FI58918C - Foerfarande foer framstaellning av imidazo(2,1-a)isokinoliner och 5,6-dihydro-imidazo(2,1-a)isokinoliner med antireproduktiv aktivitet - Google Patents

Foerfarande foer framstaellning av imidazo(2,1-a)isokinoliner och 5,6-dihydro-imidazo(2,1-a)isokinoliner med antireproduktiv aktivitet Download PDF

Info

Publication number
FI58918C
FI58918C FI753045A FI753045A FI58918C FI 58918 C FI58918 C FI 58918C FI 753045 A FI753045 A FI 753045A FI 753045 A FI753045 A FI 753045A FI 58918 C FI58918 C FI 58918C
Authority
FI
Finland
Prior art keywords
formula
isoquinoline
imidazo
alkoxy
alkyl
Prior art date
Application number
FI753045A
Other languages
English (en)
Finnish (fi)
Other versions
FI753045A (da
FI58918B (fi
Inventor
Amedeo Omodei-Sale
Emilio Toia
Giulio Galliani
Leonard J Lerner
Original Assignee
Lepetit Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lepetit Spa filed Critical Lepetit Spa
Publication of FI753045A publication Critical patent/FI753045A/fi
Application granted granted Critical
Publication of FI58918B publication Critical patent/FI58918B/fi
Publication of FI58918C publication Critical patent/FI58918C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
FI753045A 1974-11-23 1975-10-31 Foerfarande foer framstaellning av imidazo(2,1-a)isokinoliner och 5,6-dihydro-imidazo(2,1-a)isokinoliner med antireproduktiv aktivitet FI58918C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB5085574 1974-11-23
GB50855/74A GB1484615A (en) 1974-11-23 1974-11-23 Tricyclic n-containing derivatives

Publications (3)

Publication Number Publication Date
FI753045A FI753045A (da) 1976-05-24
FI58918B FI58918B (fi) 1981-01-30
FI58918C true FI58918C (fi) 1981-05-11

Family

ID=10457662

Family Applications (2)

Application Number Title Priority Date Filing Date
FI753046A FI58919C (fi) 1974-11-23 1975-10-31 Foerfarande foer framstaellning av pyrazolo(5,1-a)isokinoliner och 5,6-dihydropyrazolo(5,1-a)isokinoliner med antireproduktiv aktivitet
FI753045A FI58918C (fi) 1974-11-23 1975-10-31 Foerfarande foer framstaellning av imidazo(2,1-a)isokinoliner och 5,6-dihydro-imidazo(2,1-a)isokinoliner med antireproduktiv aktivitet

Family Applications Before (1)

Application Number Title Priority Date Filing Date
FI753046A FI58919C (fi) 1974-11-23 1975-10-31 Foerfarande foer framstaellning av pyrazolo(5,1-a)isokinoliner och 5,6-dihydropyrazolo(5,1-a)isokinoliner med antireproduktiv aktivitet

Country Status (25)

Country Link
US (1) US4075342A (da)
JP (1) JPS5516513B2 (da)
AR (2) AR210476A1 (da)
AT (2) AT346332B (da)
BE (1) BE835836A (da)
CA (2) CA1068274A (da)
CH (2) CH614208A5 (da)
DD (2) DD122818A5 (da)
DE (1) DE2551868C2 (da)
DK (2) DK522275A (da)
ES (2) ES442863A1 (da)
FI (2) FI58919C (da)
FR (1) FR2291747A1 (da)
GB (1) GB1484615A (da)
GR (2) GR58292B (da)
IE (1) IE43567B1 (da)
IL (1) IL48389A (da)
IN (2) IN142014B (da)
LU (2) LU73849A1 (da)
NL (1) NL165741C (da)
NO (2) NO143577C (da)
SE (2) SE421619B (da)
SU (3) SU569290A3 (da)
YU (1) YU37328B (da)
ZA (1) ZA756792B (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4075343A (en) * 1976-09-13 1978-02-21 Pfizer Inc. Anti-allergenic 5-alkoxyimidazo[1,2-A]quinoline-2-carboxylic acids and derivatives thereof
GR70248B (da) * 1978-10-30 1982-09-01 Lepetit Spa
US4313950A (en) * 1978-10-30 1982-02-02 Gruppo Lepetit S.P.A. Antireproductive tricyclic ortho-fused nitrogen containing compounds
DE2964567D1 (en) * 1978-12-21 1983-02-24 Lepetit Spa New 3h-naphtho(1,2-d)imidazoles, processes for preparing them, compounds for use as antiinflammatory and antimicrobial agents and compositions for that use containing them
US4644002A (en) * 1979-02-09 1987-02-17 Roussel Uclaf Imidazo[2,1-C]quinolines, useful as antiallergic agents
IT1150955B (it) * 1980-06-06 1986-12-17 Lepetit Spa Derivati 3h-naft(1.2-d)-imidazolici il procedimento per la loro preparazione, il loro uso come agenti antiinfiammatori e le composizioni farmaceutiche che li contengono
DE3314843A1 (de) * 1983-04-23 1984-10-25 Beiersdorf Ag, 2000 Hamburg 1-amidino-2,3,3a,8-tetrahydro-1h-pyrazolo (5,1-a)isoindol, verfahren zu dessen herstellung, diese verbindung enthaltende zubereitungen und zwischenprodukte
GB8415540D0 (en) * 1984-06-18 1984-07-25 Fujisawa Pharmaceutical Co Imidazoisoquinoline compounds
EP0607076A1 (fr) * 1993-01-15 1994-07-20 Synthelabo Dérivés de 9h-imidazo 1,2-a benzimidazole-3-acétamide à activité GABA
WO1996025411A1 (en) * 1995-02-15 1996-08-22 Neurogen Corporation Certain bridged 4-phenyl-2-aminomethylimidazoles; new dopamine receptor subtype specific ligands
US5948912A (en) * 1995-02-15 1999-09-07 Neurogen Corporation Certain bridged 4-phenyl-2-aminomethylimidazoles; new dopamine receptor subtype specific ligands
TW416953B (en) 1996-09-25 2001-01-01 Takeda Chemical Industries Ltd Tricyclic compounds for eliciting a prostaglandin I2 receptor agonistic effect, their production and use
CN1243735C (zh) * 2001-04-19 2006-03-01 卫材株式会社 2－亚氨基吡咯烷衍生物
WO2002098863A1 (fr) * 2001-06-05 2002-12-12 Fujisawa Pharmaceutical Co., Ltd. Derive d'imidazole fondu
EP2444393A1 (en) * 2003-02-19 2012-04-25 Eisai R&D Management Co., Ltd. Methods for producing cyclic benzamidine derivatives
AU2005287170B2 (en) * 2004-09-17 2012-03-29 Exelixis, Inc Pyrazole kinase modulators and methods of use
US11142504B2 (en) 2016-03-07 2021-10-12 Northwestern University Substituted heterocycles as c-MYC targeting agents
US20170253581A1 (en) * 2016-03-07 2017-09-07 Northwestern University SUBSTITUTED HETEROCYCLES AS c-MYC TARGETING AGENTS
US11420957B2 (en) 2019-06-17 2022-08-23 Northwestern University Substituted heterocycles as c-MYC targeting agents
CN110294758B (zh) * 2019-07-06 2021-10-22 湘潭大学 2-取代5，6-二氢吡唑并[5，1-α]异喹啉、衍生物及其合成方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1244501A (en) * 1968-03-09 1971-09-02 Aspro Nicholas Ltd Heterocyclic amines
GB1347493A (en) * 1971-02-11 1974-02-27 Aspro Nicholas Ltd Benzazine derivatives

Also Published As

Publication number Publication date
NL7512848A (nl) 1976-05-25
FR2291747A1 (fr) 1976-06-18
AU8620475A (en) 1977-05-05
CH614444A5 (da) 1979-11-30
BE835836A (fr) 1976-03-16
IE43567B1 (en) 1981-04-08
SE421620B (sv) 1982-01-18
FI753045A (da) 1976-05-24
IL48389A (en) 1979-01-31
NO143578B (no) 1980-12-01
CA1068274A (en) 1979-12-18
DD122819A5 (da) 1976-11-05
YU37328B (en) 1984-08-31
GR58293B (en) 1977-09-20
ES442864A1 (es) 1977-08-16
SE7513137L (sv) 1976-05-24
NO753854L (da) 1976-05-25
ES442863A1 (es) 1977-08-16
IL48389A0 (en) 1975-12-31
SU578883A3 (ru) 1977-10-30
DK522275A (da) 1976-05-24
SU569290A3 (ru) 1977-08-15
IE43567L (en) 1976-05-23
DK522175A (da) 1976-05-24
DK152756C (da) 1988-09-26
LU73850A1 (da) 1976-06-11
JPS5516513B2 (da) 1980-05-02
CH614208A5 (da) 1979-11-15
CA1068273A (en) 1979-12-18
ZA756792B (en) 1976-10-27
FR2291747B1 (da) 1978-11-17
LU73849A1 (da) 1976-06-11
NL165741C (nl) 1981-05-15
NO753853L (da) 1976-05-25
AT344176B (de) 1978-07-10
FI58919B (fi) 1981-01-30
FI58918B (fi) 1981-01-30
GB1484615A (en) 1977-09-01
DE2551868C2 (de) 1982-07-15
AT346332B (de) 1978-11-10
DD122818A5 (da) 1976-11-05
US4075342A (en) 1978-02-21
NO143577C (no) 1981-03-11
NL165741B (nl) 1980-12-15
FI58919C (fi) 1981-05-11
FI753046A (da) 1976-05-24
IN142014B (da) 1977-05-21
NO143577B (no) 1980-12-01
DK152756B (da) 1988-05-09
YU292775A (en) 1983-04-27
NO143578C (no) 1981-03-11
DE2551868A1 (de) 1976-08-12
AR209459A1 (es) 1977-04-29
JPS5175098A (da) 1976-06-29
SE7513138L (sv) 1976-05-24
GR58292B (en) 1977-09-20
SE421619B (sv) 1982-01-18
SU582764A3 (ru) 1977-11-30
AR210476A1 (es) 1977-08-15
ATA884675A (de) 1978-03-15
ATA884575A (de) 1977-11-15
IN141710B (da) 1977-04-09

Similar Documents

Publication Publication Date Title
FI58918C (fi) Foerfarande foer framstaellning av imidazo(2,1-a)isokinoliner och 5,6-dihydro-imidazo(2,1-a)isokinoliner med antireproduktiv aktivitet
DE2711655C2 (da)
US4179560A (en) Imidazo- and pyrimido[2,1-b]quinazolines and preparation thereof
US3895113A (en) Antifertility methods employing triazoloisoquinoline derivatives
FI57105B (fi) Foerfarande foer framstaellning av nya s-triazolo(5,1-a)isoindoliner med befruktningsfoerhindrande verkan
US4309348A (en) Tricyclic indole derivatives
US4275066A (en) Antireproductive tricyclic ortho-fused nitrogen containing compounds
FI78091C (fi) Analogifoerfarande foer framstaellning av saosom dopaminoagonister anvaendbara pyrimido/4,5-g/kinolinderivat.
EP0202950B1 (en) Berban derivatives and their preparation and pharmaceutical formulation
US4020083A (en) 5-(2-Aminophenyl)-s-triazoles
Morel et al. 2-aza-1, 3-dienes with electron-releasing substituents at the 1, 3 positions. Reagents for the construction of pyridine and pyrimidine derivatives
US4313950A (en) Antireproductive tricyclic ortho-fused nitrogen containing compounds
EP0162592B1 (en) Heterocyclic amino compounds
FI80452B (fi) Foerfarande foer framstaellning av nya terapeutiskt anvaendbara triazino/6,1-a/isokinolin-5-ium-2-/1h)-id- derivat och isomerer daerav.
US4318909A (en) Benzoxazocines
US3646144A (en) Drug with hypertensive action on the base of 1-(3 4 - dimethoxy - 4-hydroxyphenyl)-2-monomethylaminoethanol
GB1561516A (en) 1-(azacylic aralkoxyphenyl) - 2 - or - 3-(bis -arylalkylamino alkanes process for their manufacture and pharmaceutical preparation containint them
US4235901A (en) 1-Hydroxyalkanamine pyrano(3,4-b)indole compositions and use thereof
US4152434A (en) Morpholine containing imidzo[4,5-b]pyridines and use thereof
US5137908A (en) 4-azahexacyclododecane compounds
WO1999006351A1 (en) Process for converting propargylic amine-n-oxides to enaminones
US3635988A (en) Racemate of 2-(4-methoxy-alpha-piperidino-benzyl)cyclohexanol
US4626522A (en) Benzoxazocines intermediates
US4122175A (en) Morpholine containing benzimidazoles
US4521423A (en) 7,8,9,10-Tetrahydrobenzo[h]quinolin-9-amine derivatives and compositions and methods for treating depression employing them

Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: GRUPPO LEPETIT S.P.A.