241000700605 Viruses Species 0.000 claims description 14
- 230000002458 infectious effect Effects 0.000 claims description 13
- 238000000034 method Methods 0.000 claims description 8
- 208000010359 Newcastle Disease Diseases 0.000 claims description 7
- 210000002950 fibroblast Anatomy 0.000 claims description 6
- 210000001161 mammalian embryo Anatomy 0.000 claims description 6
- 230000002238 attenuated effect Effects 0.000 claims description 5
- 238000011156 evaluation Methods 0.000 claims description 4
- 238000002360 preparation method Methods 0.000 claims description 4
- 206010057040 Temperature intolerance Diseases 0.000 claims description 3
- 230000000052 comparative effect Effects 0.000 claims description 3
- 230000000694 effects Effects 0.000 claims description 3
- 230000008543 heat sensitivity Effects 0.000 claims description 3
- 239000003381 stabilizer Substances 0.000 claims description 2
- 229940079593 drug Drugs 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 230000035601 cold sensitivity Effects 0.000 claims 1
- 230000005855 radiation Effects 0.000 claims 1
- 230000006641 stabilisation Effects 0.000 claims 1
- 238000011105 stabilization Methods 0.000 claims 1
- 235000013330 chicken meat Nutrition 0.000 description 13
- 102000004142 Trypsin Human genes 0.000 description 8
- 108090000631 Trypsin Proteins 0.000 description 8
- 235000013601 eggs Nutrition 0.000 description 8
- 239000012588 trypsin Substances 0.000 description 8
- 241001465754 Metazoa Species 0.000 description 7
- 210000002966 serum Anatomy 0.000 description 7
- 238000004113 cell culture Methods 0.000 description 5
- 101710154606 Hemagglutinin Proteins 0.000 description 4
- 101710093908 Outer capsid protein VP4 Proteins 0.000 description 4
- 101710135467 Outer capsid protein sigma-1 Proteins 0.000 description 4
- 101710176177 Protein A56 Proteins 0.000 description 4
- 210000004027 cell Anatomy 0.000 description 4
- 239000000185 hemagglutinin Substances 0.000 description 4
- 239000007791 liquid phase Substances 0.000 description 4
- 230000035945 sensitivity Effects 0.000 description 4
- 238000002255 vaccination Methods 0.000 description 4
- 230000001717 pathogenic effect Effects 0.000 description 3
- 230000007918 pathogenicity Effects 0.000 description 3
- 239000000243 solution Substances 0.000 description 3
- 239000004475 Arginine Substances 0.000 description 2
- 241000271566 Aves Species 0.000 description 2
- 239000001888 Peptone Substances 0.000 description 2
- 108010080698 Peptones Proteins 0.000 description 2
- 229930006000 Sucrose Natural products 0.000 description 2
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 2
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 description 2
- MCWXGJITAZMZEV-UHFFFAOYSA-N dimethoate Chemical compound CNC(=O)CSP(=S)(OC)OC MCWXGJITAZMZEV-UHFFFAOYSA-N 0.000 description 2
- 210000002308 embryonic cell Anatomy 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 239000011521 glass Substances 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 230000035772 mutation Effects 0.000 description 2
- 235000019319 peptone Nutrition 0.000 description 2
- 244000144977 poultry Species 0.000 description 2
- 235000013594 poultry meat Nutrition 0.000 description 2
- 239000005720 sucrose Substances 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 108091003079 Bovine Serum Albumin Proteins 0.000 description 1
- 208000035473 Communicable disease Diseases 0.000 description 1
- ODKSFYDXXFIFQN-BYPYZUCNSA-P L-argininium(2+) Chemical compound NC(=[NH2+])NCCC[C@H]([NH3+])C(O)=O ODKSFYDXXFIFQN-BYPYZUCNSA-P 0.000 description 1
- GRYLNZFGIOXLOG-UHFFFAOYSA-N Nitric acid Chemical compound O[N+]([O-])=O GRYLNZFGIOXLOG-UHFFFAOYSA-N 0.000 description 1
- 241000644027 Perideridia lemmonii Species 0.000 description 1
- 238000010306 acid treatment Methods 0.000 description 1
- 238000010171 animal model Methods 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 206010006451 bronchitis Diseases 0.000 description 1
- 238000012512 characterization method Methods 0.000 description 1
- 238000012258 culturing Methods 0.000 description 1
- 230000016396 cytokine production Effects 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 239000003651 drinking water Substances 0.000 description 1
- 235000020188 drinking water Nutrition 0.000 description 1
- 241001493065 dsRNA viruses Species 0.000 description 1
- 239000003889 eye drop Substances 0.000 description 1
- 229940012356 eye drops Drugs 0.000 description 1
- 239000012894 fetal calf serum Substances 0.000 description 1
- 238000002649 immunization Methods 0.000 description 1
- 230000003053 immunization Effects 0.000 description 1
- 230000002163 immunogen Effects 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 238000011534 incubation Methods 0.000 description 1
- 230000008774 maternal effect Effects 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 239000007923 nasal drop Substances 0.000 description 1
- 229940100662 nasal drops Drugs 0.000 description 1
- 229910017604 nitric acid Inorganic materials 0.000 description 1
- 230000008520 organization Effects 0.000 description 1
- 239000008063 pharmaceutical solvent Substances 0.000 description 1
- 208000023504 respiratory system disease Diseases 0.000 description 1
- 238000011076 safety test Methods 0.000 description 1
- 230000000087 stabilizing effect Effects 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 230000008542 thermal sensitivity Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/155—Paramyxoviridae, e.g. parainfluenza virus
- A61K39/17—Newcastle disease virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5254—Virus avirulent or attenuated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
- A61K2039/541—Mucosal route
- A61K2039/544—Mucosal route to the airways
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
- A61K2039/552—Veterinary vaccine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18111—Avulavirus, e.g. Newcastle disease virus
- C12N2760/18134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Pulmonology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| BE853923 | 1977-04-25 | ||
| BE853923 | 1977-04-25 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| FI781233A7 FI781233A7 (fi) | 1978-10-26 |
| FI59535B FI59535B (fi) | 1981-05-29 |
| FI59535C true FI59535C (fi) | 1981-09-10 |
Family
ID=3861522
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI781233A FI59535C (fi) | 1977-04-25 | 1978-04-21 | Foerfarande att tillverka levande virusvaccin foer newcastle-sjukdom |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US4235876A (de) |
| AR (1) | AR218304A1 (de) |
| AT (1) | AT358166B (de) |
| BE (1) | BE853923A (de) |
| CA (1) | CA1113860A (de) |
| CH (1) | CH641047A5 (de) |
| DE (1) | DE2817891A1 (de) |
| DK (1) | DK160878A (de) |
| FI (1) | FI59535C (de) |
| FR (1) | FR2388564A1 (de) |
| GB (1) | GB1593567A (de) |
| HU (1) | HU179290B (de) |
| IE (1) | IE46943B1 (de) |
| IL (1) | IL54390A (de) |
| IT (1) | IT1113070B (de) |
| LU (1) | LU79508A1 (de) |
| NL (1) | NL7804182A (de) |
| NO (1) | NO153010C (de) |
| PH (1) | PH14085A (de) |
| PT (1) | PT67868B (de) |
| SE (1) | SE430752B (de) |
| ZA (1) | ZA781832B (de) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SU826584A1 (ru) * | 1979-10-29 | 1982-11-07 | Всесоюзный государственный научно-контрольный институт ветеринарных препаратов | Вакцина против ньюкаслской болезни птиц,способ ее изготовлени и способ профилактики ньюкаслской болезни птиц |
| JPS59163313A (ja) * | 1983-03-09 | 1984-09-14 | Teijin Ltd | 経鼻投与用ペプチドホルモン類組成物 |
| US4867975A (en) * | 1988-01-27 | 1989-09-19 | University Of Delaware | Live attenuated temperature-sensitive avian infectious bronchitis virus vaccines and preparation and use thereof |
| EP0351908B1 (de) * | 1988-07-18 | 1994-10-05 | Duphar International Research B.V | Lebende Newcastle-Krankheit-Virus-Vakzine |
| US5250298A (en) * | 1988-10-07 | 1993-10-05 | University Of Delaware | Live attenuated newcastle disease virus vaccines and preparation thereof |
| US5118502A (en) * | 1989-06-20 | 1992-06-02 | The University Of Georgia Research Foundation, Inc. | Naturally attenuated newcastle disease vaccine and method of using the same |
| US5686077A (en) * | 1991-09-20 | 1997-11-11 | Akzo Nobel N.V. | Methods of immunization of poultry with vaccines against chicken anemia agent (CAA) |
| ZA927014B (en) * | 1991-09-20 | 1993-03-19 | Akzo Nv | Chicken anaemia agent vaccine. |
| EP0713397B1 (de) * | 1992-03-24 | 2002-12-11 | United Cancer Research Institute | Impfstoff enthaltend lebendes virus |
| US5427791A (en) * | 1992-08-05 | 1995-06-27 | Regents Of The University Of Minnesota | Embryonal vaccine against Newcastle disease |
| CA2181862C (en) * | 1995-08-01 | 2009-12-22 | Carla Christina Schrier | Mild newcastle disease virus vaccine |
| US6592869B2 (en) * | 1999-08-24 | 2003-07-15 | Teva Pharmaceutical Industries, Ltd. | Vaccine composition and method of using the same |
| CN100406004C (zh) | 1999-08-24 | 2008-07-30 | 特瓦制药工业有限公司 | 疫苗组合物及其制药用途 |
| RU2286765C1 (ru) * | 2005-04-14 | 2006-11-10 | Общество с ограниченной ответственностью Научно-производственное предприятие "ЭргоБио" | Иммуномодулирующее средство в форме спрея |
| KR101481164B1 (ko) * | 2008-01-30 | 2015-01-09 | 주식회사 미래셀바이오 | 체세포 유래 다능성 줄기세포의 제조 방법 |
| RU2403060C2 (ru) * | 2008-03-04 | 2010-11-10 | Владимир Олегович Виноходов | Способ профилактики болезни ньюкасла |
| US20110110975A1 (en) * | 2009-11-06 | 2011-05-12 | Streck, Inc. | Inactivated virus compositions and methods of preparing such compositions |
| US9956281B2 (en) | 2011-05-04 | 2018-05-01 | Streck, Inc. | Inactivated virus compositions and methods of preparing such compositions |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2767117A (en) * | 1953-10-22 | 1956-10-16 | Crawley John Frederick | Poultry virus vaccine products and method of preparing the same |
| US2798835A (en) * | 1954-01-18 | 1957-07-09 | American Cyanamid Co | Newcastle disease and infectious bronchitis vaccines and production thereof |
| US3548054A (en) * | 1969-06-06 | 1970-12-15 | Lilly Co Eli | Method for improving weight gains and reducing gross lesions in chickens exposed to marek's disease |
| US4053583A (en) | 1976-03-01 | 1977-10-11 | Smithkline Corporation | Live newcastle disease virus vaccines |
-
1977
- 1977-04-25 BE BE176986A patent/BE853923A/xx not_active IP Right Cessation
-
1978
- 1978-03-30 IL IL54390A patent/IL54390A/xx unknown
- 1978-03-30 ZA ZA00781832A patent/ZA781832B/xx unknown
- 1978-03-30 FR FR7809342A patent/FR2388564A1/fr active Granted
- 1978-04-04 PT PT67868A patent/PT67868B/pt unknown
- 1978-04-11 PH PH20992A patent/PH14085A/en unknown
- 1978-04-11 IT IT22203/78A patent/IT1113070B/it active
- 1978-04-11 CH CH387078A patent/CH641047A5/fr not_active IP Right Cessation
- 1978-04-12 SE SE7804116A patent/SE430752B/sv unknown
- 1978-04-12 DK DK160878A patent/DK160878A/da not_active Application Discontinuation
- 1978-04-13 CA CA301,049A patent/CA1113860A/en not_active Expired
- 1978-04-19 NL NL7804182A patent/NL7804182A/xx not_active Application Discontinuation
- 1978-04-21 FI FI781233A patent/FI59535C/fi not_active IP Right Cessation
- 1978-04-24 NO NO781421A patent/NO153010C/no unknown
- 1978-04-24 AT AT292278A patent/AT358166B/de not_active IP Right Cessation
- 1978-04-24 HU HU78RE629A patent/HU179290B/hu unknown
- 1978-04-24 US US05/899,424 patent/US4235876A/en not_active Expired - Lifetime
- 1978-04-24 DE DE19782817891 patent/DE2817891A1/de not_active Withdrawn
- 1978-04-24 IE IE811/78A patent/IE46943B1/en unknown
- 1978-04-24 LU LU79508A patent/LU79508A1/xx unknown
- 1978-04-25 AR AR271891A patent/AR218304A1/es active
- 1978-04-25 GB GB16278/78A patent/GB1593567A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| ATA292278A (de) | 1980-01-15 |
| US4235876A (en) | 1980-11-25 |
| DE2817891A1 (de) | 1978-11-09 |
| GB1593567A (en) | 1981-07-22 |
| IE46943B1 (en) | 1983-11-16 |
| PH14085A (en) | 1981-02-10 |
| NO153010B (no) | 1985-09-23 |
| NO781421L (no) | 1978-10-26 |
| LU79508A1 (fr) | 1978-09-29 |
| FR2388564B1 (de) | 1980-07-25 |
| IE780811L (en) | 1978-10-25 |
| BE853923A (fr) | 1977-10-25 |
| CA1113860A (en) | 1981-12-08 |
| NO153010C (no) | 1986-01-02 |
| DK160878A (da) | 1978-10-26 |
| IT1113070B (it) | 1986-01-20 |
| NL7804182A (nl) | 1978-10-27 |
| ZA781832B (en) | 1979-03-28 |
| FI59535B (fi) | 1981-05-29 |
| PT67868A (en) | 1978-05-01 |
| IL54390A (en) | 1980-11-30 |
| SE430752B (sv) | 1983-12-12 |
| FI781233A7 (fi) | 1978-10-26 |
| FR2388564A1 (fr) | 1978-11-24 |
| CH641047A5 (en) | 1984-02-15 |
| IL54390A0 (en) | 1978-06-15 |
| IT7822203A0 (it) | 1978-04-11 |
| HU179290B (en) | 1982-09-28 |
| SE7804116L (sv) | 1978-10-26 |
| PT67868B (en) | 1979-10-10 |
| AT358166B (de) | 1980-08-25 |
| AR218304A1 (es) | 1980-05-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM | Patent lapsed |
Owner name: SMITH KLINE - RIT |