FI57398C - Foerfarande foer framstaellning av trombocyt aggregation foerhindrande (2,3-dihydroxi)propoxikinolin eller -isokinolinderivat - Google Patents

Foerfarande foer framstaellning av trombocyt aggregation foerhindrande (2,3-dihydroxi)propoxikinolin eller -isokinolinderivat Download PDF

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Publication number
FI57398C
FI57398C FI3107/74A FI310774A FI57398C FI 57398 C FI57398 C FI 57398C FI 3107/74 A FI3107/74 A FI 3107/74A FI 310774 A FI310774 A FI 310774A FI 57398 C FI57398 C FI 57398C
Authority
FI
Finland
Prior art keywords
formula
glycerol
group
optically active
give
Prior art date
Application number
FI3107/74A
Other languages
English (en)
Finnish (fi)
Other versions
FI57398B (fi
FI310774A (nl
Inventor
Kazuyuki Nakagawa
Nanami Murakami
Hideo Mori
Kaoru Tanimura
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP48120237A external-priority patent/JPS5231873B2/ja
Priority claimed from JP48120994A external-priority patent/JPS5241272B2/ja
Priority claimed from JP9098574A external-priority patent/JPS5119774A/ja
Priority claimed from JP49090986A external-priority patent/JPS5119775A/ja
Priority claimed from JP49116419A external-priority patent/JPS51125056A/ja
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Publication of FI310774A publication Critical patent/FI310774A/fi
Publication of FI57398B publication Critical patent/FI57398B/fi
Application granted granted Critical
Publication of FI57398C publication Critical patent/FI57398C/fi

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20Oxygen atoms
    • C07D215/22Oxygen atoms attached in position 2 or 4
    • C07D215/227Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/70Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
    • C07C45/71Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/753Unsaturated compounds containing a keto groups being part of a ring containing ether groups, groups, groups, or groups
    • C07C49/755Unsaturated compounds containing a keto groups being part of a ring containing ether groups, groups, groups, or groups a keto group being part of a condensed ring system with two or three rings, at least one ring being a six-membered aromatic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20Oxygen atoms
    • C07D215/24Oxygen atoms attached in position 8
    • C07D215/26Alcohols; Ethers thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/24Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D319/00Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/101,4-Dioxanes; Hydrogenated 1,4-dioxanes
    • C07D319/141,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
    • C07D319/161,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D319/18Ethylenedioxybenzenes, not substituted on the hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI3107/74A 1973-10-24 1974-10-24 Foerfarande foer framstaellning av trombocyt aggregation foerhindrande (2,3-dihydroxi)propoxikinolin eller -isokinolinderivat FI57398C (fi)

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
JP12023773 1973-10-24
JP48120237A JPS5231873B2 (nl) 1973-10-24 1973-10-24
JP48120994A JPS5241272B2 (nl) 1973-10-26 1973-10-26
JP12099473 1973-10-26
JP9098674 1974-08-07
JP9098574A JPS5119774A (ja) 1974-08-07 1974-08-07 Kogakukatsuseiojusuru shinkinaguriseroorujudotaino seizohoho
JP9098574 1974-08-07
JP49090986A JPS5119775A (en) 1974-08-07 1974-08-07 Kogakukatsuseiojusuru shinkinaguriseroorujudotaino seizohoho
JP11641974 1974-10-09
JP49116419A JPS51125056A (en) 1974-10-09 1974-10-09 A process for preparing glycerol derivatives

Publications (3)

Publication Number Publication Date
FI310774A FI310774A (nl) 1975-04-25
FI57398B FI57398B (fi) 1980-04-30
FI57398C true FI57398C (fi) 1980-08-11

Family

ID=27525510

Family Applications (1)

Application Number Title Priority Date Filing Date
FI3107/74A FI57398C (fi) 1973-10-24 1974-10-24 Foerfarande foer framstaellning av trombocyt aggregation foerhindrande (2,3-dihydroxi)propoxikinolin eller -isokinolinderivat

Country Status (10)

Country Link
US (1) US4065456A (nl)
CA (1) CA1047038A (nl)
CH (1) CH593939A5 (nl)
DE (1) DE2450658C2 (nl)
DK (1) DK147159C (nl)
FI (1) FI57398C (nl)
FR (1) FR2282869A1 (nl)
GB (1) GB1459559A (nl)
NL (1) NL179275C (nl)
SE (1) SE431451B (nl)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2651581A1 (de) * 1976-11-12 1978-05-18 Merck Patent Gmbh Chinolonderivate und verfahren zu ihrer herstellung
IE46852B1 (en) * 1977-06-10 1983-10-05 Otsuka Pharma Co Ltd Novel carbostyril derivatives
MTP848B (en) * 1978-06-27 1980-06-24 Hoechst Ag Sulfonyl ureas process for their manufacture pharmaceutical preparation on the basis of there compounds and their use
US4291050A (en) * 1979-06-21 1981-09-22 Merck & Co., Inc. 6,7-Disubstituted-2 or 2,2-substituted-5-substituted-1-indanones
US4473501A (en) * 1981-05-04 1984-09-25 G. D. Searle & Co. Dihydro azino isoquinolines
US4558130A (en) * 1984-03-27 1985-12-10 Miles Laboratories, Inc. Fluorogenic dihydroquinolone and dihydrocoumarin indicators for hydrogen peroxide
US4794079A (en) * 1984-03-27 1988-12-27 Miles Inc. Determination of hydrogen peroxide using fluorogenic dihydroquinolone and dihydrocoumarin indicators
US5177075A (en) * 1988-08-19 1993-01-05 Warner-Lambert Company Substituted dihydroisoquinolinones and related compounds as potentiators of the lethal effects of radiation and certain chemotherapeutic agents; selected compounds, analogs and process

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH67A (de) * 1889-01-08 Kapler C G W Seitliche Abführung zur Ermöglichung zweier getrennter Mahlwege vermittelst dreier Walzen
US2448767A (en) * 1942-12-05 1948-09-07 Mellon Inst Of Ind Res Process of hydroxyethylation
US3424681A (en) * 1965-11-03 1969-01-28 Nalco Chemical Co Corrosion inhibition
US3862951A (en) * 1971-09-02 1975-01-28 Syva Co 2{40 Quinoldinyl glycerol compounds
DE2331223C2 (de) * 1972-06-19 1984-11-22 Kohjin Co., Ltd., Tokio / Tokyo S-substituierte-2-Thioadenosine, deren 5'-Monophosphate, Verfahren zu deren Herstellung und Arzneimittel, welche diese enthalten

Also Published As

Publication number Publication date
FR2282869B1 (nl) 1978-07-21
DK558774A (nl) 1975-07-07
DK147159B (da) 1984-04-30
US4065456A (en) 1977-12-27
FI57398B (fi) 1980-04-30
SE431451B (sv) 1984-02-06
GB1459559A (en) 1976-12-22
NL7413858A (nl) 1975-04-28
DK147159C (da) 1984-10-29
DE2450658C2 (de) 1985-03-21
FR2282869A1 (fr) 1976-03-26
NL179275C (nl) 1986-08-18
SE7413358L (nl) 1975-04-25
DE2450658A1 (de) 1975-05-07
NL179275B (nl) 1986-03-17
CH593939A5 (nl) 1977-12-30
FI310774A (nl) 1975-04-25
CA1047038A (en) 1979-01-23

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