FI57948C - Foerfarande foer framstaellning av antiemetiska 10-(3-(4-(2-hydroxietyl)piperidino)propyl)fenotiaziner - Google Patents

Foerfarande foer framstaellning av antiemetiska 10-(3-(4-(2-hydroxietyl)piperidino)propyl)fenotiaziner Download PDF

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Publication number
FI57948C
FI57948C FI750160A FI750160A FI57948C FI 57948 C FI57948 C FI 57948C FI 750160 A FI750160 A FI 750160A FI 750160 A FI750160 A FI 750160A FI 57948 C FI57948 C FI 57948C
Authority
FI
Finland
Prior art keywords
compound
formula
propyl
piperidino
solution
Prior art date
Application number
FI750160A
Other languages
English (en)
Finnish (fi)
Other versions
FI750160A (nl
FI57948B (fi
Inventor
Jean Baget
Original Assignee
Rhone Poulenc Ind
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR7402101A external-priority patent/FR2258186A1/fr
Priority claimed from FR7437295A external-priority patent/FR2290907A2/fr
Application filed by Rhone Poulenc Ind filed Critical Rhone Poulenc Ind
Publication of FI750160A publication Critical patent/FI750160A/fi
Application granted granted Critical
Publication of FI57948B publication Critical patent/FI57948B/fi
Publication of FI57948C publication Critical patent/FI57948C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
    • C07D279/14—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
    • C07D279/18—[b, e]-condensed with two six-membered rings
    • C07D279/22—[b, e]-condensed with two six-membered rings with carbon atoms directly attached to the ring nitrogen atom
    • C07D279/24—[b, e]-condensed with two six-membered rings with carbon atoms directly attached to the ring nitrogen atom with hydrocarbon radicals, substituted by amino radicals, attached to the ring nitrogen atom
    • C07D279/28—[b, e]-condensed with two six-membered rings with carbon atoms directly attached to the ring nitrogen atom with hydrocarbon radicals, substituted by amino radicals, attached to the ring nitrogen atom with other substituents attached to the ring system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
FI750160A 1974-01-22 1975-01-22 Foerfarande foer framstaellning av antiemetiska 10-(3-(4-(2-hydroxietyl)piperidino)propyl)fenotiaziner FI57948C (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
FR7402101A FR2258186A1 (en) 1974-01-22 1974-01-22 10-((4-hydroxyethylpiperidino)alkyl)-phenothiazines - with antiemetic activity
FR7402101 1974-01-22
FR7437295A FR2290907A2 (fr) 1974-11-12 1974-11-12 Nouveaux derives de la phenothiazine, leur preparation et les compositions qui les contiennent
FR7437295 1974-11-12

Publications (3)

Publication Number Publication Date
FI750160A FI750160A (nl) 1975-07-23
FI57948B FI57948B (fi) 1980-07-31
FI57948C true FI57948C (fi) 1980-11-10

Family

ID=26218142

Family Applications (1)

Application Number Title Priority Date Filing Date
FI750160A FI57948C (fi) 1974-01-22 1975-01-22 Foerfarande foer framstaellning av antiemetiska 10-(3-(4-(2-hydroxietyl)piperidino)propyl)fenotiaziner

Country Status (21)

Country Link
US (1) US3961055A (nl)
JP (1) JPS541313B2 (nl)
AR (2) AR205635A1 (nl)
AT (1) AT338816B (nl)
AU (1) AU470810B2 (nl)
CA (1) CA1021337A (nl)
CH (2) CH602718A5 (nl)
CS (1) CS187458B2 (nl)
DE (1) DE2502504C3 (nl)
DK (1) DK17275A (nl)
ES (2) ES434026A1 (nl)
FI (1) FI57948C (nl)
GB (1) GB1460427A (nl)
HU (1) HU168855B (nl)
IE (1) IE40364B1 (nl)
IL (1) IL46484A (nl)
LU (1) LU71688A1 (nl)
NL (1) NL165739C (nl)
NO (1) NO750182L (nl)
SE (2) SE414028B (nl)
SU (1) SU577994A3 (nl)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5291879A (en) * 1976-01-23 1977-08-02 Rhone Poulenc Ind Phenothiazine derivatives
JPS55111483A (en) * 1979-02-22 1980-08-28 Eisai Co Ltd Novel phenothiazine derivative and psychotropic drug comprising it
US4666907A (en) * 1983-10-05 1987-05-19 Merck Frosst Canada, Inc. Phenothiazine and derivatives and analogs and use as leukotriene biosynthesis inhibitors
US4845083A (en) * 1983-10-05 1989-07-04 Merck Frosst Canada, Inc. Method of inhibiting mammalian leukotriene biosynthesis
EP0451675B1 (en) * 1990-04-09 1995-11-02 ZAMBON GROUP S.p.A. Process for the direct and regioselective functionalization in position 2 of phenothiazine
IT1244742B (it) * 1991-02-14 1994-08-08 Zambon Spa Processo per la funzionalizzazione diretta e regioselettiva in posizione 2 della fenotiazina

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1212031A (fr) * 1957-10-21 1960-03-21 Rhone Poulenc Sa Dérivés de la phénothiazine substitués à l'azote par une chaîne basique comportant un hétérocycle et leur préparation
FR1558912A (nl) * 1967-03-29 1969-03-07
US3879551A (en) * 1967-03-29 1975-04-22 Rhone Poulenc Sa Phenthiazine derivatives in pharmaceutical compositions

Also Published As

Publication number Publication date
CS187458B2 (en) 1979-01-31
SE414029B (sv) 1980-07-07
LU71688A1 (nl) 1975-12-09
AU470810B2 (en) 1976-04-01
IL46484A0 (en) 1975-04-25
SE7709432L (sv) 1977-08-22
JPS50123682A (nl) 1975-09-29
DE2502504B2 (de) 1979-05-10
AU7748775A (en) 1976-04-01
IE40364B1 (en) 1979-05-09
DE2502504C3 (de) 1980-01-03
IL46484A (en) 1977-11-30
AR207789A1 (es) 1976-10-29
ES434026A1 (es) 1976-12-01
SU577994A3 (ru) 1977-10-25
JPS541313B2 (nl) 1979-01-23
DE2502504A1 (de) 1975-07-24
FI750160A (nl) 1975-07-23
IE40364L (en) 1975-07-22
US3961055A (en) 1976-06-01
AT338816B (de) 1977-09-12
GB1460427A (en) 1977-01-06
DK17275A (nl) 1975-09-22
NO750182L (nl) 1975-08-18
NL165739C (nl) 1981-05-15
CH602720A5 (nl) 1978-07-31
NL7500421A (nl) 1975-07-24
ES439072A1 (es) 1977-03-01
HU168855B (nl) 1976-07-28
ATA46475A (de) 1977-01-15
CH602718A5 (nl) 1978-07-31
FI57948B (fi) 1980-07-31
CA1021337A (en) 1977-11-22
SE414028B (sv) 1980-07-07
NL165739B (nl) 1980-12-15
AR205635A1 (es) 1976-05-21
SE7500642L (nl) 1975-07-23

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