FI58159C - Foerfarande foer framstaellning av tumoerfoerhindrande baumycinkomplexet och dess komponenter - Google Patents

Foerfarande foer framstaellning av tumoerfoerhindrande baumycinkomplexet och dess komponenter Download PDF

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Publication number
FI58159C
FI58159C FI771686A FI771686A FI58159C FI 58159 C FI58159 C FI 58159C FI 771686 A FI771686 A FI 771686A FI 771686 A FI771686 A FI 771686A FI 58159 C FI58159 C FI 58159C
Authority
FI
Finland
Prior art keywords
baumycin
chloroform
streptomyces
complex
methanol
Prior art date
Application number
FI771686A
Other languages
English (en)
Finnish (fi)
Other versions
FI771686A (xx
FI58159B (fi
Inventor
Hamao Umezawa
Tomio Takeuchi
Masa Hamada
Masaaki Ishizuka
Hiroshi Naganawa
Toshikazu Oki
Taiji Inui
Original Assignee
Microbial Chem Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Microbial Chem Res Found filed Critical Microbial Chem Res Found
Publication of FI771686A publication Critical patent/FI771686A/fi
Application granted granted Critical
Publication of FI58159B publication Critical patent/FI58159B/fi
Publication of FI58159C publication Critical patent/FI58159C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/56—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical directly bound to a condensed ring system having three or more carbocyclic rings, e.g. daunomycin, adriamycin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465—Streptomyces
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/886—Streptomyces

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
FI771686A 1976-05-31 1977-05-26 Foerfarande foer framstaellning av tumoerfoerhindrande baumycinkomplexet och dess komponenter FI58159C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP6381076A JPS52148064A (en) 1976-05-31 1976-05-31 Antitumors
JP6381076 1976-05-31

Publications (3)

Publication Number Publication Date
FI771686A FI771686A (xx) 1977-12-01
FI58159B FI58159B (fi) 1980-08-29
FI58159C true FI58159C (fi) 1980-12-10

Family

ID=13240090

Family Applications (1)

Application Number Title Priority Date Filing Date
FI771686A FI58159C (fi) 1976-05-31 1977-05-26 Foerfarande foer framstaellning av tumoerfoerhindrande baumycinkomplexet och dess komponenter

Country Status (19)

Country Link
US (2) US4147778A (xx)
JP (1) JPS52148064A (xx)
AU (1) AU512372B2 (xx)
BE (1) BE855098A (xx)
CA (1) CA1093998A (xx)
CH (1) CH634079A5 (xx)
DE (1) DE2724441C2 (xx)
DK (1) DK144569C (xx)
FI (1) FI58159C (xx)
FR (1) FR2353564A1 (xx)
GB (1) GB1544195A (xx)
GR (1) GR73592B (xx)
IE (1) IE45070B1 (xx)
LU (1) LU77449A1 (xx)
NL (1) NL7705812A (xx)
SE (1) SE436043B (xx)
SU (1) SU867318A3 (xx)
YU (6) YU40479B (xx)
ZA (1) ZA773228B (xx)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK160616C (da) * 1979-02-03 1991-09-02 Zaidan Hojin Biseibutsu Fremgangsmaade til fremstilling af anthracyclinderivater eller syreadditionssalte deraf
JPS5648893A (en) * 1979-09-07 1981-05-02 Sanraku Inc Preparation of anthracycline glycoside
JPS5643293A (en) * 1979-09-14 1981-04-21 Ishihara Sangyo Kaisha Ltd Novel antibiotics fa-1180 a, b, c, or their salts, and their preparation
US4439477A (en) * 1980-10-30 1984-03-27 Lignotock Verfahrenstechnik Gmbh Fiber mat for producing a three dimensional molded molding by the dry process
JPS5921394A (ja) * 1982-07-24 1984-02-03 Sanraku Inc ダウノマイシンの製造法
DK356087A (da) * 1987-07-09 1989-01-10 Biogal Gyogyszergyar Fremgangsmaade til isolering af et antibiotikum
JP2779652B2 (ja) * 1988-12-27 1998-07-23 武田薬品工業株式会社 生理活性物質ｔａｎ―１１２０，その還元体，それらの製造法および用途ならびに微生物
US4977084A (en) * 1989-02-16 1990-12-11 Board Of Trustees Operating Michigan State University Production, isolation, and identification of novel antifungal compounds
GB9727546D0 (en) * 1997-12-31 1998-03-18 Pharmacia & Upjohn Spa Anthracycline glycosides

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB846130A (en) 1956-03-23 1960-08-24 Ciba Ltd New antibiotic and derivatives and salts thereof, preparations containing the same and process for the manufacture of these substances
US3092550A (en) * 1957-10-29 1963-06-04 Ciba Geigy Corp Antibiotic danubomycin and process for its manufacture
CH362490A (de) 1957-10-29 1962-06-15 Ciba Geigy Verfahren zur Herstellung eines neuen Antibiotikums
FR1533151A (fr) 1962-05-18 1968-07-19 Rhone Poulenc Sa Nouvel antibiotique et sa préparation
US3989598A (en) * 1962-05-18 1976-11-02 Rhone-Poulenc S.A. Antibiotic daunorubicin and its preparation
US4012284A (en) * 1962-11-16 1977-03-15 Societa' Farmaceutici Italia, S.p.A. Process of preparation of antibiotic F.I. 1762 derivatives
FR1527892A (fr) * 1967-03-15 1968-06-07 Rhone Poulenc Sa Nouveau procédé de préparation de l'antibiotique 13057 r.p.
US3803124A (en) * 1968-04-12 1974-04-09 Farmaceutici It Soc Process for the preparation of adriamycin and adriamycinone and adriamycin derivatives
US3686163A (en) * 1968-05-14 1972-08-22 Farmaceutici Italia Dihydrodaunomycin antibiotic and derivatives thereof
FR1593235A (xx) 1968-11-18 1970-05-25
US3590026A (en) * 1969-01-03 1971-06-29 Phillips Petroleum Co Recovery of polymers from solution
US3864480A (en) * 1974-05-06 1975-02-04 Merck & Co Inc Cinerubin A and B As Antiparasitic Agents
US4039663A (en) * 1975-03-19 1977-08-02 Societa' Farmaceutici Italia S.P.A. Daunomycins, process for their uses and intermediates

Also Published As

Publication number Publication date
JPS52148064A (en) 1977-12-08
DK144569B (da) 1982-03-29
SE436043B (sv) 1984-11-05
YU114285A (en) 1985-10-31
DE2724441A1 (de) 1977-12-22
DE2724441C2 (de) 1985-10-17
SE7706350L (sv) 1977-12-01
FI771686A (xx) 1977-12-01
FI58159B (fi) 1980-08-29
DK144569C (da) 1982-09-13
CH634079A5 (de) 1983-01-14
GB1544195A (en) 1979-04-11
YU42641B (en) 1988-10-31
YU134277A (en) 1983-01-21
YU114385A (en) 1985-10-31
YU40479B (en) 1986-02-28
AU512372B2 (en) 1980-10-09
CA1093998A (en) 1981-01-20
BE855098A (fr) 1977-11-28
YU42642B (en) 1988-10-31
YU114585A (en) 1985-10-31
FR2353564B1 (xx) 1983-03-11
US4147778A (en) 1979-04-03
AU2541277A (en) 1978-11-30
GR73592B (xx) 1984-03-26
US4198480A (en) 1980-04-15
IE45070L (en) 1977-11-30
YU43413B (en) 1989-06-30
YU42643B (en) 1988-10-31
LU77449A1 (xx) 1977-12-14
DK233477A (da) 1977-12-01
FR2353564A1 (fr) 1977-12-30
YU43412B (en) 1989-06-30
IE45070B1 (en) 1982-06-16
ZA773228B (en) 1978-04-26
YU114685A (en) 1985-10-31
NL7705812A (nl) 1977-12-02
YU114485A (en) 1985-10-31
SU867318A3 (ru) 1981-09-23

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Owner name: ZAIDANHOJIN BISEIBUTSU KAGAKU KENKYUKAI