FI55843C - Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 9,10-dihydro-9- eller -10-hydroxi-imino-4-(1-alkyl-4-piperidyliden)-4h-benso(4,5)cyklohepta(1,2-b)tiofenderivat och deras syraadditionssalter - Google Patents

Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 9,10-dihydro-9- eller -10-hydroxi-imino-4-(1-alkyl-4-piperidyliden)-4h-benso(4,5)cyklohepta(1,2-b)tiofenderivat och deras syraadditionssalter

Info

Publication number
FI55843C
FI55843C FI110/73A FI11073A FI55843C FI 55843 C FI55843 C FI 55843C FI 110/73 A FI110/73 A FI 110/73A FI 11073 A FI11073 A FI 11073A FI 55843 C FI55843 C FI 55843C
Authority
FI
Finland
Prior art keywords
tiofenderivat
piperidylidene
eller
cyclohepta
imino
Prior art date
Application number
FI110/73A
Other languages
English (en)
Finnish (fi)
Other versions
FI55843B (fi
Inventor
Jean-Pierre Bourquin
Gustav Schwarb
Erwin Waldvogel
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH99072A external-priority patent/CH569006A5/de
Priority claimed from CH99272A external-priority patent/CH562244A5/de
Priority claimed from CH98672A external-priority patent/CH569012A5/de
Priority claimed from CH98872A external-priority patent/CH565172A5/de
Application filed by Sandoz Ag filed Critical Sandoz Ag
Priority to FI790145A priority Critical patent/FI59591C/fi
Publication of FI55843B publication Critical patent/FI55843B/fi
Application granted granted Critical
Publication of FI55843C publication Critical patent/FI55843C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/08—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing alicyclic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Neurosurgery (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FI110/73A 1972-01-24 1973-01-16 Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 9,10-dihydro-9- eller -10-hydroxi-imino-4-(1-alkyl-4-piperidyliden)-4h-benso(4,5)cyklohepta(1,2-b)tiofenderivat och deras syraadditionssalter FI55843C (fi)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FI790145A FI59591C (fi) 1972-01-24 1979-01-17 Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 4h-benso(4,5)syklohepta(1,2-b)tiofen-derivat

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CH99072A CH569006A5 (en) 1972-01-24 1972-01-24 4-piperidylidene benzocycloheptathiophenes - - antihistamines and serotonin and acetyl choline inhibitors
CH99272A CH562244A5 (en) 1972-01-24 1972-01-24 4-piperidylidene benzocycloheptathiophenes - - antihistamines and serotonin and acetyl choline inhibitors
CH98672A CH569012A5 (en) 1972-01-24 1972-01-24 4-piperidylidene benzocycloheptathiophenes - - antihistamines and serotonin and acetyl choline inhibitors
CH98872A CH565172A5 (en) 1972-01-24 1972-01-24 4-piperidylidene benzocycloheptathiophenes - - antihistamines and serotonin and acetyl choline inhibitors

Publications (2)

Publication Number Publication Date
FI55843B FI55843B (fi) 1979-06-29
FI55843C true FI55843C (fi) 1979-10-10

Family

ID=27428052

Family Applications (1)

Application Number Title Priority Date Filing Date
FI110/73A FI55843C (fi) 1972-01-24 1973-01-16 Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 9,10-dihydro-9- eller -10-hydroxi-imino-4-(1-alkyl-4-piperidyliden)-4h-benso(4,5)cyklohepta(1,2-b)tiofenderivat och deras syraadditionssalter

Country Status (14)

Country Link
US (1) US3862156A (en:Method)
JP (1) JPS5760351B2 (en:Method)
BE (1) BE794377A (en:Method)
CY (1) CY992A (en:Method)
DD (1) DD102701A5 (en:Method)
DE (1) DE2302944C2 (en:Method)
FI (1) FI55843C (en:Method)
FR (1) FR2183663B2 (en:Method)
GB (1) GB1415591A (en:Method)
HK (1) HK11279A (en:Method)
HU (1) HU165130B (en:Method)
MY (1) MY7900114A (en:Method)
NL (1) NL7300796A (en:Method)
SE (1) SE383347B (en:Method)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI761607A7 (en:Method) * 1975-06-16 1976-12-17 Sandoz Ag
GB1570500A (en) * 1976-01-02 1980-07-02 Sandoz Ltd Anti-9,10-dihydro-4-(1-methyl-4-piperidylidene)-4h-benzo(4,5) cyclohepta (1,2-b)thiophen-10(9h)-one oxime
US4132796A (en) * 1977-12-01 1979-01-02 Merck & Co., Inc. Antipsychotic 3-trifluoromethylsulfinyl analogs of cyproheptadine
US4356184A (en) * 1980-06-04 1982-10-26 G. D. Searle & Co. Anti-allergic or antihypertensive 1-piperidinylmethyl benzenamines
US4355036A (en) * 1980-06-19 1982-10-19 Schering Corporation Tricyclic-substituted piperidine antihistamines
RU2266115C2 (ru) * 1999-09-13 2005-12-20 Бридж Фарма, Инк. Оптически активные изомеры кетотифена и их терапевтически активные метаболиты
ATE516804T1 (de) * 1999-09-13 2011-08-15 Bridge Pharma Inc Optisch aktive isomere von ketotifen und deren therapeutisch wirksame metabolite
MX2010008400A (es) 2008-01-30 2010-08-23 Nippon Zoki Pharmaceutical Co Derivado de piperidina.
EP2727919B1 (en) * 2011-06-28 2019-05-08 Fujian Mindong Rejuvenation Pharmaceutical Co., Ltd. Benzocycloheptanethiophene derivatives for anti-allergic reactions
CN104045633B (zh) * 2014-06-26 2017-07-21 福建省闽东力捷迅药业有限公司 一种富马酸卢帕替芬晶型a及其制备方法
CN104031035B (zh) * 2014-06-26 2017-08-25 福建省闽东力捷迅药业有限公司 一种富马酸卢帕替芬混晶及其制备方法
CN113880801A (zh) * 2020-07-03 2022-01-04 合肥医工医药股份有限公司 一类三环化合物、其制备方法及其医药用途

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL297097A (en:Method) * 1962-08-31
US3491103A (en) * 1963-12-19 1970-01-20 Sandoz Ag Certain 4h-benzo(4,5)cyclohepta-(1,2-b) thiophenes
US3466291A (en) * 1966-02-16 1969-09-09 Sandoz Ag 4(2-dialkylaminoethoxy or 2-piperidinoethoxy) - 9,10 - dihydro benzo(4,5)cyclohepta(1,2-b)thiophene derivatives
CH504466A (de) * 1969-02-07 1971-03-15 Sandoz Ag Verfahren zur Herstellung von 4-(1-Methyl-4-piperidyliden-N-oxid)- -9,10-dihydro-4H-benzo(4,5)cycloheptal(1,2-b)thiophen
CH531000A (de) * 1970-03-11 1972-11-30 Sandoz Ag Verfahren zur Herstellung neuer Benzocycloheptathiophene

Also Published As

Publication number Publication date
DD102701A5 (en:Method) 1973-12-20
US3862156A (en) 1975-01-21
BE794377A (fr) 1973-07-23
MY7900114A (en) 1979-12-31
FR2183663A2 (en:Method) 1973-12-21
GB1415591A (en) 1975-11-26
DE2302944A1 (de) 1973-08-02
HK11279A (en) 1979-03-16
CY992A (en) 1979-08-02
HU165130B (en:Method) 1974-06-28
SE383347B (sv) 1976-03-08
JPS4885575A (en:Method) 1973-11-13
FI55843B (fi) 1979-06-29
JPS5760351B2 (en:Method) 1982-12-18
DE2302944C2 (de) 1982-11-25
NL7300796A (en:Method) 1973-07-26
FR2183663B2 (en:Method) 1976-07-02

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