FI58423C - Desinfieringsmedel innehaollande ett salt av 1,6-bis-(n1-p-klorfenyldiguanido-n5)-hexan - Google Patents
Desinfieringsmedel innehaollande ett salt av 1,6-bis-(n1-p-klorfenyldiguanido-n5)-hexan Download PDFInfo
- Publication number
- FI58423C FI58423C FI1371/72A FI137172A FI58423C FI 58423 C FI58423 C FI 58423C FI 1371/72 A FI1371/72 A FI 1371/72A FI 137172 A FI137172 A FI 137172A FI 58423 C FI58423 C FI 58423C
- Authority
- FI
- Finland
- Prior art keywords
- chlorhexidine
- solution
- ppm
- hedta
- mono
- Prior art date
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- 150000003839 salts Chemical class 0.000 title description 42
- 238000000034 method Methods 0.000 title description 19
- GHXZTYHSJHQHIJ-UHFFFAOYSA-N Chlorhexidine Chemical compound C=1C=C(Cl)C=CC=1NC(N)=NC(N)=NCCCCCCN=C(N)N=C(N)NC1=CC=C(Cl)C=C1 GHXZTYHSJHQHIJ-UHFFFAOYSA-N 0.000 description 121
- 229960003260 chlorhexidine Drugs 0.000 description 115
- 239000000243 solution Substances 0.000 description 113
- URDCARMUOSMFFI-UHFFFAOYSA-N 2-[2-[bis(carboxymethyl)amino]ethyl-(2-hydroxyethyl)amino]acetic acid Chemical compound OCCN(CC(O)=O)CCN(CC(O)=O)CC(O)=O URDCARMUOSMFFI-UHFFFAOYSA-N 0.000 description 64
- 239000000203 mixture Substances 0.000 description 63
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 61
- 238000002360 preparation method Methods 0.000 description 45
- -1 alkali metal salt Chemical class 0.000 description 43
- 230000000844 anti-bacterial effect Effects 0.000 description 41
- 239000012153 distilled water Substances 0.000 description 31
- LZZYPRNAOMGNLH-UHFFFAOYSA-M Cetrimonium bromide Chemical compound [Br-].CCCCCCCCCCCCCCCC[N+](C)(C)C LZZYPRNAOMGNLH-UHFFFAOYSA-M 0.000 description 27
- 150000001875 compounds Chemical class 0.000 description 24
- 238000010790 dilution Methods 0.000 description 23
- 239000012895 dilution Substances 0.000 description 23
- RARSHUDCJQSEFJ-UHFFFAOYSA-N p-Hydroxypropiophenone Chemical compound CCC(=O)C1=CC=C(O)C=C1 RARSHUDCJQSEFJ-UHFFFAOYSA-N 0.000 description 22
- 150000003856 quaternary ammonium compounds Chemical class 0.000 description 21
- 239000002253 acid Substances 0.000 description 20
- 231100000518 lethal Toxicity 0.000 description 20
- 230000001665 lethal effect Effects 0.000 description 20
- 230000001580 bacterial effect Effects 0.000 description 19
- 229960002798 cetrimide Drugs 0.000 description 19
- KXDHJXZQYSOELW-UHFFFAOYSA-N Carbamic acid Chemical compound NC(O)=O KXDHJXZQYSOELW-UHFFFAOYSA-N 0.000 description 18
- 150000001768 cations Chemical class 0.000 description 17
- 125000001453 quaternary ammonium group Chemical group 0.000 description 17
- 238000002474 experimental method Methods 0.000 description 16
- 150000001450 anions Chemical class 0.000 description 15
- 239000000645 desinfectant Substances 0.000 description 15
- 239000002585 base Substances 0.000 description 14
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 description 13
- JTPLPDIKCDKODU-UHFFFAOYSA-N acetic acid;2-(2-aminoethylamino)ethanol Chemical compound CC(O)=O.CC(O)=O.CC(O)=O.NCCNCCO JTPLPDIKCDKODU-UHFFFAOYSA-N 0.000 description 13
- QPCDCPDFJACHGM-UHFFFAOYSA-N N,N-bis{2-[bis(carboxymethyl)amino]ethyl}glycine Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(=O)O)CCN(CC(O)=O)CC(O)=O QPCDCPDFJACHGM-UHFFFAOYSA-N 0.000 description 12
- 238000002844 melting Methods 0.000 description 12
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- 241000894006 Bacteria Species 0.000 description 11
- 239000002244 precipitate Substances 0.000 description 11
- 231100000820 toxicity test Toxicity 0.000 description 11
- 125000000217 alkyl group Chemical group 0.000 description 10
- 229940077464 ammonium ion Drugs 0.000 description 10
- 239000003899 bactericide agent Substances 0.000 description 10
- 239000008233 hard water Substances 0.000 description 10
- 239000000126 substance Substances 0.000 description 10
- 238000012360 testing method Methods 0.000 description 10
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 9
- UREZNYTWGJKWBI-UHFFFAOYSA-M benzethonium chloride Chemical compound [Cl-].C1=CC(C(C)(C)CC(C)(C)C)=CC=C1OCCOCC[N+](C)(C)CC1=CC=CC=C1 UREZNYTWGJKWBI-UHFFFAOYSA-M 0.000 description 9
- 239000007864 aqueous solution Substances 0.000 description 7
- WNBGYVXHFTYOBY-UHFFFAOYSA-N benzyl-dimethyl-tetradecylazanium Chemical class CCCCCCCCCCCCCC[N+](C)(C)CC1=CC=CC=C1 WNBGYVXHFTYOBY-UHFFFAOYSA-N 0.000 description 7
- 125000004432 carbon atom Chemical group C* 0.000 description 7
- 210000002966 serum Anatomy 0.000 description 7
- TYFSYONDMQEGJK-UHFFFAOYSA-N 2-(2,2-dihydroxyethylamino)acetic acid Chemical compound OC(O)CNCC(O)=O TYFSYONDMQEGJK-UHFFFAOYSA-N 0.000 description 6
- QGZKDVFQNNGYKY-UHFFFAOYSA-O Ammonium Chemical compound [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 description 6
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 6
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 6
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 description 6
- 239000012888 bovine serum Substances 0.000 description 6
- 238000006243 chemical reaction Methods 0.000 description 6
- 235000015097 nutrients Nutrition 0.000 description 6
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 description 5
- 229940027983 antiseptic and disinfectant quaternary ammonium compound Drugs 0.000 description 5
- 239000000460 chlorine Substances 0.000 description 5
- 229910052801 chlorine Inorganic materials 0.000 description 5
- 230000000694 effects Effects 0.000 description 5
- 229940050410 gluconate Drugs 0.000 description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-M hydroxide Chemical compound [OH-] XLYOFNOQVPJJNP-UHFFFAOYSA-M 0.000 description 5
- 230000000937 inactivator Effects 0.000 description 5
- MGFYIUFZLHCRTH-UHFFFAOYSA-N nitrilotriacetic acid Chemical compound OC(=O)CN(CC(O)=O)CC(O)=O MGFYIUFZLHCRTH-UHFFFAOYSA-N 0.000 description 5
- 238000003756 stirring Methods 0.000 description 5
- 231100000699 Bacterial toxin Toxicity 0.000 description 4
- RGHNJXZEOKUKBD-SQOUGZDYSA-M D-gluconate Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O RGHNJXZEOKUKBD-SQOUGZDYSA-M 0.000 description 4
- 230000002378 acidificating effect Effects 0.000 description 4
- 239000000908 ammonium hydroxide Substances 0.000 description 4
- 239000000688 bacterial toxin Substances 0.000 description 4
- WDRFFJWBUDTUCA-UHFFFAOYSA-N chlorhexidine acetate Chemical compound CC(O)=O.CC(O)=O.C=1C=C(Cl)C=CC=1NC(N)=NC(N)=NCCCCCCN=C(N)N=C(N)NC1=CC=C(Cl)C=C1 WDRFFJWBUDTUCA-UHFFFAOYSA-N 0.000 description 4
- 239000013078 crystal Substances 0.000 description 4
- 238000004090 dissolution Methods 0.000 description 4
- 238000010438 heat treatment Methods 0.000 description 4
- VLKZOEOYAKHREP-UHFFFAOYSA-N hexane Substances CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 description 4
- 230000002147 killing effect Effects 0.000 description 4
- 230000014759 maintenance of location Effects 0.000 description 4
- 239000006069 physical mixture Substances 0.000 description 4
- 239000007787 solid Substances 0.000 description 4
- MLRVZFYXUZQSRU-UHFFFAOYSA-N 1-chlorohexane Chemical compound CCCCCCCl MLRVZFYXUZQSRU-UHFFFAOYSA-N 0.000 description 3
- QOPUBSBYMCLLKW-UHFFFAOYSA-N 2-[2-[bis(carboxymethyl)amino]ethyl-(carboxymethyl)amino]-4-hydroxybutanoic acid Chemical compound OCCC(C(O)=O)N(CC(O)=O)CCN(CC(O)=O)CC(O)=O QOPUBSBYMCLLKW-UHFFFAOYSA-N 0.000 description 3
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 description 3
- VVZBFOKBSDGVGZ-UHFFFAOYSA-N BENZALKONIUM Chemical compound CCCCCCCCCCCCC[N+](C)(C)CC1=CC=CC=C1 VVZBFOKBSDGVGZ-UHFFFAOYSA-N 0.000 description 3
- JMHWNJGXUIJPKG-UHFFFAOYSA-N CC(=O)O[SiH](CC=C)OC(C)=O Chemical compound CC(=O)O[SiH](CC=C)OC(C)=O JMHWNJGXUIJPKG-UHFFFAOYSA-N 0.000 description 3
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 description 3
- 244000060011 Cocos nucifera Species 0.000 description 3
- 235000013162 Cocos nucifera Nutrition 0.000 description 3
- RUPBZQFQVRMKDG-UHFFFAOYSA-M Didecyldimethylammonium chloride Chemical compound [Cl-].CCCCCCCCCC[N+](C)(C)CCCCCCCCCC RUPBZQFQVRMKDG-UHFFFAOYSA-M 0.000 description 3
- 241000588724 Escherichia coli Species 0.000 description 3
- KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 description 3
- 241000589516 Pseudomonas Species 0.000 description 3
- 241000589517 Pseudomonas aeruginosa Species 0.000 description 3
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 3
- 239000000654 additive Substances 0.000 description 3
- 230000000996 additive effect Effects 0.000 description 3
- 230000015572 biosynthetic process Effects 0.000 description 3
- YMKDRGPMQRFJGP-UHFFFAOYSA-M cetylpyridinium chloride Chemical compound [Cl-].CCCCCCCCCCCCCCCC[N+]1=CC=CC=C1 YMKDRGPMQRFJGP-UHFFFAOYSA-M 0.000 description 3
- 229960001927 cetylpyridinium chloride Drugs 0.000 description 3
- RLGQACBPNDBWTB-UHFFFAOYSA-N cetyltrimethylammonium ion Chemical class CCCCCCCCCCCCCCCC[N+](C)(C)C RLGQACBPNDBWTB-UHFFFAOYSA-N 0.000 description 3
- 229960001884 chlorhexidine diacetate Drugs 0.000 description 3
- 229960004670 didecyldimethylammonium chloride Drugs 0.000 description 3
- 229940071106 ethylenediaminetetraacetate Drugs 0.000 description 3
- 229960003330 pentetic acid Drugs 0.000 description 3
- 239000000047 product Substances 0.000 description 3
- 150000003242 quaternary ammonium salts Chemical class 0.000 description 3
- 239000002904 solvent Substances 0.000 description 3
- VHUUQVKOLVNVRT-UHFFFAOYSA-N Ammonium hydroxide Chemical compound [NH4+].[OH-] VHUUQVKOLVNVRT-UHFFFAOYSA-N 0.000 description 2
- CPELXLSAUQHCOX-UHFFFAOYSA-M Bromide Chemical compound [Br-] CPELXLSAUQHCOX-UHFFFAOYSA-M 0.000 description 2
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 description 2
- WCUXLLCKKVVCTQ-UHFFFAOYSA-M Potassium chloride Chemical compound [Cl-].[K+] WCUXLLCKKVVCTQ-UHFFFAOYSA-M 0.000 description 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 2
- 101710182532 Toxin a Proteins 0.000 description 2
- 150000007513 acids Chemical class 0.000 description 2
- 150000003868 ammonium compounds Chemical class 0.000 description 2
- 229960001716 benzalkonium Drugs 0.000 description 2
- ZFFYNUGIXFSFNZ-UHFFFAOYSA-L benzyl-dimethyl-tetradecylazanium 2-[2-[bis(carboxymethyl)amino]ethyl-(carboxylatomethyl)amino]acetate Chemical compound C(CN(CC(=O)[O-])CC(=O)[O-])N(CC(=O)O)CC(=O)O.C(CCCCCCCCCCCCC)[N+](CC1=CC=CC=C1)(C)C.C(CCCCCCCCCCCCC)[N+](CC1=CC=CC=C1)(C)C ZFFYNUGIXFSFNZ-UHFFFAOYSA-L 0.000 description 2
- 150000004287 bisbiguanides Chemical class 0.000 description 2
- 239000000969 carrier Substances 0.000 description 2
- 150000001805 chlorine compounds Chemical class 0.000 description 2
- 125000001309 chloro group Chemical group Cl* 0.000 description 2
- 230000000052 comparative effect Effects 0.000 description 2
- 238000007796 conventional method Methods 0.000 description 2
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- 150000002500 ions Chemical class 0.000 description 2
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- 238000000926 separation method Methods 0.000 description 2
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- 239000003053 toxin Substances 0.000 description 2
- 231100000765 toxin Toxicity 0.000 description 2
- ILJSQTXMGCGYMG-UHFFFAOYSA-N triacetic acid Chemical compound CC(=O)CC(=O)CC(O)=O ILJSQTXMGCGYMG-UHFFFAOYSA-N 0.000 description 2
- WJMFXQBNYLYADA-UHFFFAOYSA-N 1-(3,4-dihydroxyphenyl)-6,7-dihydroxy-1,2-dihydronaphthalene-2,3-dicarboxylic acid Chemical compound C12=CC(O)=C(O)C=C2C=C(C(O)=O)C(C(=O)O)C1C1=CC=C(O)C(O)=C1 WJMFXQBNYLYADA-UHFFFAOYSA-N 0.000 description 1
- QAIGYXWRIHZZAA-UHFFFAOYSA-M 1-methylpyridin-1-ium;chloride Chemical compound [Cl-].C[N+]1=CC=CC=C1 QAIGYXWRIHZZAA-UHFFFAOYSA-M 0.000 description 1
- IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 description 1
- SEVPGNFKEDEULZ-UHFFFAOYSA-M 1-pyridin-1-ium-1-ylethanone;chloride Chemical compound [Cl-].CC(=O)[N+]1=CC=CC=C1 SEVPGNFKEDEULZ-UHFFFAOYSA-M 0.000 description 1
- RMVMTWDGTPPPIT-UHFFFAOYSA-N 2,2-dihydroxyethyl acetate Chemical compound OC(COC(C)=O)O RMVMTWDGTPPPIT-UHFFFAOYSA-N 0.000 description 1
- ZRPAUEVGEGEPFQ-UHFFFAOYSA-N 2-[4-[2-(2,3-dihydro-1H-inden-2-ylamino)pyrimidin-5-yl]pyrazol-1-yl]-1-(2,4,6,7-tetrahydrotriazolo[4,5-c]pyridin-5-yl)ethanone Chemical compound C1C(CC2=CC=CC=C12)NC1=NC=C(C=N1)C=1C=NN(C=1)CC(=O)N1CC2=C(CC1)NN=N2 ZRPAUEVGEGEPFQ-UHFFFAOYSA-N 0.000 description 1
- ZSPTYLOMNJNZNG-UHFFFAOYSA-N 3-Buten-1-ol Chemical group OCCC=C ZSPTYLOMNJNZNG-UHFFFAOYSA-N 0.000 description 1
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- ZGTMUACCHSMWAC-UHFFFAOYSA-L EDTA disodium salt (anhydrous) Chemical compound [Na+].[Na+].OC(=O)CN(CC([O-])=O)CCN(CC(O)=O)CC([O-])=O ZGTMUACCHSMWAC-UHFFFAOYSA-L 0.000 description 1
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- 101001074954 Homo sapiens Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A Proteins 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
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- LFVVNPBBFUSSHL-UHFFFAOYSA-N alexidine Chemical compound CCCCC(CC)CNC(=N)NC(=N)NCCCCCCNC(=N)NC(=N)NCC(CC)CCCC LFVVNPBBFUSSHL-UHFFFAOYSA-N 0.000 description 1
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- CADWTSSKOVRVJC-UHFFFAOYSA-N benzyl(dimethyl)azanium;chloride Chemical compound [Cl-].C[NH+](C)CC1=CC=CC=C1 CADWTSSKOVRVJC-UHFFFAOYSA-N 0.000 description 1
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- VBKJGFUJNURQMO-UHFFFAOYSA-M dodecyl-ethyl-dimethylazanium methyl sulfate Chemical compound COS([O-])(=O)=O.CCCCCCCCCCCC[N+](C)(C)CC VBKJGFUJNURQMO-UHFFFAOYSA-M 0.000 description 1
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- 238000002156 mixing Methods 0.000 description 1
- 239000012452 mother liquor Substances 0.000 description 1
- 125000001421 myristyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 150000007524 organic acids Chemical class 0.000 description 1
- 239000011368 organic material Substances 0.000 description 1
- 239000005416 organic matter Substances 0.000 description 1
- SJWPTBFNZAZFSH-UHFFFAOYSA-N pmpp Chemical compound C1CCSC2=NC=NC3=C2N=CN3CCCN2C(=O)N(C)C(=O)C1=C2 SJWPTBFNZAZFSH-UHFFFAOYSA-N 0.000 description 1
- 229910052700 potassium Inorganic materials 0.000 description 1
- 239000011591 potassium Substances 0.000 description 1
- 239000001103 potassium chloride Substances 0.000 description 1
- 235000011164 potassium chloride Nutrition 0.000 description 1
- 229940007042 proteus vulgaris Drugs 0.000 description 1
- 239000012429 reaction media Substances 0.000 description 1
- 239000012047 saturated solution Substances 0.000 description 1
- 238000007790 scraping Methods 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 159000000000 sodium salts Chemical class 0.000 description 1
- 235000020354 squash Nutrition 0.000 description 1
- 239000006228 supernatant Substances 0.000 description 1
- 210000004243 sweat Anatomy 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 239000001393 triammonium citrate Substances 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
- C07C279/24—Y being a hetero atom
- C07C279/26—X and Y being nitrogen atoms, i.e. biguanides
- C07C279/265—X and Y being nitrogen atoms, i.e. biguanides containing two or more biguanide groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE06431/71A SE370003B (enrdf_load_stackoverflow) | 1971-05-18 | 1971-05-18 | |
| SE643171 | 1971-05-18 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FI58423B FI58423B (fi) | 1980-10-31 |
| FI58423C true FI58423C (fi) | 1981-02-10 |
Family
ID=20268661
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI1371/72A FI58423C (fi) | 1971-05-18 | 1972-05-15 | Desinfieringsmedel innehaollande ett salt av 1,6-bis-(n1-p-klorfenyldiguanido-n5)-hexan |
Country Status (11)
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4051234A (en) | 1975-06-06 | 1977-09-27 | The Procter & Gamble Company | Oral compositions for plaque, caries, and calculus retardation with reduced staining tendencies |
| DE2611957C2 (de) * | 1976-03-20 | 1985-06-13 | Henkel KGaA, 4000 Düsseldorf | Antimikrobielle Mittel |
| SE425043B (sv) * | 1977-05-10 | 1982-08-30 | Kenogard Ab | Fungicid komposition, foretredesvis for anvendning som treskyddsmedel, innehallande minst en kvarter ammoniumforening i blandning med en aminkomponent |
| CA1159834A (en) * | 1979-04-26 | 1984-01-03 | Paul L. Warner, Jr. | Chlorhexidine salts and compositions of same |
| AT381001B (de) * | 1983-11-28 | 1986-08-11 | Arcana Chem Pharm | Verfahren zur herstellung klarer waesseriger desinfektionsmittelloesungen |
| DE3528209C2 (de) * | 1984-08-07 | 1993-10-28 | Fresenius Ag | Desinfektionsmittel |
| CA1302659C (en) * | 1986-10-24 | 1992-06-09 | Hans-Peter K. Gribi | Dental impression material |
| DE10052322A1 (de) * | 2000-10-21 | 2002-05-02 | Degussa | Wasserlösliche chlorhexidinhaltige Zusammensetzungen und deren Verwendung |
| DE10147186A1 (de) * | 2001-09-25 | 2003-04-24 | Beiersdorf Ag | Wirkstoffkombinationen aus Polyhexamethylenbiguanid-Hydrochlorid und Distearyldimethylammoniumchlorid und Zubereitungen, solche Wirkstoffkombinationen enthaltend |
| US20070254854A1 (en) * | 2006-05-01 | 2007-11-01 | Medi-Flex, Inc. | Aqueous Antiseptic Solution and Compatible Anionic Dye for Staining Skin |
| US20080108674A1 (en) * | 2006-05-01 | 2008-05-08 | Enturia, Inc. | Cationic antiseptic and dye formulation |
| EP2320724A2 (en) * | 2008-07-22 | 2011-05-18 | Polybiotech Limited | Sanitising compositions and methods |
| WO2019200025A1 (en) | 2018-04-11 | 2019-10-17 | New Mexico Tech University Research Park Corporation | Anti-infective formulations |
| EP3849313A1 (en) * | 2018-09-14 | 2021-07-21 | 3M Innovative Properties Company | Antimicrobial compositions comprising chlorhexidine |
| WO2024208671A1 (en) * | 2023-04-04 | 2024-10-10 | Cantel Medical (Italy) S.R.L. | Decontaminant solution and mehtod of using |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1265808A (fr) * | 1956-02-10 | 1961-07-07 | Ici Ltd | Biguanides |
| US3272863A (en) * | 1964-03-27 | 1966-09-13 | Sterling Drug Inc | 1, 1'-(alkylene) bis |
| US3468898A (en) * | 1966-05-26 | 1969-09-23 | Sterling Drug Inc | Bridged bis-biguanides and bis-guanidines |
-
1971
- 1971-05-18 SE SE06431/71A patent/SE370003B/xx unknown
-
1972
- 1972-05-12 ZA ZA723225A patent/ZA723225B/xx unknown
- 1972-05-15 FI FI1371/72A patent/FI58423C/fi active
- 1972-05-16 DE DE19722223766 patent/DE2223766A1/de not_active Ceased
- 1972-05-17 BE BE783598A patent/BE783598A/xx not_active IP Right Cessation
- 1972-05-18 FR FR7217941A patent/FR2157775B1/fr not_active Expired
- 1972-05-18 US US254440A patent/US3888947A/en not_active Expired - Lifetime
- 1972-05-18 CA CA142,666A patent/CA1003750A/en not_active Expired
- 1972-05-18 GB GB2333172A patent/GB1381361A/en not_active Expired
- 1972-05-18 NL NL7206762A patent/NL7206762A/xx active Search and Examination
- 1972-05-18 JP JP47049508A patent/JPS5911562B1/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| JPS5911562B1 (enrdf_load_stackoverflow) | 1984-03-16 |
| BE783598A (fr) | 1972-09-18 |
| CA1003750A (en) | 1977-01-18 |
| ZA723225B (en) | 1973-03-28 |
| US3888947A (en) | 1975-06-10 |
| DE2223766A1 (de) | 1972-12-14 |
| FI58423B (fi) | 1980-10-31 |
| FR2157775A1 (enrdf_load_stackoverflow) | 1973-06-08 |
| SE370003B (enrdf_load_stackoverflow) | 1974-09-30 |
| FR2157775B1 (enrdf_load_stackoverflow) | 1975-12-26 |
| NL7206762A (enrdf_load_stackoverflow) | 1972-11-21 |
| GB1381361A (en) | 1975-01-22 |
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