FI56969C - Foerfarande foer separering av en eller flera steroler eller en blandning av steroler - Google Patents

Foerfarande foer separering av en eller flera steroler eller en blandning av steroler Download PDF

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Publication number
FI56969C
FI56969C FI772064A FI772064A FI56969C FI 56969 C FI56969 C FI 56969C FI 772064 A FI772064 A FI 772064A FI 772064 A FI772064 A FI 772064A FI 56969 C FI56969 C FI 56969C
Authority
FI
Finland
Prior art keywords
weight
sterols
methanol
separated
acetone
Prior art date
Application number
FI772064A
Other languages
English (en)
Finnish (fi)
Other versions
FI772064A (sv
FI56969B (fi
Inventor
Aoke Allan Johansson
Riitta Helena Kristii Kivikari
Elias Uolevi Suokas
Original Assignee
Kaukas Ab Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kaukas Ab Oy filed Critical Kaukas Ab Oy
Publication of FI772064A publication Critical patent/FI772064A/fi
Application granted granted Critical
Publication of FI56969B publication Critical patent/FI56969B/fi
Publication of FI56969C publication Critical patent/FI56969C/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)

Claims (5)

1. Förfarande för avksiljning av en eller flera steroler eller en blandning av steroler, selektivt och med gott utbyte, frän en oförtvälbar, möjligen rikligt med betulin innehällande fraktion av ra sulfatsäpa, förtvälade vegetabiliska oljor eller tallolja, kännetecknat därav, att den sterolhaltiga oförtvälbara fraktionen upplöses i en vattenolöslig blandning av lösningsmedel, vars samman-sättning är 30 - 95 vikt-/£ hexan, 5-50 vikt-# aceton, och O-50 vikt-#, lämpligen 3 - 10 vikt-#, metanol, varefter ur den erhällna lösningen extraheras de polära ämnena, sterolerna inbe-räknade, med en blandning omfattande 30 - 99,9 vikt-#, lämpligen 35 - 50 vikt-#, metanol, 20 - 50 vikt-#, lämpligen 25 - 39 vikt-#, hexan, 10 - 5J0 vikt-$, lämpligen 15~25 vikt-$, aceton, och 0,1 - 10 vikt-#, lämpligen 0,5 - 3 vikt-#, vatten, samt högst 10 vikt-#, lämpligen 5-10 vikt-5#, andra oförtvälbara ämnen än steroler, t.ex. betulin, varefter den hydrofila fasen separeras och koncentreras genom avdunstning, och sterolerna eller sterolen utkristalliseras genom nedkylning, samt avskiljes.
2. Förfarande enligt patentkravet 1,kännetecknat därav, att den hydrofoba lösningsmedelsblandningen bestär av 60 - 85 vikt-J» hexan, 5-3Ο vikt->? aceton, och 3 _ 10 vikt-/2 metanol, och den hydrofila lösningsmedelsblandningen av 35 “ 50 vikt-# metanol, 25 - 35 vikt-ϊ hexan, 15-25 vikt-# aceton, och 0,5-3 vikt-J» vatten, samt 5-10 vikt-J? andra oförtvälbara ämnen än steroler.
3». Kontinuerligt förfarande enligt patentkraven 1 och 2,k8nneteck~ n a t därav, att den hydrofila lösningsmedelsblandningen utgöres av det hydrofila kondensat, som erhälles vid koncentrering av den separerade hydrofila fasen samt den vid kristalliseringssteget erhällna moderluten, och den hydrofoba lösnings-medelsblandningen utgöres av den erhällna hydrofoba fasen.
FI772064A 1976-07-02 1977-07-01 Foerfarande foer separering av en eller flera steroler eller en blandning av steroler FI56969C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US70211876 1976-07-02
US05/702,118 US4044031A (en) 1976-07-02 1976-07-02 Process for the separation of sterols

Publications (3)

Publication Number Publication Date
FI772064A FI772064A (sv) 1978-01-03
FI56969B FI56969B (fi) 1980-01-31
FI56969C true FI56969C (fi) 1980-05-12

Family

ID=24819935

Family Applications (1)

Application Number Title Priority Date Filing Date
FI772064A FI56969C (fi) 1976-07-02 1977-07-01 Foerfarande foer separering av en eller flera steroler eller en blandning av steroler

Country Status (8)

Country Link
US (1) US4044031A (sv)
JP (1) JPS5325600A (sv)
CA (1) CA1065303A (sv)
DD (1) DD131471A5 (sv)
DE (1) DE2729868C2 (sv)
FI (1) FI56969C (sv)
FR (1) FR2356669A1 (sv)
SE (1) SE437269B (sv)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI57270C (fi) * 1977-02-16 1980-07-10 Vaeinoe Erae Foerfarande foer framstaellning av laempliga polyuretanbelaeggningar foer metallplaot ur neutralaemnen av blandsaopa
US4153622A (en) * 1978-05-18 1979-05-08 Medipolar Oy Process for the recovery of β-sitosterol
FI58333C (fi) * 1978-10-27 1981-01-12 Kaukas Ab Oy Foerfarande foer framstaellning av under 5 vikt-% alfa2-sitosterol innehaollande beta-sitosterolkoncentrat
FI59416C (fi) * 1979-11-19 1981-08-10 Farmos Oy Foerfarande foer utvinning av beta-sitosterol ur en sterolblandning utvunnen fraon raosaopans neutralfraktion
FI65440C (fi) * 1981-07-21 1984-05-10 Kaukas Ab Oy Foerfarande foer separering av beta-sitosterol med en laog alfa-sitosterolhalt
FI812279L (fi) * 1981-07-21 1983-01-22 Kaukas Ab Oy Foerfarande foer rening av -sitosterol isolerad fraon neutralaemnet av sulfatcellulosaprocessens raosaopa
JPS5951912A (ja) * 1982-09-17 1984-03-26 Matsushita Electric Ind Co Ltd ベンゼン誘導体重合体
US5117016A (en) * 1991-05-13 1992-05-26 Eastman Kodak Company Method for obtaining a stigmasterol enriched product from deodorizer distillate
EP0783514B2 (en) * 1994-09-29 2007-08-01 The University Of British Columbia Sterol compositions from pulping soap
WO2000004038A1 (en) * 1998-07-14 2000-01-27 Westvaco Corporation Isolation and purification of sterols from neutrals fraction of tall oil pitch by direct precipitation
AU4958799A (en) * 1998-07-14 2000-02-07 Westvaco Corporation Isolation and purification of sterols from neutrals fraction of tall oil pitch by single decantation precipitation
AU4958699A (en) * 1998-08-17 2000-03-06 Westvaco Corporation Isolation and purification of sterols from neutrals fraction of tall oil pitch by direct crystallization, single phase
AU4958399A (en) * 1998-08-27 2000-03-21 Westvaco Corporation Isolation and purification of sterols from neutrals fraction of tall oil pitch by direct crystallization, dual phase
US6107456A (en) * 1998-08-31 2000-08-22 Arizona Chemical Corporation Method for separating sterols from tall oil
US6057462A (en) * 1998-11-06 2000-05-02 Westvaco Corporation Isolation and purification of sterols from neutrals fraction of tall oil pitch by single decantation crystallization
AU4958599A (en) * 1998-12-07 2000-06-26 Westvaco Corporation Isolation and purification of sterols from neutrals fraction of tall oil pitch by dual decantation crystallization
WO2000064923A1 (en) * 1999-04-27 2000-11-02 Sterol Technologies Ltd. Process for the isolation of phytosterols from neutral substances using hydrocarbon and alcohol based solvent systems
WO2000064921A2 (en) * 1999-04-27 2000-11-02 Forbes Medi-Tech Inc. Process of purifying phytosterols from wood or plant-derived sources by means of metal salt complexes and compositions resulting therefrom
DE50102055D1 (de) * 2000-03-28 2004-05-27 Birken Gmbh Emulsion enthaltend einen triterpen-haltigen pflanzenextrakt, verfahren zur herstellung der emulsion sowie zur gewinnung des pflanzenextraktes
KR100434517B1 (ko) * 2002-04-26 2004-06-05 주식회사 신동방 고순도 스테롤의 제조방법
CA2433246A1 (en) * 2003-06-25 2004-12-25 Telum Technologies Inc. Process for recovering value-added products from pulping soap
WO2007054759A1 (en) * 2005-11-08 2007-05-18 Council Of Scientific And Industrial Research A process for the preparation of high purity phytosterols from deodourizer distillate from vegetable oils
JP4914113B2 (ja) * 2006-05-11 2012-04-11 ハリマ化成株式会社 ステロール類の製造方法
US20080015367A1 (en) * 2006-07-11 2008-01-17 Wiley Organics, Inc. Process for isolating phytosterols and tocopherols from deodorizer distillate
US8318962B2 (en) * 2006-12-29 2012-11-27 Cognis Ip Management Gmbh Process for recovering sterols from a crude source containing sterol esters
SE540791C2 (sv) 2016-01-29 2018-11-13 Stora Enso Oyj Extraction of phytosterols
WO2017137908A1 (en) 2016-02-12 2017-08-17 Stora Enso Oyj Distillation of neutral compounds from tall oil soap
US11912874B2 (en) 2016-06-10 2024-02-27 A.L.M. Holding Company Crude sterol as an additive in asphalt binder
AU2017311203B2 (en) 2016-08-09 2021-11-04 A.L.M Holding Company Sterol blends as an additive in asphalt binder
AU2018215360B2 (en) 2017-02-02 2023-07-27 A.L.M Holding Company Bituminous emulsions containing sterol additive for asphalt pavement
US11427697B2 (en) 2017-07-26 2022-08-30 A.L.M. Holding Company Use of sterols from animal waste as an additive in asphalt binder
RU2655444C1 (ru) * 2017-09-11 2018-05-29 Акционерное общество "Управляющая компания "Биохимического холдинга "Оргхим" Способ выделения фитостеринов из таллового пека
EP3697849A1 (en) 2017-10-20 2020-08-26 A.L.M. Holding Company Asphalt emulsion surface treatment containing sterol
IL275631B1 (en) 2018-01-04 2024-06-01 Amryt Res Limited Birch bark extracts containing betulin and their formulation

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2530809A (en) * 1949-08-23 1950-11-21 Pittsburgh Plate Glass Co Fractionation of tall oil
US2843610A (en) * 1957-08-28 1958-07-15 Eastman Kodak Co Separation of sterols from deodorizer sludges
US2963494A (en) * 1957-12-16 1960-12-06 Upjohn Co Purification of sterols
US3335154A (en) * 1963-06-04 1967-08-08 Eastman Kodak Co Separation of tocopherols and sterols from deodorizer sludge and the like
US3840570A (en) * 1970-12-07 1974-10-08 Procter & Gamble Process for preparing sterols from tall oil pitch

Also Published As

Publication number Publication date
FR2356669A1 (fr) 1978-01-27
JPS633878B2 (sv) 1988-01-26
US4044031A (en) 1977-08-23
FR2356669B1 (sv) 1982-05-28
FI772064A (sv) 1978-01-03
DE2729868C2 (de) 1985-11-28
SE7707461L (sv) 1978-01-03
DD131471A5 (de) 1978-06-28
JPS5325600A (en) 1978-03-09
FI56969B (fi) 1980-01-31
DE2729868A1 (de) 1978-01-12
CA1065303A (en) 1979-10-30
SE437269B (sv) 1985-02-18

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Owner name: OY KAUKAS AB