SE432767B - Forfarande for framstellning av oxazolo-(5,4-b)-pyridiner - Google Patents
Forfarande for framstellning av oxazolo-(5,4-b)-pyridinerInfo
- Publication number
- SE432767B SE432767B SE7604385A SE7604385A SE432767B SE 432767 B SE432767 B SE 432767B SE 7604385 A SE7604385 A SE 7604385A SE 7604385 A SE7604385 A SE 7604385A SE 432767 B SE432767 B SE 432767B
- Authority
- SE
- Sweden
- Prior art keywords
- oxazolo
- pyridines
- procedure
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/69—Two or more oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/61—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
- C07D213/80—Acids; Esters in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pain & Pain Management (AREA)
- Public Health (AREA)
- Rheumatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US26289872A | 1972-06-14 | 1972-06-14 | |
BE147896A BE819177R (fr) | 1972-06-14 | 1974-08-26 | Oxazolo- et thiazolopyridines |
Publications (2)
Publication Number | Publication Date |
---|---|
SE7604385L SE7604385L (sv) | 1976-04-14 |
SE432767B true SE432767B (sv) | 1984-04-16 |
Family
ID=25648082
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE7307412A SE401675B (sv) | 1972-06-14 | 1973-05-25 | Sett att framstella 1,3-oxazolo/4,5-b/pyridinderivat |
SE7604385A SE432767B (sv) | 1972-06-14 | 1976-04-14 | Forfarande for framstellning av oxazolo-(5,4-b)-pyridiner |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE7307412A SE401675B (sv) | 1972-06-14 | 1973-05-25 | Sett att framstella 1,3-oxazolo/4,5-b/pyridinderivat |
Country Status (17)
Country | Link |
---|---|
JP (1) | JPS5943475B2 (sv) |
AR (1) | AR208500A1 (sv) |
AT (1) | AT333277B (sv) |
AU (1) | AU472528B2 (sv) |
BE (2) | BE800868A (sv) |
CA (1) | CA1019741A (sv) |
CS (1) | CS178889B2 (sv) |
DD (1) | DD105237A5 (sv) |
DE (1) | DE2330109A1 (sv) |
DK (1) | DK152050C (sv) |
FI (1) | FI57417C (sv) |
FR (1) | FR2187356B1 (sv) |
GB (1) | GB1421619A (sv) |
LU (1) | LU67786A1 (sv) |
NL (1) | NL184836C (sv) |
SE (2) | SE401675B (sv) |
ZA (1) | ZA733760B (sv) |
Families Citing this family (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2527321A1 (de) * | 1975-06-19 | 1976-12-23 | Merck & Co Inc | Oxazol eckige klammer auf 4,5-b eckige klammer zu pyridine |
JPS527992A (en) * | 1975-07-04 | 1977-01-21 | Merck & Co Inc | Oxazolo *4*55b* pyridines |
NL187021C (nl) * | 1975-07-15 | 1991-05-01 | Merck & Co Inc | Werkwijze ter bereiding van een farmaceutisch preparaat met anti-inflammatoire werking, alsmede werkwijze ter bereiding van voor toepassing daarbij geschikte anti-inflammatoir werkzame 2-fenyl-oxazolo-(4,5-b)pyridinederivaten. |
US4011326A (en) * | 1975-07-29 | 1977-03-08 | Merck & Co., Inc. | 2-Substituted oxazolo[4,5-b]pyridine anti-inflammatory agents |
US4753673A (en) * | 1977-07-22 | 1988-06-28 | The Dow Chemical Company | Trifluoromethyl pyridinyloxyphenoxy and pyridinylthiophenoxy propanoic acids and propanols and derivatives thereof and methods of herbicidal use |
EP0001473B1 (en) * | 1977-08-12 | 1988-07-27 | Imperial Chemical Industries Plc | Herbicidal halogenomethyl--pyridyloxy-phenoxy-alkanecarboxylic acids and derivatives, and processes of controlling unwanted plants therewith |
JPS5461182A (en) * | 1977-10-20 | 1979-05-17 | Ishihara Sangyo Kaisha Ltd | 2-phenoxy-5-trifluoromethylpyridine compounds |
JPS5461183A (en) * | 1977-10-21 | 1979-05-17 | Ishihara Sangyo Kaisha Ltd | 2-substituted-5-trifluoromethyl pyridine compounds |
EP0003877B1 (en) * | 1978-02-15 | 1988-02-03 | Imperial Chemical Industries Plc | Herbicidal derivatives of 2-(4(2-pyridyloxy)phenoxy)propane, processes for preparing them, and herbicidal compositions containing them |
JPS55130840U (sv) * | 1979-03-12 | 1980-09-16 | ||
JPS55124763A (en) * | 1979-03-19 | 1980-09-26 | Ishihara Sangyo Kaisha Ltd | 5-trifluoromethyl-2-pyridone derivative |
GB8333514D0 (en) * | 1983-12-16 | 1984-01-25 | Erba Farmitalia | Tetrahydrothiazolo(5 4-c)pyridine derivatives |
FR2652085A1 (fr) * | 1989-09-20 | 1991-03-22 | Science Organisation | Nouveau procede de synthese de derives d'oxazolopyridines. |
WO1998021209A1 (de) * | 1996-11-11 | 1998-05-22 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Neue imidazo- und oxazolopyridine |
SK18542000A3 (sk) * | 1998-06-04 | 2001-12-03 | Abbott Laboratories | Protizápalové zlúčeniny inhibujúce bunkovú adhéziu |
US6232320B1 (en) | 1998-06-04 | 2001-05-15 | Abbott Laboratories | Cell adhesion-inhibiting antiinflammatory compounds |
WO2000075145A1 (en) * | 1999-06-03 | 2000-12-14 | Abbott Laboratories | Cell adhesion-inhibiting antiinflammatory compounds |
AU2002216649A1 (en) * | 2000-10-31 | 2002-05-15 | Lynn Bonham | Benzoxazole lpaat- beta inhibitors and uses thereof |
US8093401B2 (en) | 2005-08-04 | 2012-01-10 | Sirtris Pharmaceuticals, Inc. | Sirtuin modulating compounds |
EP2388263A1 (en) | 2005-08-04 | 2011-11-23 | Sirtris Pharmaceuticals, Inc. | Imidazo[2,1-b]thiazole derivatives as sirtuin modulators |
US7855289B2 (en) | 2005-08-04 | 2010-12-21 | Sirtris Pharmaceuticals, Inc. | Sirtuin modulating compounds |
US8088928B2 (en) | 2005-08-04 | 2012-01-03 | Sirtris Pharmaceuticals, Inc. | Sirtuin modulating compounds |
CL2008001822A1 (es) | 2007-06-20 | 2009-03-13 | Sirtris Pharmaceuticals Inc | Compuestos derivados de tiazolo[5,4-b]piridina; composicion farmaceutica que comprende a dichos compuestos; y uso del compuesto en el tratamiento de la resistencia a la insulina, sindrome metabolico, diabetes, entre otras. |
US8795630B2 (en) * | 2008-08-29 | 2014-08-05 | Treventis Corporation | Butyrylcholinesterase ligands as diagnostic tools and treatment for diseases of the nervous system |
BRPI0922435A2 (pt) | 2008-12-19 | 2018-09-11 | Sirtris Pharmaceuticals Inc | "composto de tiazolopiridina moduladores de sirtuina, composição farmacêutica compreendendo o mesmo e seu uso." |
BR112012007237A2 (pt) * | 2009-09-30 | 2019-09-24 | Sumitomo Chemical Co | composição e método para controlar pragas artrópodes |
BR112013006016A2 (pt) * | 2010-09-15 | 2016-06-07 | Hoffmann La Roche | compostos de azabenzotiazol, composições e métodos de uso |
TW201234965A (en) * | 2010-12-24 | 2012-09-01 | Sumitomo Chemical Co | Fused heterocyclic compound and use for pest control thereof |
WO2015200650A1 (en) * | 2014-06-25 | 2015-12-30 | Epizyme, Inc. | Substituted benzene and 6,5-fused bicyclic heteroaryl compounds |
TR201815071T4 (tr) | 2014-12-02 | 2018-11-21 | Bayer Cropscience Ag | Zararlılarla mücadele maddesi olarak bisiklik bileşikler. |
WO2017127627A1 (en) * | 2016-01-21 | 2017-07-27 | The University Of North Carolina At Chapel Hill | Compounds for treatment of trypanosomes and neurological pathogens and uses thereof |
KR102440762B1 (ko) * | 2016-07-07 | 2022-09-05 | 호도가야 가가쿠 고교 가부시키가이샤 | 벤조아졸 고리 구조를 가지는 화합물 및 유기 일렉트로루미네센스 소자 |
-
1973
- 1973-03-12 AR AR248527A patent/AR208500A1/es active
- 1973-05-22 FI FI1657/73A patent/FI57417C/fi active
- 1973-05-24 DK DK284973A patent/DK152050C/da not_active IP Right Cessation
- 1973-05-25 SE SE7307412A patent/SE401675B/sv unknown
- 1973-05-30 NL NLAANVRAGE7307582,A patent/NL184836C/xx not_active IP Right Cessation
- 1973-06-04 AU AU56511/73A patent/AU472528B2/en not_active Expired
- 1973-06-04 ZA ZA00733760A patent/ZA733760B/xx unknown
- 1973-06-05 CA CA173,275A patent/CA1019741A/en not_active Expired
- 1973-06-08 AT AT508673A patent/AT333277B/de active
- 1973-06-11 GB GB2763273A patent/GB1421619A/en not_active Expired
- 1973-06-12 DD DD171559A patent/DD105237A5/xx unknown
- 1973-06-12 CS CS7300004243A patent/CS178889B2/cs unknown
- 1973-06-13 LU LU67786A patent/LU67786A1/xx unknown
- 1973-06-13 DE DE2330109A patent/DE2330109A1/de not_active Withdrawn
- 1973-06-13 BE BE132231A patent/BE800868A/xx not_active IP Right Cessation
- 1973-06-13 FR FR7321443A patent/FR2187356B1/fr not_active Expired
- 1973-06-14 JP JP48066453A patent/JPS5943475B2/ja not_active Expired
-
1974
- 1974-08-26 BE BE147896A patent/BE819177R/xx not_active IP Right Cessation
-
1976
- 1976-04-14 SE SE7604385A patent/SE432767B/sv not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
FI57417C (fi) | 1980-08-11 |
BE819177R (fr) | 1975-02-26 |
JPS4961195A (sv) | 1974-06-13 |
DD105237A5 (sv) | 1974-04-12 |
AT333277B (de) | 1976-11-10 |
SE7604385L (sv) | 1976-04-14 |
GB1421619A (en) | 1976-01-21 |
NL184836C (nl) | 1989-11-16 |
FR2187356A1 (sv) | 1974-01-18 |
DE2330109A1 (de) | 1974-01-03 |
FI57417B (fi) | 1980-04-30 |
CS178889B2 (en) | 1977-10-31 |
LU67786A1 (sv) | 1973-08-16 |
SE401675B (sv) | 1978-05-22 |
ZA733760B (en) | 1975-01-29 |
CA1019741A (en) | 1977-10-25 |
DK152050B (da) | 1988-01-25 |
FR2187356B1 (sv) | 1977-01-28 |
AU5651173A (en) | 1974-12-05 |
BE800868A (fr) | 1973-12-13 |
NL7307582A (sv) | 1973-12-18 |
AR208500A1 (es) | 1977-02-15 |
JPS5943475B2 (ja) | 1984-10-22 |
DK152050C (da) | 1988-07-18 |
ATA508673A (de) | 1976-03-15 |
AU472528B2 (en) | 1976-05-27 |
NL184836B (nl) | 1989-06-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
NUG | Patent has lapsed |
Ref document number: 7604385-0 Effective date: 19921204 Format of ref document f/p: F |