GB1381361A - Salts of chlorhexidine processes for their preparation and compo sitions incorporating them - Google Patents
Salts of chlorhexidine processes for their preparation and compo sitions incorporating themInfo
- Publication number
- GB1381361A GB1381361A GB2333172A GB2333172A GB1381361A GB 1381361 A GB1381361 A GB 1381361A GB 2333172 A GB2333172 A GB 2333172A GB 2333172 A GB2333172 A GB 2333172A GB 1381361 A GB1381361 A GB 1381361A
- Authority
- GB
- United Kingdom
- Prior art keywords
- chlorhexidine
- chloride
- acid
- salts
- carboxylic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000003839 salts Chemical class 0.000 title abstract 5
- GHXZTYHSJHQHIJ-UHFFFAOYSA-N Chlorhexidine Chemical class C=1C=C(Cl)C=CC=1NC(N)=NC(N)=NCCCCCCN=C(N)N=C(N)NC1=CC=C(Cl)C=C1 GHXZTYHSJHQHIJ-UHFFFAOYSA-N 0.000 title abstract 4
- 229960003260 chlorhexidine Drugs 0.000 title abstract 4
- 239000000203 mixture Substances 0.000 title abstract 3
- -1 Bis-biguanide salts Chemical class 0.000 abstract 4
- KXDHJXZQYSOELW-UHFFFAOYSA-N Carbamic acid Chemical compound NC(O)=O KXDHJXZQYSOELW-UHFFFAOYSA-N 0.000 abstract 3
- 150000003856 quaternary ammonium compounds Chemical class 0.000 abstract 2
- URDCARMUOSMFFI-UHFFFAOYSA-N 2-[2-[bis(carboxymethyl)amino]ethyl-(2-hydroxyethyl)amino]acetic acid Chemical compound OCCN(CC(O)=O)CCN(CC(O)=O)CC(O)=O URDCARMUOSMFFI-UHFFFAOYSA-N 0.000 abstract 1
- JMHWNJGXUIJPKG-UHFFFAOYSA-N CC(=O)O[SiH](CC=C)OC(C)=O Chemical compound CC(=O)O[SiH](CC=C)OC(C)=O JMHWNJGXUIJPKG-UHFFFAOYSA-N 0.000 abstract 1
- GAWIXWVDTYZWAW-UHFFFAOYSA-N C[CH]O Chemical group C[CH]O GAWIXWVDTYZWAW-UHFFFAOYSA-N 0.000 abstract 1
- LZZYPRNAOMGNLH-UHFFFAOYSA-M Cetrimonium bromide Chemical compound [Br-].CCCCCCCCCCCCCCCC[N+](C)(C)C LZZYPRNAOMGNLH-UHFFFAOYSA-M 0.000 abstract 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 abstract 1
- QPCDCPDFJACHGM-UHFFFAOYSA-N N,N-bis{2-[bis(carboxymethyl)amino]ethyl}glycine Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(=O)O)CCN(CC(O)=O)CC(O)=O QPCDCPDFJACHGM-UHFFFAOYSA-N 0.000 abstract 1
- YHGRTQVZCTXLHO-UHFFFAOYSA-M [[2,3-bis(2-methylpropyl)phenyl]-ethoxy-phenoxymethyl]-ethyl-dimethylazanium;chloride Chemical compound [Cl-].C=1C=CC(CC(C)C)=C(CC(C)C)C=1C([N+](C)(C)CC)(OCC)OC1=CC=CC=C1 YHGRTQVZCTXLHO-UHFFFAOYSA-M 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 229940027983 antiseptic and disinfectant quaternary ammonium compound Drugs 0.000 abstract 1
- 239000012736 aqueous medium Substances 0.000 abstract 1
- 229960000686 benzalkonium chloride Drugs 0.000 abstract 1
- CADWTSSKOVRVJC-UHFFFAOYSA-N benzyl(dimethyl)azanium;chloride Chemical compound [Cl-].C[NH+](C)CC1=CC=CC=C1 CADWTSSKOVRVJC-UHFFFAOYSA-N 0.000 abstract 1
- OCBHHZMJRVXXQK-UHFFFAOYSA-M benzyl-dimethyl-tetradecylazanium;chloride Chemical compound [Cl-].CCCCCCCCCCCCCC[N+](C)(C)CC1=CC=CC=C1 OCBHHZMJRVXXQK-UHFFFAOYSA-M 0.000 abstract 1
- HJMZMZRCABDKKV-UHFFFAOYSA-N carbonocyanidic acid Chemical compound OC(=O)C#N HJMZMZRCABDKKV-UHFFFAOYSA-N 0.000 abstract 1
- 150000001734 carboxylic acid salts Chemical group 0.000 abstract 1
- 125000002057 carboxymethyl group Chemical group [H]OC(=O)C([H])([H])[*] 0.000 abstract 1
- 229960001927 cetylpyridinium chloride Drugs 0.000 abstract 1
- YMKDRGPMQRFJGP-UHFFFAOYSA-M cetylpyridinium chloride Chemical compound [Cl-].CCCCCCCCCCCCCCCC[N+]1=CC=CC=C1 YMKDRGPMQRFJGP-UHFFFAOYSA-M 0.000 abstract 1
- 239000000645 desinfectant Substances 0.000 abstract 1
- OYBHBWGFMBOIMW-UHFFFAOYSA-N dodecyl(dimethyl)azanium chloride hydroxide Chemical compound [Cl-].C(CCCCCCCCCCC)[NH+](C)C.[OH-].C(CCCCCCCCCCC)[NH+](C)C OYBHBWGFMBOIMW-UHFFFAOYSA-N 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 1
- 230000014759 maintenance of location Effects 0.000 abstract 1
- 229960003330 pentetic acid Drugs 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
- C07C279/24—Y being a hetero atom
- C07C279/26—X and Y being nitrogen atoms, i.e. biguanides
- C07C279/265—X and Y being nitrogen atoms, i.e. biguanides containing two or more biguanide groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE06431/71A SE370003B (enrdf_load_stackoverflow) | 1971-05-18 | 1971-05-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1381361A true GB1381361A (en) | 1975-01-22 |
Family
ID=20268661
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB2333172A Expired GB1381361A (en) | 1971-05-18 | 1972-05-18 | Salts of chlorhexidine processes for their preparation and compo sitions incorporating them |
Country Status (11)
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4051234A (en) | 1975-06-06 | 1977-09-27 | The Procter & Gamble Company | Oral compositions for plaque, caries, and calculus retardation with reduced staining tendencies |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2611957C2 (de) * | 1976-03-20 | 1985-06-13 | Henkel KGaA, 4000 Düsseldorf | Antimikrobielle Mittel |
| SE425043B (sv) * | 1977-05-10 | 1982-08-30 | Kenogard Ab | Fungicid komposition, foretredesvis for anvendning som treskyddsmedel, innehallande minst en kvarter ammoniumforening i blandning med en aminkomponent |
| CA1159834A (en) * | 1979-04-26 | 1984-01-03 | Paul L. Warner, Jr. | Chlorhexidine salts and compositions of same |
| AT381001B (de) * | 1983-11-28 | 1986-08-11 | Arcana Chem Pharm | Verfahren zur herstellung klarer waesseriger desinfektionsmittelloesungen |
| DE3528209C2 (de) * | 1984-08-07 | 1993-10-28 | Fresenius Ag | Desinfektionsmittel |
| CA1302659C (en) * | 1986-10-24 | 1992-06-09 | Hans-Peter K. Gribi | Dental impression material |
| DE10052322A1 (de) * | 2000-10-21 | 2002-05-02 | Degussa | Wasserlösliche chlorhexidinhaltige Zusammensetzungen und deren Verwendung |
| DE10147186A1 (de) * | 2001-09-25 | 2003-04-24 | Beiersdorf Ag | Wirkstoffkombinationen aus Polyhexamethylenbiguanid-Hydrochlorid und Distearyldimethylammoniumchlorid und Zubereitungen, solche Wirkstoffkombinationen enthaltend |
| US20070254854A1 (en) * | 2006-05-01 | 2007-11-01 | Medi-Flex, Inc. | Aqueous Antiseptic Solution and Compatible Anionic Dye for Staining Skin |
| US20080108674A1 (en) * | 2006-05-01 | 2008-05-08 | Enturia, Inc. | Cationic antiseptic and dye formulation |
| CN102159072A (zh) * | 2008-07-22 | 2011-08-17 | 唐娜·K·吉尔丁 | 卫生处理组合物和方法 |
| WO2019200025A1 (en) | 2018-04-11 | 2019-10-17 | New Mexico Tech University Research Park Corporation | Anti-infective formulations |
| US20210299068A1 (en) * | 2018-09-14 | 2021-09-30 | . | Antimicrobial compositions comprising chlorhexidine |
| WO2024208671A1 (en) * | 2023-04-04 | 2024-10-10 | Cantel Medical (Italy) S.R.L. | Decontaminant solution and mehtod of using |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1265808A (fr) * | 1956-02-10 | 1961-07-07 | Ici Ltd | Biguanides |
| US3272863A (en) * | 1964-03-27 | 1966-09-13 | Sterling Drug Inc | 1, 1'-(alkylene) bis |
| US3468898A (en) * | 1966-05-26 | 1969-09-23 | Sterling Drug Inc | Bridged bis-biguanides and bis-guanidines |
-
1971
- 1971-05-18 SE SE06431/71A patent/SE370003B/xx unknown
-
1972
- 1972-05-12 ZA ZA723225A patent/ZA723225B/xx unknown
- 1972-05-15 FI FI1371/72A patent/FI58423C/fi active
- 1972-05-16 DE DE19722223766 patent/DE2223766A1/de not_active Ceased
- 1972-05-17 BE BE783598A patent/BE783598A/xx not_active IP Right Cessation
- 1972-05-18 JP JP47049508A patent/JPS5911562B1/ja active Granted
- 1972-05-18 US US254440A patent/US3888947A/en not_active Expired - Lifetime
- 1972-05-18 GB GB2333172A patent/GB1381361A/en not_active Expired
- 1972-05-18 FR FR7217941A patent/FR2157775B1/fr not_active Expired
- 1972-05-18 CA CA142,666A patent/CA1003750A/en not_active Expired
- 1972-05-18 NL NL7206762A patent/NL7206762A/xx active Search and Examination
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4051234A (en) | 1975-06-06 | 1977-09-27 | The Procter & Gamble Company | Oral compositions for plaque, caries, and calculus retardation with reduced staining tendencies |
Also Published As
| Publication number | Publication date |
|---|---|
| FI58423C (fi) | 1981-02-10 |
| US3888947A (en) | 1975-06-10 |
| JPS5911562B1 (enrdf_load_stackoverflow) | 1984-03-16 |
| ZA723225B (en) | 1973-03-28 |
| SE370003B (enrdf_load_stackoverflow) | 1974-09-30 |
| FI58423B (fi) | 1980-10-31 |
| FR2157775B1 (enrdf_load_stackoverflow) | 1975-12-26 |
| BE783598A (fr) | 1972-09-18 |
| NL7206762A (enrdf_load_stackoverflow) | 1972-11-21 |
| FR2157775A1 (enrdf_load_stackoverflow) | 1973-06-08 |
| CA1003750A (en) | 1977-01-18 |
| DE2223766A1 (de) | 1972-12-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |