FI57256C - Foerfarande foer framstaellning av terapeutiskt anvaendbara 1-laegre-alkyl-2-cyano-2,3-dihydro-1h-1,4-bensodiazepinderivat - Google Patents

Foerfarande foer framstaellning av terapeutiskt anvaendbara 1-laegre-alkyl-2-cyano-2,3-dihydro-1h-1,4-bensodiazepinderivat Download PDF

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Publication number
FI57256C
FI57256C FI2240/74A FI224074A FI57256C FI 57256 C FI57256 C FI 57256C FI 2240/74 A FI2240/74 A FI 2240/74A FI 224074 A FI224074 A FI 224074A FI 57256 C FI57256 C FI 57256C
Authority
FI
Finland
Prior art keywords
cyano
dihydro
benzodiazepine
formula
methyl
Prior art date
Application number
FI2240/74A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI57256B (fi
FI224074A (xx
Inventor
Robert Ye-Fong Ning
Morton A Schwartz
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of FI224074A publication Critical patent/FI224074A/fi
Publication of FI57256B publication Critical patent/FI57256B/fi
Application granted granted Critical
Publication of FI57256C publication Critical patent/FI57256C/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
FI2240/74A 1973-07-27 1974-07-23 Foerfarande foer framstaellning av terapeutiskt anvaendbara 1-laegre-alkyl-2-cyano-2,3-dihydro-1h-1,4-bensodiazepinderivat FI57256C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US383228A US3925358A (en) 1973-07-27 1973-07-27 1-Lower alkyl-2-substituted-1,4-benzodiazepines
US38322873 1973-07-27

Publications (3)

Publication Number Publication Date
FI224074A FI224074A (xx) 1975-01-28
FI57256B FI57256B (fi) 1980-03-31
FI57256C true FI57256C (fi) 1980-07-10

Family

ID=23512244

Family Applications (1)

Application Number Title Priority Date Filing Date
FI2240/74A FI57256C (fi) 1973-07-27 1974-07-23 Foerfarande foer framstaellning av terapeutiskt anvaendbara 1-laegre-alkyl-2-cyano-2,3-dihydro-1h-1,4-bensodiazepinderivat

Country Status (24)

Country Link
US (1) US3925358A (xx)
JP (1) JPS5041884A (xx)
AR (1) AR210987A1 (xx)
AT (1) AT340430B (xx)
BE (1) BE818132A (xx)
CA (1) CA1024512A (xx)
CH (1) CH602673A5 (xx)
DD (1) DD116038A5 (xx)
DE (1) DE2436147A1 (xx)
DK (1) DK138320B (xx)
ES (1) ES428597A1 (xx)
FI (1) FI57256C (xx)
FR (1) FR2238498B1 (xx)
GB (1) GB1407585A (xx)
HU (1) HU169331B (xx)
IE (1) IE39631B1 (xx)
IL (1) IL45102A (xx)
LU (1) LU70603A1 (xx)
NL (1) NL7410101A (xx)
NO (1) NO137692C (xx)
PH (1) PH11991A (xx)
PL (1) PL89890B1 (xx)
SE (1) SE419445B (xx)
ZA (1) ZA743857B (xx)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE13884T1 (de) * 1979-12-24 1985-07-15 Kali Chemie Pharma Gmbh 2-azidomethyl-1,4-benzodiazepine und deren salze sowie verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel.
DE2952279A1 (de) 1979-12-24 1981-06-25 Kali-Chemie Pharma Gmbh, 3000 Hannover Neue 2-acylaminomethyl-1,4-benzodiazepine und deren salze sowie verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3048264A1 (de) * 1980-12-20 1982-09-09 Kali-Chemie Pharma Gmbh, 3000 Hannover 2-acylaminomethyl-1,4-benzodiazepine und deren salze sowie verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3124013A1 (de) * 1981-06-19 1982-12-30 Kali-Chemie Pharma Gmbh, 3000 Hannover 2-acylaminomethyl-1,4-benzodiazepin-verbindungen sowie verfahren und zwischenprodukte zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3481921A (en) * 1965-10-22 1969-12-02 Hoffmann La Roche Benzodiazepines

Also Published As

Publication number Publication date
CA1024512A (en) 1978-01-17
DK138320C (xx) 1979-01-22
FR2238498B1 (xx) 1977-07-08
DE2436147A1 (de) 1975-02-13
LU70603A1 (xx) 1976-06-11
SE7409734L (xx) 1975-01-28
BE818132A (fr) 1975-01-27
AU7169774A (en) 1976-01-29
AT340430B (de) 1977-12-12
GB1407585A (en) 1975-09-24
FI57256B (fi) 1980-03-31
IE39631L (en) 1975-01-27
SE419445B (sv) 1981-08-03
NO137692C (no) 1978-04-05
ES428597A1 (es) 1976-08-16
IL45102A0 (en) 1974-09-10
DK402774A (xx) 1975-04-01
HU169331B (xx) 1976-11-28
ZA743857B (en) 1975-06-25
ATA617074A (de) 1977-04-15
US3925358A (en) 1975-12-09
DD116038A5 (xx) 1975-11-05
PH11991A (en) 1978-10-05
JPS5041884A (xx) 1975-04-16
DK138320B (da) 1978-08-14
PL89890B1 (xx) 1976-12-31
NO137692B (no) 1977-12-27
FI224074A (xx) 1975-01-28
CH602673A5 (xx) 1978-07-31
IL45102A (en) 1978-01-31
NO742738L (xx) 1975-02-24
IE39631B1 (en) 1978-11-22
AR210987A1 (es) 1977-10-14
NL7410101A (nl) 1975-01-29
FR2238498A1 (xx) 1975-02-21

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