FI59534C - Vaordmedel foer fraemjande av haorvaext och hindrande av mjaell - Google Patents
Vaordmedel foer fraemjande av haorvaext och hindrande av mjaell Download PDFInfo
- Publication number
- FI59534C FI59534C FI793410A FI793410A FI59534C FI 59534 C FI59534 C FI 59534C FI 793410 A FI793410 A FI 793410A FI 793410 A FI793410 A FI 793410A FI 59534 C FI59534 C FI 59534C
- Authority
- FI
- Finland
- Prior art keywords
- hair
- spironolactone
- och
- treatment
- vaordmedel
- Prior art date
Links
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 27
- 210000004209 hair Anatomy 0.000 description 22
- 229960002256 spironolactone Drugs 0.000 description 20
- LXMSZDCAJNLERA-ZHYRCANASA-N spironolactone Chemical compound C([C@@H]1[C@]2(C)CC[C@@H]3[C@@]4(C)CCC(=O)C=C4C[C@H]([C@@H]13)SC(=O)C)C[C@@]21CCC(=O)O1 LXMSZDCAJNLERA-ZHYRCANASA-N 0.000 description 20
- 201000004384 Alopecia Diseases 0.000 description 15
- 210000004761 scalp Anatomy 0.000 description 12
- 231100000360 alopecia Toxicity 0.000 description 9
- 230000000694 effects Effects 0.000 description 9
- 208000001840 Dandruff Diseases 0.000 description 8
- MUMGGOZAMZWBJJ-DYKIIFRCSA-N Testostosterone Chemical compound O=C1CC[C@]2(C)[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3CCC2=C1 MUMGGOZAMZWBJJ-DYKIIFRCSA-N 0.000 description 8
- 239000002904 solvent Substances 0.000 description 8
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 6
- 206010039792 Seborrhoea Diseases 0.000 description 6
- 230000003676 hair loss Effects 0.000 description 6
- 208000008742 seborrheic dermatitis Diseases 0.000 description 6
- 230000002280 anti-androgenic effect Effects 0.000 description 5
- 238000002360 preparation method Methods 0.000 description 5
- 210000003491 skin Anatomy 0.000 description 5
- 102000001307 androgen receptors Human genes 0.000 description 4
- 108010080146 androgen receptors Proteins 0.000 description 4
- 239000000203 mixture Substances 0.000 description 4
- 210000001732 sebaceous gland Anatomy 0.000 description 4
- 239000000243 solution Substances 0.000 description 4
- 229960003604 testosterone Drugs 0.000 description 4
- 229920002134 Carboxymethyl cellulose Polymers 0.000 description 3
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 3
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 3
- 229920002153 Hydroxypropyl cellulose Polymers 0.000 description 3
- 239000004098 Tetracycline Substances 0.000 description 3
- 239000000051 antiandrogen Substances 0.000 description 3
- 230000036621 balding Effects 0.000 description 3
- 239000001768 carboxy methyl cellulose Substances 0.000 description 3
- 239000008112 carboxymethyl-cellulose Substances 0.000 description 3
- 239000003795 chemical substances by application Substances 0.000 description 3
- 230000003779 hair growth Effects 0.000 description 3
- 208000024963 hair loss Diseases 0.000 description 3
- 239000001863 hydroxypropyl cellulose Substances 0.000 description 3
- 235000010977 hydroxypropyl cellulose Nutrition 0.000 description 3
- 150000003431 steroids Chemical class 0.000 description 3
- 229960002180 tetracycline Drugs 0.000 description 3
- 229930101283 tetracycline Natural products 0.000 description 3
- 235000019364 tetracycline Nutrition 0.000 description 3
- 150000003522 tetracyclines Chemical class 0.000 description 3
- 230000000699 topical effect Effects 0.000 description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 3
- 239000002202 Polyethylene glycol Substances 0.000 description 2
- RJKFOVLPORLFTN-LEKSSAKUSA-N Progesterone Chemical compound C1CC2=CC(=O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H](C(=O)C)[C@@]1(C)CC2 RJKFOVLPORLFTN-LEKSSAKUSA-N 0.000 description 2
- 239000003098 androgen Substances 0.000 description 2
- 229940030495 antiandrogen sex hormone and modulator of the genital system Drugs 0.000 description 2
- 239000001913 cellulose Substances 0.000 description 2
- 229920002678 cellulose Polymers 0.000 description 2
- 229960003843 cyproterone Drugs 0.000 description 2
- DUSHUSLJJMDGTE-ZJPMUUANSA-N cyproterone Chemical compound C1=C(Cl)C2=CC(=O)[C@@H]3C[C@@H]3[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@@](C(=O)C)(O)[C@@]1(C)CC2 DUSHUSLJJMDGTE-ZJPMUUANSA-N 0.000 description 2
- 238000009472 formulation Methods 0.000 description 2
- 210000003780 hair follicle Anatomy 0.000 description 2
- 229940088597 hormone Drugs 0.000 description 2
- 239000005556 hormone Substances 0.000 description 2
- 230000005764 inhibitory process Effects 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 210000003097 mucus Anatomy 0.000 description 2
- 229920001223 polyethylene glycol Polymers 0.000 description 2
- BDERNNFJNOPAEC-UHFFFAOYSA-N propan-1-ol Chemical compound CCCO BDERNNFJNOPAEC-UHFFFAOYSA-N 0.000 description 2
- 210000002374 sebum Anatomy 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 208000024891 symptom Diseases 0.000 description 2
- QGMIMUFFHDLVHF-WZNAKSSCSA-N (5S,8R,9S,10S,13S,14S)-10,13-dimethyl-2,4,5,6,7,8,9,11,12,14-decahydro-1H-cyclopenta[a]phenanthrene-3,17-dione Chemical compound C[C@@]12C(C=C[C@H]1[C@@H]1CC[C@H]3CC(CC[C@]3(C)[C@H]1CC2)=O)=O QGMIMUFFHDLVHF-WZNAKSSCSA-N 0.000 description 1
- NVKAWKQGWWIWPM-ABEVXSGRSA-N 17-β-hydroxy-5-α-Androstan-3-one Chemical compound C1C(=O)CC[C@]2(C)[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3CC[C@H]21 NVKAWKQGWWIWPM-ABEVXSGRSA-N 0.000 description 1
- QGXBDMJGAMFCBF-HLUDHZFRSA-N 5α-Androsterone Chemical compound C1[C@H](O)CC[C@]2(C)[C@H]3CC[C@](C)(C(CC4)=O)[C@@H]4[C@@H]3CC[C@H]21 QGXBDMJGAMFCBF-HLUDHZFRSA-N 0.000 description 1
- 235000016068 Berberis vulgaris Nutrition 0.000 description 1
- 241000335053 Beta vulgaris Species 0.000 description 1
- 241000282693 Cercopithecidae Species 0.000 description 1
- 206010013786 Dry skin Diseases 0.000 description 1
- 239000001856 Ethyl cellulose Substances 0.000 description 1
- ZZSNKZQZMQGXPY-UHFFFAOYSA-N Ethyl cellulose Chemical compound CCOCC1OC(OC)C(OCC)C(OCC)C1OC1C(O)C(O)C(OC)C(CO)O1 ZZSNKZQZMQGXPY-UHFFFAOYSA-N 0.000 description 1
- QGXBDMJGAMFCBF-UHFFFAOYSA-N Etiocholanolone Natural products C1C(O)CCC2(C)C3CCC(C)(C(CC4)=O)C4C3CCC21 QGXBDMJGAMFCBF-UHFFFAOYSA-N 0.000 description 1
- 206010049290 Feminisation acquired Diseases 0.000 description 1
- 206010019280 Heart failures Diseases 0.000 description 1
- 239000004264 Petrolatum Substances 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 102000030621 adenylate cyclase Human genes 0.000 description 1
- 108060000200 adenylate cyclase Proteins 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 229940083712 aldosterone antagonist Drugs 0.000 description 1
- 239000002170 aldosterone antagonist Substances 0.000 description 1
- 230000001548 androgenic effect Effects 0.000 description 1
- 229940030486 androgens Drugs 0.000 description 1
- 229960005471 androstenedione Drugs 0.000 description 1
- 229940061641 androsterone Drugs 0.000 description 1
- 239000003242 anti bacterial agent Substances 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 239000003899 bactericide agent Substances 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- UREBDLICKHMUKA-DVTGEIKXSA-N betamethasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@H](C)[C@@](C(=O)CO)(O)[C@@]1(C)C[C@@H]2O UREBDLICKHMUKA-DVTGEIKXSA-N 0.000 description 1
- 229960002537 betamethasone Drugs 0.000 description 1
- 230000003115 biocidal effect Effects 0.000 description 1
- 230000000903 blocking effect Effects 0.000 description 1
- 229960000978 cyproterone acetate Drugs 0.000 description 1
- UWFYSQMTEOIJJG-FDTZYFLXSA-N cyproterone acetate Chemical compound C1=C(Cl)C2=CC(=O)[C@@H]3C[C@@H]3[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@@](C(C)=O)(OC(=O)C)[C@@]1(C)CC2 UWFYSQMTEOIJJG-FDTZYFLXSA-N 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 239000002934 diuretic Substances 0.000 description 1
- 229940030606 diuretics Drugs 0.000 description 1
- 230000037336 dry skin Effects 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 239000003995 emulsifying agent Substances 0.000 description 1
- 239000000839 emulsion Substances 0.000 description 1
- 229940011871 estrogen Drugs 0.000 description 1
- 239000000262 estrogen Substances 0.000 description 1
- 229920001249 ethyl cellulose Polymers 0.000 description 1
- 235000019325 ethyl cellulose Nutrition 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 150000002191 fatty alcohols Chemical class 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 239000000499 gel Substances 0.000 description 1
- 239000003862 glucocorticoid Substances 0.000 description 1
- 239000003163 gonadal steroid hormone Substances 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 230000003054 hormonal effect Effects 0.000 description 1
- 239000003906 humectant Substances 0.000 description 1
- 239000003112 inhibitor Substances 0.000 description 1
- 208000017169 kidney disease Diseases 0.000 description 1
- 229940040145 liniment Drugs 0.000 description 1
- 239000000865 liniment Substances 0.000 description 1
- 150000002632 lipids Chemical class 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 208000019423 liver disease Diseases 0.000 description 1
- 229940041616 menthol Drugs 0.000 description 1
- FJQXCDYVZAHXNS-UHFFFAOYSA-N methadone hydrochloride Chemical compound Cl.C=1C=CC=CC=1C(CC(C)N(C)C)(C(=O)CC)C1=CC=CC=C1 FJQXCDYVZAHXNS-UHFFFAOYSA-N 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 239000012188 paraffin wax Substances 0.000 description 1
- 230000035515 penetration Effects 0.000 description 1
- 229940066842 petrolatum Drugs 0.000 description 1
- 235000019271 petrolatum Nutrition 0.000 description 1
- 239000000546 pharmaceutical excipient Substances 0.000 description 1
- 229940068918 polyethylene glycol 400 Drugs 0.000 description 1
- 239000000186 progesterone Substances 0.000 description 1
- 229960003387 progesterone Drugs 0.000 description 1
- 238000001243 protein synthesis Methods 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 239000003087 receptor blocking agent Substances 0.000 description 1
- 102000005962 receptors Human genes 0.000 description 1
- 108020003175 receptors Proteins 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 201000003779 seborrheic infantile dermatitis Diseases 0.000 description 1
- 239000013049 sediment Substances 0.000 description 1
- 230000004936 stimulating effect Effects 0.000 description 1
- 150000005846 sugar alcohols Polymers 0.000 description 1
- 230000002123 temporal effect Effects 0.000 description 1
- 230000003390 teratogenic effect Effects 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 230000014616 translation Effects 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/006—Antidandruff preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/63—Steroids; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q7/00—Preparations for affecting hair growth
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Dermatology (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Cosmetics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Steroid Compounds (AREA)
Priority Applications (12)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FI793410A FI59534C (fi) | 1979-10-31 | 1979-10-31 | Vaordmedel foer fraemjande av haorvaext och hindrande av mjaell |
| ZA00806112A ZA806112B (en) | 1979-10-31 | 1980-10-02 | Hair treatment agent promoting the growth of hair and preventing dandruff |
| IS2589A IS2589A7 (is) | 1979-10-31 | 1980-10-08 | Aðferð til framleiðslu efnis til meðferðar á auknum hárvexti og til varnar flösu. |
| GR63128A GR68425B (enExample) | 1979-10-31 | 1980-10-11 | |
| AU63515/80A AU6351580A (en) | 1979-10-31 | 1980-10-20 | Hair and scalp treatment |
| DK453680A DK453680A (da) | 1979-10-31 | 1980-10-27 | Haarbehandlingsmiddel der fremmer haarets vaekst og modvirker skael |
| AR283020A AR224783A1 (es) | 1979-10-31 | 1980-10-28 | Procedimiento para obtener una composicion para el tratamiento del cabello de uso externo que promueve el crecimiento del cabello y previene la caspa |
| DD80224813A DD153759A5 (de) | 1979-10-31 | 1980-10-29 | Haarpflegemittel zur aeusseren anwendung |
| JP15087280A JPS5697212A (en) | 1979-10-31 | 1980-10-29 | Hair treatment agent |
| PL22757980A PL227579A1 (enExample) | 1979-10-31 | 1980-10-30 | |
| NO803246A NO803246L (no) | 1979-10-31 | 1980-10-30 | Haarpleiemiddel. |
| EP80303900A EP0028525A3 (en) | 1979-10-31 | 1980-10-31 | Hair treatment agent promoting the growth of hair and preventing dandruff |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FI793410 | 1979-10-31 | ||
| FI793410A FI59534C (fi) | 1979-10-31 | 1979-10-31 | Vaordmedel foer fraemjande av haorvaext och hindrande av mjaell |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FI59534B FI59534B (fi) | 1981-05-29 |
| FI59534C true FI59534C (fi) | 1981-09-10 |
Family
ID=8513004
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI793410A FI59534C (fi) | 1979-10-31 | 1979-10-31 | Vaordmedel foer fraemjande av haorvaext och hindrande av mjaell |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP0028525A3 (enExample) |
| JP (1) | JPS5697212A (enExample) |
| AR (1) | AR224783A1 (enExample) |
| AU (1) | AU6351580A (enExample) |
| DD (1) | DD153759A5 (enExample) |
| DK (1) | DK453680A (enExample) |
| FI (1) | FI59534C (enExample) |
| GR (1) | GR68425B (enExample) |
| IS (1) | IS2589A7 (enExample) |
| NO (1) | NO803246L (enExample) |
| PL (1) | PL227579A1 (enExample) |
| ZA (1) | ZA806112B (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1194185B (it) * | 1983-04-01 | 1988-09-14 | Schiapparelli Farma | Composizione per il trattamento dell'acne |
| EP0410348A1 (en) * | 1989-07-26 | 1991-01-30 | G.D. Searle & Co. | Topical spironolactone composition |
| MX9303557A (es) * | 1992-08-06 | 1994-03-31 | Beta Pharm Co | Metodo para la administracion de un antiandrogeno, en particular, espironolactona, a traves de la piel. |
| AUPQ002999A0 (en) * | 1999-04-29 | 1999-05-20 | Soltec Research Pty Ltd | Non-aqueous shampoo composition |
| EP1154783A4 (en) * | 1999-07-06 | 2005-01-19 | Raziel Lurie | RELAXIN-CONTAINING MEDICAMENTS AND ITS USE |
| ES2224780B1 (es) * | 2002-02-21 | 2007-03-01 | Adnan Ammura Taha | Composicion regeneradora capilar. |
| US7320967B2 (en) | 2002-04-23 | 2008-01-22 | L'oreal | Cosmetic composition, method of cosmetic treatment and preparation of a composition for promoting the growth and/or preventing or delaying the loss of hair |
| US9241944B2 (en) * | 2010-06-16 | 2016-01-26 | Institut National De La Santé Et De La Recherche Médicale (Inserm) | Methods and compositions for stimulating reepithelialisation during wound healing |
| ES2984281T3 (es) | 2015-03-03 | 2024-10-29 | Richard W Yee | Composiciones que comprenden un antagonista de la aldosterona para su uso en el tratamiento de ojos secos |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3711602A (en) * | 1970-10-30 | 1973-01-16 | Crown Zellerbach Corp | Compositions for topical application for enhancing tissue penetration of physiologically active agents with dmso |
| BE788788A (fr) * | 1971-09-13 | 1973-03-13 | Treuhandvereinigung Ag | Produit pour conserver, favoriser et retablir la chevelure et procede de fabrication de ce produit |
| US3853926A (en) * | 1973-05-29 | 1974-12-10 | Searle & Co | 17{62 -hydroxy-16,16-dimethylester-4-en-3-one |
-
1979
- 1979-10-31 FI FI793410A patent/FI59534C/fi not_active IP Right Cessation
-
1980
- 1980-10-02 ZA ZA00806112A patent/ZA806112B/xx unknown
- 1980-10-08 IS IS2589A patent/IS2589A7/is unknown
- 1980-10-11 GR GR63128A patent/GR68425B/el unknown
- 1980-10-20 AU AU63515/80A patent/AU6351580A/en not_active Abandoned
- 1980-10-27 DK DK453680A patent/DK453680A/da not_active Application Discontinuation
- 1980-10-28 AR AR283020A patent/AR224783A1/es active
- 1980-10-29 DD DD80224813A patent/DD153759A5/de unknown
- 1980-10-29 JP JP15087280A patent/JPS5697212A/ja active Pending
- 1980-10-30 PL PL22757980A patent/PL227579A1/xx unknown
- 1980-10-30 NO NO803246A patent/NO803246L/no unknown
- 1980-10-31 EP EP80303900A patent/EP0028525A3/en not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| AU6351580A (en) | 1981-05-07 |
| IS2589A7 (is) | 1981-05-02 |
| EP0028525A3 (en) | 1981-10-28 |
| JPS5697212A (en) | 1981-08-05 |
| PL227579A1 (enExample) | 1981-06-19 |
| DD153759A5 (de) | 1982-02-03 |
| DK453680A (da) | 1981-05-01 |
| FI59534B (fi) | 1981-05-29 |
| EP0028525A2 (en) | 1981-05-13 |
| NO803246L (no) | 1981-05-04 |
| AR224783A1 (es) | 1982-01-15 |
| ZA806112B (en) | 1982-05-26 |
| GR68425B (enExample) | 1981-12-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM | Patent lapsed |
Owner name: ORION-YHTYMAE OY |