FI58134C - Foerfarande foer framstaellning av 1-(l-(-)-fi-amino-alfa-hydroxibutyryl)-kanamycin a - Google Patents

Foerfarande foer framstaellning av 1-(l-(-)-fi-amino-alfa-hydroxibutyryl)-kanamycin a Download PDF

Info

Publication number
FI58134C
FI58134C FI309/74A FI30974A FI58134C FI 58134 C FI58134 C FI 58134C FI 309/74 A FI309/74 A FI 309/74A FI 30974 A FI30974 A FI 30974A FI 58134 C FI58134 C FI 58134C
Authority
FI
Finland
Prior art keywords
formula
compound
kanamycin
amino
nitrobenzaldehyde
Prior art date
Application number
FI309/74A
Other languages
English (en)
Finnish (fi)
Other versions
FI58134B (fi
Inventor
Richard Henry Schreiber
John Gerard Keil
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of FI58134B publication Critical patent/FI58134B/fi
Application granted granted Critical
Publication of FI58134C publication Critical patent/FI58134C/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/46Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with hetero atoms directly attached to the ring nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/22Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/234Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00Systems containing at least three condensed rings
    • C07C2603/02Ortho- or ortho- and peri-condensed systems
    • C07C2603/04Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/22Ortho- or ortho- and peri-condensed systems containing three rings containing only six-membered rings
    • C07C2603/26Phenanthrenes; Hydrogenated phenanthrenes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FI309/74A 1973-02-07 1974-02-05 Foerfarande foer framstaellning av 1-(l-(-)-fi-amino-alfa-hydroxibutyryl)-kanamycin a FI58134C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US33037773A 1973-02-07 1973-02-07
US33037773 1973-02-07

Publications (2)

Publication Number Publication Date
FI58134B FI58134B (fi) 1980-08-29
FI58134C true FI58134C (fi) 1980-12-10

Family

ID=23289488

Family Applications (1)

Application Number Title Priority Date Filing Date
FI309/74A FI58134C (fi) 1973-02-07 1974-02-05 Foerfarande foer framstaellning av 1-(l-(-)-fi-amino-alfa-hydroxibutyryl)-kanamycin a

Country Status (10)

Country Link
JP (1) JPS575797B2 (de)
CA (1) CA1021329A (de)
CH (1) CH593994A5 (de)
DK (1) DK141910B (de)
FI (1) FI58134C (de)
HU (1) HU170378B (de)
NL (1) NL182962C (de)
SE (1) SE417971B (de)
SU (1) SU667142A3 (de)
YU (1) YU30674A (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5342038B2 (de) * 1973-11-19 1978-11-08
JPS5910360B2 (ja) * 1975-01-24 1984-03-08 萬有製薬株式会社 1−N−〔L−(一)−γ−アミノ−α−ヒドロキシブチリル〕−カナマイシン誘導体の改良された製造法
IT1139844B (it) * 1981-11-25 1986-09-24 Corvi Mora Paolo Processo per la preparazione di amikacina

Also Published As

Publication number Publication date
NL7401517A (de) 1974-08-09
JPS49102644A (de) 1974-09-27
SU667142A3 (ru) 1979-06-05
DK141910B (da) 1980-07-14
YU30674A (en) 1982-02-28
DK141910C (de) 1980-11-24
NL182962B (nl) 1988-01-18
CA1021329A (en) 1977-11-22
HU170378B (de) 1977-06-28
FI58134B (fi) 1980-08-29
CH593994A5 (en) 1977-12-30
NL182962C (nl) 1988-06-16
SE417971B (sv) 1981-04-27
JPS575797B2 (de) 1982-02-01

Similar Documents

Publication Publication Date Title
KR0149493B1 (ko) 항종양 항생물질인 ll-e33288의 n-아실 유도체와 그의 제조 방법 및 그의 사용
GB1598705A (en) 3-de-o-methylfortimicins
CN100497338C (zh) 4-甲基-7-氧-1-氮杂双环[3.2.0]庚-2-烯-2-羧酸类衍生物的制备方法
EP0328000A2 (de) Indolocarbazol-Derivate, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel
Argoudelis et al. New amino acids from Streptomyces
NZ227113A (en) Synthesis of amikacin
FI58134C (fi) Foerfarande foer framstaellning av 1-(l-(-)-fi-amino-alfa-hydroxibutyryl)-kanamycin a
CS257292B2 (en) Production method of amikacine
CH648854A5 (de) Antibiotisch wirksame aminoglykoside.
Kuroda et al. FR-900130, A NOVEL AMINO ACID ANTIBIOTIC II. ISOLATION AND STRUCTURE ELUCIDATION OF THE ACETYL DERIVATIVE OF FR-900130
US4009328A (en) Aminoglycoside 66-40C, method for its manufacture, method for its use as an intermediate in the preparation of known antibiotics and novel antibacterials
JPH0344398A (ja) 抗真菌抗生物質r106誘導体
EP0072531A1 (de) Neue Cyclophosphamid-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung
KR900001076B1 (ko) N-[4-(3-아미노프로필)아미노부틸]-2,2-디히드록시에탄아미드의 제조방법
GB1594786A (en) Fortimicin derivatives and method for production thereof
CA1046513A (en) Antibiotic derivatives
CA1285936C (en) 3-acylamino-3-deoxyallose derivatives
IGARASHI et al. TRUCTURE ELUCIDATION OF AN INTERMEDIATE OF 2-DEOXYSTREPTAMINE BIOSYNTHESIS
Burns et al. Components for tethered bilayer membranes: Synthesis of hydrophilically substituted phytanol derivatives
DE2458921B2 (de) N-(2-hydroxy-4-aminobutyryl)-derivate des antibiotikums xk-62-2, ihre salze, verfahren zu ihrer herstellung und arzneimittel
FI60217B (fi) Foerfarande foer framstaellning av 1-(l-(-)-ny-amino-alfa-hydroxibutyryl)kanamycin a
CN113773240B (zh) 吉米沙星侧链化合物的制备方法
GB1589954A (en) Everninomicin derivatives and their preparation
CN110627768A (zh) 一种莫西沙星降解杂质j的制备方法
US5637680A (en) Process for the preparation of etoposide phosphate and intermediate thereof